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... The precise timing of events in the brain has consequences for intracellular processes, synaptic plasticity, integration and network behaviour. Pyramidal neurons, the most widespread excitatory neuron of the neocortex have multiple spike initiation zones, which interact via dendritic and somatic spi ...
Retrograde Signaling in the Development and Modification of
Retrograde Signaling in the Development and Modification of

... receive both positive and negative retrograde signals before the decision on synapse formation is made. The presynaptic receptors for these muscle surface proteins and the downstream transduction mechanism involved in growth cone responses are unknown. Because elevation of Ca2/ usually results in an ...
Chapter 2: The Biological Basis of Behavior
Chapter 2: The Biological Basis of Behavior

... him to turn it off, he asks why she is just noticing it now when he's had it on for over 20 minutes. Which of the following psychological explanations is the LEAST plausible explanation of what occurred after she opened the door? a. The volume of the music reached the threshold needed to fire her ne ...
Do neurons generate monopolar current sources?
Do neurons generate monopolar current sources?

... postsynaptic currents indicated in Fig. 1), the setting of extracellular current and return current will not be instantaneous, and there will be a transient time during which charges will accumulate in the postsynaptic region. During this transient time, Kirchhoff’s current rule does not apply (the ...
By Majid Fotuhi, MD, PhD
By Majid Fotuhi, MD, PhD

... remained significant but plateaued three months after students had completed their exams, when they were no longer working hard in memorizing long lists of medical terms. In contrast, hippocampal expansion continued during these three resting months. The surprising growth in hippocampus may be in pa ...
another study guide
another study guide

... 6. Identify and explain how drugs and other chemicals alter neurotransmissions. 7. Identify the major divisions of the nervous system and describe their functions, noting the three types of neurons that transmit information through the system. 8. Describe the nature and functions of the endocrine sy ...
Chapter 11 Efferent Division: Autonomic and Somatic Motor Control
Chapter 11 Efferent Division: Autonomic and Somatic Motor Control

... They differ in their affinity for catecholamines: – Beta-1 receptors respond equally strongly to both epinephrine and norepinephrine – Beta-2 receptors are more sensitive to epinephrine than to norepinephrine • Beta-2 receptors are not innervated • This limits their exposure to norepinephrine becau ...
Chapter 28 - Montville.net
Chapter 28 - Montville.net

... 28.18 CONNECTION: fMRI scans can provide insight into brain structure and function  fMRI – A scanning and imaging technology used to study brain functions – Used on conscious patients – Monitors changes in blood oxygen usage in the brain – Correlates to regions of intense brain function ...
Frankland lecture FINAL
Frankland lecture FINAL

... connections between populations of neurons (or ensembles) that are active during encoding increased synaptic strength between these neurons increases likelihood that same spatiotemporal pattern of activity that occurred at encoding is recreated at later times (i.e., retrieval) ...
Dendrites as separate compartment – local protein synthesis
Dendrites as separate compartment – local protein synthesis

... assume that local protein synthesis in subsynaptic region of dendrites is possible. A discovery that high frequency, tetanic stimulation causes a long-term change in the efficacy of stimulated synapses led to an extensive research on the molecular basis of that phenomenon. Long term potentiation (LT ...
uncorrected page proofs
uncorrected page proofs

... invisible to the naked eye. You cannot see that it is densely packed with structures, systems, functions, connections and interconnections, many of which are still not fully understood. Within the brain’s tissue are roughly 86 billion individual nerve cells called neurons. Each neuron is connected t ...
Honors Thesis
Honors Thesis

... describes a neuron firing after being released from inhibiting inputs. ...
doc Lecuter and chapter notes
doc Lecuter and chapter notes

... ionotropic receptor: a kind of neurotransmitter receptor that opens in direct response to a neurotransmitter binding to it, produces faster potentials metabotropic receptor: a kind of neurotransmitter receptor that opens in response to the neurotransmitter binding to a G protein, activating an enzym ...
Chapter 2: Psychology As a Science
Chapter 2: Psychology As a Science

...  Both sides of the brain are involved in everything we do due to ...
Psychobiology—Behavioral Problems Seeking Biological Solutions
Psychobiology—Behavioral Problems Seeking Biological Solutions

