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Drug of Abuse 6+2 - Drug Testing
Drug of Abuse 6+2 - Drug Testing

... dependency which leads to its abuse. Cocaine is used by smoking, intravenous, intransal or oral administration and excreted in the urine primarily as benzoylecgonine in a short period. Benzoylecgonine has a biological half-life of 5 – 8 hours, which is much longer than that of cocaine ( 0.5 – 1.5 ho ...
Concerta (methylphenidate, controlled release)
Concerta (methylphenidate, controlled release)

... Possible Drug Interactions Concerta should not be taken in combination with a group of antidepressants known as monoamine oxidase inhibitors. The combination may precipitate increases in blood pressure. This and other significant drug interactions reported with Concerta are summarized in the table b ...
HOW TO COMPARE ANTIPSYCHOTIC DRUG DOSES?
HOW TO COMPARE ANTIPSYCHOTIC DRUG DOSES?

... this finding is slightly limited, because most CPZ-equivalent values were calculated from publications in which it was not defined if patients were treated for the main indication of the antipsychotic drug [1]. However, this fact cannot be the only explanation of the big difference between CPZ-equiv ...
Synergistic Interaction between the Two Mechanisms of Action of
Synergistic Interaction between the Two Mechanisms of Action of

... serotonin-noradrenaline reuptake inhibitors) are among the first-line treatment options for chronic pain. These drugs are generally tolerated relatively well. However, analgesic efficacy of such drugs is often not satisfactory (Fishbain, 2000). Opioids also play an important role in the treatment of ...
Print PDF - CiplaMed
Print PDF - CiplaMed

... cardiolipin, a phospholipid component of the inner mitochondrial membrane. The mechanism for this is unknown, but data suggest that citicoline inhibits enzymatic hydrolysis of cardiolipin by phospholipase A2. Citicoline avoids, reduces or reverses the effects of ischaemia and/or hypoxia in the major ...
Ref: Choudhury et al
Ref: Choudhury et al

... release of GPT and AP in the serum. ...
Treatment of poisoning caused by β
Treatment of poisoning caused by β

... affect lypolysis and may have effects on cardiac inotropy. Beta-receptor complexes are subject to genetic polymorphisms that may result in variable patient responses.4 Some β-blockers have relative specificity for different β-subreceptors, and some agents may antagonize α-receptors. Some β-blockers h ...
Obesity - Moodle Lille 2
Obesity - Moodle Lille 2

... CardioV outcomes ? SAFETY ...
AWOtherapeutics
AWOtherapeutics

... Anti-IgE • Anti-IgE monoclonal antibody : Omalizumab (Xolair) • Omalizumab inhibits the binding to the high-affinity IgE receptor and inhibit mediator release from basophils and mast cells . • Injection every 2-4 weeks . • For patients with severe persistent allergic asthma despite max therapy –ie s ...
Benzodiazepines
Benzodiazepines

...  Chemical structure is the fusion of a benzene ring and a diazepine ring  Central nervous system depressants that are commonly known as tranquilizers, sedatives, or anxiolytics  Due to the sedative effects they produce, they are often used as “date rape” drugs  Approximately 2,000 benzodiazepine ...
OPIATE ANALGESICS AND ANTAGONISTS
OPIATE ANALGESICS AND ANTAGONISTS

... depressant effect of opiates, and its mechanism of action at receptor level is unclear – Chemical modification (Codiene and Pholcodiene ) the antitussive effect can occur at sub- analgesic dose. ...
problem amphetamine and methamphetamine use in
problem amphetamine and methamphetamine use in

... amphetamines, cocaine, ecstasy, piperazines or new stimulant drugs such as mephedrone. Finally, Europe is an important producer of amphetamines with several countries reporting illicit production facilities on their territory. The provision of care for those with amphetamines problems is another are ...
Is cannabis addictive?
Is cannabis addictive?

