HST-150/151 Mid
... No, because reduction of plasma LDL with statins depends upon an intact feedback mechanism in the hepatocyte: Inhibition of cholesterol synthesis decreases intracellular cholesterol; this upregulates LDL-receptor synthesis, which takes up LDL from plasma and establishes a lower steady-state. This ca ...
... No, because reduction of plasma LDL with statins depends upon an intact feedback mechanism in the hepatocyte: Inhibition of cholesterol synthesis decreases intracellular cholesterol; this upregulates LDL-receptor synthesis, which takes up LDL from plasma and establishes a lower steady-state. This ca ...
1 hour 05 Minutes
... Q.33 Although prescribed by a careless physician for ulcerative colitis but it is hardly useful; the drug is: a) Prednisone. b) Metho trexate. c) Infliximab. d) Azathioprine. e) Loratadine. Q.34 A 65 year old lady who is a known patient of Parkinsonism is also on anticancer therapy; but to avoid th ...
... Q.33 Although prescribed by a careless physician for ulcerative colitis but it is hardly useful; the drug is: a) Prednisone. b) Metho trexate. c) Infliximab. d) Azathioprine. e) Loratadine. Q.34 A 65 year old lady who is a known patient of Parkinsonism is also on anticancer therapy; but to avoid th ...
ECSTASY AKA MDMA MDMA is a “mood elevator”
... drug can often take on great importance in people’s lives, and some people become rather compulsive in their use. Taken too frequently, however, MDMA loses its special effect. MDMA releases the brain chemical serotonin, elevating mood and acting as a short term ...
... drug can often take on great importance in people’s lives, and some people become rather compulsive in their use. Taken too frequently, however, MDMA loses its special effect. MDMA releases the brain chemical serotonin, elevating mood and acting as a short term ...
Alcohol and Drugs - The Evergreen State College
... Cocaine is a powerful stimulant, which means it might keep you wired, but not without major risks. Cocaine causes your blood vessels to constrict immediately, increasing your heart rate, blood pressure and body temperature.12 At first, this may make you sweaty and shaky, but seizures, cardiac arrest ...
... Cocaine is a powerful stimulant, which means it might keep you wired, but not without major risks. Cocaine causes your blood vessels to constrict immediately, increasing your heart rate, blood pressure and body temperature.12 At first, this may make you sweaty and shaky, but seizures, cardiac arrest ...
Snímek 1
... Ultrarapid metabolizers may break down some drugs (e.g. some antidepressants) so quickly that the drug does not need to help at usual doses. They may also need a lower dose of a drug, in the case where a drug is metabolized in active metabolites (e.g. in some opioid analgesics) Poor metabolizers hav ...
... Ultrarapid metabolizers may break down some drugs (e.g. some antidepressants) so quickly that the drug does not need to help at usual doses. They may also need a lower dose of a drug, in the case where a drug is metabolized in active metabolites (e.g. in some opioid analgesics) Poor metabolizers hav ...
Snímek 1
... Ultrarapid metabolizers may break down some drugs (e.g. some antidepressants) so quickly that the drug does not need to help at usual doses. They may also need a lower dose of a drug, in the case where a drug is metabolized in active metabolites (e.g. in some opioid analgesics) Poor metabolizers hav ...
... Ultrarapid metabolizers may break down some drugs (e.g. some antidepressants) so quickly that the drug does not need to help at usual doses. They may also need a lower dose of a drug, in the case where a drug is metabolized in active metabolites (e.g. in some opioid analgesics) Poor metabolizers hav ...
1 ADDICTION, WITHDRAWAL, AND AGGRESSIVENESS IN
... for e.g.., Yaba is a stimulating mixture of methamphetamine and caffeine which is found in Southeast Asia. Overdose can become deadly because of the increase of blood pressure and other heart rhythm disorders (Iftene, 2007); d) MDMA or Ecstasy is a stimulating and energizing drug, yet it was never m ...
... for e.g.., Yaba is a stimulating mixture of methamphetamine and caffeine which is found in Southeast Asia. Overdose can become deadly because of the increase of blood pressure and other heart rhythm disorders (Iftene, 2007); d) MDMA or Ecstasy is a stimulating and energizing drug, yet it was never m ...
