TOPICALLY APPLIED NSAIDs IN THE TREATMENT OF PAIN
... major advantages: 1) higher concentrations of NSAIDs are delivered to the desired site (e.g. up to 100 times higher NSAID occurs in synovial fluid compared to that from NSAID blood levels; 2) only 1-3% of NSAID is systemically absorbed, reducing the possibility of gastrointestinal upset or ulcers; 3 ...
... major advantages: 1) higher concentrations of NSAIDs are delivered to the desired site (e.g. up to 100 times higher NSAID occurs in synovial fluid compared to that from NSAID blood levels; 2) only 1-3% of NSAID is systemically absorbed, reducing the possibility of gastrointestinal upset or ulcers; 3 ...
167-987-1-SP - Journal of Ayurveda and Holistic Medicine
... Upper respiratory infections are very common due their high incidence in paediatric age group and recurrence also is more because of low immunity. Currently available options of treatment for the management of Upper respiratory tract infections are Decongestants, analgesics and Anti-biotics. However ...
... Upper respiratory infections are very common due their high incidence in paediatric age group and recurrence also is more because of low immunity. Currently available options of treatment for the management of Upper respiratory tract infections are Decongestants, analgesics and Anti-biotics. However ...
alcohol, drugs and substance misuse policy
... been accepted or followed; disciplinary action will be taken, which could result in a formal warning up to and including dismissal. 8.4.3 Where misuse is not eliminated or controlled sufficiently to allow resumption of normal working arrangements within a reasonable period of time or, if appropriate ...
... been accepted or followed; disciplinary action will be taken, which could result in a formal warning up to and including dismissal. 8.4.3 Where misuse is not eliminated or controlled sufficiently to allow resumption of normal working arrangements within a reasonable period of time or, if appropriate ...
POLIGUGUL COMPLEX
... Cholesterol-lowering drugs; available by prescription , aren’t only expensive but are associated with some very serious adverse side effects. However, there are natural substances that can help lower cholesterol safely and even more effectively than these dangerous drugs. Some not all patients respo ...
... Cholesterol-lowering drugs; available by prescription , aren’t only expensive but are associated with some very serious adverse side effects. However, there are natural substances that can help lower cholesterol safely and even more effectively than these dangerous drugs. Some not all patients respo ...
Guidelines for Governments on Preventing the Illegal Sale
... become a significant problem in many countries because they have partly replaced traditional drugs of abuse. In several countries, the abuse of prescription drugs has become a major problem, second only to the abuse of cannabis. The illegal sale of pharmaceuticals is facilitated by websites that pre ...
... become a significant problem in many countries because they have partly replaced traditional drugs of abuse. In several countries, the abuse of prescription drugs has become a major problem, second only to the abuse of cannabis. The illegal sale of pharmaceuticals is facilitated by websites that pre ...
BASS & ULLMAN, E G.
... Both prescription and over-the-counter are bronchodilators short-acting (OTC) The OTC drugs generally contain available. lesser amounts of the active agent than prescription forms and are effective for a shorter period. They may be useful, however, asthma for mild treatment temporary as Ready availa ...
... Both prescription and over-the-counter are bronchodilators short-acting (OTC) The OTC drugs generally contain available. lesser amounts of the active agent than prescription forms and are effective for a shorter period. They may be useful, however, asthma for mild treatment temporary as Ready availa ...
MPA Spring Convention 2017 Edited
... i. a drug that is identical or nearly identical to an approved drug, or a marketed drug ii. a drug, a component of which is a bulk drug substance that is a component of an approved drug or a marketed drug, unless there is a change that produces for an individual patient a clinical difference, as det ...
... i. a drug that is identical or nearly identical to an approved drug, or a marketed drug ii. a drug, a component of which is a bulk drug substance that is a component of an approved drug or a marketed drug, unless there is a change that produces for an individual patient a clinical difference, as det ...
Role of US Military Research Programs in the Development of US
... problem in veterans returning from the Korean War. Compliance with chloroquine prophylaxis was good, so malaria symptoms developed only after troops departed from Korea. Dr. Alf Alving (University of Chicago) led a research team under contract to the US Army that evaluated the safety and efficacy of ...
