Identification of genes that are associated with DNA repeats in
... sequences, but without sequences related to known CRISPRs. The PATSCAN program allows disclosure of sequence-independent motifs in DNA, and we used this program to search the EMBL/GenBank database for CRISPR motifs. The algorithm used recognizes motifs of at least four direct repeats, 15–70 bp in si ...
... sequences, but without sequences related to known CRISPRs. The PATSCAN program allows disclosure of sequence-independent motifs in DNA, and we used this program to search the EMBL/GenBank database for CRISPR motifs. The algorithm used recognizes motifs of at least four direct repeats, 15–70 bp in si ...
The Genome of a Mongolian Individual Reveals
... Genghis Khan and his successors have played a major role in the last 1,000 years of human evolution. Known as a typical nomadic people, Mongolians have evolved into a modern day ethnic group with their own culture, language, life style (Komatsu et al. 2006, 2008, 2009), and phenotypic and physiologi ...
... Genghis Khan and his successors have played a major role in the last 1,000 years of human evolution. Known as a typical nomadic people, Mongolians have evolved into a modern day ethnic group with their own culture, language, life style (Komatsu et al. 2006, 2008, 2009), and phenotypic and physiologi ...
DNA Self-assembly Model for Matrix Addition Problem
... to create complex nano-scale patterns. Fujibayashi et al. [10] have used DNA tiles and DNA origami to grow crystals containing a cellular automaton pattern and proved that programmable molecular self-assembly may be sufficient to create a wide range of complex objects in one-pot reactions. Dwyer and ...
... to create complex nano-scale patterns. Fujibayashi et al. [10] have used DNA tiles and DNA origami to grow crystals containing a cellular automaton pattern and proved that programmable molecular self-assembly may be sufficient to create a wide range of complex objects in one-pot reactions. Dwyer and ...
Genome Rearrangements Caused by Depletion of Essential DNA
... cycle following gene-product depletion by promoter shut off (Yu et al. 2006). Spontaneous DNA damage was measured by the relocalization of the DNA damage checkpoint protein Ddc2 from a diffuse nuclear pattern to discrete subnuclear foci (Figure 1A) (Melo et al. 2001; Lisby et al. 2004). Following gr ...
... cycle following gene-product depletion by promoter shut off (Yu et al. 2006). Spontaneous DNA damage was measured by the relocalization of the DNA damage checkpoint protein Ddc2 from a diffuse nuclear pattern to discrete subnuclear foci (Figure 1A) (Melo et al. 2001; Lisby et al. 2004). Following gr ...
Identification of editing positions in the ndhB transcript from maize
... organelles share common components and/or mechanistic steps. This suggestion gains even further support from the observation that no transition from alanine codons (GCN) to valine codons (GUN) have been observed so far in both plant organellar editing systems. The existence of several positions in t ...
... organelles share common components and/or mechanistic steps. This suggestion gains even further support from the observation that no transition from alanine codons (GCN) to valine codons (GUN) have been observed so far in both plant organellar editing systems. The existence of several positions in t ...
A GENETIC LINKAGE MAP OF Phycomyces blakesleeanus
... this research the genome (version 1.1) was made up of 491 fragments. The genetic linkage map shows the arrangement of genes and genetic markers along the chromosomes as calculated by the frequency with which they are co-inherited together. The map can also provide information about the number of ch ...
... this research the genome (version 1.1) was made up of 491 fragments. The genetic linkage map shows the arrangement of genes and genetic markers along the chromosomes as calculated by the frequency with which they are co-inherited together. The map can also provide information about the number of ch ...
mutations
... of red blood cells. Normal red blood cells are round. Sickle cells appear long and pointed. Sickle cell disease is caused by a point mutation in one of the polypeptides found in hemoglobin, the blood’s principal oxygencarrying protein. Among the symptoms of the disease are anemia, severe pain, frequ ...
... of red blood cells. Normal red blood cells are round. Sickle cells appear long and pointed. Sickle cell disease is caused by a point mutation in one of the polypeptides found in hemoglobin, the blood’s principal oxygencarrying protein. Among the symptoms of the disease are anemia, severe pain, frequ ...
How dormant origins promote complete genome replication
... [41]. It shows how dormant origins protect against double fork stalls (Figure 3b) that leave unreplicatable sections of DNA between them. Interestingly, the model shows that the density of licensed origins on DNA determines the degree of protection against double fork stalling, with the efficiency o ...
... [41]. It shows how dormant origins protect against double fork stalls (Figure 3b) that leave unreplicatable sections of DNA between them. Interestingly, the model shows that the density of licensed origins on DNA determines the degree of protection against double fork stalling, with the efficiency o ...
