TFP5/TP5 peptide provides neuroprotection in the MPTP model of
... Cyclin-dependent kinase 5 (Cdk5) is a member of the serine-threonine kinase family of cyclin-dependent kinases. Cdk5 is critical to normal mammalian nervous system development and plays important regulatory roles in multiple cellular functions. Recent evidence indicates that Cdk5 is inappropriately ...
... Cyclin-dependent kinase 5 (Cdk5) is a member of the serine-threonine kinase family of cyclin-dependent kinases. Cdk5 is critical to normal mammalian nervous system development and plays important regulatory roles in multiple cellular functions. Recent evidence indicates that Cdk5 is inappropriately ...
Differential expression of galanin in the cholinergic basal forebrain
... exists as either 19 or 30-amino acid long isoforms (in contrast to 29 amino acid long as first extracted from porcine intestines) [11–13]. Galanin is known to participate in the regulation of several neuroendocrine [14] and neurotransmitter systems [15, 16] via three galanin G-protein coupled recept ...
... exists as either 19 or 30-amino acid long isoforms (in contrast to 29 amino acid long as first extracted from porcine intestines) [11–13]. Galanin is known to participate in the regulation of several neuroendocrine [14] and neurotransmitter systems [15, 16] via three galanin G-protein coupled recept ...
2006; 15: 618–627 pharmacoepidemiology and drug safety
... consensus shifted to acknowledge that opioid analgesics had a legitimate and important role in managing chronic pain.12–15 This change in thinking probably contributed to the dramatic increase in prescriptions written for opioid analgesics from 1990 to 2002.16–18 Opioid analgesics include semisynthe ...
... consensus shifted to acknowledge that opioid analgesics had a legitimate and important role in managing chronic pain.12–15 This change in thinking probably contributed to the dramatic increase in prescriptions written for opioid analgesics from 1990 to 2002.16–18 Opioid analgesics include semisynthe ...
Research That Revolutionized Patient Care
... The American Society of Hematology (ASH) turns 50 in 2008, and we look back with pride and awe at the momentous changes in our field during the last half century. The explosive progress in the field of molecular biology has yielded fundamental insights into the origin of human diseases and sparked t ...
... The American Society of Hematology (ASH) turns 50 in 2008, and we look back with pride and awe at the momentous changes in our field during the last half century. The explosive progress in the field of molecular biology has yielded fundamental insights into the origin of human diseases and sparked t ...
side effect
... • IT SEEMS TO BE MORE EFFECTIVE IN CHILDREN THAN IN ADULTS • IT IS MORE EFFECTIVE WHEN EMPLOYING HIGH DOSE SINGLE-ALLERGEN THERAPY IT MUST BE APPLILED BY A SPECIALIST ...
... • IT SEEMS TO BE MORE EFFECTIVE IN CHILDREN THAN IN ADULTS • IT IS MORE EFFECTIVE WHEN EMPLOYING HIGH DOSE SINGLE-ALLERGEN THERAPY IT MUST BE APPLILED BY A SPECIALIST ...
Preventing Medication Errors
... care. Mistakes can occur at various points in each phase of the medication administration process: prescription, transcription, and administration. ...
... care. Mistakes can occur at various points in each phase of the medication administration process: prescription, transcription, and administration. ...
Effects of UN and Russian Influence on Drug Policy in Central Asia
... The third part therefore analyzes regional cooperation on drug control, with a focus on the two model laws on drugs adopted by the Inter-Parliamentary Assembly of the Commonwealth of Independent States (CIS), which largely replicate Russian policy. In the fourth part, a brief analysis of national d ...
... The third part therefore analyzes regional cooperation on drug control, with a focus on the two model laws on drugs adopted by the Inter-Parliamentary Assembly of the Commonwealth of Independent States (CIS), which largely replicate Russian policy. In the fourth part, a brief analysis of national d ...
Neuromodulation for Failed Back Surgery
... between ratings of pain, disability, mood, and quality of life. The use of a multi-dimensional outcomes approach revealed a number of inconsistencies in the data which could have been overlooked using only pain ratings and patient satisfaction data. No one treatment emerged as the most effective acr ...
