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IN SITU IMPLANTS FOR PARENTERAL ADMINISTRATION    Research Article
IN SITU IMPLANTS FOR PARENTERAL ADMINISTRATION    Research Article

... The  efficiency  of  any  drug  therapy  can  be  described  by  achieving  desired  concentration  of  the  drug  in  blood  or  tissue,  which  is  therapeutically effective and  non toxic  for a  prolonged period. This  goal  can  be  achieved  on  the  basis  of  proper  design  of  the  dosage  ...
A novel, highly potent HER2-targeted antibody
A novel, highly potent HER2-targeted antibody

... 1+/2+). XMT-1522 is an anti-HER2 ADC that uses a novel, human anti-HER2 antibody optimized for cytotoxic payload delivery, and is non-competitive with trastuzumab or pertuzumab for HER2 binding. Each antibody is conjugated to ~15 proprietary auristatin molecules using Fleximer, a biodegradable hydro ...
Pharmacologically Active Metabolites of Currently - J
Pharmacologically Active Metabolites of Currently - J

... propranolol,15) risperidone,16) itraconazole,17) and bupropion (Fig. 1(b))18) generate their active metabolites via aromatic or aliphatic hydroxylations. Bupropion also forms two other active metabolites, namely threohydrobupropion and erythrohydrobupropion through carbonyl reduction.18) O-Demethyla ...
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... This research was performed to study the effects of Citicholine Sodium on the anaesthesia induced by Thiopental Sodium and the changes occurred on the parameters such as heart rate , respiration rate, Spo2 and rectal temperature. In the present study after injection of Thiopental an increase was see ...
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... These parasites can originate two types of diseases: visceral or cutaneous leishmaniases.Although the visceral form is more aggressive, the cutaneous leishmaniases (CL) has received considerable attention in recent research because most patients are resistant to current treatments [4]. The first- li ...
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... States. It has been estimated that over 33 million women worldwide received Bendectin. Despite the drug's enormous popularity, questions about Bendectin's safety continued to trickle in to the company and drug regulatory agencies around the world. The company's standard reply to physicians reporting ...
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... DTC - direct to consumer advertising • The European Parliament voted against the Commissions proposal to allow companies to communicate directly with consumers about some prescription medicines. A personal view: • No inhibition of Internet sites that discuss drug treatment. • Advertising in public ...
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... with treatment of alcoholism alone, improved alcohol use and social anxiety for clients with dual diagnoses of social anxiety disorder and alcohol dependence. METHODS: The design was a two-group, randomized clinical trial that used 12 weeks of individual cognitive behavioral therapy for alcoholism o ...
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Certified Medication Technician Student Manual

... medication is administered, it goes through several steps before it is excreted from the body. While it is in the body the drug can act either locally or systemically. In order to safely administer medications in a long term care setting, the medication technician must have an understanding of basic ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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