Drug-specific Sites of Topoisomerase II DNA
... topoisomerase II (Fig. 1B). Interestingly, VM-26 stimulated a very (35), and several dh-EPI sites were localized in nucleosomal DNA strong cleavage site once per repeat that appearsto be the sameas that linkers (Fig. 2), in agreementwith publisheddata(19, 36). Neverthe observed in vivo. The dh-Epi-s ...
... topoisomerase II (Fig. 1B). Interestingly, VM-26 stimulated a very (35), and several dh-EPI sites were localized in nucleosomal DNA strong cleavage site once per repeat that appearsto be the sameas that linkers (Fig. 2), in agreementwith publisheddata(19, 36). Neverthe observed in vivo. The dh-Epi-s ...
Cutting Edge: DNA Polymerases and Are Dispensable for Ig Gene
... excluded its participation in the mutation process (5). Over the past 4 years, nine additional DNA polymerases (if one includes Rev1, a deoxycytidyl transferase) have been identified (reviewed in Ref. 2). Although many of these enzymes have bacterial or yeast homologs with known repair function, the ...
... excluded its participation in the mutation process (5). Over the past 4 years, nine additional DNA polymerases (if one includes Rev1, a deoxycytidyl transferase) have been identified (reviewed in Ref. 2). Although many of these enzymes have bacterial or yeast homologs with known repair function, the ...
Evolutionary Origin and Adaptive Function of Meiosis
... cens, a red algae, existed more than 1.2 billion years ago and was sexually reproducing (Butterfield, 2000). Although meiotic sex is widespread among extant eukaryotes, it has, until recently, been unclear whether or not eukaryotes were sexual early in their evolution. The reason for this uncertaint ...
... cens, a red algae, existed more than 1.2 billion years ago and was sexually reproducing (Butterfield, 2000). Although meiotic sex is widespread among extant eukaryotes, it has, until recently, been unclear whether or not eukaryotes were sexual early in their evolution. The reason for this uncertaint ...
The rapidly evolving field of plant centromeres
... satellite evolution is driven by the selection and coevolution of satellites and centromere-binding proteins, rather than by random genetic drift. This requires that certain centromere satellite variants confer a selective advantage upon meiotic cells (i.e. eggs and sperm), a process known as meioti ...
... satellite evolution is driven by the selection and coevolution of satellites and centromere-binding proteins, rather than by random genetic drift. This requires that certain centromere satellite variants confer a selective advantage upon meiotic cells (i.e. eggs and sperm), a process known as meioti ...
Horizontal transfer of non-LTR retrotransposons: artifact or rare event
... for HT detection. Multiple TEs lineages can be present within genomes. Moreover, TEs are multicopy components of genomes. Comparisons of paralogous TE copies instead of orthologs along with varying rates of their sequence evolution are the main sources for incongruence in phylogenetic analysis, whic ...
... for HT detection. Multiple TEs lineages can be present within genomes. Moreover, TEs are multicopy components of genomes. Comparisons of paralogous TE copies instead of orthologs along with varying rates of their sequence evolution are the main sources for incongruence in phylogenetic analysis, whic ...
ACLS CH05 - CTCE Moodle
... FIGURE 35-5 DNA holds the individual genetic code for each person. Each strand of DNA is made up of a series of nucleotides. The sequence of nucleotides determines which protein is synthesized. (Courtesy Joan M. Beck.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier ...
... FIGURE 35-5 DNA holds the individual genetic code for each person. Each strand of DNA is made up of a series of nucleotides. The sequence of nucleotides determines which protein is synthesized. (Courtesy Joan M. Beck.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier ...
Genome
... Enter chr3:10,181,000-10,196,000 into input box and click go. Right click on tracks NOT shown below and hide them. Right click on the RepeatMasker track and click full. It is dense by default. Adjust the zoom until you get a view you are comfortable with. ...
... Enter chr3:10,181,000-10,196,000 into input box and click go. Right click on tracks NOT shown below and hide them. Right click on the RepeatMasker track and click full. It is dense by default. Adjust the zoom until you get a view you are comfortable with. ...
unit-2 genetics of prokaryotes and eukaryotic
... enzymes needed for synthesis of new viral DNA molecules are produced. At 8 minutes, some 40 different structural proteins for the viral head and tail are synthesized. At 13 minutes, assembly of new viral particles begins. At 25 minutes, the viral lysozyme destroys the bacterial cell wall and the vir ...
