Artemisia annua (Asteraceae) Description of the plant Plant parts
... death markedly. The combination of artemisinin with other drugs like IFN-alpha or Ribavirin produced an additive protective effect. Artemisinin induced no toxicity in host cells. According to the authors artemisinin is useful in combination with current pharmacological therapy for the treatment of h ...
... death markedly. The combination of artemisinin with other drugs like IFN-alpha or Ribavirin produced an additive protective effect. Artemisinin induced no toxicity in host cells. According to the authors artemisinin is useful in combination with current pharmacological therapy for the treatment of h ...
Clinical application of extended-release hydromorphone for pain
... a central agent for the treatment of severe cancerrelated pain [2] . For both benign and oncologic pain, stable plasma levels of opioid are achieved through use of long-acting sustained-release opioid preparations [3] . While extended-release formulations of oxycodone, morphine, oxymorphone and fent ...
... a central agent for the treatment of severe cancerrelated pain [2] . For both benign and oncologic pain, stable plasma levels of opioid are achieved through use of long-acting sustained-release opioid preparations [3] . While extended-release formulations of oxycodone, morphine, oxymorphone and fent ...
Medical Review Officer Manual for Federal Agency Workplace Drug
... Before implementing an electronic Federal CCF, HHS-certified IITFs and laboratories must provide a detailed plan and proposed standard operating procedures (SOPs) which include the above items for SAMHSA review and approval (i.e., through SAMHSA’s National Laboratory Certification Program, NLCP), an ...
... Before implementing an electronic Federal CCF, HHS-certified IITFs and laboratories must provide a detailed plan and proposed standard operating procedures (SOPs) which include the above items for SAMHSA review and approval (i.e., through SAMHSA’s National Laboratory Certification Program, NLCP), an ...
Dose uniformity of topical corticosteroid preparations: difluprednate
... with little variability. Only one datum point was not within 10% of declared concentration, and this was likely an outlier, as evidenced by the fact that the other 40 data points from this testing condition were within 4.2% of declared concentration. These results were reproduced in multiple additio ...
... with little variability. Only one datum point was not within 10% of declared concentration, and this was likely an outlier, as evidenced by the fact that the other 40 data points from this testing condition were within 4.2% of declared concentration. These results were reproduced in multiple additio ...
data sheet
... nervous system effects of methadone. Use in the Elderly: Methadone has a long plasma half life which may lead to accumulation, particularly if renal function is impaired (see Renal Impairment). In common with other opioids, methadone may cause confusion in this age group, therefore careful monitorin ...
... nervous system effects of methadone. Use in the Elderly: Methadone has a long plasma half life which may lead to accumulation, particularly if renal function is impaired (see Renal Impairment). In common with other opioids, methadone may cause confusion in this age group, therefore careful monitorin ...
butorphanol tartrate injection usp
... insufficiency should be limited to those situations where the benefits clearly outweigh the risk (see CLINICAL PHARMACOLGY). Severe hypertension has been reported rarely during butorphanol therapy. In such cases, butorphanol should be discontinued and the hypertension treated with antihypertensive d ...
... insufficiency should be limited to those situations where the benefits clearly outweigh the risk (see CLINICAL PHARMACOLGY). Severe hypertension has been reported rarely during butorphanol therapy. In such cases, butorphanol should be discontinued and the hypertension treated with antihypertensive d ...
(PSD) July 2016 PBAC Meeting - (Word 86KB)
... endpoint of progression of disability. Daclizumab presents more risk of serious adverse effects than IFN β-1a. Given these factors it is not clear whether use of this product should be permitted at all or whether restricting its use to patients who have failed initial treatment would be appropriate. ...
... endpoint of progression of disability. Daclizumab presents more risk of serious adverse effects than IFN β-1a. Given these factors it is not clear whether use of this product should be permitted at all or whether restricting its use to patients who have failed initial treatment would be appropriate. ...
united states district court
... since 1982. I have been Board Certified in Family Medicine and a Diplomate of the American Board of Family Practice since 1982. I graduated cum laude from Harvard College in 1970 with a degree in Social Relations. I attended Dartmouth Medical School and graduated with a degree in Medicine from Brown ...
... since 1982. I have been Board Certified in Family Medicine and a Diplomate of the American Board of Family Practice since 1982. I graduated cum laude from Harvard College in 1970 with a degree in Social Relations. I attended Dartmouth Medical School and graduated with a degree in Medicine from Brown ...
HYDROCODONE BITARTRATE AND ACETAMINOPHEN
... patients with a personal or family history of substance abuse (including drug or alcohol abuse or addiction) or mental illness (e.g., major depression). The potential for these risks should not, however, prevent the proper management of pain in any given patient. Patients at increased risk may be pr ...
