Data Sheet Sorafenib Tosylate
... that inhibits cell proliferation by targeting receptor tyrosine kinases, including VEGFR-2 and PDGFR--β and their associated signaling cascades of the ERK pathway and angiogenesis. It was originally developed as a Raf kinase inhibitor. It has been shown to have activity against several receptor tyro ...
... that inhibits cell proliferation by targeting receptor tyrosine kinases, including VEGFR-2 and PDGFR--β and their associated signaling cascades of the ERK pathway and angiogenesis. It was originally developed as a Raf kinase inhibitor. It has been shown to have activity against several receptor tyro ...
kutki churna - International Journal of Research in Ayurveda and
... the present era of widely expanded commercialized pharma sector due to various factors like availability of the herbs, increasing pollution and deforestation, etc. Therefore it’s the need of the hour to focus our attention on the stability of Ayurvedic drugs. Churna Kalpana, the most commonly used A ...
... the present era of widely expanded commercialized pharma sector due to various factors like availability of the herbs, increasing pollution and deforestation, etc. Therefore it’s the need of the hour to focus our attention on the stability of Ayurvedic drugs. Churna Kalpana, the most commonly used A ...
SW_QA167_6Dosing_in_renal_impairmentFINAL
... may increase serum concentrations of the parent drug and consequent toxicity if the drug is metabolised to inactive metabolites (2). Many drugs and/or their phase I metabolites are eliminated by glucuronidation and the glucuronides are excreted by renal mechanisms. Therefore in patients with RI, glu ...
... may increase serum concentrations of the parent drug and consequent toxicity if the drug is metabolised to inactive metabolites (2). Many drugs and/or their phase I metabolites are eliminated by glucuronidation and the glucuronides are excreted by renal mechanisms. Therefore in patients with RI, glu ...
1._Poisoning
... • Urea, electrolytes, creatinine should be measured in most patients. • Arterial blood gases should be checked in those with significant respiratory or circulatory compromise, or when poisoning with substances likely to affect acid–base status is suspected. • Calculation of anion and osmolar gaps ma ...
... • Urea, electrolytes, creatinine should be measured in most patients. • Arterial blood gases should be checked in those with significant respiratory or circulatory compromise, or when poisoning with substances likely to affect acid–base status is suspected. • Calculation of anion and osmolar gaps ma ...
Algorithm for Treating Epilepsy Patients with Carbamazepine
... Before starting, check if patient is positive for HLA-B*1502, especially those patients whose ancestors are from Asia, including South Asian Indians. If positive, the patient is at increased risk for serious and potentially fatal rash and the risk-benefit ratio should be re-evaluated. See http://www ...
... Before starting, check if patient is positive for HLA-B*1502, especially those patients whose ancestors are from Asia, including South Asian Indians. If positive, the patient is at increased risk for serious and potentially fatal rash and the risk-benefit ratio should be re-evaluated. See http://www ...
5.5 Illicit drug use—current and future issues
... Box 5.2 for definitions). Illicit drug use is associated with conditions such as HIV/AIDS, hepatitis C, low birthweight, malnutrition, infective endocarditis (leading to damage to the heart valves), poisoning, mental illness, suicide, self-inflicted injury and overdose (AIHW 2010). The relative heal ...
... Box 5.2 for definitions). Illicit drug use is associated with conditions such as HIV/AIDS, hepatitis C, low birthweight, malnutrition, infective endocarditis (leading to damage to the heart valves), poisoning, mental illness, suicide, self-inflicted injury and overdose (AIHW 2010). The relative heal ...
CNS Antiparkinsonian Drugs
... Exact timing of medication – cannot be administered late Oral doses given with food Avoid foods in Vit B6 – reverse effects of levodopa Force fluids >2,000 mL/day High roughage, high fiber diet ...
... Exact timing of medication – cannot be administered late Oral doses given with food Avoid foods in Vit B6 – reverse effects of levodopa Force fluids >2,000 mL/day High roughage, high fiber diet ...
REGULATION ON REGISTRATION OF DRUGS
... drugs. Satisfying all conditions and standards required by the MoH. May applying for producing drugs. 3.2-Disease examination and treatment establishments and medical – pharmaceutical institutions which are not functioned to produce drugs (administrative units) are not subject to application of this ...
... drugs. Satisfying all conditions and standards required by the MoH. May applying for producing drugs. 3.2-Disease examination and treatment establishments and medical – pharmaceutical institutions which are not functioned to produce drugs (administrative units) are not subject to application of this ...
Discovering drug interactions: a text
... One of the challenges in drug administration and drug development is the need to identify and avoid potential drug-drug interactions. When several drugs are being administered, there is a possibility of adverse drug reactions as one drug can increase or decrease the effect of another drug. During th ...
... One of the challenges in drug administration and drug development is the need to identify and avoid potential drug-drug interactions. When several drugs are being administered, there is a possibility of adverse drug reactions as one drug can increase or decrease the effect of another drug. During th ...
Medications Requiring Prior Authorization for Medical
... liability whatsoever for the information provided or for any diagnosis or treatment made as a result of this information. This list is subject to change. Subject to applicable laws and regulations. ...
... liability whatsoever for the information provided or for any diagnosis or treatment made as a result of this information. This list is subject to change. Subject to applicable laws and regulations. ...
VETS 238 Surgical Nursing and Anesthesia
... cats: may show bizarre responses; i.e., excitement, anxiety ...