Theories of addiction: Causes and maintenance of addiction
... The mesolimbic-fronto cortical dopamine system (containing the mesolimbic and mesocortical dopamine systems) is regarded as a critical pathway in brain reward (Nutt, 1997; Wise, 1996). Dopamine has been implicated in the reinforcing effects of alcohol, with alcohol use resulting in the direct stimul ...
... The mesolimbic-fronto cortical dopamine system (containing the mesolimbic and mesocortical dopamine systems) is regarded as a critical pathway in brain reward (Nutt, 1997; Wise, 1996). Dopamine has been implicated in the reinforcing effects of alcohol, with alcohol use resulting in the direct stimul ...
Pharmacology 3a – Cholinomimetics
... Low dose o Enhanced muscarinic activity. o Excitation of CNS & possible convulsions (seizures) Moderate dose o Further enhancement of muscarinic activity o Increased transmission at ALL (PNS and SNS) autonomic ganglia High dose (toxic) o Depolarising block at autonomic ganglia. o Unconsciousne ...
... Low dose o Enhanced muscarinic activity. o Excitation of CNS & possible convulsions (seizures) Moderate dose o Further enhancement of muscarinic activity o Increased transmission at ALL (PNS and SNS) autonomic ganglia High dose (toxic) o Depolarising block at autonomic ganglia. o Unconsciousne ...
FOOD AND DRUG ADMINISTRATION November 6,200Q
... Although the risk of hemorrhagic stroke is very low, FDA recommends that consumers not use any products that contain phenylpropanolamine. FDA’s Nonprescription Drugs Advisory Committee (NDAC) recently discussed this study and other information on phenyIpropanokuninc. NDAC determined that thrxe is an ...
... Although the risk of hemorrhagic stroke is very low, FDA recommends that consumers not use any products that contain phenylpropanolamine. FDA’s Nonprescription Drugs Advisory Committee (NDAC) recently discussed this study and other information on phenyIpropanokuninc. NDAC determined that thrxe is an ...
File
... • Metoclopramide accomplishes this through inhibition of dopamine in the CTZ. • Antidopaminergic side effects, including extrapyramidal symptoms, limit long-term high-dose use. • Metoclopramide was previously used for the treatment of GERD. However, due to the adverse effect profile and the availabi ...
... • Metoclopramide accomplishes this through inhibition of dopamine in the CTZ. • Antidopaminergic side effects, including extrapyramidal symptoms, limit long-term high-dose use. • Metoclopramide was previously used for the treatment of GERD. However, due to the adverse effect profile and the availabi ...
analgesics
... it is a bit less dangerous in the aspect of addiction development (in comparison with morphine) indicated in case of pain of medium intensity in such conditions like other narcotic analgesics. it can cause increasing of blood pressure and tachycardia that’s why it’s not advised to use in case ...
... it is a bit less dangerous in the aspect of addiction development (in comparison with morphine) indicated in case of pain of medium intensity in such conditions like other narcotic analgesics. it can cause increasing of blood pressure and tachycardia that’s why it’s not advised to use in case ...
Stimulants:
... off C Cocaine i U Use (i (in >12 y.o.)) • 11.2% of U.S. population report ever using cocaine (NHSDA 2000) • 1.5% report use within the past year (NHSDA 2000) • 1.9 million (0.7%) report use within the past month (NSDUH 2008) • Most common in 18-25 age group (NHSDA 2000) • 663,000 received treatment ...
... off C Cocaine i U Use (i (in >12 y.o.)) • 11.2% of U.S. population report ever using cocaine (NHSDA 2000) • 1.5% report use within the past year (NHSDA 2000) • 1.9 million (0.7%) report use within the past month (NSDUH 2008) • Most common in 18-25 age group (NHSDA 2000) • 663,000 received treatment ...
Hallucinogens - People Server at UNCW
... • Although neurotoxic doses in non-humans (520 mg/kg twice or more/day for several days) are generally higher than would be typical of human use, people often take several tablets at a time or throughout an night’s binge and a tablet may contain up to 300 mg: 4-5 mg/kg in an average person. ...
... • Although neurotoxic doses in non-humans (520 mg/kg twice or more/day for several days) are generally higher than would be typical of human use, people often take several tablets at a time or throughout an night’s binge and a tablet may contain up to 300 mg: 4-5 mg/kg in an average person. ...
Psychiatric Drugs
... augmentation strategies have been tested with various pharmacological agents, there are few controlled studies published." Ex: Seroquel (quetiapine), Abilify (aripiprazole) ...
