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Watson - Crick model explains
... molecular mass could show very different sedimentation rates – Fast sedimenting DNA had more compact shape because molecule was twisted (supercoiled) upon itself (rubber band, phone cord) – Occupies less volume; moves more rapidly in response to centrifugal force or electrical field ...
... molecular mass could show very different sedimentation rates – Fast sedimenting DNA had more compact shape because molecule was twisted (supercoiled) upon itself (rubber band, phone cord) – Occupies less volume; moves more rapidly in response to centrifugal force or electrical field ...
DNA/mRNA Model Activity
... 12. 5’ ends 13. 3’ ends 14. 5’ cap (HINT: it is made of GTP called guanine triphosphate) 15. Poly A tail 16. Exons with codons (mRNA coding region) 17. UTR’s (untranslational regions) ...
... 12. 5’ ends 13. 3’ ends 14. 5’ cap (HINT: it is made of GTP called guanine triphosphate) 15. Poly A tail 16. Exons with codons (mRNA coding region) 17. UTR’s (untranslational regions) ...
RNA and Protein Synthesis
... – Sickle cell disease is a disorder associated with changes in the shape of red blood cells. Normal red blood cells are round. Sickle cells appear long and pointed. – Sickle cell disease is caused by a point mutation in one of the polypeptides found in hemoglobin, the blood’s principal oxygencarryin ...
... – Sickle cell disease is a disorder associated with changes in the shape of red blood cells. Normal red blood cells are round. Sickle cells appear long and pointed. – Sickle cell disease is caused by a point mutation in one of the polypeptides found in hemoglobin, the blood’s principal oxygencarryin ...
SNPs - PBGworks
... The two strands of DNA are antiparallel; they run in opposite directions. The carbon atoms of the deoxyribose sugars are numbered for orientation. http://en.wikipedia.org/wiki/Image:DNA_chemical_structure.png ...
... The two strands of DNA are antiparallel; they run in opposite directions. The carbon atoms of the deoxyribose sugars are numbered for orientation. http://en.wikipedia.org/wiki/Image:DNA_chemical_structure.png ...
DNA! - Chapter 10
... 1. Topisomerase unwinds DNA and then Helicase breaks H-bonds 2. Primase creates RNA primers in spaced intervals 3. Polymerase slides along the leading strand in the 3’ to 5’ direction synthesizing the matching Okazaki fragments in the 5’ to 3’ direction 4. The RNA primers are degraded by RNase H and ...
... 1. Topisomerase unwinds DNA and then Helicase breaks H-bonds 2. Primase creates RNA primers in spaced intervals 3. Polymerase slides along the leading strand in the 3’ to 5’ direction synthesizing the matching Okazaki fragments in the 5’ to 3’ direction 4. The RNA primers are degraded by RNase H and ...
Core Concepts in Genetics - University of Colorado Boulder
... foreign pollen, or be easily capable of such protection. 3. The hybrids and their offspring ...
... foreign pollen, or be easily capable of such protection. 3. The hybrids and their offspring ...
Nucleic Acids Powerpoint
... The enzyme helicase unwinds several sections of parent DNA At each open DNA section, called a replication fork, DNA polymerase catalyzes the formation of 5’-3’ester bonds of the leading strand The lagging strand, which grows in the 3’-5’ direction, is synthesized in short sections called Okazaki fra ...
... The enzyme helicase unwinds several sections of parent DNA At each open DNA section, called a replication fork, DNA polymerase catalyzes the formation of 5’-3’ester bonds of the leading strand The lagging strand, which grows in the 3’-5’ direction, is synthesized in short sections called Okazaki fra ...
DNA repair
... – The bacteria become highly sensitive to UV (gets damaged by it). – UvrA-recognizes the damaged DNA and recruits UvrB and UvrC to the damaged area. – UvrB and UvrC then cleave the 3’ and 5’ sides of the damaged site. – UvrABC comples is called exinuclease (excise an oligonucleotide). – Helicase is ...
... – The bacteria become highly sensitive to UV (gets damaged by it). – UvrA-recognizes the damaged DNA and recruits UvrB and UvrC to the damaged area. – UvrB and UvrC then cleave the 3’ and 5’ sides of the damaged site. – UvrABC comples is called exinuclease (excise an oligonucleotide). – Helicase is ...
DNA Nanotweezers Studied with a Coarse
... over a range of concentrations. The third basic transition is hairpin formation, in which self-complementary strands bind to themselves to form a stem and hairpin loop. Our model underestimates Tm relative to the nearest-neighbor model by approximately 3 K (less than 1% of the absolute temperature), ...
