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Towards better patient care: drugs to avoid in 2016
Towards better patient care: drugs to avoid in 2016

... –  The new drug is compared with a carefully chosen standard treatment (not necessarily a drug); – The accent is placed on those clinical endpoints most relevant to the patients concerned. This means that we often ignore surrogate endpoints such as simple laboratory markers that have not been shown ...
Prescription_Medications
Prescription_Medications

... include stomach pain, gas, diarrhea, and leakage of oily stool. These side effects are generally mild and temporary, but may be worse when you eat highfat foods. You should eat a low-fat diet (less than 30 percent of calories from fat) before starting to take this drug. Because orlistat prevents som ...
the facts on marijuana
the facts on marijuana

EPILEPSY
EPILEPSY

... • DRUG WITH DRAWAL ...
Immunodeficiencies and autoimmune diseases
Immunodeficiencies and autoimmune diseases

... • Drug induced immunodeficiencies (chemotherapy) • Immunosupressive therapy • Chronic stress • Chronic exposure to harmful chemical substances ...
full text pdf
full text pdf

... bond acceptors, had a molecular weight less than 500 grams per mole, and had an octanol-water partition coefficient (log P) of less than five. These rules are used as a guideline to focus the screening process and new drugs tend to be small organic molecules with high affinity for their target as we ...
Use of ophthalmic medications during pregnancy
Use of ophthalmic medications during pregnancy

... as treatment is stopped at the time of delivery.4 A casecontrol study also showed that chloramphenicol poses minimal teratogenic risk to a foetus whose mother has received the drug orally, even during early pregnancy.5 Quinolone, gentamicin, and erythromycin are very important ophthalmic antibiotics ...
Generic Drugs: Questions and Answers
Generic Drugs: Questions and Answers

... are chemically identical to their branded counterparts, they are typically sold at substantial discounts from the branded price. According to the Congressional Budget Office, generic drugs save consumers an estimated $8 to $10 billion a year at retail pharmacies. Even more billions are saved when ho ...
ThromboGenics Highlights Diabetic Eye Drug Developments at
ThromboGenics Highlights Diabetic Eye Drug Developments at

... particularly diabetic retinopathy (DR) and diabetic macular edema (DME). Over the last two years, ThromboGenics has developed an attractive pipeline of disease modifying drug candidates. The pipeline consists of THR-409, THR-317, both from its in-house research, as well as THR-149 which resulted fro ...
Triple Diagnosis: HIV, Substance Abuse and Mental Illness
Triple Diagnosis: HIV, Substance Abuse and Mental Illness

... DSM-IV Criteria determine dependence by finding evidence of  physical or psychologic dependence on a drug or tolerance to it  disruption of social life patterns  disregard of the negative medical consequences of using drugs ...
Acid-Base Properties of Drugs - NSU College of Pharmacy
Acid-Base Properties of Drugs - NSU College of Pharmacy

... Fig.2.10. A weak base like pyrimethamine is trapped in the urine when the latter is more acidic than the blood. The diffusible uncharged form of the drug equilibrates across the membrane, however, the total concentration (charged plus uncharged) in the urine is almost eight times higher than in the ...
Urine Drug Toxicology and Pain Management Testing
Urine Drug Toxicology and Pain Management Testing

... 1) In a patient prescribed Tylenol #3, one would expect which of the following to be detectable in the urine? (29% correct) 2) In a patient prescribed MSContin, one would reasonably expect to find which of the following in the urine? (61% correct) 3) In a patient abusing heroin, one would be likely ...
GNRS4Addictions - Geriatrics Care Online
GNRS4Addictions - Geriatrics Care Online

PROVISIONAL ANSWER KEY NAME OF THE POST
PROVISIONAL ANSWER KEY NAME OF THE POST

Composition Each tablet contains: Sennosides 7.5 mg Properties
Composition Each tablet contains: Sennosides 7.5 mg Properties

... constipation may be due to the effort itself when trying to evacuate the bowel. 3- As laxative prior to gut investigation. 4- Constipation in elderly, pregnancy and puerperium and slow transit constipation. 5- As adjunct to anthelmintic therapy. Drug Interactions No major drug interactions have been ...
Acute Effects of d-Amphetamine on the Differential Reinforcement of
Acute Effects of d-Amphetamine on the Differential Reinforcement of

... Amphetamine, in general, causes rats to respond with shorter IRTs leading a leftward shift in the IRT frequency distribution. Although the pharmacological properties remain controversial, it has been suggested that these behavioral changes in the DRL schedule produced by amphetamine are predominatel ...
Sponsor vs. Investigator
Sponsor vs. Investigator

... described in the approved labeling.  Off-label therapy with cancer drugs is relatively common in practice. ...
Itraconazole
Itraconazole

... Absorption is impaired when gastric acidity is reduced. In patients receiving acid neutralizing medicines (e.g. aluminium hydroxide), these should be administered at least 2 hours after the intake of Itraconazole. The drug should be administered after a full meal. Rarely, cases of hepatitis and jaun ...
PDF
PDF

... Office of Surveillance and Epidemiology Center for Drug Evaluation and Research Safety, Value and Innovation Seminar Center for Drug Safety and Effectiveness Johns Hopkins Bloomberg School of Public Health ...
M.Pharm. Dissertation protocol
M.Pharm. Dissertation protocol

... 5) Khazaeli et al.,have developed Formulation of ibuprofen beads to reduce its gastric ulcerogenicity. Hence, Ca-alginate ibuprofen beads, through ionotropic gelation have been investigated. For this purpose, different cross- linking agents including: Ca2+, Ba2+, Mn2+, Co2+, Sn2+ and Pb2+, were used ...
3-Treatment of dysentery and amoebiasis2016-12-20
3-Treatment of dysentery and amoebiasis2016-12-20

... both bacillary dysentery and amebic dysentery. To be able to describe actions, side effects of drugs for treating bacillary dysentery. To understand the pharmacokinetics, actions, clinical applications and side effects of antiamebic drugs. To be able to differentiate between types of antiamebic drug ...
What is polypharmacy
What is polypharmacy

... The NSAIDs audit will provide community pharmacists with a tool to check their current practice for supply of these medications. The audit on NSAIDs contains a step-by-step guide for pharmacists and non-pharmacist staff when either a patient requests an over-the-counter NSAID, or presents with sympt ...
Immunodeficiencies and autoimmune diseases
Immunodeficiencies and autoimmune diseases

... • Drug induced immunodeficiencies (chemotherapy) • Immunosupressive therapy • Chronic stress • Chronic exposure to harmful chemical substances ...
Why is marijuana illegal
Why is marijuana illegal

... cigarette smokers, but yet cigs are still legal? What about alcohol? MJ has been around for over 5000 years, and until recently nobody had a problem with it. Government propaganda has trained the American society to believe that this drug is so detrimental to progress in society and users should be ...
What is Indication Extrapolation?
What is Indication Extrapolation?

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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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