... problem in veterans returning from the Korean War. Compliance with chloroquine prophylaxis was good, so malaria symptoms developed only after troops departed from Korea. Dr. Alf Alving (University of Chicago) led a research team under contract to the US Army that evaluated the safety and efficacy of ...
Structure-based drug design meets the ribosome
... set requiring a certain number of features to be satisfied for the pharmacophore to be robust. This requires an alignment of ligand molecules that best satisfies the model and therefore works best when there is a single, well-defined binding pocket where active ligands bind. Given that this is not t ...
... set requiring a certain number of features to be satisfied for the pharmacophore to be robust. This requires an alignment of ligand molecules that best satisfies the model and therefore works best when there is a single, well-defined binding pocket where active ligands bind. Given that this is not t ...
Drugs for Parkinson`s disease
... Pharmacologic effects: The effects on bradykinesia and rigidity are more rapid and complete than the effects on tremor. Other motor defects in PD improve. The psychological wellbeing of patient is also improved. ...
... Pharmacologic effects: The effects on bradykinesia and rigidity are more rapid and complete than the effects on tremor. Other motor defects in PD improve. The psychological wellbeing of patient is also improved. ...
PowerPoint Presentation - Lecture 13
... • Diagnostic Aids – Used to locate leisions or foreign objects & to provide anesthesia. Fluorescein sodium – a dye turns scratches green & circle foreign objects in green. • Topical Anesthetics - used for exams & removal foreign objects proparacaine HCL (Ophthaine, Ophthetic), tetracaine HCL (Pontoc ...
... • Diagnostic Aids – Used to locate leisions or foreign objects & to provide anesthesia. Fluorescein sodium – a dye turns scratches green & circle foreign objects in green. • Topical Anesthetics - used for exams & removal foreign objects proparacaine HCL (Ophthaine, Ophthetic), tetracaine HCL (Pontoc ...
Coated balloons
... approved to be dissolved into the blood and used in the body, degrades to citric acid and alcohol; disrupts the crystalline structure of paclitaxel and makes the compound absorbable to the tissue ...
... approved to be dissolved into the blood and used in the body, degrades to citric acid and alcohol; disrupts the crystalline structure of paclitaxel and makes the compound absorbable to the tissue ...
pain management guidelines - About PRC
... 3. In opioid naïve patients start with low dose, short acting opioids and titrate for effect. 4. Avoid meperidine (Demerol®) and the mixed agonist-antagonist opioids [e.g. butorphanol tartarate (Stadol®), nalbuphine hydrochloride (Nubain®), and pentazocine hydrochloride and naloxone hydrochloride (T ...
... 3. In opioid naïve patients start with low dose, short acting opioids and titrate for effect. 4. Avoid meperidine (Demerol®) and the mixed agonist-antagonist opioids [e.g. butorphanol tartarate (Stadol®), nalbuphine hydrochloride (Nubain®), and pentazocine hydrochloride and naloxone hydrochloride (T ...
Click here B. Pharmacy Syllabus
... Note: Examiner to set eight questions and the candidates are required to attempt any five. 1. Introduction: Definition, history, scope and development of Pharmacognosy. (2) 2. Sources of drugs: Biological, marine, geographical and plant tissue cultures. (4) 3. Classification of drugs: Alphabetical, ...
... Note: Examiner to set eight questions and the candidates are required to attempt any five. 1. Introduction: Definition, history, scope and development of Pharmacognosy. (2) 2. Sources of drugs: Biological, marine, geographical and plant tissue cultures. (4) 3. Classification of drugs: Alphabetical, ...
Simultaneous Spectrophotometric Determination of Drotaverine
... data processing and hence can be applied only on recording spectrophotometers with such facilities. This method was employed totally to eliminate the spectral interference from one of two drugs while eliminating the other drug. This was achieved by selecting the zero crossing point on the derivative ...