... over a range of concentrations. The third basic transition is hairpin formation, in which self-complementary strands bind to themselves to form a stem and hairpin loop. Our model underestimates Tm relative to the nearest-neighbor model by approximately 3 K (less than 1% of the absolute temperature), ...
Regulation of Transcription
... maltose activator protein and the inducer would be the sugar maltose. ...
... maltose activator protein and the inducer would be the sugar maltose. ...
Document
... usually corresponding to a single mRNA that carries the information needed for constructing a protein. Amazingly only 3% of DNA contains genes, the rest is inactive. • “Messenger” Ribonucleic Acid(mRNA) copies the genetic material off of a DNA strand and transports it form the nucleus to the cytopla ...
... usually corresponding to a single mRNA that carries the information needed for constructing a protein. Amazingly only 3% of DNA contains genes, the rest is inactive. • “Messenger” Ribonucleic Acid(mRNA) copies the genetic material off of a DNA strand and transports it form the nucleus to the cytopla ...
Chapter 12 Slide show - local.brookings.k12.sd.us
... Enzyme binds to places with specific DNA PROMOTERS sequences called _______________. RNA POLYMERASE PROMOTERS tell _________________ where to start. Signals at the end of the gene code cause transcription to _____ stop . http://images2.clinicaltools.com/images/gene/dna_versus_rna_reversed.jpg ...
... Enzyme binds to places with specific DNA PROMOTERS sequences called _______________. RNA POLYMERASE PROMOTERS tell _________________ where to start. Signals at the end of the gene code cause transcription to _____ stop . http://images2.clinicaltools.com/images/gene/dna_versus_rna_reversed.jpg ...
ch. 16 Molecular Basis of Inheritance-2009
... – Adenine forms two hydrogen bonds only with thymine – Guanine forms three hydrogen bonds only with cytosine. – This finding explained Chargaff’s rules. Fig. 16.6 Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings ...
... – Adenine forms two hydrogen bonds only with thymine – Guanine forms three hydrogen bonds only with cytosine. – This finding explained Chargaff’s rules. Fig. 16.6 Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings ...
DNA Databases - Glasgow Science Centre
... As of 2008, the law differs between Scotland and England and Wales. In Scotland, DNA samples and records must be destroyed should a suspect be found innocent or re leased without charge. This is not the case in England or Wales however, where samples are retained even if a suspect is acqu ...
... As of 2008, the law differs between Scotland and England and Wales. In Scotland, DNA samples and records must be destroyed should a suspect be found innocent or re leased without charge. This is not the case in England or Wales however, where samples are retained even if a suspect is acqu ...
Molecular Basis of Inheritance
... remain in the supernatant while bacteria form a pellet The supernatant is radioactive, but the pellet is not. ...
... remain in the supernatant while bacteria form a pellet The supernatant is radioactive, but the pellet is not. ...
No Slide Title
... • Unrepaired DNA damages can lead to deletion of one or more bases pairs (in the case of depurination) or to a base-pair substitution in the daughter DNA chain (in the case of deamination and alkylation) ...
... • Unrepaired DNA damages can lead to deletion of one or more bases pairs (in the case of depurination) or to a base-pair substitution in the daughter DNA chain (in the case of deamination and alkylation) ...
Chapter 1 A View of Life
... 4. tRNA molecules are approximately 70 nucleotides long, with some generic sections and some unique sections 5. The nucleotide chain is folded back upon itself to form 3 or more loops with unpaired nucleotides exposed C. The components of the translational machinery come together at the ribosomes Ri ...
... 4. tRNA molecules are approximately 70 nucleotides long, with some generic sections and some unique sections 5. The nucleotide chain is folded back upon itself to form 3 or more loops with unpaired nucleotides exposed C. The components of the translational machinery come together at the ribosomes Ri ...
Overview of DNA Purification for Nucleic Acid
... is very low, such as for the analysis of single cells or bacteria that have been concentrated by immunomagnetic separation, the DNA may actually be lost in the purification step (31). However, most environmental and clinical samples may contain compounds that are potent inhibitors of the enzymes use ...
... is very low, such as for the analysis of single cells or bacteria that have been concentrated by immunomagnetic separation, the DNA may actually be lost in the purification step (31). However, most environmental and clinical samples may contain compounds that are potent inhibitors of the enzymes use ...
DNA’s Discovery and Structure
... - only one of the DNA strands contains the protein recipe - the strand with the recipe is the template strand - the strand without the recipe is the non-template strand - it is not copied ...
