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Powerpoint slides
Powerpoint slides

... 1. Modern introns envaded eukaryotes late in evolution, they are derived from self-splicing mobile genetic elements similar to group II introns. 2. Nucleus which separates transcription and translation, appears only in eukaryotes. For prokaryotes there would not be time for introns to splice themsel ...
Chapter 7 Manipulating Proteins, DNA, and RNA
Chapter 7 Manipulating Proteins, DNA, and RNA

... The gene defective in mutant A acts before the gene defective in mutant B in the secretory pathway ...
DNA to Protein Synthesis
DNA to Protein Synthesis

... DNA must be copied to messenger RNA (mRNA) mRNA goes from nucleus to the ribosomes in cytoplasm mRNA complements known as codons ...
Chapt 11
Chapt 11

...  In eukaryotes, activator proteins seem to be more important than repressors. Thus, the default state for most genes seems to be off.  A typical plant or animal cell needs to turn on and transcribe only a small percentage of its genes. © 2012 Pearson Education, Inc. ...
Class: AP Bio Unit: Genetics Estimated Date Target Reading
Class: AP Bio Unit: Genetics Estimated Date Target Reading

... require use of the rule of multiplication and two probability questions that require use of the rule of addition.) Describe non-mendelian inheritance and human genetic disorders. ...
Slide 1
Slide 1

... • Requires mRNA to finish protein production mRNA: messenger RNA RNAi: RNA interference • Suppresses gene expression • Affects mRNA ...
Information flow within the cell
Information flow within the cell

... A few more complications… ...
Lecture Powerpoint Here
Lecture Powerpoint Here

... on a DNA region according to basepairing rules • As in DNA, C-G, but A-T does not exist • Uracil (U) pairs with adenine (A) ...
Making RNA in other ways
Making RNA in other ways

... oncogene that is a mutant copy of a normal cellular gene • There is no advantage for a virus to kill its host, however there is an advantage for the virus to force unregulated cell division – Cancer death may result from infection, but the host will live a relatively long time producing virus – When ...
Powerpoint Presentation: The Gene
Powerpoint Presentation: The Gene

... mRNA molecules are translated into polypeptides but… not all RNA is mRNA, genes are also transcribed into tRNA molecules and rRNA molecules tRNA and rRNA is not translated (though they are used in the translation process) So a gene is does not necessarily correspond to a polypeptide at all ...
Macro-Microarray
Macro-Microarray

... Construct a simple model of a DNA microarray and learn how they can be used to identify and treat disease. Materials and Preparation For each microarray: 6 screws or bolts that are each unique in size peg board or small board with holes drilled masking tape to label the screws For the “cDNA” samples ...
Carlson - Karola Stotz
Carlson - Karola Stotz

... irreversibility in evolution by Muller and other faculty in the department and eventually gave that talk with one of the worst cases of stage fright I experienced. I was talking to Cleland, Sonneborn, Kinsey, Heiser, and other top biologists and my graduate student peers and superiors. Fortunately, ...
Connective Tissue Disorders gene list
Connective Tissue Disorders gene list

... Postnatal Testing ...
English Version Full Professor of General Botany at Sapienza
English Version Full Professor of General Botany at Sapienza

... same University. Chief of the laboratory of "in vitro morphogenesis and differentiation" in the Department of Plant Biology of Sapienza University since 1987. Specific experience in cytology, histology, in vitro culture systems, electron and confocal microscopy, flow cytometry, epifluorescence. Spec ...
7 - Nature
7 - Nature

... Supplementary Figure 1. Bioinformatic assessment of miR-22 as a potential tumor suppressor gene. (a) Location of miR-22 in a minimal LOH (loss of heterozygosity) region at 17p13.3 between markers D17S1866 and D17S1574 in cancers. (b) Genomic organization of the human miR-22 locus. (c) RNA editing of ...
DNA Similarities
DNA Similarities

... Suppose you could compare the total DNA sequences of various organisms (some billions of base pairs). How much similarity would you expect between a whale and a fish? A whale and a dog? A dog and a shrimp? A shrimp and a bacterium? As always, there are two types of similarity to be considered: analo ...
Gene Expression Changes and Micro RNA Regulation in Embryonic
Gene Expression Changes and Micro RNA Regulation in Embryonic

... • Genes expressed by hESCs are involved with DNA replication, recombination and repair, RNA damage, and repair RNA posttranscriptional modification, cellular growth and proliferation, and cell cycle • ESC express several transcription factors including Oct4, Sox2, and nanog • Genes in several signal ...
Gene Expression
Gene Expression

... • Many copies of mRNA can be made from one gene • Many ribosomes can make protein from the same mRNA • Amplification of information allows rapid production of proteins ...
Recombinant DNA Technology
Recombinant DNA Technology

... o Can handle larger DNA inserts than plasmids  We can also tweak the plasmids to ensure expression of the new gene Cloning genes in eukaryotes  Yeast artificial chromosomes (YACs) contain a yeast origin of replication, a pair of telomeres, and a centromere o These can carry inserted DNA fragments ...
Mutation
Mutation

... Mutations affect the organisms phenotype, depending on the location of the change. Overview There are many ways (mechanisms) by which genetic change can occur. Mutation is a catch-all category for any form of change in DNA sequence. The textbook has subdivided mechanisms of DNA change into 4 broad c ...
No Slide Title
No Slide Title

... Transfer RNA (tRNA) leaves the nucleus, binds to the amino acid specified by it’s anticodon and transfers it to the ribisome where it meets up with mRNA to assemble a protein. ...
Structure/function relationship in DNA
Structure/function relationship in DNA

... RNA polymerase recognition of DNA during transcription involves a promoter region and a multi-subunit complex (machine) to conduct a complex process (unwinding DNA, RNA elongation, accurate translation of DNA via proofreading) Numerous proteins involved in regulation of transcription ...
Mutation and Recombination
Mutation and Recombination

... We will be attempting to induce a mutation in the lab today using UV light (Caution - the UV can also mutate your own DNA. Do not expose your skin or eyes to direct UV radiation!). UV radiation causes dimerization of adjacent thymine dimers in the DNA. It also causes the hydration of cytosines. As a ...
Text S1.
Text S1.

... DNA, termed G- and T-segments (representing Gate and Transfer). The G-segment contains the transient gap generated by the enzyme for the passage of T-segment. For the reaction to occur, the two segments should come close each other, which is easily achieved in circular DNAs with superhelical turns. ...
7.3 Protein Synthesis
7.3 Protein Synthesis

... P-site and bonds by base pairing its anti-codon with the mRNA start codon (what is the start codon?) • Elongation – The second tRNA then comes into A-site and bonds to codon of mRNA – The two amino acids joined with peptide bond • Termination – ribosome continues reading mRNA until a STOP codon is r ...
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Promoter (genetics)



In genetics, a promoter is a region of DNA that initiates transcription of a particular gene. Promoters are located near the transcription start sites of genes, on the same strand and upstream on the DNA (towards the 5' region of the sense strand).Promoters can be about 100–1000 base pairs long.
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