SWOV Fact sheet Driving under the influence of drugs and
... differences in the effects even within a single type of drug. The effect of cannabis, for example, is that the user becomes ‘high’ or ‘stoned’ and experiences feelings of euphoria, relaxation and lethargy. Their reaction time increases, their coordination decreases, and their memory is affected. As ...
... differences in the effects even within a single type of drug. The effect of cannabis, for example, is that the user becomes ‘high’ or ‘stoned’ and experiences feelings of euphoria, relaxation and lethargy. Their reaction time increases, their coordination decreases, and their memory is affected. As ...
Full-Text - Tropical Journal of Pharmaceutical Research
... compared to other drugs in the same group such as chlorpheniramine or ebastine [5]. Details are shown in Table 1. As a result of a systematic world literature review on clemastine as an active substance, no new adverse reactions or new information have been found, which might adversely affect the ex ...
... compared to other drugs in the same group such as chlorpheniramine or ebastine [5]. Details are shown in Table 1. As a result of a systematic world literature review on clemastine as an active substance, no new adverse reactions or new information have been found, which might adversely affect the ex ...
Management of Parkinson`s Disease
... Patients often display a generalised lack of movement both in terms of facial expression and general body movement. They often have reduced arm swing (usually asymmetrical at the beginning) with festinate gait. They may have impaired ability to correct their balance. There is no treatment that has b ...
... Patients often display a generalised lack of movement both in terms of facial expression and general body movement. They often have reduced arm swing (usually asymmetrical at the beginning) with festinate gait. They may have impaired ability to correct their balance. There is no treatment that has b ...
Mebendazole
... – Currently, praziquantel is the most common drug used for the treatment of all species of schistosomes – The drug artemisinin, an antimalarial, is also effective against schistosomes ...
... – Currently, praziquantel is the most common drug used for the treatment of all species of schistosomes – The drug artemisinin, an antimalarial, is also effective against schistosomes ...
The treatment of hypertension IN THE ELDERLY
... In the elderly, therapy of hypertension demands care. Because of the variable sensitivity of target tissues and changes in the pharmacokinetic of drugs as results of physiological and pathological alterations in elderly, particular unwanted effects from drug therapy can develop. Tubular function dec ...
... In the elderly, therapy of hypertension demands care. Because of the variable sensitivity of target tissues and changes in the pharmacokinetic of drugs as results of physiological and pathological alterations in elderly, particular unwanted effects from drug therapy can develop. Tubular function dec ...
Cross Addictions and Safe Medications
... Safe Medications For sleep issues, try Bevitamel (melatonin), chamomile tea, Sleepytime tea, or ...
... Safe Medications For sleep issues, try Bevitamel (melatonin), chamomile tea, Sleepytime tea, or ...
Anti Epileptic Drugs
... 10. What are the disadvantages ? • Moderately high cost • May render hormonal contraceptive ineffective • May increase plasma level of Phenytoin and Phenobarbitone and these drugs may decrease oxcarbazepine level ...
... 10. What are the disadvantages ? • Moderately high cost • May render hormonal contraceptive ineffective • May increase plasma level of Phenytoin and Phenobarbitone and these drugs may decrease oxcarbazepine level ...
Levsin SL PI RA - Meda Pharmaceuticals
... Reported clinical experience has not identified differences in safety between patients aged 65 and over and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepat ...
... Reported clinical experience has not identified differences in safety between patients aged 65 and over and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepat ...
Lecture 21
... Interpret results of disk-diffusion method. Identify the methods of action and preferred uses of chemical disinfectants. Identify the appropriate uses for surface-active agents. Identify the method of sterilizing plastic lab ware. Explain how microbial control is affected by the type of microbe. ...
... Interpret results of disk-diffusion method. Identify the methods of action and preferred uses of chemical disinfectants. Identify the appropriate uses for surface-active agents. Identify the method of sterilizing plastic lab ware. Explain how microbial control is affected by the type of microbe. ...
汤慧芳_抗疟药
... – highly effective for both the treatment and chemoprophylaxis of falciparum malaria（恶性疟疾）, and it is now approved for both indications in the USA. – For chemoprophylaxis, Malarone must be taken daily. It has an advantage over mefloquine and doxycycline in requiring shorter periods of treatment befo ...
... – highly effective for both the treatment and chemoprophylaxis of falciparum malaria（恶性疟疾）, and it is now approved for both indications in the USA. – For chemoprophylaxis, Malarone must be taken daily. It has an advantage over mefloquine and doxycycline in requiring shorter periods of treatment befo ...
Iraqi pharmacovigilance (center(IQPHVC
... The new recommended dose in adults (and adolescents ≥ 35 kg where licensed) is 10 mg orally up to three times daily (maximum dose of 30 mg daily). Adults may also be given 30 mg twice daily rectally as suppositories. Where suitable domperidone products are available for children, the recommended dos ...
... The new recommended dose in adults (and adolescents ≥ 35 kg where licensed) is 10 mg orally up to three times daily (maximum dose of 30 mg daily). Adults may also be given 30 mg twice daily rectally as suppositories. Where suitable domperidone products are available for children, the recommended dos ...
Antiinfective drugs Chemotherapy: is the treatment of a disease by
... Mechanisms underlying microbial resistance to cell wall synthesis inhibitors include the production of antibiotic-inactivating enzyme, changes in the structure of target receptors, increased efflux via drug transporters, ...
... Mechanisms underlying microbial resistance to cell wall synthesis inhibitors include the production of antibiotic-inactivating enzyme, changes in the structure of target receptors, increased efflux via drug transporters, ...
