Sustained Release Drug Delivery System Potential
... Pharmaceutical invention and research are increasingly focusing on delivery systems which enhance desirable therapeutic objectives while minimizing side effects. Oral drug delivery system represents one of the frontier areas of controlled drug delivery system. Such a dosage forms having a major adva ...
... Pharmaceutical invention and research are increasingly focusing on delivery systems which enhance desirable therapeutic objectives while minimizing side effects. Oral drug delivery system represents one of the frontier areas of controlled drug delivery system. Such a dosage forms having a major adva ...
Central nervous system (including peripheral analgesics)
... Children and teenagers should not use this drug if they have recovered, or are recovering, from flu or chickenpox because they may develop Reye’s syndrome, a serious condition associated with the use of aspirin and salicylates.5,6,9 Reye’s syndrome occurs usually after a viral infection such as chic ...
... Children and teenagers should not use this drug if they have recovered, or are recovering, from flu or chickenpox because they may develop Reye’s syndrome, a serious condition associated with the use of aspirin and salicylates.5,6,9 Reye’s syndrome occurs usually after a viral infection such as chic ...
- Madhya Pradesh Bhoj Open University
... program. Contributing factors include not only the compounds it was necessary to prepare before the most satisfactory was found, the medicinal chemists can contribute to the efficiency of developing or exploiting a lead by making fewest unsatisfactory compounds. The discovery of useful new drug or l ...
... program. Contributing factors include not only the compounds it was necessary to prepare before the most satisfactory was found, the medicinal chemists can contribute to the efficiency of developing or exploiting a lead by making fewest unsatisfactory compounds. The discovery of useful new drug or l ...
Infant Feeding Guidelines for Drug Using Mothers
... previous children) will expect to fail at breastfeeding and may give up after a day or two, even with support. A surprisingly low tolerance for discomfort also discourages many drug dependent women from breastfeeding when they develop sore nipples or uterine cramping. Breastfeeding among survivors o ...
... previous children) will expect to fail at breastfeeding and may give up after a day or two, even with support. A surprisingly low tolerance for discomfort also discourages many drug dependent women from breastfeeding when they develop sore nipples or uterine cramping. Breastfeeding among survivors o ...
Application of Quantitative Models of Choice to Alcohol
... by a maladaptive pattern of persistent drug seeking and taking (American Psychiatric Association [APA], 1994). Drug self-administration procedures have been useful in the study of the variables that contribute to the maintenance of drug taking and for the study of the reinforcing effects of drugs in ...
... by a maladaptive pattern of persistent drug seeking and taking (American Psychiatric Association [APA], 1994). Drug self-administration procedures have been useful in the study of the variables that contribute to the maintenance of drug taking and for the study of the reinforcing effects of drugs in ...
International Journal for Pharmaceutical Research Scholars (IJPRS)
... drug action is achieved by affecting the rate at which the drug is released from the dosage form and/or by slowing the transit time of the dosage form through the gastrointestinal tract. The rate of drug release from solid dosage forms may be modified by the technologies described next, which in gen ...
... drug action is achieved by affecting the rate at which the drug is released from the dosage form and/or by slowing the transit time of the dosage form through the gastrointestinal tract. The rate of drug release from solid dosage forms may be modified by the technologies described next, which in gen ...
The H2 Blockers` Rx-to OTC Switch: For Whom Will It Spell Relief
... any new applications to create a generic version of their drug for three years.22 The DPC-PTR Act also provides pharmaceutical companies with a patent extension option, under which the company can receive up to, provided that certain conditions are met, as many as five extra years on the term of one ...
... any new applications to create a generic version of their drug for three years.22 The DPC-PTR Act also provides pharmaceutical companies with a patent extension option, under which the company can receive up to, provided that certain conditions are met, as many as five extra years on the term of one ...
Therapeutic Drug Monitoring in the Geriatric Patient
... The complex process of aging is characterized by progressive loss in the functional capacities of organs, a reduction in mechanisms of homeostasis, and altered response to receptor stimulation.1 These changes combine to increase the susceptibility of elderly individuals to environmental and physical ...
... The complex process of aging is characterized by progressive loss in the functional capacities of organs, a reduction in mechanisms of homeostasis, and altered response to receptor stimulation.1 These changes combine to increase the susceptibility of elderly individuals to environmental and physical ...
Effects of cannabidiol on schizophrenia
... Moreover, this suggests that smoking strains of cannabis containing CBD in addition to D9-THC may be protective against the psychotic-like symptoms induced by D9-THC alone. This is further evident from the findings that participants with both D9-THC and CBD in their hair had significantly less anhed ...
