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DNA Mutation
DNA Mutation

... chromosome and alter the proteins made by those genes. Conditions caused by a change in the number or structure of chromosomes are known as chromosomal disorders. These changes can occur during the formation of reproductive cells or in early fetal development. Many cancer cells also have changes in ...
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Model of unequal chromosomal crossing over in DNA sequences1
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Carcinomas with DNA Mismatch Repair Deficiency

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Single-Nucleotide Polymorphisms: an overview of the analytical power of SNP's in genomic research and the preliminary results of its application
Single-Nucleotide Polymorphisms: an overview of the analytical power of SNP's in genomic research and the preliminary results of its application

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DNA & RNA
DNA & RNA

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How to play

... a spiral staircase scientists call a double helix. The staircase's steps are built with combinations of 4 base elements. These are A, T, C, G (Adenine, Thymine, Cytosine, Guanine) and the rule is that A always pairs with T, while C always pairs with G. These are also called base pairs and they are b ...
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Microsatellite



A microsatellite is a tract of repetitive DNA in which certain DNA motifs (ranging in length from 2–5 base pairs) are repeated, typically 5-50 times. Microsatellites occur at thousands of locations in the human genome and they are notable for their high mutation rate and high diversity in the population. Microsatellites and their longer cousins, the minisatellites, together are classified as VNTR (variable number of tandem repeats) DNA. The name ""satellite"" refers to the early observation that centrifugation of genomic DNA in a test tube separates a prominent layer of bulk DNA from accompanying ""satellite"" layers of repetitive DNA. Microsatellites are often referred to as short tandem repeats (STRs) by forensic geneticists, or as simple sequence repeats (SSRs) by plant geneticists.They are widely used for DNA profiling in kinship analysis and in forensic identification. They are also used in genetic linkage analysis/marker assisted selection to locate a gene or a mutation responsible for a given trait or disease.
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