![Dr.Chandrika Rao](http://s1.studyres.com/store/data/008605640_1-b69ebb2a9b78ad27afd2c20226231ab8-300x300.png)
Dr.Chandrika Rao
... In thyroid deficiency, increased D2 activity maintains normal T3 concentration despite reduced T4 concentrations in brain. Thyroid hormones are present in CSF at less than ten times the serum concentrations . The findings of this study point out that both T3 and T4 should be tested with TSH in adole ...
... In thyroid deficiency, increased D2 activity maintains normal T3 concentration despite reduced T4 concentrations in brain. Thyroid hormones are present in CSF at less than ten times the serum concentrations . The findings of this study point out that both T3 and T4 should be tested with TSH in adole ...
adrenal & thyroid
... - Graves’ ophthalmopathy: - edema and inflammation of the extraocular muscles - increase in orbital connective tissue and fat - may be persistent and lead to loss of vision ...
... - Graves’ ophthalmopathy: - edema and inflammation of the extraocular muscles - increase in orbital connective tissue and fat - may be persistent and lead to loss of vision ...
Kocher-Debre-Semelaigne Syndrome: Response to
... muscles. Investigations revealed delayed osseous maturation, elevated total cholesterol with low T3 and T4 with grossly elevated TSH. He was diagnosed as a case of congenital hypothyroidism with muscular pseudohypertrophy and thyroxine replacement therapy was initiated. A rare presentation of congen ...
... muscles. Investigations revealed delayed osseous maturation, elevated total cholesterol with low T3 and T4 with grossly elevated TSH. He was diagnosed as a case of congenital hypothyroidism with muscular pseudohypertrophy and thyroxine replacement therapy was initiated. A rare presentation of congen ...
Short-Term Hyperthyroidism Followed by Transient
... euthyroid (Fig 1). However, basal TSH remained extremely low and a TRH test did not show TSH response by 2 months old (postmenstrual age: 37 weeks). TSH was 0.17 U/mL before testing and 0.54 U/mL at 30 minutes after the TRH test. At 4 months old, for the first time, TSH increased significantly fro ...
... euthyroid (Fig 1). However, basal TSH remained extremely low and a TRH test did not show TSH response by 2 months old (postmenstrual age: 37 weeks). TSH was 0.17 U/mL before testing and 0.54 U/mL at 30 minutes after the TRH test. At 4 months old, for the first time, TSH increased significantly fro ...
Thyroid Hormones in Serum and Plasma Using SPE Extraction and
... Thyroid hormones are endogenous hormones that play an important role in many biological processes, including growth, development and metabolism. Most of the thyroid hormones circulating in the blood are bound to proteins and only a small fraction of circulating hormones are in their biologically act ...
... Thyroid hormones are endogenous hormones that play an important role in many biological processes, including growth, development and metabolism. Most of the thyroid hormones circulating in the blood are bound to proteins and only a small fraction of circulating hormones are in their biologically act ...
Severe cholestatic jaundice secondary to hyperthyroidism
... rifampicin can also be implicated as well [1–5]. Thyrotoxicosis is known to cause a variety of nonspecific abnormalities in liver biochemistries, but there has been no evidence to suggest that thyroid hormones have a direct toxic effect on the liver. The liver is the primary organ of thyroid hormone ...
... rifampicin can also be implicated as well [1–5]. Thyrotoxicosis is known to cause a variety of nonspecific abnormalities in liver biochemistries, but there has been no evidence to suggest that thyroid hormones have a direct toxic effect on the liver. The liver is the primary organ of thyroid hormone ...
A How to manage hypothyroid disease in pregnancy
... during pregnancy.9 Maternal and congenital hypothyroidism resulting from severe iodine deficiency are associated with profound neurologic impairment and mental retardation.1,3,10 If the condition is left untreated, cretinism can occur. Congenital cretinism is associated with growth failure, mental r ...
... during pregnancy.9 Maternal and congenital hypothyroidism resulting from severe iodine deficiency are associated with profound neurologic impairment and mental retardation.1,3,10 If the condition is left untreated, cretinism can occur. Congenital cretinism is associated with growth failure, mental r ...