... interesting species to be sure, but nevertheless not the pinnacle of evolution much as we may wish it were so. Hirsch and Jacobsen, writing on neuronal development, hypothesize that neuronal invariance and variance are the properties of two types of neurons, "macro" and "micro" neurons, respectively ...
Dear Notetaker:
Dear Notetaker:

... Characteristics of Dorsal Pathway Neurons o Receives visual information and transform it into the control of action o The dorsal pathway needs input about object’s location size and shape  Input sent to dorsal pathway is from ventral pathway, but not in the same amount of detail that ventral proces ...
The CEMI Field Theory
The CEMI Field Theory

... 1986) proposed that the neurons representing features of an object are transiently coupled through synchronous firing. More recently, Pascal Fries formulated the ‘communication through coherence’ (CTC) hypothesis whereby neural communication between neurons was proposed to depend on their degree of ...
The Autonomic Nervous System
The Autonomic Nervous System

... --these neurons release nor-epinephrine (NE). --They are mostly sympathetic postganglionic neuron. --There are two main types of receptors: alpha( ) & Beta( ) receptors. --Action of Norepinephrine is at synapse is longer than Ach. ...
Materials - Web Adventures
Materials - Web Adventures

... the cell body are projections called dendrites that pick up messages or signals from other neurons. Each neuron also has a long extension called an axon that carries signals away from the cell. The end of the axon divides into many branches with swollen tips known as synaptic terminals. The process ...
Neurobiology of Behaviour
Neurobiology of Behaviour

... An accessible nervous system A repetitive behaviour, the CPG can be initiated in isolated ganglia An easily elicited behaviour Understanding of CPGs important comparatively across species ...
Learning-related changes in coordinated fast oscillations
Learning-related changes in coordinated fast oscillations

... CMBN, Rutgers University, Newark, NJ. The BLA is thought to facilitate memory formation by the medial temporal lobe in emotionally-arousing conditions. To study how the BLA mediates this effect, we simultaneously recorded neuronal activity in the BLA, perirhinal and entorhinal cortices. Given earlie ...
Evolution of the Nervous System
Evolution of the Nervous System

... Transmission across a synapse is carried out by neurotransmitters Sudden rise in calcium at end of one neuron Stimulates synaptic vesicles to merge with the presynaptic membrane Neurotransmitter molecules are released into the synaptic cleft ...
Evolution of the Nervous System
Evolution of the Nervous System

... Transmission across a synapse is carried out by neurotransmitters Sudden rise in calcium at end of one neuron Stimulates synaptic vesicles to merge with the presynaptic membrane Neurotransmitter molecules are released into the synaptic cleft ...
Document
Document

... • Synaptic transmission and neural coding – All-or-none law – a neuron is either firing action potential, or not, so how can the nervous system code for/represent complexity of experience? – Power of nervous system lies in the complexity of the connections between neurons – Lock-and-key action – the ...
The Maternal Brain
The Maternal Brain

... and learning as well as emotions, appear to play a major role in causing these behavioral changes. Some fascinating work by Catherine Woolley and Bruce McEwen of the Rockefeller University showed ebb-and-flow variations in the CA1 region of the hippocampus during a female rat’s estrous cycle (the equ ...
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Activity-dependent plasticity

A defining feature of the brain is its capacity to undergo changes based on activity-dependent functions, also called activity-dependent plasticity. Its ability to remodel itself forms the basis of the brain’s capacity to retain memories, improve motor function, and enhance comprehension and speech amongst other things. It is this trait to retain and form memories that is functionally linked to plasticity and therefore many of the functions individuals perform on a daily basis. This plasticity is the result of changed gene expression that occurs because of organized cellular mechanisms.The brain’s ability to adapt toward active functions has allowed humans to specialize in specific processes based on relative use and activity. For example, a right-handed person may perform any movement poorly with his/her left hand but continuous practice with the less dominant hand can make both hands just as able. Another example is if someone was born with a neurological disorder such as autism or had a stroke that resulted in a disorder, then they are capable of retrieving much of their lost function by practicing and “rewiring” the brain in order to incorporate these lost manners. Thanks to the pioneers within this field, many of these advances have become available to most people and many more will continue to arrive as new features of plasticity are discovered.
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