... patients with a personal or family history of substance abuse (including drug or alcohol abuse or addiction) or mental illness (e.g., major depression). The potential for these risks should not, however, prevent the proper management of pain in any given patient. Patients at increased risk may be pr ...
Abstract Ethnopharmacological relevance Achillea millefolium L
... disturbances (Andreatini et al., 2001, Carlini, 2003 and Mitte et al., 2005). Medicinal plants continue to have anxiolytic potential (Carlini, 2003 and Faustino et al., 2010). The elevated plus maze is likely the most frequently used animal model for studying anxiety and anxiolytic-like drugs (Caro ...
... disturbances (Andreatini et al., 2001, Carlini, 2003 and Mitte et al., 2005). Medicinal plants continue to have anxiolytic potential (Carlini, 2003 and Faustino et al., 2010). The elevated plus maze is likely the most frequently used animal model for studying anxiety and anxiolytic-like drugs (Caro ...
this paper
... volume of 10 ml / kg. All drug doses were calculated as milligrams per kilogram base weight and were dissolved in 0.9% saline. Forced swimming test. To facilitate adaptation to novel surroundings, mice were transported to the testing room at least 1 hr before testing. All experimental testing sessio ...
... volume of 10 ml / kg. All drug doses were calculated as milligrams per kilogram base weight and were dissolved in 0.9% saline. Forced swimming test. To facilitate adaptation to novel surroundings, mice were transported to the testing room at least 1 hr before testing. All experimental testing sessio ...
Evaluation of Pharmacokinetic Interaction between PA
... CYP3A4 and/or p-glycoprotein and have interactions with drugs for the treatment of TB, such as rifampin, that are inducers of hepatic enzymes (9). In vitro data indicate that PA-824 is not an inducer but is a weak substrate and potential weak inhibitor of CYP3A4 (data not shown). An assessment of PA ...
... CYP3A4 and/or p-glycoprotein and have interactions with drugs for the treatment of TB, such as rifampin, that are inducers of hepatic enzymes (9). In vitro data indicate that PA-824 is not an inducer but is a weak substrate and potential weak inhibitor of CYP3A4 (data not shown). An assessment of PA ...
Poonam et al - Galaxy of Pharmaceutical Innovations
... pharmaceutical sciences, but no such inhibitors has been available.One difficulty in discovering of universal inhibitor for bitter taste is that substances that inhibits bitterness of one compound will not influence the bitterness of a second because many different classes of compound impart bittern ...
... pharmaceutical sciences, but no such inhibitors has been available.One difficulty in discovering of universal inhibitor for bitter taste is that substances that inhibits bitterness of one compound will not influence the bitterness of a second because many different classes of compound impart bittern ...
Modafinil attenuates reinstatement of cocaine seeking: role for
... Modafinil may be useful for treating stimulant abuse, but the mechanisms by which it acts to do so are unknown. Indeed, a primary effect of modafinil is to inhibit dopamine transport, which typically promotes rather than inhibits motivated behavior. Therefore, we examined the role of nucleus accumbe ...
... Modafinil may be useful for treating stimulant abuse, but the mechanisms by which it acts to do so are unknown. Indeed, a primary effect of modafinil is to inhibit dopamine transport, which typically promotes rather than inhibits motivated behavior. Therefore, we examined the role of nucleus accumbe ...
PRODUCT INFORMATION METHADONE SYRUP
... In vivo and in vitro studies have demonstrated that methadone inhibits cardiac potassium channels and prolongs cardiac repolarisation (i.e. prolongs the QT interval). QT interval prolongation and serious arrhythmia (Torsade de Pointes) have been observed during treatment with methadone and appear to ...
... In vivo and in vitro studies have demonstrated that methadone inhibits cardiac potassium channels and prolongs cardiac repolarisation (i.e. prolongs the QT interval). QT interval prolongation and serious arrhythmia (Torsade de Pointes) have been observed during treatment with methadone and appear to ...
Comparison of HFNC, Bubble CPAP, and SiPAP on Aerosol
... Background: Aerosol drug delivery via high flow nasal cannula (HFNC), bubble continuous positive airway pressure (CPAP), and synchronized inspiratory positive airway pressure (SiPAP) has not been quantified in spontaneously breathing premature infants. The purpose of this study was to compare HFNC, ...
... Background: Aerosol drug delivery via high flow nasal cannula (HFNC), bubble continuous positive airway pressure (CPAP), and synchronized inspiratory positive airway pressure (SiPAP) has not been quantified in spontaneously breathing premature infants. The purpose of this study was to compare HFNC, ...
Caffeine Content of Decaffeinated Coffee
... doses of caffeine or placebo for a 300 rag/day maintenance dose. It was found that substituting lower doses of caffeine or placebo resulted in an increase in withdrawal symptoms, such as drowsiness, headache, impaired concentration and decreased sociability. When caffeine doses in the range of 25-10 ...