... enzymes needed for synthesis of new viral DNA molecules are produced. At 8 minutes, some 40 different structural proteins for the viral head and tail are synthesized. At 13 minutes, assembly of new viral particles begins. At 25 minutes, the viral lysozyme destroys the bacterial cell wall and the vir ...
Uracil in DNA – occurrence, consequences and repair
... the spontaneous mutation level in Ung7/7 mice was increased only 1.3-fold (thymus) and 1.4-fold (spleen) as compared with wild type. This is likely due to the presence of back-up activities, among which SMUG1 may have a dominant role (Nilsen et al., 2000, 2001). While these results are seemingly at ...
... the spontaneous mutation level in Ung7/7 mice was increased only 1.3-fold (thymus) and 1.4-fold (spleen) as compared with wild type. This is likely due to the presence of back-up activities, among which SMUG1 may have a dominant role (Nilsen et al., 2000, 2001). While these results are seemingly at ...
to the complete text - David Moore`s World of Fungi
... frequency measurements such as these might have standard errors of about 10% of the value stated in the table, in which case this additivity equation would be more realistically stated as [(15 ± 1.5) + (5 ± 0.5) = 18 ± 1.8]. So we are reasonably satisfied with the map for these three genes. That’s ...
... frequency measurements such as these might have standard errors of about 10% of the value stated in the table, in which case this additivity equation would be more realistically stated as [(15 ± 1.5) + (5 ± 0.5) = 18 ± 1.8]. So we are reasonably satisfied with the map for these three genes. That’s ...
Document
... Repeat tracks are 3’ to the gene, 5’ to the gene, or in the intronic region. This validates our hypothesis. ALUs are not the only family of SINEs located in the intronic regions. What other SINE families does VHL have? What about other TE classes other than SINE? (Answers provided in separate pdf) J ...
... Repeat tracks are 3’ to the gene, 5’ to the gene, or in the intronic region. This validates our hypothesis. ALUs are not the only family of SINEs located in the intronic regions. What other SINE families does VHL have? What about other TE classes other than SINE? (Answers provided in separate pdf) J ...
RECOMBINEERING: A POWERFUL NEW TOOL FOR MOUSE
... strains is that the recombination pathway is constitutively active in them, causing rearrangements and deletions between the repeat sequences that are found in most BAC and PAC clones. Chi-stimulated recombination. Chi-stimulated recombination provides a way to modify genomes with linear dsDNA in wi ...
... strains is that the recombination pathway is constitutively active in them, causing rearrangements and deletions between the repeat sequences that are found in most BAC and PAC clones. Chi-stimulated recombination. Chi-stimulated recombination provides a way to modify genomes with linear dsDNA in wi ...
SAY IT WITH DNA: PROTEIN SYNTHESIS WORKSHEET: Practice
... 2. Be sure that students understand the significance of controlling protein production, namely the "One Gene - One Enzyme" concept: each step of a biochemical series of reactions requires a unique enzyme which in turn is the product of one gene. If the gene is there, the enzyme can be produced, ...
... 2. Be sure that students understand the significance of controlling protein production, namely the "One Gene - One Enzyme" concept: each step of a biochemical series of reactions requires a unique enzyme which in turn is the product of one gene. If the gene is there, the enzyme can be produced, ...
Microbial DNA qPCR Assays
... may be up to a thousand different microbial species, each assay was tested using stool, tooth plaque, and sputum samples. For each sample, synthetic template targets were spiked in and the CT was compared to synthetic template alone. PCR was performed using several sample types, which included poole ...
... may be up to a thousand different microbial species, each assay was tested using stool, tooth plaque, and sputum samples. For each sample, synthetic template targets were spiked in and the CT was compared to synthetic template alone. PCR was performed using several sample types, which included poole ...
Mitochondrial DNA
Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, adenosine triphosphate (ATP). Mitochondrial DNA is only a small portion of the DNA in a eukaryotic cell; most of the DNA can be found in the cell nucleus and, in plants, in the chloroplast.In humans, mitochondrial DNA can be assessed as the smallest chromosome coding for 37 genes and containing approximately 16,600 base pairs. Human mitochondrial DNA was the first significant part of the human genome to be sequenced. In most species, including humans, mtDNA is inherited solely from the mother.The DNA sequence of mtDNA has been determined from a large number of organisms and individuals (including some organisms that are extinct), and the comparison of those DNA sequences represents a mainstay of phylogenetics, in that it allows biologists to elucidate the evolutionary relationships among species. It also permits an examination of the relatedness of populations, and so has become important in anthropology and field biology.