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VHF Review - Case Western Reserve University
VHF Review - Case Western Reserve University

... and tissues can directly contribute to the pathological manifestations of VHF. Factors that may contribute to this subversion of the host immune response include the rapid infection and impairment of dendritic cells, a sudden and enigmatic death of lymphocytes, and the release of a variety of mediat ...
Chicken pox - Healthwise
Chicken pox - Healthwise

... The rash, which is commonly the first sign of infection in children passes through four stages, from reddish spots flush with the skin surface, to raised papules, to small blisters filled with clear fluid (the vesicles), and, lastly, to pustules which crust over and heal. But the first thing most pa ...
Quarantine and Isolation During the Sedgwick County Measles
Quarantine and Isolation During the Sedgwick County Measles

... *The average number of secondary cases generated by a primary case at the onset of an epidemic in an entirely ...
Hepatitis A and Norovirus - Food Science and Human Nutrition
Hepatitis A and Norovirus - Food Science and Human Nutrition

... – GI, GII, and GIV are in human – GIII and GV are in cows and mice – GII are in pigs and GIV in dogs • Zoonotic transmission is the key – No cases of calf to human or pig to human transmission have been found ...
Surveillance of viral fish diseases in the Czech Republic over the
Surveillance of viral fish diseases in the Czech Republic over the

... (Table 2). Positive samples included tissue homogenates as well as ovarian fluids. The virus was isolated only once during the routine surveillance. The remaining positive cases were derived from diseased fish, despite the fact that the number of diagnostic samples was nearly 10 times lower than the ...
Effector cytotoxic T lymphocyte numbers induced
Effector cytotoxic T lymphocyte numbers induced

... To calculate this threshold we used the notion of basic reproductive number (R0 ) [28], the number of cells infected by a single cell in a susceptible cell population (see Appendix A). If R0 of the infecting virus is smaller than 1, the infection cannot spread within an individual [29]. In the chron ...
The Arrow of Disease - Anthropologyman.com
The Arrow of Disease - Anthropologyman.com

... an untreated cholera patient may eventually die from produc_ ing diarrheal fluid at a rate of several gallons a day. While the patient lasts, though, the cholera bacterium profits from being massively disseminated into the water supplies of its next victims. As long as each victim thereby infects, o ...
A Review of Equine Zoonotic Diseases: Risks in Veterinary
A Review of Equine Zoonotic Diseases: Risks in Veterinary

... visible wounds does not preclude rabies.6 Further, a history of vaccination does not completely rule out the possibility of rabies, because one study reported that 5 of 21 affected horses had been previously vaccinated.6 Rabies can be excluded early in most cases based on results of other diagnostic ...
Severe Acute Respiratory Syndrome (SARS)
Severe Acute Respiratory Syndrome (SARS)

... reality of infectious diseases like SARS in the community and in the health care system. Infection Control standards remain high as regular practice throughout the medical community. SARS would most likely re-emerge in Ontario by importing the virus from a foreign source. In other words, transmissio ...
Swine flu - infectious diseases content sampler
Swine flu - infectious diseases content sampler

... America report a series of 642 cases from United States identified by enhanced surveillance and confirmed by real-time RT-PCR, viral culture, or both. The most frequently reported symptoms in this series are fever (94%), cough (92%), and sore throat (66%); 25% of patients report diarrhoea, and a furth ...
Tissue Tropism and Pathobiology of Infectious Laryngotracheitis
Tissue Tropism and Pathobiology of Infectious Laryngotracheitis

... Conjunctivitis, swelling of the infraorbital sinuses and closed eyes noticed in this study correlated well with the earlier report of Guy and Bagust (10). These lesions probably were induced by the proliferation of ILTV in conjunctiva, which has been supported by the detection of ILTV in conjunctiva ...
Feline Infectious Peritonitis
Feline Infectious Peritonitis

... antibody. It is probably best not to vaccinate a “positive” cat. Unfortunately, there is nothing that can be done to affect the outcome. It depends on complex factors including genetics, the strain of Feline Coronavirus (most strains are relatively harmless), and so on. What are the first signs of F ...
sequential hematological study of experimental infectious bursal
sequential hematological study of experimental infectious bursal

... where an IBDV infection has been established. Indeed, the twophase lymphopenia in the chicks between 3 to 96 h pi helps to explain the pathogenesis of biphasic viremia in IBD described by Weiss and Kaufer-Weiss (15). The marked heterophilia observed in the chicks in this study is evidence of massive ...
Infection Control Guidelines for Community Shelters and Group
Infection Control Guidelines for Community Shelters and Group

... up”; instead, rinse them with hot water when empty then refill. Bar soap should be stored in racks which allow drainage of excess water (disease-producing organisms can survive in ...


... to the detection of these agents in poultry (Ali and Reynolds, 2000), while there remains a need for rapid screening of possibly differently introduced viruses that share the same reservoirs in the wild. A single step multiplexes RT-PCR for AI, ND and IBD viruses described in present work. Early det ...
CDC: Birth defect rate 20 times higher for infants with Zika
CDC: Birth defect rate 20 times higher for infants with Zika

... Infants whose mothers were infected with Zika virus had rates of birth defects that were 20-times higher than those born in the years just prior to the epidemic, according to a new study. The Centers for Disease Control and Prevention (CDC) found 6% of infants with an infected mother developed birth ...
Guidelines for Common Childhood Communicable Diseases
Guidelines for Common Childhood Communicable Diseases

... • Direct contact with respiratory secretions. • Indirect contact with toys, other objects or surfaces contaminated with respiratory secretions Fever, small painful blisters in the mouth, which make it difficult for the child to eat or drink. Blisters on the palms of child’s hands, on their fingers, ...
Rose virus and virus-like diseases
Rose virus and virus-like diseases

... The third virus-like disease of roses being st udi ed is tentatively called “rose X” (RX) disease. The disease has been found in commercially grown roses in California and Oregon and was discovered during routine screening of varieties for other diseases. No evidence of natural spread has been obser ...
Human West Nile virus infection in Bosnia and
Human West Nile virus infection in Bosnia and

... Nile virus was first identified in the West Nile district of Uganda in 1937 in a woman who presented with a mild febrile illness (3). During the next decades, the virus spread through Africa and Asia. It was first described in Europe in the 1960s when seropositive animals or virus isolates were repo ...
Sensitive populations: who is at the greatest risk?
Sensitive populations: who is at the greatest risk?