1100_Jacob Koruth - New Cardiovascular Horizons
... • 1518 patients with class III and IV CHF, EF<35% • No difference in total mortality, cardiovascular ...
... • 1518 patients with class III and IV CHF, EF<35% • No difference in total mortality, cardiovascular ...
Antiparasitic Agents
... Pentamidine was originally developed as an antitrypanosomal drug. It is the safest of the diamidine group of antiprotozoals although it still has significant toxicity. The mechanism is unclear, but in trypanosomes it appears to bind to DNA. II. USES a.) Treatment and prophylaxis (aerosolized form) o ...
... Pentamidine was originally developed as an antitrypanosomal drug. It is the safest of the diamidine group of antiprotozoals although it still has significant toxicity. The mechanism is unclear, but in trypanosomes it appears to bind to DNA. II. USES a.) Treatment and prophylaxis (aerosolized form) o ...
2-Ocular pharmacology and toxicology
... • Acute, painful increases of pressure due to occlusion of the outflow drainage pathway • emergency situation that require treatment before surgery (Iridectomy) The use of drugs is limited to : • Oral Acetazolamide • Topical cholinomimetics e.g.: pilocarpine • Osmotic agents: hypertonic solution( Ma ...
... • Acute, painful increases of pressure due to occlusion of the outflow drainage pathway • emergency situation that require treatment before surgery (Iridectomy) The use of drugs is limited to : • Oral Acetazolamide • Topical cholinomimetics e.g.: pilocarpine • Osmotic agents: hypertonic solution( Ma ...
Volume 6 Number 18 (Issue 195) Tuesday, Jul yy 22,, 2008 NEW
... taking fluoroquinolones for systemic use. This risk of tendinitis and tendon rupture is further increased in those over age 60, in kidney, heart, and lung transplant recipients, and with use of concomitant steroid therapy. Physicians should advise patients, at the first sign of tendon pain, swelling ...
... taking fluoroquinolones for systemic use. This risk of tendinitis and tendon rupture is further increased in those over age 60, in kidney, heart, and lung transplant recipients, and with use of concomitant steroid therapy. Physicians should advise patients, at the first sign of tendon pain, swelling ...
anesthetic agents - hsvma-ravs
... May be less likely to cause tachycardia and cardiac arrhythmias than atropine Can cause an initial paradoxical bradycardia and AV block when given IV. This effect is usually overcome as plasma levels become therapeutic Note: Hypothermia results in decreased depolarization of cardiac pacemaker ...
... May be less likely to cause tachycardia and cardiac arrhythmias than atropine Can cause an initial paradoxical bradycardia and AV block when given IV. This effect is usually overcome as plasma levels become therapeutic Note: Hypothermia results in decreased depolarization of cardiac pacemaker ...
IJBCP International Journal of Basic & Clinical
... 2 weakness was the most common symptom, followed by abdominal pain and headache. These are typical symptoms of anemia. Low oxygen carrying capacity of blood causes these symptoms. In anemic patients, PIH and other diseases were common. Hence seven drugs were prescribed to 26.7% patients. A comorbid ...
... 2 weakness was the most common symptom, followed by abdominal pain and headache. These are typical symptoms of anemia. Low oxygen carrying capacity of blood causes these symptoms. In anemic patients, PIH and other diseases were common. Hence seven drugs were prescribed to 26.7% patients. A comorbid ...
Slide 1
... Preventable Adverse Drug Reactions: A Focus on Drug Interactions Protease Inhibitors Backgrounder -Protease inhibitors are members of a class of antiretrovirals that are generally considered to be the most potent therapeutic agents for HIV to date. In order for these drugs to be effective and to min ...
... Preventable Adverse Drug Reactions: A Focus on Drug Interactions Protease Inhibitors Backgrounder -Protease inhibitors are members of a class of antiretrovirals that are generally considered to be the most potent therapeutic agents for HIV to date. In order for these drugs to be effective and to min ...
The Effect Of Diabetes Mellitus On Exposure To Tuberculosis Drugs
... Pharmacokinetic parameters of tuberculosis drugs in Tanzanian diabetic and non-diabetic TB patients in northern Tanzania ...
... Pharmacokinetic parameters of tuberculosis drugs in Tanzanian diabetic and non-diabetic TB patients in northern Tanzania ...
nektar - Moodle Lille 2
... PEGylation interests Creat new drugs with optimized properties Reposition approves products for new indications Rescue non-viable drug candidates ...
... PEGylation interests Creat new drugs with optimized properties Reposition approves products for new indications Rescue non-viable drug candidates ...
Tranquilizer drug forensics - Neuroscience Consulting, Inc
... are formed either on the subunits, or where subunits meet or within the chloride pore itself. In this article, the chloride pore assembly responsive to GABA or drug stimulation is referred to as the “GABAA receptor complex.” In contrast to the barbiturates, benzodiazepines cannot directly open the ...
... are formed either on the subunits, or where subunits meet or within the chloride pore itself. In this article, the chloride pore assembly responsive to GABA or drug stimulation is referred to as the “GABAA receptor complex.” In contrast to the barbiturates, benzodiazepines cannot directly open the ...
anxiolytics2011-09
... peak plasma levels. Rifampin and liver microenzyme stimulators, decrease its plasma half-life. Clinical effects: It is associated with the decrease of sleep latency. It carries less risk of developing amnesia or withdrawal symptoms. ...
... peak plasma levels. Rifampin and liver microenzyme stimulators, decrease its plasma half-life. Clinical effects: It is associated with the decrease of sleep latency. It carries less risk of developing amnesia or withdrawal symptoms. ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.