... - only one of the DNA strands contains the protein recipe - the strand with the recipe is the template strand - the strand without the recipe is the non-template strand - it is not copied ...
Unit-IV GENETIC ENGINEERING
... been accepted in most courts in the United States. DNA fingerprinting is generally regarded as a reliable forensic tool when properly done, but some scientists have called for wider sampling of human DNA to insure that the segments analyzed are indeed highly variable for all ethnic and racial grou ...
... been accepted in most courts in the United States. DNA fingerprinting is generally regarded as a reliable forensic tool when properly done, but some scientists have called for wider sampling of human DNA to insure that the segments analyzed are indeed highly variable for all ethnic and racial grou ...
DNA
... reaction similar to formation of peptide bond - bases are bound to sugar by glycosidic bond Picture of DNA ...
... reaction similar to formation of peptide bond - bases are bound to sugar by glycosidic bond Picture of DNA ...
DNArepl3
... Yeast ORC specifically binds to replication origins in an ATP dependent manner and has been shown to possess ATPase activity. CDC6/Cdc18 : An essential factor for the assembly of the prereplicative complexes that co-operates with Cdt1 to load MCM2-7 Proteolyzed in yeasts or exported out of the nucle ...
... Yeast ORC specifically binds to replication origins in an ATP dependent manner and has been shown to possess ATPase activity. CDC6/Cdc18 : An essential factor for the assembly of the prereplicative complexes that co-operates with Cdt1 to load MCM2-7 Proteolyzed in yeasts or exported out of the nucle ...
Chapter 10 #1
... • The bases attract each other because of hydrogen bonds. • Hydrogen bonds are weak but there are millions and millions of them in a single molecule of DNA. • (The bonds between cytosine and guanine are shown here.) ...
... • The bases attract each other because of hydrogen bonds. • Hydrogen bonds are weak but there are millions and millions of them in a single molecule of DNA. • (The bonds between cytosine and guanine are shown here.) ...
Second Strand cDNA Synthesis Kit
... 2. Collect all components by a brief centrifugation. Incubate the reaction at 16°C for 2.5 hours. 3. Chill on ice. The newly generated double-stranded cDNA is ready for immediate downstream applications, or for long-term storage at -20oC. 4. The quantity and size distribution of the synthesized prod ...
... 2. Collect all components by a brief centrifugation. Incubate the reaction at 16°C for 2.5 hours. 3. Chill on ice. The newly generated double-stranded cDNA is ready for immediate downstream applications, or for long-term storage at -20oC. 4. The quantity and size distribution of the synthesized prod ...
Electrophoretic stretching of DNA molecules using microscale T
... 共Ref. 19兲兴. The molecule in Fig. 4 reaches a final steady state extension which is 94% of the full contour length. Our DNA trapping and stretching device has several advantages over other methods. Electric fields are much easier to apply and control and their connections have smaller lagtimes than h ...
... 共Ref. 19兲兴. The molecule in Fig. 4 reaches a final steady state extension which is 94% of the full contour length. Our DNA trapping and stretching device has several advantages over other methods. Electric fields are much easier to apply and control and their connections have smaller lagtimes than h ...
DNA nanotechnology
![](https://en.wikipedia.org/wiki/Special:FilePath/DNA_tetrahedron_white.png?width=300)
DNA nanotechnology is the design and manufacture of artificial nucleic acid structures for technological uses. In this field, nucleic acids are used as non-biological engineering materials for nanotechnology rather than as the carriers of genetic information in living cells. Researchers in the field have created static structures such as two- and three-dimensional crystal lattices, nanotubes, polyhedra, and arbitrary shapes, as well as functional devices such as molecular machines and DNA computers. The field is beginning to be used as a tool to solve basic science problems in structural biology and biophysics, including applications in crystallography and spectroscopy for protein structure determination. Potential applications in molecular scale electronics and nanomedicine are also being investigated.The conceptual foundation for DNA nanotechnology was first laid out by Nadrian Seeman in the early 1980s, and the field began to attract widespread interest in the mid-2000s. This use of nucleic acids is enabled by their strict base pairing rules, which cause only portions of strands with complementary base sequences to bind together to form strong, rigid double helix structures. This allows for the rational design of base sequences that will selectively assemble to form complex target structures with precisely controlled nanoscale features. A number of assembly methods are used to make these structures, including tile-based structures that assemble from smaller structures, folding structures using the DNA origami method, and dynamically reconfigurable structures using strand displacement techniques. While the field's name specifically references DNA, the same principles have been used with other types of nucleic acids as well, leading to the occasional use of the alternative name nucleic acid nanotechnology.