... Moreover, this suggests that smoking strains of cannabis containing CBD in addition to D9-THC may be protective against the psychotic-like symptoms induced by D9-THC alone. This is further evident from the findings that participants with both D9-THC and CBD in their hair had significantly less anhed ...
Sample Chapter
... The complex process of aging is characterized by progressive loss in the functional capacities of organs, a reduction in mechanisms of homeostasis, and altered response to receptor stimulation.1 These changes combine to increase the susceptibility of elderly individuals to environmental and physical ...
... The complex process of aging is characterized by progressive loss in the functional capacities of organs, a reduction in mechanisms of homeostasis, and altered response to receptor stimulation.1 These changes combine to increase the susceptibility of elderly individuals to environmental and physical ...
Tuberculosis - An increasing global health problem
... HIV positive population has not been described in any national data, studies describe a percentage of approximately 33% in each category (pulmonary, non-pulmonary, both). [7] A person with active but untreated TB can infect 10–15 other people per year. [8] ...
... HIV positive population has not been described in any national data, studies describe a percentage of approximately 33% in each category (pulmonary, non-pulmonary, both). [7] A person with active but untreated TB can infect 10–15 other people per year. [8] ...
13. Major R&D Pipeline In-House R&D Pipeline List New Approval
... Description: Increases levels of the neurotransmitter acetylcholine in the brain by inhibiting its breakdown by the enzyme acetylcholinesterase, thereby slowing the overall progression of symptoms associated with Alzheimer’s disease (AD). Currently approved in more than 90 countries around the world ...
... Description: Increases levels of the neurotransmitter acetylcholine in the brain by inhibiting its breakdown by the enzyme acetylcholinesterase, thereby slowing the overall progression of symptoms associated with Alzheimer’s disease (AD). Currently approved in more than 90 countries around the world ...
Opioid and Cannabinoid Modulation of Precipitated Withdrawal in
... Received January 30, 2001; accepted May 11, 2001 ...
... Received January 30, 2001; accepted May 11, 2001 ...
Adverse Health Effects of Marijuana Use
... mate of use, since young people who have dropped out of school may have particularly high rates of frequent marijuana use.27 Since marijuana use impairs critical cognitive functions, both during acute intoxication and for days after use,28 many students could be functioning at a cognitive level that ...
... mate of use, since young people who have dropped out of school may have particularly high rates of frequent marijuana use.27 Since marijuana use impairs critical cognitive functions, both during acute intoxication and for days after use,28 many students could be functioning at a cognitive level that ...
IMPROVING THE PREDICTION OF PHARMACOGENES USING
... features, structural similarity and indication set similarity. The more similar the drugs in the local network of the gene are to the query drug, the higher the score the gene will receive. The original PGxPipeline9 used PharmGKB as a source of “genetic” drug-gene relationships, DrugBank as a source ...
... features, structural similarity and indication set similarity. The more similar the drugs in the local network of the gene are to the query drug, the higher the score the gene will receive. The original PGxPipeline9 used PharmGKB as a source of “genetic” drug-gene relationships, DrugBank as a source ...
Phase 1 study to evaluate the feasibility and efficacy
... imatinib 400mg or 600mg daily. The addition of pegylated interferon resulted in significantly higher rates of major molecular responses and complete molecular responses at 12 months [9]. Adverse events were higher in the combination treatment arms as well as in the imatinib 600mg arm compared to the ...
... imatinib 400mg or 600mg daily. The addition of pegylated interferon resulted in significantly higher rates of major molecular responses and complete molecular responses at 12 months [9]. Adverse events were higher in the combination treatment arms as well as in the imatinib 600mg arm compared to the ...
Ef fects of bupropion and me ca mylamine on mo ti va tional ef fects
... High rate of relapse to drug addiction is especially characteristic for people trying to quit tobacco. Moreover, smoking alcoholics are generally less successful at smoking cessation than are subjects without alcoholism [1]. Several laboratories have developed a reinstatement procedure based on the ...
... High rate of relapse to drug addiction is especially characteristic for people trying to quit tobacco. Moreover, smoking alcoholics are generally less successful at smoking cessation than are subjects without alcoholism [1]. Several laboratories have developed a reinstatement procedure based on the ...
AMERICAN ACADEMY OF PEDIATRICS Neonatal Drug Withdrawal
... Many studies that assess behavior and neurologic signs in cocaine-exposed infants have used scoring systems designed to assess opiate withdrawal. Some of the signs of opiate abstinence are commonly scored (Tables 3 and 4), but these signs are toxic effects of cocaine rather than evidence of withdraw ...
