Recent Trends in Challenges to Forensic Evidence Used in Criminal
... with the goal of mimicking those substances Often marketed as herbal incense, bath salts, jewelry cleaner, or plant food, and have caused significant abuse, addiction, overdoses, and emergency room visits They are labeled “not for human consumption” to mask their intended purpose and avoid Food and ...
... with the goal of mimicking those substances Often marketed as herbal incense, bath salts, jewelry cleaner, or plant food, and have caused significant abuse, addiction, overdoses, and emergency room visits They are labeled “not for human consumption” to mask their intended purpose and avoid Food and ...
Emergency Pharmacology
... we move to phase III Phase III – extended clinical evaluation. Full-scale evaluation on large number of subjects to determine therapeutic effects, side effects and its tolerability and to establish tolerable dose ranges ...
... we move to phase III Phase III – extended clinical evaluation. Full-scale evaluation on large number of subjects to determine therapeutic effects, side effects and its tolerability and to establish tolerable dose ranges ...
Caffeine - Sleep - Centre Londres 94
... At low to moderate doses… • increases ACh synthesis (LTP and memory) • alertness (memory) • ability to concentrate • speeds up reaction time • Anacin – relieves vascular headaches ...
... At low to moderate doses… • increases ACh synthesis (LTP and memory) • alertness (memory) • ability to concentrate • speeds up reaction time • Anacin – relieves vascular headaches ...
Clinical Cases in Toxicology
... lipophilic β-blockers e.g. propanolol, metoprolol, carvedilol, labetalol antipsychotics e.g. quetiapine ...
... lipophilic β-blockers e.g. propanolol, metoprolol, carvedilol, labetalol antipsychotics e.g. quetiapine ...
ADRENERGIC SYSTEM - LEC.2 2008
... 2- NOR- ADRENALINE : 1- it is one of the most commonly used adrenergic agonist drug in therapy .2- it is mainly alpha adrenoceptor agonist , but also affect Beta-1 . Pharmacokinetic : 1- it is given by intravenous infusion to obtained a gradual sustained response . 2- the effect of a single dose wou ...
... 2- NOR- ADRENALINE : 1- it is one of the most commonly used adrenergic agonist drug in therapy .2- it is mainly alpha adrenoceptor agonist , but also affect Beta-1 . Pharmacokinetic : 1- it is given by intravenous infusion to obtained a gradual sustained response . 2- the effect of a single dose wou ...
BIOM 255: Molecular basis of drug action and disease therapy
... • Patients and health providers (e.g., physicians and pharmacists) are partners that seek to optimize drug prescription/dispensing/administration and thereby maximize efficacy and minimize toxicity, thus increasing the “therapeutic window” (between beneficial and toxic effects). • Adherence (complia ...
... • Patients and health providers (e.g., physicians and pharmacists) are partners that seek to optimize drug prescription/dispensing/administration and thereby maximize efficacy and minimize toxicity, thus increasing the “therapeutic window” (between beneficial and toxic effects). • Adherence (complia ...
Substance Use, Addictions and Related Behaviours
... •In Canada, the number of young persons charged with drug posession has tripled over the past decade •Between 1991 and 2005 the percentage of youth reporting selling Cannabis more than doubled •Over 1/3 of students grade 7-9 have binged on alcohol •Over 40% of 15-19 year olds have binged on alcohol ...
... •In Canada, the number of young persons charged with drug posession has tripled over the past decade •Between 1991 and 2005 the percentage of youth reporting selling Cannabis more than doubled •Over 1/3 of students grade 7-9 have binged on alcohol •Over 40% of 15-19 year olds have binged on alcohol ...
indiv_drugs_f10
... Generally, the faster a drug can enter the brain, the more it will be abused ...
... Generally, the faster a drug can enter the brain, the more it will be abused ...
Antidepressant
... Inhibition of MAO - increases the levels of amine neurotransmitters in neurons and increases the levels of neurotransmitters which are released. MAO exists in two forms, A and B which are encoded by separate genes. Both forms of MAO are found mostly in the outer membranes of mitochondria in both neu ...
... Inhibition of MAO - increases the levels of amine neurotransmitters in neurons and increases the levels of neurotransmitters which are released. MAO exists in two forms, A and B which are encoded by separate genes. Both forms of MAO are found mostly in the outer membranes of mitochondria in both neu ...
Drugs Safety in Pregnancy
... dednemmocer ADR gnideecxe esod C/A(Vitamin A Category* )esod dednemmocer ADR gnideecxe esodC/A yrogetaC Vitamin C* )esod dednemmocer ADR gnideecxe esod C/A yrogetaC Vitamin E* )esod dednemmocer ADR gnideecxe esodC/A Vitamin B Category* )esod Vitamin D CategoryC* C yrogetaC Vitamin K* ...
... dednemmocer ADR gnideecxe esod C/A(Vitamin A Category* )esod dednemmocer ADR gnideecxe esodC/A yrogetaC Vitamin C* )esod dednemmocer ADR gnideecxe esod C/A yrogetaC Vitamin E* )esod dednemmocer ADR gnideecxe esodC/A Vitamin B Category* )esod Vitamin D CategoryC* C yrogetaC Vitamin K* ...
Synaptic transmission & antipsychotic drugs
... Less risk of EPS, but other side effects may occur (e.g. blood disorders) ...