Central hypothyroidism - Canadian Family Physician
... (Figure 1). Increased TSH levels are therefore indicative of the diagnosis, and normalization is seen during adequate treatment. In contrast, owing to hypothalamic or pituitary failure, TSH levels might not increase in response to low T3 and T4 levels. 6 Thyroid-stimulating hormone levels can, in fa ...
... (Figure 1). Increased TSH levels are therefore indicative of the diagnosis, and normalization is seen during adequate treatment. In contrast, owing to hypothalamic or pituitary failure, TSH levels might not increase in response to low T3 and T4 levels. 6 Thyroid-stimulating hormone levels can, in fa ...
grave problem
... At their nods, she continued. “The regulation of the system starts when the hypothalamus in the brain releases TRH, or thyrotropin-releasing hormone. This TRH acts on the pituitary, causing that gland in turn to release thyroidstimulating hormone. With me so far?” “You mean this all starts in the br ...
... At their nods, she continued. “The regulation of the system starts when the hypothalamus in the brain releases TRH, or thyrotropin-releasing hormone. This TRH acts on the pituitary, causing that gland in turn to release thyroidstimulating hormone. With me so far?” “You mean this all starts in the br ...
Path 24- Endocrine System [3-20
... What is thyroid storm? What is apathetic hyperthyroidism? How is hyperthyroidism diagnosed? Treatment? a. sudden onset of severe hyperthyroidism (Graves most common form); fever, tachycardia, possible death b. apathetic is thyrotoxicosis in elderly that doesn't have normal features due to their age ...
... What is thyroid storm? What is apathetic hyperthyroidism? How is hyperthyroidism diagnosed? Treatment? a. sudden onset of severe hyperthyroidism (Graves most common form); fever, tachycardia, possible death b. apathetic is thyrotoxicosis in elderly that doesn't have normal features due to their age ...
Carbamazepine, serum thyroid hormones and
... phenytoin, the changes in serum thyroid hormone levels during the use of antiepileptic drugs have been widely investigated. Carbamazepine and phenytoin seem to have a similar effect on thyroid function: serum thyroxine (T4) and free thyroxine concentrations decrease, but serum thyrotropin (TSH) leve ...
... phenytoin, the changes in serum thyroid hormone levels during the use of antiepileptic drugs have been widely investigated. Carbamazepine and phenytoin seem to have a similar effect on thyroid function: serum thyroxine (T4) and free thyroxine concentrations decrease, but serum thyrotropin (TSH) leve ...
InterBioTech TSH Human
... General information Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine ...
... General information Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine ...
Rabbit`s triiodothyronine (T3), thyroxin (T4) and the thyroid
... is controlled by TSH, the thyroid stimulating hormone. The increased production of Tyrosine is very important since it establishes the body to produce levodopa and dopamine, the lack of them causes muscle stiffness, tetany, spastic movements which one better known by the name of (Parkinson’s Disease ...
... is controlled by TSH, the thyroid stimulating hormone. The increased production of Tyrosine is very important since it establishes the body to produce levodopa and dopamine, the lack of them causes muscle stiffness, tetany, spastic movements which one better known by the name of (Parkinson’s Disease ...
phys chapter 76 [10-24
... o Free thyroid hormones diffuse through base of thyroid cells into surrounding capillaries o About ¾ of iodinated tyrosine in thyroglobulin never become thyroid hormones but remain MIT and DIT During digestion of thyroglobulin molecule to cause release of T4 and T3, these iodinated tyrosines also ...
... o Free thyroid hormones diffuse through base of thyroid cells into surrounding capillaries o About ¾ of iodinated tyrosine in thyroglobulin never become thyroid hormones but remain MIT and DIT During digestion of thyroglobulin molecule to cause release of T4 and T3, these iodinated tyrosines also ...
Chapter 30 Nuclear Physics and Radioactivity
... has a halflife of about 5730 years; it gradually decays away and becomes a smaller and smaller fraction of the total carbon in the plant tissue. This fraction can be measured, and tissue age deduced. Objects older than about 60,000 years cannot be dated this way – there is too little carbon1 ...
... has a halflife of about 5730 years; it gradually decays away and becomes a smaller and smaller fraction of the total carbon in the plant tissue. This fraction can be measured, and tissue age deduced. Objects older than about 60,000 years cannot be dated this way – there is too little carbon1 ...