... between ratings of pain, disability, mood, and quality of life. The use of a multi-dimensional outcomes approach revealed a number of inconsistencies in the data which could have been overlooked using only pain ratings and patient satisfaction data. No one treatment emerged as the most effective acr ...
Rapid tranquillisation - The British Journal of Psychiatry
... Acute behavioural disturbance in psychiatric patients may require urgent treatment. This may result from psychotic symptoms, such as persecutory delusions or command hallucinations, or alternatively from nonpsychotic symptoms such as high levels of anxiety (Atakan & Davies, 1997). The clinical manag ...
... Acute behavioural disturbance in psychiatric patients may require urgent treatment. This may result from psychotic symptoms, such as persecutory delusions or command hallucinations, or alternatively from nonpsychotic symptoms such as high levels of anxiety (Atakan & Davies, 1997). The clinical manag ...
LATG Pharmacology (Ch. 16)
... • Sensitization: increase in response (e.g., allergic reactions) • Synergistic: two or more drug which give an enhanced response (e.g., antibiotics) • Potentiation: increased action by one drug produced by another drug with nonrelated action ...
... • Sensitization: increase in response (e.g., allergic reactions) • Synergistic: two or more drug which give an enhanced response (e.g., antibiotics) • Potentiation: increased action by one drug produced by another drug with nonrelated action ...
LATG Pharmacology (Ch. 16)
... • Sensitization: increase in response (e.g., allergic reactions) • Synergistic: two or more drug which give an enhanced response (e.g., antibiotics) • Potentiation: increased action by one drug produced by another drug with nonrelated action ...
... • Sensitization: increase in response (e.g., allergic reactions) • Synergistic: two or more drug which give an enhanced response (e.g., antibiotics) • Potentiation: increased action by one drug produced by another drug with nonrelated action ...
Switching from lisinopril to valsartan
... Heart Failure, Left Ventricular Dysfunction, or Both. Marc A. Pfeffer, M.D. Some people taking lisinopril may experience a dry cough that doesn't go away. But as this eMedTV Web page explains, there's no way to know if and when a lisinopril. Snfficiency brain teasers for seniors indictment for forge ...
... Heart Failure, Left Ventricular Dysfunction, or Both. Marc A. Pfeffer, M.D. Some people taking lisinopril may experience a dry cough that doesn't go away. But as this eMedTV Web page explains, there's no way to know if and when a lisinopril. Snfficiency brain teasers for seniors indictment for forge ...
Influence of ketamine on amino acid neurotransmitters secretion by
... of neurons. The anesthetics enhance the central inhibitory neurotransmission mediated by the GABAA receptor–channel complex (Tanelian et al., 1993). The anesthesia induced by ketamine was also considered to work by enhancing the GABA inhibitory neurotransmission in the central nervous system (Irifun ...
... of neurons. The anesthetics enhance the central inhibitory neurotransmission mediated by the GABAA receptor–channel complex (Tanelian et al., 1993). The anesthesia induced by ketamine was also considered to work by enhancing the GABA inhibitory neurotransmission in the central nervous system (Irifun ...
Evaluation of H1-Antihistamine usage among dermatology
... least risk for adverse events is essential. Hence the present study was undertaken to evaluate the pattern of H1antihistamine usage in dermatology, in order to identify any irrationality and to suggest measures for their better and rational use. 112 case files belonging to patients admitted in the d ...
... least risk for adverse events is essential. Hence the present study was undertaken to evaluate the pattern of H1antihistamine usage in dermatology, in order to identify any irrationality and to suggest measures for their better and rational use. 112 case files belonging to patients admitted in the d ...
Molecular Genetic Studies of Eating Disorders
... Association studies identify genes that contribute to disorders. These designs are conceptually equivalent to case-control studies in which individuals with eating disorders are compared to controls in terms of their allele (alternate form of a gene) and genotype (the combination of alleles) frequen ...
... Association studies identify genes that contribute to disorders. These designs are conceptually equivalent to case-control studies in which individuals with eating disorders are compared to controls in terms of their allele (alternate form of a gene) and genotype (the combination of alleles) frequen ...
