• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
DEVELOPMENT OF SUSTAINED RELEASE MATRIX TABLET OF TRAMADOL HYDROCHLORIDE  Research Article
DEVELOPMENT OF SUSTAINED RELEASE MATRIX TABLET OF TRAMADOL HYDROCHLORIDE Research Article

... drug and other auxiliary excipients to make a wet mass using a glass mortar and pestle; then passed through sieve to prepare granules; dried in hot air oven at 60oC for 30 min; then magnesium stearate and talc were added as the lubricant/ glidant and thoroughly blended for 5min and were sieved throu ...
Pirlimycin - American Academy of Veterinary Pharmacology and
Pirlimycin - American Academy of Veterinary Pharmacology and

... Mastitis (treatment)—Cows, lactating: Pirlimycin is indicated in the treatment of clinical and subclinical mastitis caused by Staphylococcus aureus, Streptococcus agalactiae, Streptococcus dysgalactiae, and Streptococcus uberis. {R-1} In refractory cases of chronic Staphylococcus aureus mastitis, ad ...
Synthesis and Characterizat /Cloisite30B (MMT) Nanoco
Synthesis and Characterizat /Cloisite30B (MMT) Nanoco

Inhalation  rate  of  sodium  cromoglycate ... plasma  pharmacokinetics  and  protection  against
Inhalation rate of sodium cromoglycate ... plasma pharmacokinetics and protection against

... C-fibre activation [6] may also be a factor. Secondly, SCG is highly effective at blocking adenosine- and AMPinduced bronchoconstriction consistent with its action on bronchial mast cells, [20). Thirdly, AMP may be used to provoke reproducible bronchoconstriction and therefore provide dose-response ...
Quantitative Estimation of Barbiturates in Blood by Ultra
Quantitative Estimation of Barbiturates in Blood by Ultra

File
File

... • Clearance is the rate at which a drug is eliminated from a specific volume of blood per unit of time ...
Correlating In Vitro Data to In Vivo Findings for Risk
Correlating In Vitro Data to In Vivo Findings for Risk

rotational motion
rotational motion

... CENTER OF GRAVITY • A uniform carpenter's square has the shape of an L, as shown in the figure. Locate the center of mass relative to the origin of the coordinate system. ...
Document
Document

Thyroid
Thyroid

Guideline on the Clinical Investigation of the Pharmacokinetics of
Guideline on the Clinical Investigation of the Pharmacokinetics of

... Mass-balance studies are not useful for determining the excretion pattern of the drug and drug-related material. Excreted proteins are not necessarily recovered in urine or faeces as intact substance, but are instead metabolised and reabsorbed as amino acids and incorporated in the general protein ...
Management of New Onset Atrial Fibrillation
Management of New Onset Atrial Fibrillation

... Hence, the best answer is #4. #3 would be acceptable if there is some reason not to do electrical cardioversion, or if there is any expectation that he may have recurrent episodes of AF and might be suitable for a pill in the pocket regimen, but this does not appear indicted in this first presentati ...
RP-HPLC METHOD FOR THE ESTIMATION OF VALACYCLOVIR IN BULK AND
RP-HPLC METHOD FOR THE ESTIMATION OF VALACYCLOVIR IN BULK AND

... Virus (VZV). Acyclovir oral bioavailability was increased when administered in the form of VAL2 and VAL rapidly converted to Acyclovir in vivo which inhibits DNA synthesis. VAL is available as tablet dosage form in market and few HPLC3-5 methods were reported for the estimation of VAL in pharmaceuti ...
Misoprostol
Misoprostol

... • concomitant antacid use reduces total availability ...
PowerPoint Presentation - Lecture 13
PowerPoint Presentation - Lecture 13

... • Body needs only a small amt. of vitamins daily easily obtained through a well-balanced diet • Vitamin supplements not necessary if a well-balanced diet consumed • Vitamin deficiencies can cause cellular and organ dysfunction - may result in slow recovery from illness • Most people use vitamins for ...
General Anesthetics
General Anesthetics

... INHALED ANESTHETICS: MECHANISM OF ACTION At the neurophysiological level - Early depressive effect on substantia gelatinosa - Blockade of small inhibitory neurons (e.g Golgi type II cells) in several brain areas. - Progressive depression of the ascending pathways in the reticular activating system. ...
PancreaticHormone&AntidiabeticDrugs
PancreaticHormone&AntidiabeticDrugs

... defects of insulin secretion and action, insulin resistance. ...
DEVELOPMENT AND VALIDATION OF UV SPECTROSCOPIC METHOD FOR DETERMINATION  OF METOCLOPRAMIDE HYDROCHLORIDE IN BULK AND TABLET FORMULATION 
DEVELOPMENT AND VALIDATION OF UV SPECTROSCOPIC METHOD FOR DETERMINATION  OF METOCLOPRAMIDE HYDROCHLORIDE IN BULK AND TABLET FORMULATION 