... cats: may show bizarre responses; i.e., excitement, anxiety ...
File opiates powerpoint (webpage)
... Oxycodone is the drug name of the opiate. It is also known as “OxyContin”. *OxyContin is highly addictive, and one of the strongest painkillers available! Usually taken orally in pill or tablet form. Can provide pain relief for up to 12 hours. OxyContin most commonly exists in tablet form. ...
... Oxycodone is the drug name of the opiate. It is also known as “OxyContin”. *OxyContin is highly addictive, and one of the strongest painkillers available! Usually taken orally in pill or tablet form. Can provide pain relief for up to 12 hours. OxyContin most commonly exists in tablet form. ...
lecture 9+10 - Antihypertensive (First Year)
... hypertension Verapamil is more effective as cardiac depressant , is not used as antihypertensive agent . Diltiazem .Used mainly for angina ...
... hypertension Verapamil is more effective as cardiac depressant , is not used as antihypertensive agent . Diltiazem .Used mainly for angina ...
ไม่มีชื่อเรื่องภาพนิ่ง
... tablet or capsule still remained for other drug products. This information is very important for product development since drugs have to dissolve from solid dosage forms prior to absorption. Further, content uniformity is another important test item to demonstrate the uniformity of dosage unit, part ...
... tablet or capsule still remained for other drug products. This information is very important for product development since drugs have to dissolve from solid dosage forms prior to absorption. Further, content uniformity is another important test item to demonstrate the uniformity of dosage unit, part ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... decades. Clinicians treating tuberculosis (TB) patients around the world know these medicines well, and are usually well aware of their associated adverse drug reactions (ADRs). The occurrence of these reactions is known to be frequent. The TB patient on treatment is taking more than one anti TB med ...
... decades. Clinicians treating tuberculosis (TB) patients around the world know these medicines well, and are usually well aware of their associated adverse drug reactions (ADRs). The occurrence of these reactions is known to be frequent. The TB patient on treatment is taking more than one anti TB med ...
Anti Hyperlipidaemic Agents
... bile acid reabsorption as high as ten folds. 2. ↑excretion of bile acid a. ↑cholesterol secretion b. ↓hepatic cholesterol level c. ↑uptake of LDL from circulation i. ↓plasma LDL ii. ↓plasma cholesterol level d. Compensatory mechanism of the loss of LDL will ↑VLDL and therefore ↑plasma TG level 3. It ...
... bile acid reabsorption as high as ten folds. 2. ↑excretion of bile acid a. ↑cholesterol secretion b. ↓hepatic cholesterol level c. ↑uptake of LDL from circulation i. ↓plasma LDL ii. ↓plasma cholesterol level d. Compensatory mechanism of the loss of LDL will ↑VLDL and therefore ↑plasma TG level 3. It ...
January / February 2016
... be eliminated by metabolic processes.1 For effective systemic delivery, a relatively high drug concentration must circulate in the plasma to achieve a therapeutic dose within the eye. Oral drugs can be suitable for posterior segment treatment, although this exposes the whole body to the drug, often ...
... be eliminated by metabolic processes.1 For effective systemic delivery, a relatively high drug concentration must circulate in the plasma to achieve a therapeutic dose within the eye. Oral drugs can be suitable for posterior segment treatment, although this exposes the whole body to the drug, often ...
Chapter 48 Antidysrhythmic Drugs
... smaller pieces, dislodge from the location where it was initially formed.) An embolus is a blood clot, piece/globule of fatty deposit, or other object that is carried through the bloodstream. An embolism refers to the obstruction of a blood vessel by a foreign substance or a blood clot that trav ...
... smaller pieces, dislodge from the location where it was initially formed.) An embolus is a blood clot, piece/globule of fatty deposit, or other object that is carried through the bloodstream. An embolism refers to the obstruction of a blood vessel by a foreign substance or a blood clot that trav ...
SOC 12 - hrsbstaff.ednet.ns.ca
... but by the time the movie opens, there is nothing in his life of any importance, really, but cocaine. He doesn't even question the fact. It's not that he needs cocaine to function - because he doesn't function, really; he just goes through the motions - but that he needs cocaine to still himself fro ...
... but by the time the movie opens, there is nothing in his life of any importance, really, but cocaine. He doesn't even question the fact. It's not that he needs cocaine to function - because he doesn't function, really; he just goes through the motions - but that he needs cocaine to still himself fro ...
to our crestor information package
... Crestor may cause rare, but serious, side effects including: Muscle damage. Crestor can cause serious muscle damage that can lead to kidney damage. The risk of muscle damage may be increased by taking certain drugs. Crestor should be used with caution if you have kidney problems, advanced age, and h ...
... Crestor may cause rare, but serious, side effects including: Muscle damage. Crestor can cause serious muscle damage that can lead to kidney damage. The risk of muscle damage may be increased by taking certain drugs. Crestor should be used with caution if you have kidney problems, advanced age, and h ...
Psychoactive plant species - Journal List
... DMT. Shamans of the Amazon performs healing ayahuasca rituals for their communities. They look after their patients during these events for proper execution of the process. Diarrhea and vomiting often occurs among different side effects, even after small doses of the plant. According to the local tr ...
... DMT. Shamans of the Amazon performs healing ayahuasca rituals for their communities. They look after their patients during these events for proper execution of the process. Diarrhea and vomiting often occurs among different side effects, even after small doses of the plant. According to the local tr ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.