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CH. 13 - Weebly
CH. 13 - Weebly

... • Template: ...
ATPase Synthase Goes 100% Efficiency
ATPase Synthase Goes 100% Efficiency

... sequence occurs at what is called the branch point, located anywhere from 18 to 40 nucleotides upstream from the 3′ end of an intron. The branch point always contains an adenine, but it is otherwise loosely conserved…. Splicing occurs in several steps and is catalyzed by small nuclear ribonucleoprot ...
Biology Organic Molecules Notes
Biology Organic Molecules Notes

... V. Molecules of Life B.) Proteins 1.) Made of mostly C, H, O, and N 2.) Are long chains of amino acids  Joined together by peptide bonds  Dipeptide: two amino acids  Polypeptide: very long chain of amino acids  Proteins all have a different shape but are all globular ...
simulating protein analysis using gel electrophoresis
simulating protein analysis using gel electrophoresis

... A technique known as gel electrophoresis is widely used to analyze the size of macromolecules. These size differences can be used for evolutionary analysis as well as the analysis of a number of other critical questions regarding both proteins and DNA. Gel electrophoresis works on two relatively sim ...
DNA vs. RNA - Houston ISD
DNA vs. RNA - Houston ISD

... – Cut out of RNA molecules while still in the nucleus ...


... sigma subunit and unwinds short stretch of DNA. b) Sigma subunit released and transcription begins past promoter site. Termination: a) rho-independent: rich G-C dyad region followed by series of A’s and U’s (6-8) on RNA transcript causes formation of hairpin structure and consequently causes RNA pol ...
Protein Synthesis DNA vs. RNA
Protein Synthesis DNA vs. RNA

... – Cut out of RNA molecules while still in the nucleus ...
ppt link
ppt link

...  Serves as recognition site for ribosomes  Transports hnRNA from nucleus to cytoplasm ...
Transcription and Translation
Transcription and Translation

... • mRNA – carries the code from DNA to Ribosome • rRNA – makes up the Ribosomes (site of protein production) • tRNA – carries the amino acids to the ribosomes to be made into proteins • Most biology classes focus on the production of mRNA in the nucleus for transcription. ...
A CAAT–Box Binding Factor Gene That Regulates Seed Development
A CAAT–Box Binding Factor Gene That Regulates Seed Development

... - The CCAAT box is one of the most wide spread promoter elements, being present in 25% of eukaryotic promoters - to date, the one protein that binds and activates the CCAAT box is nuclear factor Y (NF-Y), a trimer composed of distinct subunits: NF-YA, NF-YB and NF-YC. NF-YB-NF-YC belong to the class ...
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GPI Anchor

... control gene expression and can act combinatorially to enforce or reverse epigenetic marks in chromatin. 4. Through their recognition by protein complexes with enzymatic activities, cross talk is established between different modifications and with other epigenetic pathways, including noncoding RNAs ...
RNA and Protein Synthesis (pp 300 – 306)
RNA and Protein Synthesis (pp 300 – 306)

... • There is one codon AUG that can either specify the amino acid methionine or serve as a “start” codon for protein synthesis • There are three “stop” codons that do not code for any amino acids • These “stop” codons signify the end of a polypeptide ...
Ch. 10: Presentation Slides
Ch. 10: Presentation Slides

... RNA Transcription: Splicing • Spliceosomes contain protein and specialized small RNAs complementary to the splice junctions to provide specificity to splicing reaction • Small nuclear RNAs U1, U2 and U5 recognize splice donor and acceptor sites by complementary base pairing so that intron excision ...
ProteinShop: A tool for protein structure prediction and modeling
ProteinShop: A tool for protein structure prediction and modeling

... To determine how proteins, the building blocks of living cells, fold themselves into three-dimensional shapes that define the role they play in life. ...
Chapter 13 RNA and Protein Synthesis
Chapter 13 RNA and Protein Synthesis

...  ____________ are regions of DNA that signal the RNA polymerase where to begin making the RNA strand  mRNA often needs to be edited so the portions cut out are called _______ and the portions spliced together are call ________. 13.2 Ribosomes and Protein Synthesis The Genetic Code  The code carri ...
UC Irvine FOCUS! 5 E Lesson Plan Title: Genetics Scavenger Hunt
UC Irvine FOCUS! 5 E Lesson Plan Title: Genetics Scavenger Hunt