Rational Drug Design Approach to Synthesizing HIV-1 Protease Inhibitors
... renders the 184V mutant protease capable of producing a virus with 102 to 103 fold decreased sensitivity to an inhibitor, Bila 2011 (Erickson et al. 1996). But because most drug resistant mutations occur at the active site, in theory, only a limited number of mutations can be supported by the virus ...
... renders the 184V mutant protease capable of producing a virus with 102 to 103 fold decreased sensitivity to an inhibitor, Bila 2011 (Erickson et al. 1996). But because most drug resistant mutations occur at the active site, in theory, only a limited number of mutations can be supported by the virus ...
CHAPTER 6
... where, from for the sake of simplicity, Ci will be named simply C. This equation is also referred to as Fick second law while Fick first law states the proportionality between mass flux and concentration gradient ( J Dd0Ci ). Although eq.(4.138) is the result of drastic simplifications that rar ...
... where, from for the sake of simplicity, Ci will be named simply C. This equation is also referred to as Fick second law while Fick first law states the proportionality between mass flux and concentration gradient ( J Dd0Ci ). Although eq.(4.138) is the result of drastic simplifications that rar ...
praceoryginalne - Wydawnictwo Naukowe UMP
... This specifically neglects edge effects, and also any changes in dimension for the specimen, for example swelling caused by uptake of water. In both cases, these approximations seem acceptable, and the system obeys this mathematical form. Release can therefore confidently be classified as a diffusio ...
... This specifically neglects edge effects, and also any changes in dimension for the specimen, for example swelling caused by uptake of water. In both cases, these approximations seem acceptable, and the system obeys this mathematical form. Release can therefore confidently be classified as a diffusio ...
CMS Issues Final Rule to Implement Medicaid Drug Pricing and
... CMS, because these programs do not purchase drugs directly but instead reimburse for drugs purchased from entities in the distribution chain, which will usually be in the retail pharmacy class of trade. But sales made through the retail class of trade and reimbursed by these programs are included in ...
... CMS, because these programs do not purchase drugs directly but instead reimburse for drugs purchased from entities in the distribution chain, which will usually be in the retail pharmacy class of trade. But sales made through the retail class of trade and reimbursed by these programs are included in ...
this PDF file - Acta Médica Portuguesa
... lt was a controlled study as weli. The main differences in relation to the procaina mide trial were that patients were of the classes 1 and II of Killip and Kimball, with no contraindication to beta-biockers, and there was no crossing-over: we only had a compa rison group of patients under the actio ...
... lt was a controlled study as weli. The main differences in relation to the procaina mide trial were that patients were of the classes 1 and II of Killip and Kimball, with no contraindication to beta-biockers, and there was no crossing-over: we only had a compa rison group of patients under the actio ...
HIPAA: Research Applications
... of off-label promotion in lawsuits (e.g., ParkeDavis) Is distribution of reprints “promotion” of off-label uses in violation of criterion #5? #5. The studies will not be used to promote unapproved indications, in compliance with 21 ...
... of off-label promotion in lawsuits (e.g., ParkeDavis) Is distribution of reprints “promotion” of off-label uses in violation of criterion #5? #5. The studies will not be used to promote unapproved indications, in compliance with 21 ...
Endogenous morphine-like compound immunoreactivity increases
... Morphine is endogenously synthesized in the central nervous system and endogenous dopamine is thought to be necessary for endogenous morphine formation. As Parkinson’s disease results from the loss of dopamine and is associated with central pain, we considered how endogenous morphine is regulated in ...
... Morphine is endogenously synthesized in the central nervous system and endogenous dopamine is thought to be necessary for endogenous morphine formation. As Parkinson’s disease results from the loss of dopamine and is associated with central pain, we considered how endogenous morphine is regulated in ...
Functional protein micropatterning for drug design
... drug discovery providing versatile means for high throughput assays required for target and lead identification as well as diagnostics and functional screening for personalized medicine. However, ensuring the functional integrity of proteins on surfaces has remained challenging, in particular in the ...
... drug discovery providing versatile means for high throughput assays required for target and lead identification as well as diagnostics and functional screening for personalized medicine. However, ensuring the functional integrity of proteins on surfaces has remained challenging, in particular in the ...