... Many studies that assess behavior and neurologic signs in cocaine-exposed infants have used scoring systems designed to assess opiate withdrawal. Some of the signs of opiate abstinence are commonly scored (Tables 3 and 4), but these signs are toxic effects of cocaine rather than evidence of withdraw ...
Adverse Health Effects of Marijuana Use
... mate of use, since young people who have dropped out of school may have particularly high rates of frequent marijuana use.27 Since marijuana use impairs critical cognitive functions, both during acute intoxication and for days after use,28 many students could be functioning at a cognitive level that ...
... mate of use, since young people who have dropped out of school may have particularly high rates of frequent marijuana use.27 Since marijuana use impairs critical cognitive functions, both during acute intoxication and for days after use,28 many students could be functioning at a cognitive level that ...
Cannabis use and misuse
... high calorie products. At low to moderate doses, cannabis typically has antiemetic effects (reduces nausea), but can induce nausea or vomiting at higher doses or among less experienced users. Cannabis use has a broad range of effects on cardiovascular function. Use is associated with increase in res ...
... high calorie products. At low to moderate doses, cannabis typically has antiemetic effects (reduces nausea), but can induce nausea or vomiting at higher doses or among less experienced users. Cannabis use has a broad range of effects on cardiovascular function. Use is associated with increase in res ...
Australian and New Zealand clinical practice guidelines
... term, although direct costs to patients vary). Of greatest benefit is the therapeutic relationship, which enables agreement on treatment selection and continuation. Regular monitoring for side-effects and encouragement to persist (or change treatment) are helpful. Table 2 compares antidepressants wi ...
... term, although direct costs to patients vary). Of greatest benefit is the therapeutic relationship, which enables agreement on treatment selection and continuation. Regular monitoring for side-effects and encouragement to persist (or change treatment) are helpful. Table 2 compares antidepressants wi ...
Dosage Form Design: Pharmaceutical and Formulation
... Liquid drugs pose an interesting problem in the design of dosage forms and delivery systems. Many liquids are volatile and must be physically sealed from the atmosphere to prevent evaporation loss. Amyl nitrite, for example, is a clear yellowish liquid that is volatile even at low temperatures and i ...
... Liquid drugs pose an interesting problem in the design of dosage forms and delivery systems. Many liquids are volatile and must be physically sealed from the atmosphere to prevent evaporation loss. Amyl nitrite, for example, is a clear yellowish liquid that is volatile even at low temperatures and i ...
Sublingual drug delivery system List of contents
... referred to as a dissolving film or strip. thin film strips are typically designed for oral administration, with the user placing the strip on or under the tongue or along the inside of the cheek. As the strip dissolves, the drug can enter the blood ...
... referred to as a dissolving film or strip. thin film strips are typically designed for oral administration, with the user placing the strip on or under the tongue or along the inside of the cheek. As the strip dissolves, the drug can enter the blood ...
I Adverse Health Effects of Marijuana Use review article
... mate of use, since young people who have dropped out of school may have particularly high rates of frequent marijuana use.27 Since marijuana use impairs critical cognitive functions, both during acute intoxication and for days after use,28 many students could be functioning at a cognitive level that ...
... mate of use, since young people who have dropped out of school may have particularly high rates of frequent marijuana use.27 Since marijuana use impairs critical cognitive functions, both during acute intoxication and for days after use,28 many students could be functioning at a cognitive level that ...
et al. TRANSDERMAL DRUG DELIVERY SYSTEM (TDDS): AN OVERVIEW
... often uses permeation enhancer(s) that increase the rate of transfer of drug(s) across the skin. In addition, adequate adhesiveness seems to be essential to ensure intimate contact of the formulation with skin for intended duration. Furthermore, choice of the rate controlling membrane is critical as ...
... often uses permeation enhancer(s) that increase the rate of transfer of drug(s) across the skin. In addition, adequate adhesiveness seems to be essential to ensure intimate contact of the formulation with skin for intended duration. Furthermore, choice of the rate controlling membrane is critical as ...
Polysubstance dependence
A person with polysubstance dependence is psychologically addicted to being in an intoxicated state without a preference for one particular substance. Although any combination of three drugs can be used, studies have shown that alcohol is commonly used with another substance. This is supported by one study on polysubstance use that separated participants who used multiple substances into groups based on their preferred drug. The three substances were cocaine, alcohol, and heroin, which implies that those three are very popular. Other studies have found that opiates, cannabis, amphetamines, hallucinogens, inhalants and benzodiazepines are often used in combination as well. The results of a long-term or longitudinal study on substance use led the researchers to observe that excessively using or relying on one drug increased the probability of excessively using or relying on another drug.