... successfully  employed  for  their  quantitative  determinations  using  the UV spectrophotometric method. The λmax of the drug for analysis  was determined by taking scans of the drug sample solutions in the  entire UV region. It was found to be that only one peak was observed  in this method at th ...
Liquid Equipoise Anabolic Androgenic Steroids CAS 13103-34
Liquid Equipoise Anabolic Androgenic Steroids CAS 13103-34

... Water retention with this drug would therefore be slightly higher than that with Deca-Durabolin (with an estimated 20% conversion), but much less than we would find with a stronger compound. While there is still a chance of encountering an estrogen related side effect as such when using Equipoise, ...
Determination of Ramelteon in Tablet Dosage Form by Novel
Determination of Ramelteon in Tablet Dosage Form by Novel

... reproducibility of the methods. The linearity for all three methods (LRE, SA and 1D) over the concentration 10-50 µg/mL was assured as 100.03%, 99.89% and 99.85% respectively with acceptable standard deviation (Table 4). The recovery method was adopted to assure accuracy of the methods which were fo ...
2.6 Exact Equations and Integrating Factors
2.6 Exact Equations and Integrating Factors

... solution of Eq. (24) can then be obtained by the method described in the first part of this section. The solution found in this way also satisfies Eq. (23), since the integrating factor µ can be canceled out of Eq. (24). A partial differential equation of the form (26) may have more than one solutio ...
Comparison of Tibial Intraosseous, Sternal Intraosseous
Comparison of Tibial Intraosseous, Sternal Intraosseous

... The Advanced Cardiac Life Support (ACLS) recommendation for the endotracheal administration of epinephrine is 2 to 2.5 times the IV dose. The Pediatric Advanced Life Support (PALS) recommendation for endotracheal epinephrine is 10 times the IV dose. Whereas no studies were used to establish these do ...
Il corretto uso dei diuretici nello scompenso cardiaco
Il corretto uso dei diuretici nello scompenso cardiaco

... infusion arm received daily doses of loop diuretic likely insufficient to reach the pharmacokinetic threshold ...
IMPAACT P1093: Phase I/II, Multi-Center, Open
IMPAACT P1093: Phase I/II, Multi-Center, Open

... • To evaluate the antiviral activity of dolutegravir in combination with an OBT by measuring virologic response in infants, children and adolescents at weeks 24 and 48 • To evaluate the effect on immunologic response from baseline to weeks 24 and 48 • To assess changes in HIV-1 genotype and phenotyp ...
LAPLACE SUBSTITUTION METHOD FOR SOLVING
LAPLACE SUBSTITUTION METHOD FOR SOLVING

... PDEs are used to formulate problems involving functions of several variables, and are either solved by hand, or used to create a relevant computer model. The separation of variables is any of several methods for solving ordinary and partial differential equations, in which algebra allows one to rewr ...
< 1 ... 66 67 68 69 70 71 72 73 74 ... 157 >

Plateau principle

The plateau principle is a mathematical model or scientific law originally developed to explain the time course of drug action The principle has wide applicability in pharmacology, physiology, nutrition, biochemistry and system dynamics. It applies whenever a drug or nutrient is infused or ingested at a relatively constant rate and when a constant fraction is eliminated during each time interval. Under these conditions, any change in the rate of infusion leads to an exponential increase or decrease until a new level is achieved. This behavior is also called an approach to steady state because rather than causing an indefinite increase or decrease, a natural balance is achieved when the rate of infusion or production is balanced by the rate of loss.An especially important use of the plateau principle is to study the renewal of tissue constituents in the human and animal body. In adults, daily synthesis of tissue constituents is nearly constant, and most constituents are removed with a first order reaction rate. Applicability of the plateau principle was recognized during radiotracer studies of protein turnover in the 1940s by Rudolph Schoenheimer and David Rittenberg. Unlike the case with drugs, the initial amount of tissue or tissue protein is not zero because daily synthesis offsets daily elimination. In this case, the model is also said to approach a steady state with exponential or logarithmic kinetics. Constituents that change in this manner are said to have a biological half-life.A practical application of the plateau principle is that most people have experienced ""plateauing"" during regimens for weight management or training for sports. After a few weeks of progress, one seems unable to continue gaining in ability or losing weight. This outcome results from the same underlying quantitative model. This entry will describe the popular concepts as well as development of the plateau principle as a scientific, mathematical model.In the sciences, the broadest application of the plateau principle is creating realistic time signatures for change in kinetic models (see Mathematical model). One example of this principle is the long time required to effectively change human body composition. Theoretical studies have shown that many months of consistent physical training and food restriction are needed to bring about permanent weight stability in people who were previously overweight.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report