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DNA - Hermantown
DNA - Hermantown

... How does DNA replicate? How does it make a copy of itself? ...
DNA notes 2015 - OG
DNA notes 2015 - OG

... - Important during meiosis & mitosis – DNA gets passed on to daughter cells • DNA polymerase adds nucleotides to the parent strands and checks the strand for errors • Each double helix now has 1 old strand & 1 new strand •This is called SEMI-CONSERVATIVE • If the original strand of DNA is ATTGCACT, ...
BASIC DNA
BASIC DNA

... • DNA Polymorphism (“many forms”) – Regions of DNA which differ from person to person • Locus (plural = loci) – Site or location on a chromosome • Allele – Different variants which can exist at a locus • DNA Profile – The combination of alleles for an individual ...
Comprehension Questions
Comprehension Questions

... 19. What is the expected rate of nucleotide differences? How many nucleotides difference can be expected in a 600bp segment of DNA? What is the significance of this information? ...
unit iv - dna & cell division
unit iv - dna & cell division

DNA and RNA
DNA and RNA

... Based on his results, Griffith hypothesized that when the harmless and heat-killed bacteria where mixed, some factor was exchanged between them, making the live harmless bacteria deadly. Transformation – process in which one strain of bacteria is changed by the gene(s) of another bacteria ...
classes of mutation
classes of mutation

... A condition caused by mutations in one or more genes is called a genetic disorder. Some mutations alter a gene's DNA base sequence but do not change the function of the protein made by the gene. One study on the comparison of genes between different species of Drosophila suggests that if a mutation ...
Chapter 12: Genetic Engineering
Chapter 12: Genetic Engineering

...  Although individuals may have identical genes, there may be different numbers of repeats between these genes  The more repeats, the longer the junk DNA between genes Restriction enzymes are used to cut DNA into fragments The DNA fragments are carefully injected into a gel  The fragments are sepa ...
Activity 10
Activity 10

... supports their hypothesis and the class as a whole can solve the crime. Note: If creating your own DNA strands for this activity seems too tedious, there are some activities on the web which provide downloadable DNA strands that might be adapted to this activity or allow for more efficient creation ...
The ATM repair pathway inhibits RNA polymerase I transcription in
The ATM repair pathway inhibits RNA polymerase I transcription in

Is a Step Backwards in S-Phase-Targeted Chemotherapy a Step Forward?
Is a Step Backwards in S-Phase-Targeted Chemotherapy a Step Forward?

... firing of replication origins but did not significantly affect the progression of replication forks from origins fired prior to drug treatment as is the case for conventional S phase–acting chemotherapeutics, indicating PHA-767491 exerts its effects at the replication initiation stage. To date, this ...
7.1 DNA Introduction
7.1 DNA Introduction

Document
Document

...  Elements of complementary nature spontaneously “stick” together.  This “complementary-attraction-principle” seems to pervade many aspects of life (both molecular and higher levels). ...
chapt17_lecture_anim_ppt
chapt17_lecture_anim_ppt

... • Fundamentally new method for DNA sequencing – DNA is cleaved into smaller pieces – Both ends are ligated to adapters that are complementary to specific primers – DNA fragments are injected into a flow cell – Each of 7 channels contains a solid substrate with primers that complement the ligated en ...
Name Date Class
Name Date Class

... Oswald Theodore Avery and his colleagues Colin MacLeod and Maclyn McCarty, continuing the work done by Griffith, identified the DNA molecule as the source of genetic information. Eight years later, experiments conducted by Alfred Hershey and Martha Chase clearly confirmed that DNA was indeed the sou ...
TrueAllele Report
TrueAllele Report

... A definite genotype can be determined when a person’s DNA produces unambiguous data. However, when the data signals are less definitive, or when there are multiple contributors to the evidence, uncertainty arises. This uncertainty is expressed in the resulting genotype, which may describe different ...
DNA, RNA, and Protein Synthesis Notes
DNA, RNA, and Protein Synthesis Notes

... Hint: You should end up with two complete DNA strands when you are done. ...
Molecular Genetics
Molecular Genetics

... molecule into 2 strands  Each strand serves as a template for making a new complementary strand  The process is SEMI CONSERVATIVE = each new molecule consists of one new and one old strand of DNA  the sequence of bases gets preserved ...
adjuvants - Ac-11
adjuvants - Ac-11

2013 DNA/Replication Notes
2013 DNA/Replication Notes

... a double helix with antiparallel strands, and, (3) had the phosphate backbone on the outside (thus the bases of DNA, which are the "code" for inheritance, were on the inside of the helix). Calculations from the photograph also provided crucial parameters for the size of the helix and its structure, ...
Teacher Notes - 3D Molecular Designs
Teacher Notes - 3D Molecular Designs

Mitochondrial DNA - MrsWrightsSciencePage
Mitochondrial DNA - MrsWrightsSciencePage

... Endosymbiotic Theory ...
Genetics DNA and Genetics
Genetics DNA and Genetics

... directions. Genes provide the directions for a cell to put together molecules that express traits, such as eye color or seed shape. Recall that a gene is a section of a chromosome. Chromosomes are made of proteins and deoxyribonucleic (dee AHK sih ri boh noo klee ihk) acid, or DNA. DNA is an organis ...
m5zn_7de32f5a588b6c7
m5zn_7de32f5a588b6c7

... DNA replication is the process of copying a DNA molecule. Replication is semiconservative, with each strand of the original double helix (parental molecule) serving as a template (mold or model) for a new strand in a daughter molecule. This process consists of: • Unwinding (initiation): old strands ...
Chapter 9. Pg 189 DNA: The Genetic Material
Chapter 9. Pg 189 DNA: The Genetic Material

... move on to the next one if the previous one is correctly paired to its complementary base. If there is a mismatch, then the DNA polymerases can move backwards and make the correction. ...
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DNA repair



DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages (interstrand crosslinks or ICLs).The rate of DNA repair is dependent on many factors, including the cell type, the age of the cell, and the extracellular environment. A cell that has accumulated a large amount of DNA damage, or one that no longer effectively repairs damage incurred to its DNA, can enter one of three possible states: an irreversible state of dormancy, known as senescence cell suicide, also known as apoptosis or programmed cell death unregulated cell division, which can lead to the formation of a tumor that is cancerousThe DNA repair ability of a cell is vital to the integrity of its genome and thus to the normal functionality of that organism. Many genes that were initially shown to influence life span have turned out to be involved in DNA damage repair and protection.
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