Multiple Endocrine Neoplasia TYPE 2 Background
... administration of a beta-blocker can be considered. Reports of successful management using a calcium channel blocker rather than an alpha blocker have been noted. Many practitioners routinely treat patients with a beta-blocker, while others selectively treat patients based on blood pressure control ...
... administration of a beta-blocker can be considered. Reports of successful management using a calcium channel blocker rather than an alpha blocker have been noted. Many practitioners routinely treat patients with a beta-blocker, while others selectively treat patients based on blood pressure control ...
Chapter 18 - An Introduction to Chemistry: Nuclear
... The presentation of information in this chapter assumes that you can already perform the tasks listed below. You can test your readiness to proceed by answering the Review Questions at the end of the chapter. This might also be a good time to read the Chapter Objectives, which precede the Review Que ...
... The presentation of information in this chapter assumes that you can already perform the tasks listed below. You can test your readiness to proceed by answering the Review Questions at the end of the chapter. This might also be a good time to read the Chapter Objectives, which precede the Review Que ...
PowerPoint - Way of Life
... Primary relationships shift as women often feel like this is the time to take care of themselves and use their voice more than in the past Though these shifts can be stressful, they often lead to a new sense of freedom and self-empowerment Creating space to “fill up the cup” is critical in easing th ...
... Primary relationships shift as women often feel like this is the time to take care of themselves and use their voice more than in the past Though these shifts can be stressful, they often lead to a new sense of freedom and self-empowerment Creating space to “fill up the cup” is critical in easing th ...
Clinical Utility of Thyroperoxidase Antibody Testing
... arterial hypertension (PAH) has been well-recognized, yet the best method to screen for thyroid disease is unclear. Since there may be an underlying common immunopathologic link, we sought to determine whether testing for thyroperoxidase antibody (TPOAb) would be a useful screening tool for AITD in ...
... arterial hypertension (PAH) has been well-recognized, yet the best method to screen for thyroid disease is unclear. Since there may be an underlying common immunopathologic link, we sought to determine whether testing for thyroperoxidase antibody (TPOAb) would be a useful screening tool for AITD in ...
Hyperthyroidism and the Heart - Hellenic Journal of Cardiology
... heavy chain fusion (MHC-‚), adenylic cyclase (IV and V), and the Na-Ca antiporter, is suppressed.9 In addition, T3 has direct extragenic actions on the function of the Na, K, and Ca channels of the cellular membrane, thus affecting myocardial and vascular function. Three MHC isoforms have been found ...
... heavy chain fusion (MHC-‚), adenylic cyclase (IV and V), and the Na-Ca antiporter, is suppressed.9 In addition, T3 has direct extragenic actions on the function of the Na, K, and Ca channels of the cellular membrane, thus affecting myocardial and vascular function. Three MHC isoforms have been found ...
Thyroid Cancer - Stanford Nuclear Medicine
... Ø Papillary thyroid cancer (PTC) is the most common of all thyroid cancers, comprising approximately 70-75% of follicular cell derived cancers Ø Papillary cancer can occur in any age group, although its peak incidence in the fourth and fifth decades of life Ø It is more common in women than i ...
... Ø Papillary thyroid cancer (PTC) is the most common of all thyroid cancers, comprising approximately 70-75% of follicular cell derived cancers Ø Papillary cancer can occur in any age group, although its peak incidence in the fourth and fifth decades of life Ø It is more common in women than i ...
Jai guruji
... Kaan Bilgic, Kadriye KOC, et al showed that serum total thyroxine (TT4) and free triiodothyronine (FT3) were significantly higher in patients with psoriasis than in the control group. The average Psoriasis Area and Severity Index (PASI) score were significantly higher in this patients and this may b ...
... Kaan Bilgic, Kadriye KOC, et al showed that serum total thyroxine (TT4) and free triiodothyronine (FT3) were significantly higher in patients with psoriasis than in the control group. The average Psoriasis Area and Severity Index (PASI) score were significantly higher in this patients and this may b ...
OSTEOPOROSIS IN PATIENTS WITH HYPERTHYROIDISM
... Thyrotoxicosis is associated with elevated serum concentrations of osteocalcin and alkaline phosphatase and increased excretion of Ca and P in urine and stool. Enhanced bone resorption is accompanied by elevated urine concentrations of hydroxyproline and type I collagen cross linkages (2). Elevated ...