... of DNA is transferred to a newly assembled piece of mRNA. It is facilitated by RNA polymerase and transcription factors Splicing: In eukaryote cells the primary transcript (pre-mRNA) is processed. One or more sequences (Introns) are cut out. The mechanism of alternative splicing makes it possible to ...
DNA structure
DNA structure

... • Transcription (same language) in nucleus • Translation (new language) in cytoplasm – mRNA codes for polypeptides ...
3. Protein Structure and Function – Bio 20-1
3. Protein Structure and Function – Bio 20-1

... ▫ Side chains with –COOH ▫ Predominantly in unprotonated form ...
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Nuclear gene expression 1

... Can also be shown for cellular genes by DNase I digestion of chromatin – promoter regions are hypersensitive to DNase I. Fig. 13.25 ...
Proteins
Proteins

... Denaturation is when the bonds of the protein are broken causing it to uncoil or form a new shape. This is caused by heat, pH, or radiation. This change is not permanent Coagulation is a permanent change in the structure. Example is a boiled egg ...
DNA - wwphs
DNA - wwphs

... • The genetic information encoded in the DNA of an embryo includes all of the genes needed to develop and maintain the organism. • Different cell types express different subsets of genes. • Differential gene expression during development establishes the role of a cell within the body. ...
Gene Section RBM15 (RNA binding motif protein 15) in Oncology and Haematology
Gene Section RBM15 (RNA binding motif protein 15) in Oncology and Haematology

... 5' OTT - 3' MAL, comprisng most of OTT fused to most of MAL; the reciprocal 5' MAL - 3' OTT may or may not be present. Abnormal protein Includes most of OTT with the RNA recognition motifs and the SPOC domain in N-term, and most of MAL, with the scaffold attachment factor box in C-term. Oncogenesis ...
Protein Structure
Protein Structure

... as C-term AA Eg. Chymotrypsin: cleave to leave Tyr or Trp or Phe as C-term AA Eg. Cyanogen bromide cleaves at internal Met leaving Met as C-term ...
Section 12-3 RNA and Protein Synthesis
Section 12-3 RNA and Protein Synthesis

... a. Before translation occurs, messenger RNA is transcribed from DNA in the nucleus. b. Translation occurs in the nucleus. c. It is the job of transfer RNA to bring the proper amino acid into the ribosome to be attached to the growing peptide chain. d. When the ribosome reaches a stop codon, it relea ...
What are proteins?
What are proteins?

... observed in liver and heart show that proteins in heart turn over more slowly than in the liver. • Mitochondria in the heart and those in the liver ...
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SR protein



SR proteins are a conserved family of proteins involved in RNA splicing. SR proteins are named because they contain a protein domain with long repeats of serine and arginine amino acid residues, whose standard abbreviations are ""S"" and ""R"" respectively. SR proteins are 50-300 amino acids in length and composed of two domains, the RNA recognition motif (RRM) region and the RS binding domain. SR proteins are more commonly found in the nucleus than the cytoplasm, but several SR proteins are known to shuttle between the nucleus and the cytoplasm.SR proteins were discovered in the 1990s in Drosophila and in amphibian oocytes, and later in humans. In general, metazoans appear to have SR proteins and unicellular organisms lack SR proteins.SR proteins are important in constitutive and alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA by preferentially selecting different splice sites on the pre-mRNA strands to create multiple mRNA transcripts from one pre-mRNA transcript. Once splicing is complete the SR protein may or may not remain attached to help shuttle the mRNA strand out of the nucleus. As RNA Polymerase II is transcribing DNA into RNA, SR proteins attach to newly made pre-mRNA to prevent the pre-mRNA from binding to the coding DNA strand to increase genome stabilization. Topoisomerase I and SR proteins also interact to increase genome stabilization. SR proteins can control the concentrations of specific mRNA that is successfully translated into protein by selecting for nonsense-mediated decay codons during alternative splicing. SR proteins can alternatively splice NMD codons into its own mRNA transcript to auto-regulate the concentration of SR proteins. Through the mTOR pathway and interactions with polyribosomes, SR proteins can increase translation of mRNA.Ataxia telangiectasia, neurofibromatosis type 1, several cancers, HIV-1, and spinal muscular atrophy have all been linked to alternative splicing by SR proteins.
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