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Multi-Scale Modeling of the Primary Visual Cortex
Multi-Scale Modeling of the Primary Visual Cortex

... Figure 4: (a) Preferred cortical state of the neuron in the middle of the plot. (b) Spike-triggered activity pattern of the same neuron. (c) Evolution of the similarity index over time and orientation preference. (d) Evolution of the similarity index over time for orientation preference −60 deg. (e ...
Microcircuits in visual cortex Kevan AC Martin
Microcircuits in visual cortex Kevan AC Martin

... preferences change rapidly. Such images have been the inspiration for models of cortical wiring, where the goal is to discover whether the maps are in some way optimal solutions to the constraint of reducing wiring length [5,6•]. The significance of exploring this domain is that it places important ...
THE NEUROLOGIC EXAMINATION Ralph F
THE NEUROLOGIC EXAMINATION Ralph F

... The thalamus can be understood by considering a classification based upon function, and it can be understood by appreciating different types of output to the cerebral cortex. It is customary, however, to study the thalamus from an anatomical perspective. Each hemisphere of the thalamus consists of n ...
Developmental mechanics of the primate cerebral cortex
Developmental mechanics of the primate cerebral cortex

... help of deformed rubber tubes, and explained the cerebral shape by unequal growth, competing volume demands, and resulting tension of different brain structures (His 1874). The work of His and fellow embryologists inaugurated the subject of ‘developmental mechanics’ (Entwicklungsmechanik), which emph ...
Weisstaub cortical serotonin signaling modulates anxiety in mice science 2005
Weisstaub cortical serotonin signaling modulates anxiety in mice science 2005

... depression-related behaviors. Selective restoration of 5HT2AR signaling to the cortex normalized conflict anxiety behaviors. These findings indicate a specific role for cortical 5HT2AR function in the modulation of conflict anxiety, consistent with models of cortical, ‘‘top-down’’ influences on risk ...
Document
Document

... a clap in a single dream concurred with Galen’s prescient theory that one pneuma acts for each sense organ. This dream suggests an association of two sensory inputs or crossmodal processing: the ability to use one sense–vision–to learn something in another sense–sound. ...
HYPOTHALAMUS and EPITHALAMUS
HYPOTHALAMUS and EPITHALAMUS

... HYPOTHALAMUS and EPITHALAMUS Aim: To provide a structural basis for understanding the neural control of the 'milieu interne' via the autonomic & endocrine systems, and associated somatic behaviour; of the biological clock; reproductive functions; sleep-wake cycle, control of appetite, growth & metab ...
video slide - Course Notes
video slide - Course Notes

... • The hypothalamus also regulates circadian rhythms such as the sleep/wake cycle. • Mammals usually have a pair of suprachiasmatic nuclei (SCN) in the hypothalamus that function as a biological clock. • Biological clocks usually require external cues to remain synchronized with environmental cycles. ...
Rabies (Rhabdovirus)
Rabies (Rhabdovirus)

... Figure 2. Lateral view of brain with cerebrum removed to show the extension of brain stem beneath the cerebellum. A rabies diagnosis should include an observation of the cut surface of a cross section of the brain stem (through the medulla, pons, or midbrain area) and the cerebellum (through each h ...
030909.PHitchcock.IntroductoryLecture
030909.PHitchcock.IntroductoryLecture

... other neurons via their axons (also called fibers) and their synapses. • A collection of neuronal cell bodies outside the CNS is called a ganglion. • A collection of neuronal cell bodies within the CNS is called a nucleus. • A discrete bundle of axons outside the CNS is known as a nerve. • A discret ...
nightmares without atonia as an early symptom of diffuse lewy
nightmares without atonia as an early symptom of diffuse lewy

... plaques. Immunohistochemical staining for antibodies against tau, and β-amyloid were tested negative. There were also important release of lipofuscin and anoxia signs in the great pyramidal neurons. No focal white matter lesions or vascular disease were observed. Definitive diagnostic was diffuse Le ...
The Premotor Cortex and Mirror Neurons
The Premotor Cortex and Mirror Neurons

... Furthermore, when monkeys had to perform more complex actions the activity of grasping neurons was modulated since its early phases, suggesting that this activity could depend from a neural mechanism, probably located in the prefrontal cortex, that allows one to select actions on the basis of the co ...
emg and ncs: a practical approach to
emg and ncs: a practical approach to