... advantage of their impaired or destroyed immune system to set up persistent and generalized infections in the immunocompromised host. Such infections are difficult to treat, tend to be long term, add to the burden of the debilitation in the patient, and can result in a significant higher mortality t ...
Rinderpest
Rinderpest

... The traditional ‘gold standard’ virus neutralisation (VN) test in roller-tube cultures of primary calf kidney cells has now been replaced by a microneutralisation test format test may be used to examine the sera of ELISA reactors during national serosurveillance programmes designed to demonstrate fr ...
PDF-354K - ScienceCentral
PDF-354K - ScienceCentral

... population of Aedes albopictus for Zika virus (ZIKV). Ae. albopictus was susceptible to ZIKV infection (infection rate: 10%), and the virus could disseminate and was secreted in the mosquito’s saliva (dissemination rate: 29%; transmission rate: 29%) after an extrinsic incubation period of 11 days. T ...
viral hemorrhagic fever
viral hemorrhagic fever

... • Contact with blood, secretions, or tissue of an infected animal • Inhalation of aerosols by laboratory workers during cultivation of these viruses • Ingestion of contaminated raw goat milk • Waterborne (suspected) • Airborne (suspected) ...
Microbial ecology of the lower genital tract in women with sexually
Microbial ecology of the lower genital tract in women with sexually

... HPV can infect and replicate in only the basal cells of stratified epithelium, which is accomplished through micro-abrasions or other epithelial trauma that exposes parts of the basement membrane (Schiller et al., 2010). Risk factors include sexually active women under 25 years of age (Table 3), a h ...
Adult Medical Surgical Nursing 1
Adult Medical Surgical Nursing 1

... Hepatitis A: (HAV)  RNA virus; spread by faecal-oral route (contaminated food, water, hands)  Short incubation (average 30 days)  Diagnosed by anti-HAV IgM in serum during an acute attack  Anti-HAV IgG in serum indicates previous infection or vaccination = now immune  Prevention: active immuni ...
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Ebola virus disease



Ebola virus disease (EVD; also Ebola hemorrhagic fever, or EHF), or simply Ebola, is a disease of humans and other primates caused by ebolaviruses. Signs and symptoms typically start between two days and three weeks after contracting the virus with a fever, sore throat, muscular pain, and headaches. Then, vomiting, diarrhea and rash usually follow, along with decreased function of the liver and kidneys. At this time some people begin to bleed both internally and externally. The disease has a high risk of death, killing between 25 and 90 percent of those infected, with an average of about 50 percent. This is often due to low blood pressure from fluid loss, and typically follows six to sixteen days after symptoms appear.The virus spreads by direct contact with body fluids, such as blood, of an infected human or other animals. This may also occur through contact with an item recently contaminated with bodily fluids. Spread of the disease through the air between primates, including humans, has not been documented in either laboratory or natural conditions. Semen or breast milk of a person after recovery from EVD may still carry the virus for several weeks to months. Fruit bats are believed to be the normal carrier in nature, able to spread the virus without being affected by it. Other diseases such as malaria, cholera, typhoid fever, meningitis and other viral hemorrhagic fevers may resemble EVD. Blood samples are tested for viral RNA, viral antibodies or for the virus itself to confirm the diagnosis.Control of outbreaks requires coordinated medical services, alongside a certain level of community engagement. The medical services include rapid detection of cases of disease, contact tracing of those who have come into contact with infected individuals, quick access to laboratory services, proper healthcare for those who are infected, and proper disposal of the dead through cremation or burial. Samples of body fluids and tissues from people with the disease should be handled with special caution. Prevention includes limiting the spread of disease from infected animals to humans. This may be done by handling potentially infected bush meat only while wearing protective clothing and by thoroughly cooking it before eating it. It also includes wearing proper protective clothing and washing hands when around a person with the disease. No specific treatment or vaccine for the virus is available, although a number of potential treatments are being studied. Supportive efforts, however, improve outcomes. This includes either oral rehydration therapy (drinking slightly sweetened and salty water) or giving intravenous fluids as well as treating symptoms.The disease was first identified in 1976 in two simultaneous outbreaks, one in Nzara, and the other in Yambuku, a village near the Ebola River from which the disease takes its name. EVD outbreaks occur intermittently in tropical regions of sub-Saharan Africa. Between 1976 and 2013, the World Health Organization reports a total of 24 outbreaks involving 1,716 cases. The largest outbreak is the ongoing epidemic in West Africa, still affecting Guinea and Sierra Leone. {{#section:Ebola virus epidemic in West Africa|casesasof}}, this outbreak has {{#section:Ebola virus epidemic in West Africa|cases}} reported cases resulting in {{#section:Ebola virus epidemic in West Africa|deaths}} deaths.{{#section:Ebola virus epidemic in West Africa|caserefs}}
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