... Thyrotoxicosis is associated with elevated serum concentrations of osteocalcin and alkaline phosphatase and increased excretion of Ca and P in urine and stool. Enhanced bone resorption is accompanied by elevated urine concentrations of hydroxyproline and type I collagen cross linkages (2). Elevated ...
Twenty-four Hour Hormone Profiles of TSH, Free T3 and Free T4 in
... short-term benefit (Saravanan et al., 2005). However, combined T3/T4 therapy is still widely used (Blanchard, 2004; Woliner, 2003). Careful pharmacokinetic studies performed nearly 30 years ago showed that T3 if used as monotherapy for hypothyroidism, should be given at least three times a day to hav ...
... short-term benefit (Saravanan et al., 2005). However, combined T3/T4 therapy is still widely used (Blanchard, 2004; Woliner, 2003). Careful pharmacokinetic studies performed nearly 30 years ago showed that T3 if used as monotherapy for hypothyroidism, should be given at least three times a day to hav ...
Iodine-131
Iodine-131 (131I), also loosely and nonspecifically called radioiodine, is an important radioisotope of iodine discovered by Glenn Seaborg and John Livingood in 1938 at the University of California, Berkeley. It has a radioactive decay half-life of about eight days. It is associated with nuclear energy, medical diagnostic and treatment procedures, and natural gas production. It also plays a major role as a radioactive isotope present in nuclear fission products, and was a significant contributor to the health hazards from open-air atomic bomb testing in the 1950s, and from the Chernobyl disaster, as well as being a large fraction of the contamination hazard in the first weeks in the Fukushima nuclear crisis. This is because I-131 is a major uranium, plutonium fission product, comprising nearly 3% of the total products of fission (by weight). See fission product yield for a comparison with other radioactive fission products. I-131 is also a major fission product of uranium-233, produced from thorium.Due to its mode of beta decay, iodine-131 is notable for causing mutation and death in cells that it penetrates, and other cells up to several millimeters away. For this reason, high doses of the isotope are sometimes less dangerous than low doses, since they tend to kill thyroid tissues that would otherwise become cancerous as a result of the radiation. For example, children treated with moderate dose of I-131 for thyroid adenomas had a detectable increase in thyroid cancer, but children treated with a much higher dose did not. Likewise, most studies of very-high-dose I-131 for treatment of Graves disease have failed to find any increase in thyroid cancer, even though there is linear increase in thyroid cancer risk with I-131 absorption at moderate doses. Thus, iodine-131 is increasingly less employed in small doses in medical use (especially in children), but increasingly is used only in large and maximal treatment doses, as a way of killing targeted tissues. This is known as ""therapeutic use.""Iodine-131 can be ""seen"" by nuclear medicine imaging techniques (i.e., gamma cameras) whenever it is given for therapeutic use, since about 10% of its energy and radiation dose is via gamma radiation. However, since the other 90% of radiation (beta radiation) causes tissue damage without contributing to any ability to see or ""image"" the isotope, other less-damaging radioisotopes of iodine such as iodine-123 (see isotopes of iodine) are preferred in situations when only nuclear imaging is required. The isotope I-131 is still occasionally used for purely diagnostic (i.e., imaging) work, due to its low expense compared to other iodine radioisotopes. Very small medical imaging doses of I-131 have not shown any increase in thyroid cancer. The low-cost availability of I-131, in turn, is due to the relative ease of creating I-131 by neutron bombardment of natural tellurium in a nuclear reactor, then separating I-131 out by various simple methods (i.e., heating to drive off the volatile iodine). By contrast, other iodine radioisotopes are usually created by far more expensive techniques, starting with reactor radiation of expensive capsules of pressurized xenon gas.Iodine-131 is also one of the most commonly used gamma-emitting radioactive industrial tracer. Radioactive tracer isotopes are injected with hydraulic fracturing fluid to determine the injection profile and location of fractures created by hydraulic fracturing.Much smaller incidental doses of iodine-131 than those used in medical therapeutic procedures, are thought to be the major cause of increased thyroid cancers after accidental nuclear contamination. These cancers happen from residual tissue radiation damage caused by the I-131, and usually appear years after exposure, long after the I-131 has decayed.