... Less risk of EPS, but other side effects may occur (e.g. blood disorders) ...
narcolepsy medications
... Provigil is a wake-promoting medication for treatment of excessive daytime sleepiness. Unlike other stimulant medications, Provigil has a milder and more targeted effect on the central nervous system. In addition, it is the only wakefulness medication available from any pharmacy that does not requir ...
... Provigil is a wake-promoting medication for treatment of excessive daytime sleepiness. Unlike other stimulant medications, Provigil has a milder and more targeted effect on the central nervous system. In addition, it is the only wakefulness medication available from any pharmacy that does not requir ...
Methamphetamine, “Bath Salts,” and other Amphetamine
... models acute methamphetamine exposure directly affects myocyte contractility by inhibition of intracellular calcium release and upregulation of the sodiumcalcium exchanger. Methamphetamine also directly damages myocardium by increasing p53 expression as well as the cardiac Fas- and mitochondriadepen ...
... models acute methamphetamine exposure directly affects myocyte contractility by inhibition of intracellular calcium release and upregulation of the sodiumcalcium exchanger. Methamphetamine also directly damages myocardium by increasing p53 expression as well as the cardiac Fas- and mitochondriadepen ...
FACTORS MODIFYING DRUG EFFECTS
... concentration of endogenous receptor ligand ,alteration in number of functional receptors, change in components distal to receptors. ...
... concentration of endogenous receptor ligand ,alteration in number of functional receptors, change in components distal to receptors. ...
Antimycobacterial drugs
... Indication of 2nd line treatment to the drugs of 1st line. Failure of clinical response There is contraindication for first line drugs. Patient is not tolerating the drugs first line drugs. ...
... Indication of 2nd line treatment to the drugs of 1st line. Failure of clinical response There is contraindication for first line drugs. Patient is not tolerating the drugs first line drugs. ...
adrenergic drugs
... The adrenergic drugs produce pharmacologic effects similar to the effects that occur in the body when the adrenergic nerves and the medulla are stimulated. The primary effects of these drugs occur on the heart, the blood vessels, and the smooth muscles, such as the bronchi. Adrenergic drugs mimic th ...
... The adrenergic drugs produce pharmacologic effects similar to the effects that occur in the body when the adrenergic nerves and the medulla are stimulated. The primary effects of these drugs occur on the heart, the blood vessels, and the smooth muscles, such as the bronchi. Adrenergic drugs mimic th ...
FDA-approved Cholinesterase Inhibitors
... performance in memory and thinking tests in patients who were on the active medication compared with patients taking a placebo (an inactive substance). It should be stressed that the degree of improve-ment was modest, and more than half of the patients showed no improvement at all. Galantamine also ...
... performance in memory and thinking tests in patients who were on the active medication compared with patients taking a placebo (an inactive substance). It should be stressed that the degree of improve-ment was modest, and more than half of the patients showed no improvement at all. Galantamine also ...
GENERAL ANESTHETICS INHALATION ANESTHETICS
... analgesia, and can be used for major surgery w/o any other kinds of drugs - Patches and lollipops available for chronic pain and children’s surgeries, respectively - Related compounds Sufentanil Alfentanil: Ultra-short-acting compound, w/ action rapidly terminated by metabolism Remifentanil: M ...
... analgesia, and can be used for major surgery w/o any other kinds of drugs - Patches and lollipops available for chronic pain and children’s surgeries, respectively - Related compounds Sufentanil Alfentanil: Ultra-short-acting compound, w/ action rapidly terminated by metabolism Remifentanil: M ...
Downers: A New Look at Depressant Drugs
... take away personal power and initiative and freedom, and never give it back. To get it back, you have to take it back. If you’re strung out on tranquilizers or other downer drugs, start now. Don’t put off quitting another day. The world is littered with the wrecks of people who were going to do some ...
... take away personal power and initiative and freedom, and never give it back. To get it back, you have to take it back. If you’re strung out on tranquilizers or other downer drugs, start now. Don’t put off quitting another day. The world is littered with the wrecks of people who were going to do some ...
New Trends in Substance Abuse Youth Substance Abuse
... Marijuana is one of the most underestimated drugs of abuse. It is used for its mildly tranquilizing, mood and perception altering effects. The active ingredient in Marijuana is THC (Delta-9-Tetrahydrocannabinol), but Marijuana contains hundreds of chemicals called “cannabinoids.” The Marijuana on th ...
... Marijuana is one of the most underestimated drugs of abuse. It is used for its mildly tranquilizing, mood and perception altering effects. The active ingredient in Marijuana is THC (Delta-9-Tetrahydrocannabinol), but Marijuana contains hundreds of chemicals called “cannabinoids.” The Marijuana on th ...
Chapter 12, Hallucinogens PowerPoint
... Tryptamines- molecules that resemble the neurotransmitter serotonin that have hallucinogenic properties and can exist naturally in herbs, fungi, and animals Foxy- the synthetic substance chemically named 5-methoxy-N,Ndiisopropyltryptamine is a relatively new hallucinogen and has been used at raves a ...
... Tryptamines- molecules that resemble the neurotransmitter serotonin that have hallucinogenic properties and can exist naturally in herbs, fungi, and animals Foxy- the synthetic substance chemically named 5-methoxy-N,Ndiisopropyltryptamine is a relatively new hallucinogen and has been used at raves a ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.