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Microbial Genetics - MyCourses
Microbial Genetics - MyCourses

... Structure of the operon. The operon consists of the promoter (P) and operator (O) sites and structural genes that code for the protein. The operon is regulated by the product of the regulatory gene (I) ...
University of Groningen DNA-based asymmetric catalysis
University of Groningen DNA-based asymmetric catalysis

... with enzymes. Although small molecule catalysts can have high catalytic activity, they are generally still outperformed by enzymes. However, the possibility to catalyze a wide variety of reactions, renders small molecule catalysts very important for applications of asymmetric catalysis in industry,8 ...
The Two Faces of Higher Eukaryotic DNA Replication Origins
The Two Faces of Higher Eukaryotic DNA Replication Origins

... the minibubbles must span the origin of bidirectional replication. The second observation possibly inconsistent with the model is that the shortest nascent leading strands appear to become progressively longer at increasing distances from the origin of bidirectional replication (Vassilev et al., 199 ...
PDF - The Journal of General Physiology
PDF - The Journal of General Physiology

... Release of DNA.--In Table I the results are given of star counting on the unseparated material resulting from osmotic shock, urea, pyrophosphate, and arginine treatment. In each case the specific viscosity increased to the value listed at the top of the table. Since prolonged treatment did not produ ...
Document
Document

... • Relatively easy to generate and renew • Infect a wide variety of cell types • Potential for in vivo gene delivery ...
The DNA chromatin condensation expressed by the image optical
The DNA chromatin condensation expressed by the image optical

... chromosomes with silent genes. Since the number of mitotic myeloblasts in the bone marrow of not-leukemic patients is small, the heterochromatin DNA ID in central as well as peripheral nuclear regions and mitotic chromosomes was measured in bone marrow mitotic granulocytic progenitors of patients su ...
Host DNA Replication Is Induced by Geminivirus
Host DNA Replication Is Induced by Geminivirus

... Mammalian DNA tumor viruses establish permissive conditions for DNA replication by inactivating tumor suppressor proteins, such as pRb and p53, and upregulating DNA replication-associated proteins, such as PCNA (Nevins, 1992; Jansen-Durr, 1996). TGMV may use a similar strategy because the TGMV AL1 p ...
Energetics of protein–DNA interactions
Energetics of protein–DNA interactions

... Received August 15, 2006; Revised December 1, 2006; Accepted December 4, 2006 ...
08_Human_chromosomes(plain)
08_Human_chromosomes(plain)

... during mitosis and meiosis, this DNA molecule is compacted into a chromosome approximately 5µm long. Although this compaction makes it easier to transport DNA within a dividing cell, it also makes DNA less accessible for other cellular functions such as DNA synthesis and transcription. Thus, chromos ...
1 - life.illinois.edu
1 - life.illinois.edu

... are resistant to both K and P1 restriction systems. b. In a second experiment, they labeled lambda DNA of phage growing in E. coli K (P1) with 32P so that the newly synthesized DNA in the phage was radioactive. They then infected E. coli K cells with the radioactive phage in medium containing nonrad ...
Chapter 3: Molecular Biology Problems
Chapter 3: Molecular Biology Problems

... substance away from other cellular material and then determine whether it was pure DNA or a mixture of protein and DNA. They hoped to show that protein was either not present or not essential for the transforming substance to be able to transform R to S. b) If they had found traces of protein in the ...
Biological-Anthropology-2nd-Edition-Stanford-Test-Bank
Biological-Anthropology-2nd-Edition-Stanford-Test-Bank

Article PDF
Article PDF

... nucleosome particle and mediate interactions between proximal nucleosomes.12 Post-translational modifications of these tails, which alter their electrostatics, are among the primary mechanisms regulating chromatin folding.12,13 It was recently suggested that a specific localized acidic patch on the ...
A Sex Chromosome Rearrangement in a Human XX
A Sex Chromosome Rearrangement in a Human XX

... recombination point on the X is likely to lie within the pseudoautosomal region (Page et al., 1987a). Taken together, these studies show that in Y(+)XX males the positions of both the Yp and Xp breakpoints are variable. All eight Y(+)XX males examined to date apparently result from single erroneous ...
Nucleotide Sequence Preservation of Human
Nucleotide Sequence Preservation of Human

