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A Brief History of Heroin Use in the United States
A Brief History of Heroin Use in the United States

... However, more significant possibly than the tax itself were two seemingly innocuous components of the law. First, the law defined narcotics as both opium- and coca-based drugs, thus combining drugs like heroin and cocaine into a single category. This was completely contrary to medical practice which ...
CLINICAL TRIALS (2).
CLINICAL TRIALS (2).

... while they are observed and tested for a period of time. • If they do not exhibit any adverse side effects, and the pharmacokinetic data is roughly in line with predicted safe values, the dose is escalated, and a new group of subjects is then given a higher dose. • This is continued until pre-calcul ...
Improving Access to Essential Medicines
Improving Access to Essential Medicines

... It has been shown that it is possible to establish a viable RDF programme at the district level provided there is a strong M & component in the activities The Ministry of Health has proposed the expansion of the project into 15 districts forming satellites around Nyamira district. This will present ...
Moving Evidence Based Treatment into the Drug Court Setting
Moving Evidence Based Treatment into the Drug Court Setting

... Effective trial courts are responsive to emergent public issues such as drug abuse, child and spousal abuse, AIDS, drunken driving, child support enforcement, crime and public safety, consumer rights, gender bias, and the more efficient use of fewer resources. ...
Drug Interactions - Dumfries and Galloway Prescribing Support Team
Drug Interactions - Dumfries and Galloway Prescribing Support Team

... the enhanced hypotensive effect of giving an ACE inhibitor and doxazosin. Where the effects of the drugs are antagonistic we may see a reduction in the effect of one or both drugs when they are co-administered e.g. β-agonists and β-antagonists will compete for receptor sites. Pharmacokinetic interac ...
Chapter Seven: Recognizing and Avoiding Addiction and Drug Abuse
Chapter Seven: Recognizing and Avoiding Addiction and Drug Abuse

... and 124% in children over the past decade, (Prozac, Zoloft, Paxil) ...
A C D M I S S I O N
A C D M I S S I O N

... Client must meet at least three of the following criteria for a diagnosis of substance dependence. • Evidence of tolerance to an opioid drug • Evidence of withdrawal from a opioid drug • Substance is taken in larger amounts or over a longer time than controlling use • Increased time spent in activit ...
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New Irish study shows high alcohol consumption in older population
New Irish study shows high alcohol consumption in older population

... New Irish study shows high alcohol consumption in older population on prescribed medication Researcher warns of future increase in risk of alcohol related adverse drug events ...
Professional Competency #4: Manage Drug Distribution
Professional Competency #4: Manage Drug Distribution

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youth and drug abuse - World Assembly of Youth
youth and drug abuse - World Assembly of Youth

... Due to their socio-economic status, developing countries often tend to have more complex problems with the abuse of substances like alcohol, tobacco smoking, use of cannabis and the sniffing of glue and other volatile substances. With economic and social development, however, according to Scanlon, t ...
Wise Up Presentations
Wise Up Presentations

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Treatment Planning
Treatment Planning

... brief interventions: for non-dependent problem drink/drug user Comprehensive assessment and individualized treatment plan: each client experiences problems differently) Care management: All elements of the problem should be addressed and coordinated Individually delivered, proven professional interv ...
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Substance Abuse Treatment

... HIV positive clients may access any service offered by the HRR agency (both low threshold AOD and AOD services). Low threshold services are sometimes designed to engage new HIV positive clients in services (i.e., talking about risk reduction, decision making skills, etc.) or to support HIV positive ...
senate health
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... Product ($3 trillion, or $9,523 per person) and health care costs continue to consume significantly large percentages of federal, state and personal budgets. Health care continues to grow at higher rates than inflation. In 2013, the U.S. spent far more on health care than other high-income countries ...
Management of Anaphylaxis - University of Michigan Home Care
Management of Anaphylaxis - University of Michigan Home Care

... Anaphylaxis: An acute, potentially fatal, systemic reaction that can occur as a result of medication administration and which requires emergency management. PROCEDURES: A. ...
2015 Blue Medicare Rx Standard Plan
2015 Blue Medicare Rx Standard Plan

... b. Have the potential side effects and risks of the requested drug been discussed with the patient or authorized representative of the patient? □ YES □ NO Note: the following must be met for approval of any non-formulary drug:  Member must have tried and failed at least one alternative formulary dr ...
Illicit drugs and drug interactions
Illicit drugs and drug interactions

... perception, and extraversion. Adverse effects are similar to those of amphetamines related to excessive CNS and cardiovascular stimulation.12,18 Additional effects related to serotonergic excess include jaw clenching and tooth grinding. ...
Drug dosing in dialysis patients
Drug dosing in dialysis patients

... and lessen the likelihood of sub-therapeutic regimens or overdoses • In the absence of a loading dose, maintenance doses will achieve 90% of their steady-state level in 3–4½ lives • Two options for ESRD • Reduce the dose • Lengthen the interval between doses (more useful for a drug with a wide thera ...
What is Pharmacology?
What is Pharmacology?