... – Upper and lower limb motor studies (median, ulnar, radial and tibial and peroneal) • Less commonly, musculocutaneous and axillary studies ...
Human Anatomy & Physiology I
Human Anatomy & Physiology I

... Compares actual movements with intended ones Helps produce smooth, coordinated movements Helps execute skilled motor activities Regulates posture and balance ...
Growth arrest specific gene 7 is associated with schizophrenia and
Growth arrest specific gene 7 is associated with schizophrenia and

... Background: Schizophrenia is a highly heritable chronic mental disorder with significant abnormalities in brain function. The neurodevelopmental hypothesis proposes that schizophrenia originates in the prenatal period due to impairments in neuronal developmental processes such as migration and arbor ...
Human Vision: Electrophysiology and Psychophysics
Human Vision: Electrophysiology and Psychophysics

... At one time there was a debate as to the question of whether the brain was composed of a continuous system of wires or whether it was a discontinuous network made up of individual neurons ...
ling411-11 - Rice University
ling411-11 - Rice University

...  Regular and irregular inflections Syntax Semantics ...
Chapter 02 - Neurons and Glia
Chapter 02 - Neurons and Glia

... 20. Explain that neuroscientists have devised various schemes for the classification of neurons. Discuss the advantages of classifying neurons. In addition, explain the classification that is based on the number of neurites. (Refer to PowerPoint slide 23.) Teaching Suggestion: Using Figure 2.22, dis ...
Malformations of Cortical Development (MCD): Genetic Aspects
Malformations of Cortical Development (MCD): Genetic Aspects

... cortical development (MCD), which may be restricted to discrete cortical areas or may, alternatively, be diffuse [2, 3]. So far, more than 100 genes are reported to be associated with one or more types of MCD. The biological pathways include cell-cycle regulation at many steps (especially mitosis an ...
PREFRONTAL AND MEDIAL TEMPORAL LOBE INTERACTIONS IN
PREFRONTAL AND MEDIAL TEMPORAL LOBE INTERACTIONS IN

... neurons that show diminished responses to repeated stimuli25,26, whereas few such neurons have been found in the hippocampus27,28. The perirhinal cortex might have a role in perceptual as well as mnemonic processing, with evidence that complex feature conjunctions might be represented in this region ...
(2003). Prefrontal and medial temporal lobe interactions in
(2003). Prefrontal and medial temporal lobe interactions in

... neurons that show diminished responses to repeated stimuli25,26, whereas few such neurons have been found in the hippocampus27,28. The perirhinal cortex might have a role in perceptual as well as mnemonic processing, with evidence that complex feature conjunctions might be represented in this region ...
Genome wide expression profiling of the
Genome wide expression profiling of the

... Mesodiencephalic dopaminergic (mdDA) neurons comprising the substantia nigra (SN) and ventral tegmental area (VTA) are known to be crucial for diverse yet essential brain functions, such as associative motor learning, emotion and reinforcement (Berke and Hyman, 2000). Moreover, dysfunction of the md ...
Treatment of Thalamic Pain by Chronic Motor Cortex Stimulation
Treatment of Thalamic Pain by Chronic Motor Cortex Stimulation

... control in only 20%-30% of cases of thalamic pain syndrome. In order to deveJop a more effective treatment for thaJamic pain syndrome, we investigated the effects of stimulation of various brain regions on the burst hyperactivity 0/thaJamic neurons recorded in cats after deafferentiation of the spin ...
Hypothalamus
Hypothalamus

... Vent. posterolateral nucleus (VPL) ...
Feedforward, horizontal, and feedback processing
Feedforward, horizontal, and feedback processing

... In the past, V1 was mainly viewed as a static bank of spatio-temporal filters, preprocessing the visual input for the higher visual areas, in which perceptually relevant information was supposed to be extracted. However, it has long been known that responses of V1 cells can be altered by stimuli in ...
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Aging brain

Age is a major risk factor for most common neurodegenerative diseases, including Mild cognitive impairment, Alzheimer's disease, cerebrovascular disease, Parkinson's disease and Lou Gehrig's disease. While much research has focused on diseases of aging, there are few informative studies on the molecular biology of the aging brain (usually spelled ageing brain in British English) in the absence of neurodegenerative disease or the neuropsychological profile of healthy older adults. However, research does suggest that the aging process is associated with several structural, chemical, and functional changes in the brain as well as a host of neurocognitive changes. Recent reports in model organisms suggest that as organisms age, there are distinct changes in the expression of genes at the single neuron level. This page is devoted to reviewing the changes associated with healthy aging.
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