... augmentation strategies have been tested with various pharmacological agents, there are few controlled studies published." Ex: Seroquel (quetiapine), Abilify (aripiprazole) ...
Individualizing Antidepressant Therapy Individualizing
... Well tolerated More safety studies during pregnancy More safety studies after MI or stroke Better for atypical symptoms generic ...
... Well tolerated More safety studies during pregnancy More safety studies after MI or stroke Better for atypical symptoms generic ...
BETAHISTINE HYDROCHL ORIDE
... It is now known whether betahistine is excreted in human breast milk. The benefits of the drug to the mother should be weighed against the potential risk to the baby when considering betahistine treatment. Children The safety and efficacy of betahistine in pediatric patients less than 18 years old h ...
... It is now known whether betahistine is excreted in human breast milk. The benefits of the drug to the mother should be weighed against the potential risk to the baby when considering betahistine treatment. Children The safety and efficacy of betahistine in pediatric patients less than 18 years old h ...
Acute poisonings with substance of abuse
... 39 packets were excreted on the first day, 10 – on the second day, 3 – at the third day X-ray 3 days later revealed foreign bodies in the gastrointestinal tract (“double condom’’ sign) Because of customs officers demand the patient was transferred to the Hospital of Prison, despite staff objection. ...
... 39 packets were excreted on the first day, 10 – on the second day, 3 – at the third day X-ray 3 days later revealed foreign bodies in the gastrointestinal tract (“double condom’’ sign) Because of customs officers demand the patient was transferred to the Hospital of Prison, despite staff objection. ...
Ma huang: All natural but not always innocuous
... Herbal supplements are becoming increasingly popular and can be found everywhere from malls and discount stores to mail-order warehouses. Although many herbs have a low potential for adverse effects, some can cause lifethreatening reactions. Many people assume that if something is "natural," the sub ...
... Herbal supplements are becoming increasingly popular and can be found everywhere from malls and discount stores to mail-order warehouses. Although many herbs have a low potential for adverse effects, some can cause lifethreatening reactions. Many people assume that if something is "natural," the sub ...
Drugs and the Synapse
... Drugs and the Synapse • Amphetamines stimulate dopamine synapses by increasing the release of dopamine from the presynaptic terminal. • Cocaine blocks the reuptake of dopamine, norepinephrine, and serotonin. • Methylphenidate (Ritalin) also blocks the reuptake of dopamine but in a more gradual and ...
... Drugs and the Synapse • Amphetamines stimulate dopamine synapses by increasing the release of dopamine from the presynaptic terminal. • Cocaine blocks the reuptake of dopamine, norepinephrine, and serotonin. • Methylphenidate (Ritalin) also blocks the reuptake of dopamine but in a more gradual and ...
Drugs: Antagonists, agonists, and reuptake inhibitors Drugs—why
... dopamine receptors. Antagonists can prevent or reverse the actions of dopamine by keeping dopamine from attaching to receptors. Dopamine antagonists are traditionally used to treat schizophrenia and related mental disorders. A person with schizophrenia may have an overactive dopamine system. Dopamin ...
... dopamine receptors. Antagonists can prevent or reverse the actions of dopamine by keeping dopamine from attaching to receptors. Dopamine antagonists are traditionally used to treat schizophrenia and related mental disorders. A person with schizophrenia may have an overactive dopamine system. Dopamin ...
Detection of drug abuse and misuse using biological samples
... and cheaply manufactured in illicit laboratories and is abused worldwide. The d-isomer is therapeutically used to treat attention deficit hyperactivity disorder and for short-term treatment of obesity; it is considerably more potent than the l-isomer, which is sold over-the-counter as a nasal decong ...
... and cheaply manufactured in illicit laboratories and is abused worldwide. The d-isomer is therapeutically used to treat attention deficit hyperactivity disorder and for short-term treatment of obesity; it is considerably more potent than the l-isomer, which is sold over-the-counter as a nasal decong ...
Nursing 715 Pharmacological Basis of Therapeutics
... First-pass and other pre-systemic metabolism is a very important determinant of oral bioavailibility especially for lipid soluble drugs (see later) ...
... First-pass and other pre-systemic metabolism is a very important determinant of oral bioavailibility especially for lipid soluble drugs (see later) ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.