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Section 2 - Introduction to Molecular Biology
Section 2 - Introduction to Molecular Biology

... • The DNA molecule is directional, because the sugars are asymmetrical – each sugar is connected to the strand “upstream” at its 5th carbon and “downstream” at its 3rd carbon. So you read the DNA sequence from the “5 prime” end to the “3’ ” end. • In replication, the double helix becomes unzipped an ...
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... stages of life may have a long-lasting influence on the expression of various genes, including some of those thought to be influencing the Western obesity epidemic. This forms part of a branch of science called epigenetics which is concerned with how our environment can change the way our genes are ...
THE DISCOVERY OF REVERSE TRANSCRIPTASE
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... proposed. Both scientists, however, had to have the conviction to believe and report what they were seeing, despite its being contrary to a seemingly unshakable paradigm. The discovery of reverse transcriptase has impacted life in and out of science in a myriad of ways. The ability to convert mRNA t ...
nutrigenomica
nutrigenomica

... stages of life may have a long-lasting influence on the expression of various genes, including some of those thought to be influencing the Western obesity epidemic. This forms part of a branch of science called epigenetics which is concerned with how our environment can change the way our genes are ...
Part 5 Intro to Genetics:
Part 5 Intro to Genetics:

... Genetic Engineering allows scientists to transfer DNA from one organisms to another. When an organism contains genes (foreign DNA) other than their own, they are called transgenic. Transgenic plants: one of the 1st transgenic organisms was a tobacco plant that had the gene of a firefly inside. The p ...
Chapter 8 Lecture Notes
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Gene Mutation, DNA Repair, and Transposition

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DNA and Gene Expression - Zanichelli online per la scuola

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Chapter 6 Genes and Gene Technology Section 1 We now know

... the cell and serve as chemical messengers. They also help determine how tall you will grow, what color your eyes are, if you are colored-blind or not, if your hair is curly or straight. These are a few examples of the importance of proteins. The three bases that code for a particular protein is call ...
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Manipulating DNA - Emerald Meadow Stables

... produce large quantities of a desired protein • To work with genes in the laboratory, biologists often use bacterial plasmids, small, circular DNA molecules – Plasmids can: • can carry virtually any gene, • can act as vectors, DNA carriers that move genes from one cell to another, and • are ideal fo ...
Endosymbiotic Hypothesis (Endosymbiosis)
Endosymbiotic Hypothesis (Endosymbiosis)

... chloroplasts resemble cyanobacteria in that they divide similarly (binary fission) • 1920: Ivan Wallin notices same thing for mitochondrion. • (nobody notices) • In 1967, Margulis offers evidence that these organelles have separate DNA from the rest of the cell (their own separate genome), and….. ...
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Molecular cloning



Molecular cloning is a set of experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms. The use of the word cloning refers to the fact that the method involves the replication of one molecule to produce a population of cells with identical DNA molecules. Molecular cloning generally uses DNA sequences from two different organisms: the species that is the source of the DNA to be cloned, and the species that will serve as the living host for replication of the recombinant DNA. Molecular cloning methods are central to many contemporary areas of modern biology and medicine.In a conventional molecular cloning experiment, the DNA to be cloned is obtained from an organism of interest, then treated with enzymes in the test tube to generate smaller DNA fragments. Subsequently, these fragments are then combined with vector DNA to generate recombinant DNA molecules. The recombinant DNA is then introduced into a host organism (typically an easy-to-grow, benign, laboratory strain of E. coli bacteria). This will generate a population of organisms in which recombinant DNA molecules are replicated along with the host DNA. Because they contain foreign DNA fragments, these are transgenic or genetically modified microorganisms (GMO). This process takes advantage of the fact that a single bacterial cell can be induced to take up and replicate a single recombinant DNA molecule. This single cell can then be expanded exponentially to generate a large amount of bacteria, each of which contain copies of the original recombinant molecule. Thus, both the resulting bacterial population, and the recombinant DNA molecule, are commonly referred to as ""clones"". Strictly speaking, recombinant DNA refers to DNA molecules, while molecular cloning refers to the experimental methods used to assemble them.
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