... data processing and hence can be applied only on recording spectrophotometers with such facilities. This method was employed totally to eliminate the spectral interference from one of two drugs while eliminating the other drug. This was achieved by selecting the zero crossing point on the derivative ...
Review Article TRANSDERMAL DRUG DELIVERY SYSTEM
... stratum corneum. In the last two decades, the transdermal drug delivery system has become a proven technology that offers significant clinical benefits over other dosage forms. Because transdermal drug delivery offers controlled as well as predetermined rate of release of the drug into the patient, ...
... stratum corneum. In the last two decades, the transdermal drug delivery system has become a proven technology that offers significant clinical benefits over other dosage forms. Because transdermal drug delivery offers controlled as well as predetermined rate of release of the drug into the patient, ...
Ketaset-Rompun Anesthesia Induces a Conditioned Taste Aversion
... agents, and the present study replicates and extends these findings to a different class of anesthetic (Ketaset-Rompun). BureSova and BureS (1977) have reported that Allobarbitol anesthesia produces a CTA, and Bermudez-Rattoni et al. (1988) have reported similar effects with Rompun alone. Although t ...
... agents, and the present study replicates and extends these findings to a different class of anesthetic (Ketaset-Rompun). BureSova and BureS (1977) have reported that Allobarbitol anesthesia produces a CTA, and Bermudez-Rattoni et al. (1988) have reported similar effects with Rompun alone. Although t ...
The Ethics of Regulatory Mandates for Pediatric Research
... Regulatory Mandates: Risk and Redundancy Defining the ethical problems that exist in pediatric medicine is crucial to judging the appropriateness of conducting research in children. First and foremost is the realization that children are exposed to therapeutic agents on a continual basis, regardless ...
... Regulatory Mandates: Risk and Redundancy Defining the ethical problems that exist in pediatric medicine is crucial to judging the appropriateness of conducting research in children. First and foremost is the realization that children are exposed to therapeutic agents on a continual basis, regardless ...
IFU - Beckman Coulter
... 1. The test is designed for use with human urine only. 2. Do not dilute the urine samples since this is a qualitative assay. Dilution of samples may produce erroneous results. 3. Interference has been demonstrated from mefenamic acid, a nonopioid analgesic. 9 4. Adulteration of the urine sample may ...
... 1. The test is designed for use with human urine only. 2. Do not dilute the urine samples since this is a qualitative assay. Dilution of samples may produce erroneous results. 3. Interference has been demonstrated from mefenamic acid, a nonopioid analgesic. 9 4. Adulteration of the urine sample may ...
Hydroxyurea - Thalassemia Dubai
... Zeng YT, Huang SZ, Ren ZR, et al. Hydroxyurea therapy in β-thalassaemia intermedia: improvement in haematological parameters due to enhanced ...
... Zeng YT, Huang SZ, Ren ZR, et al. Hydroxyurea therapy in β-thalassaemia intermedia: improvement in haematological parameters due to enhanced ...
Oral Drug Therapy Guidelines in Surgical Patients
... when they are likely to be restarted. If a patient requires emergency surgery then the surgical team should liaise with the anaesthetist to discuss which drugs should and should not be stopped prior to surgery and when to restart any discontinued drugs. A patient may be ‘Nil-by-mouth’ for several re ...
... when they are likely to be restarted. If a patient requires emergency surgery then the surgical team should liaise with the anaesthetist to discuss which drugs should and should not be stopped prior to surgery and when to restart any discontinued drugs. A patient may be ‘Nil-by-mouth’ for several re ...
Intravenous Agents - RAH
... the rapidly acting agents are relatively unionised at plasma pH and are absorbed according to their lipid solubility thiopentone, being highly lipid soluble, equilibrates with the brain rapidly phenobarbital, with relatively low lipid solubility, may take over 15 mins to achieve unconsciousness when ...
... the rapidly acting agents are relatively unionised at plasma pH and are absorbed according to their lipid solubility thiopentone, being highly lipid soluble, equilibrates with the brain rapidly phenobarbital, with relatively low lipid solubility, may take over 15 mins to achieve unconsciousness when ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.