... • Involves a carrier (a component of the membrane) which binds reversibly with the solute molecules to be transported to yield the carrier solute complex which transverses across the membrane to the other side where it dissociates to yield the solute molecule • The carrier then returns to its origin ...
Paediatric HIV Care - HIV i-Base
Paediatric HIV Care - HIV i-Base

... Unclear what would have happened if preferred ARVs were more expensive: lucky that preferred drugs tendered best prices ...
Drug Interactions - STA HealthCare Communications
Drug Interactions - STA HealthCare Communications

... enzyme.5 Metoprolol is processed by this enzyme. Therefore, deficient patients would not be able to process metoprolol and, hence, even a small dose would result in very high blood levels of metoprolol. Another example involves codeine. Codeine is a prodrug that requires CYP 2D6 to convert it into m ...
The Medical Evaluation in Diagnosing Tuberculosis 2008
The Medical Evaluation in Diagnosing Tuberculosis 2008

... Tuberculosis Evaluation in the Underserved Community ...
Development of Probiotics as Biologic Drugs
Development of Probiotics as Biologic Drugs

... of the body” [5]. If a drug is “not generally recognized as safe and effective under the conditions prescribed, recommended, or suggested in the labeling (and marketed after 1938),” it is a “new” drug [6]. Prior to US marketing, new drugs must demonstrate both safety and efficacy. Efficacy is define ...
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Harm reduction



Harm reduction (or harm minimization) is a range of public health policies designed to reduce the harmful consequences associated with various human behaviors, both legal and illegal. Harm reduction policies are used to manage behaviors such as recreational drug use and sexual activity in numerous settings that range from services through to geographical regions. Critics of harm reduction typically believe that tolerating risky or illegal behaviour sends a message to the community that such behaviours are acceptable and that some of the actions proposed by proponents of harm reduction do not reduce harm over the long term.Needle-exchange programmes reduce the likelihood of users of heroin and other drugs sharing the syringes and using them more than once. Syringe-sharing can lead to infections such as HIV or hepatitis C can spread from user to users through the reuse of syringes contaminated with infected blood. Needle and syringe programme (NSP) and Opioid Substitution Therapy (OST) outlets in some settings offer basic primary health care. Safe injection site are legally sanctioned, medically supervised facilities designed to address public nuisance associated with drug use and provide a hygienic and stress-free environment for drug consumers. The facilities provide sterile injection equipment, information about drugs and basic health care, treatment referrals, and access to medical staff.Opioid replacement therapy (ORT), or opioid substitution therapy (OST), is the medical procedure of replacing an illegal opioid, such as heroin, with a longer acting but less euphoric opioid; methadone or buprenorphine are typically used and the drug is taken under medical supervision. Another approach is Heroin assisted treatment, in which medical prescriptions for pharmaceutical heroin (diacetylmorphine) are provided to heroin-dependent people. Toronto's Seaton House became the first homeless shelter in Canada to operate a ""wet shelter"" on a ""managed alcohol"" principle in which clients are served a glass of wine once an hour unless staff determine that they are too inebriated to continue. Previously, homeless alcoholics opted to stay on the streets often seeking alcohol from unsafe sources such as mouthwash, rubbing alcohol or industrial products which, in turn, resulted in frequent use of emergency medical facilities.A high amount of media coverage exists informing users of the dangers of driving drunk. Most alcohol users are now aware of these dangers and safe ride techniques like 'designated drivers' and free taxicab programmes are reducing the number of drunk-driving accidents. Many schools now provide safer sex education to teen and pre-teen students, who may engage in sexual activity. Since some adolescents are going to have sex, a harm-reductionist approach supports a sexual education which emphasizes the use of protective devices like condoms and dental dams to protect against unwanted pregnancy and the transmission of STIs. Since 1999 some countries have legalized prostitution, such as Germany (2002) and New Zealand (2003).Many street-level harm-reduction strategies have succeeded in reducing HIV transmission in injecting drug users and sex-workers. HIV education, HIV testing, condom use, and safer-sex negotiation greatly decreases the risk to the disease.
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