... sequence comparisons of the D-loop region of unrelated normal humans (5, 21). Three additional between-individual differences outside the Dloop region of mtDNA were identified in this study. Substitution of cytidine for thymidine at L-strand positions 9698 and 9725 was found in all clones containing ...
Magnusiomyces capitatus (de Hoog et al.) de Hoog et Smith
Magnusiomyces capitatus (de Hoog et al.) de Hoog et Smith

... This product is intended for laboratory research purposes only. It is not intended for use in humans. While ATCC uses reasonable efforts to include accurate and up­to­date information on this product sheet, ATCC makes no warranties or representations as to its accuracy. Citations from scientific lit ...
Molecular targets of oxidative stress
Molecular targets of oxidative stress

... contributor to ROS-induced killing, especially in eukaryotic cells. (Note that this section concentrates primarily on the situation of toxicity in single cells, but it must not be overlooked that mutation in a single cell within a higher animal can give rise to a dominant cell population which ultim ...
Minireview Alpha Satellite and the Quest for the Human Centromere
Minireview Alpha Satellite and the Quest for the Human Centromere

... (125 bp) DNA sequence whose overall organization and sequence composition are highly conserved among the 16 different centromeres. The apparent dependence on primary DNA sequence is reminiscent of transcriptional regulation—specific sequences bind specific proteins, which in this case mediate chromo ...
letters
letters

... The establishment and maintenance of epigenetic gene silencing is fundamental to cell determination and function1. The essential epigenetic systems involved in heritable repression of gene activity are the Polycomb group (PcG) proteins2,3 and the DNA methylation4,5 systems. Here we show that the cor ...
Chapter 1: The Genetic Approach to Biology Questions for Chapter 1
Chapter 1: The Genetic Approach to Biology Questions for Chapter 1

Genomic imprinting and human disease
Genomic imprinting and human disease

... of kilobases (kb) in size. Imprinted gene expression across these evolutionarily conserved clusters is regulated by ICRs (imprinting control regions), essential DNA sequence elements that are up to several kilobases in size. ICRs are CpG-rich regions that are methylated only on one of the two parent ...
Isolation of a gene encoding a novel chloroplast protein by T
Isolation of a gene encoding a novel chloroplast protein by T

... 156 offspring tested were hygromycin resistant but split to 79 green and 77 pale. The 1:1 segregation ratio of green and pale Fl progenies confirmed (P = 0.86) the allelism and the absence of complementation between cs and ch-42 mutations, permitting cs to be assigned to position 39.4-4 of ch-42 on ...
Nuclear and Nucleolar Localization by the N
Nuclear and Nucleolar Localization by the N

... rDNA templating (11, 14, 32, 47). Nucleolar egress of topoIN-EGFP following treatment with transcriptional inhibitors suggests that retention of topo I within the nucleolar milieu is dependent on ongoing rRNA synthesis. DRB inhibits RNA transcription driven by all three RNA polymerases (5), while Ac ...
Practice exam 2 key
Practice exam 2 key

... The following table contains a list of statements that apply to replication, transcription, both, or neither. In each empty box, put a check mark if that statement applies to replication or transcription. In eukaryotes, the process occurs in the nucleus. A primer is required to initiate synthesis. T ...
Oxidative DNA Damage Bypass in Arabidopsis thaliana Requires
Oxidative DNA Damage Bypass in Arabidopsis thaliana Requires

... alkylating agents endogenously generated by metabolism (Britt, 1999). DNA is also damaged because of errors during its replication. The DNA lesions produced by these damaging agents may result in base change, base loss, base mismatch, base deletion or insertion, linked pyrimidines, strand breaks, an ...
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DNA damage theory of aging

The DNA damage theory of aging proposes that aging is a consequence of unrepaired accumulation of naturally occurring DNA damages. Damage in this context is a DNA alteration that has an abnormal structure. Although both mitochondrial and nuclear DNA damage can contribute to aging, nuclear DNA is the main subject of this analysis. Nuclear DNA damage can contribute to aging either indirectly (by increasing apoptosis or cellular senescence) or directly (by increasing cell dysfunction).In humans and other mammals, DNA damage occurs frequently and DNA repair processes have evolved to compensate. In estimates made for mice, on average approximately 1,500 to 7,000 DNA lesions occur per hour in each mouse cell, or about 36,000 to 160,000 per cell per day. In any cell some DNA damage may remain despite the action of repair processes. The accumulation of unrepaired DNA damage is more prevalent in certain types of cells, particularly in non-replicating or slowly replicating cells, such as cells in the brain, skeletal and cardiac muscle.
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