... doses of caffeine or placebo for a 300 rag/day maintenance dose. It was found that substituting lower doses of caffeine or placebo resulted in an increase in withdrawal symptoms, such as drowsiness, headache, impaired concentration and decreased sociability. When caffeine doses in the range of 25-10 ...
modafinil - Awake Institute, LLC
... who took 400 mg of modafinil or placebo found significant improvements in alertness (MWT), but no effects on sleepiness (MSLT) or ESS, and no effects on cognitive function or quality of life. While these modest results may reflect the small sample size or the limitations of the measures, the investi ...
... who took 400 mg of modafinil or placebo found significant improvements in alertness (MWT), but no effects on sleepiness (MSLT) or ESS, and no effects on cognitive function or quality of life. While these modest results may reflect the small sample size or the limitations of the measures, the investi ...
Pharmacokinetic Drug Interactions of Antimicrobial Drugs: A
... extent of severity and clinical relevance. Not only co-medication, but also food and herbal medicine can interact with antimicrobial drugs and vice versa. The nature of these interactions can be of pharmacodynamic (PD) and/or pharmacokinetic (PK) origin. A PD interaction consists of an alteration of ...
... extent of severity and clinical relevance. Not only co-medication, but also food and herbal medicine can interact with antimicrobial drugs and vice versa. The nature of these interactions can be of pharmacodynamic (PD) and/or pharmacokinetic (PK) origin. A PD interaction consists of an alteration of ...
depo-provera - Pfizer Canada
... events in obese DEPO-PROVERA women. Women with a prior history of thromboembolic disorders have not been studied in clinical trials and no information is available that would support the safety of DEPO-PROVERA use in this population. Before prescribing DEPO-PROVERA, the physician should be alert to ...
... events in obese DEPO-PROVERA women. Women with a prior history of thromboembolic disorders have not been studied in clinical trials and no information is available that would support the safety of DEPO-PROVERA use in this population. Before prescribing DEPO-PROVERA, the physician should be alert to ...
The PBAC agenda primarily consists of applications relating
... Consumers will have the opportunity to provide comments on new drug submissions (item 5), changes to listings (item 6) and resubmissions (item 7). In many circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be list ...
... Consumers will have the opportunity to provide comments on new drug submissions (item 5), changes to listings (item 6) and resubmissions (item 7). In many circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be list ...
Chapter 018
... About two-thirds of American adults consume alcohol; about 14% of them develop problems with dependence Roughly one-third of all hospital admissions are related to alcohol abuse The divorce rate for couples with and alcoholic spouse is seven times greater than that for other couples ...
... About two-thirds of American adults consume alcohol; about 14% of them develop problems with dependence Roughly one-third of all hospital admissions are related to alcohol abuse The divorce rate for couples with and alcoholic spouse is seven times greater than that for other couples ...
March 2016 PBAC Meeting Agenda
... Consumers will have the opportunity to provide comments on new drug submissions (item 5), changes to listings (item 6) and resubmissions (item 7). In many circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be list ...
... Consumers will have the opportunity to provide comments on new drug submissions (item 5), changes to listings (item 6) and resubmissions (item 7). In many circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be list ...
![Cucurbit[n]urils as excipients in pharmaceutical dosage forms](http://s1.studyres.com/store/data/005393778_1-462b4ddd8a98f7dba6c184d59041de9f-300x300.png)
Cucurbit[n]urils as excipients in pharmaceutical dosage forms
... method, cucurbit[n]uril powders can contain large quantities of water and they are also known to be hygroscopic. For instance, the method of Day et al to produce CB[8] yields a hydrated form of the macrocycle with 30 waters of crystallisation (29). While different methods of cucurbit[n]uril producti ...
... method, cucurbit[n]uril powders can contain large quantities of water and they are also known to be hygroscopic. For instance, the method of Day et al to produce CB[8] yields a hydrated form of the macrocycle with 30 waters of crystallisation (29). While different methods of cucurbit[n]uril producti ...
Polysubstance dependence
A person with polysubstance dependence is psychologically addicted to being in an intoxicated state without a preference for one particular substance. Although any combination of three drugs can be used, studies have shown that alcohol is commonly used with another substance. This is supported by one study on polysubstance use that separated participants who used multiple substances into groups based on their preferred drug. The three substances were cocaine, alcohol, and heroin, which implies that those three are very popular. Other studies have found that opiates, cannabis, amphetamines, hallucinogens, inhalants and benzodiazepines are often used in combination as well. The results of a long-term or longitudinal study on substance use led the researchers to observe that excessively using or relying on one drug increased the probability of excessively using or relying on another drug.