... Can you get addicted to cannabis? At one time, it was believed that cannabis didn’t have any addictive qualities. Even now, individuals still believe in the casual nature of marijuana. However, extensive research has highlighted just how addictive the substance can be, especially if it is used regul ...
nclex study information
nclex study information

... The typical symptoms of SAD include depression, lack of energy, increased need for sleep, a craving for sweets and weight gain. Symptoms begin in the fall, peak in the winter and usually resolve in the spring. Some individuals experience great bursts of energy and creativity in the spring or early s ...
Illicit Drugs: What the Primary Provider Needs to Know
Illicit Drugs: What the Primary Provider Needs to Know

... pleasure we have when we perform an action that satisfies a need or fulfills a desire. • This flooding causes a reduction in the natural capacity to produce dopamine in the reward system is reduced, but the need persists and the drug seems to be the only way to fulfill it. http://www.health.harvard. ...
Use of nonsteroidal antiinflammatory drugs in dental practice. A review
Use of nonsteroidal antiinflammatory drugs in dental practice. A review

... Although the results of the studies published in the literature are conflicting, it has been suggested that the pharmacological treatment of postoperative pain should begin before surgery and extend to the immediate postoperative period (12). ...
Pharmacokinetics in pregnancy
Pharmacokinetics in pregnancy

... intervals. In this case plasma concentrations rise over the course of approximately three half-lives to ¯uctuate around an average steady state concentration (Css) determined by the daily dose (D) and the clearance of the drug: Css ˆ D/Cls. Fluctuation of the plasma concentration around this level i ...
Atropine
Atropine

... second before inducing flaccid paralysis, but fascilations are not prominent in well anaesthezed patients. The action of SCh develops very rapidly. Apnoea occurs within 45–90 sec, but lasts only 2–5 min and recovery is rapid. Autonomic ganglia. Competitive blockers can produce some degree of ganglio ...
Adrenergic_antagonists
Adrenergic_antagonists

... Some of the β antagonist produce some action of β agonist e.g. Pindolol & Labetalol…, so, they are less dangerous when given to patients with ...
Targets and the Renin Angiotensin Aldosterone System
Targets and the Renin Angiotensin Aldosterone System

... Bradykinin‐specific treatment may decrease  ...
“CRIME SCENE INVESTIGATION” AT AN ANESTHETIC COCKTAIL PARTY WITH ATRIOVENTRICULAR DISSOCIATION c
“CRIME SCENE INVESTIGATION” AT AN ANESTHETIC COCKTAIL PARTY WITH ATRIOVENTRICULAR DISSOCIATION c

... monophosphate, and thus decreases the heart rate. Furthermore, by blocking competitively H2-receptors, free histamine molecules can now activate more H1receptors leading to a G-protein- mediated rise in calcium decreasing cardiac dromotropy. Extremely rare cardiovascular side effects are reported to ...
Grapefruit Seed extract
Grapefruit Seed extract

... The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. Please be sure to consult your physician before taking this or any other product. Consult your physician for any health problems. ...
Outpatient prescriptions practice and writing quality in a paediatric
Outpatient prescriptions practice and writing quality in a paediatric

... In our study the number of errors more than doubled between 2005 and 2010. One third of such errors were caused by changes in marketed medicines, some being withdrawn or having changed their trade name. The increase could also be due to the fast turnover of junior physicians, to their more important ...
Restoril™ (temazepam) Capsules USP Rx only DESCRIPTION
Restoril™ (temazepam) Capsules USP Rx only DESCRIPTION

... insomnia should only be made after the patient has been carefully evaluated. The failure of insomnia to remit after 7 to 10 days of treatment may indicate the presence of a primary psychiatric and/or medical illness that should be evaluated. Worsening of insomnia may be the consequence of an unrecog ...
OTC Pain Relievers: Which One is Right?
OTC Pain Relievers: Which One is Right?

... • What it does: Aspirin relieves pain and reduces inflammation. • Side effects: Aspirin can irritate the stomach. Taking it with food or taking a pill with a buffered coating can reduce irritation, but coated pills may take longer to be effective. • Do not take aspirin if you have ulcers, asthma, un ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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