... With few exceptions, efficacy of the agent in question in clinical trials was almost uniformly “equal” to that of comparators. The question as to whether one βlactam performs better than another remains largely unanswered. Most antibiotic trials (typically with <500 subjects in each arm) simply lack ...
rav
... Drugs for CCF Cardiac glycosides : Digoxin : Increase the refractoriness of AV node thus decrease ventricular response to atrial rate. Digoxin is used as a first-line drug in patients with congestive heart failure who are in atrial fibrillation. ...
... Drugs for CCF Cardiac glycosides : Digoxin : Increase the refractoriness of AV node thus decrease ventricular response to atrial rate. Digoxin is used as a first-line drug in patients with congestive heart failure who are in atrial fibrillation. ...
Document
... – Atropine suppresses thermoregulatory sweating. – In adults, body temperature is elevated by this effect only if large doses are administered, but in infants and children even ordinary doses may cause "atropine fever." ...
... – Atropine suppresses thermoregulatory sweating. – In adults, body temperature is elevated by this effect only if large doses are administered, but in infants and children even ordinary doses may cause "atropine fever." ...
Clinical Evaluation of Topical Application of Doxycycline 3% +
... Numerous host modulatory agents have been investigated in clinical trials. Non-steroidal anti-inflammatory drugs (NSAIDs), antimicrobial of doxycycline and or a combination of drugs have been successfully applied as an adjunct to non-surgical mechanical periodontal treatment [19,20]. Even so, the ex ...
... Numerous host modulatory agents have been investigated in clinical trials. Non-steroidal anti-inflammatory drugs (NSAIDs), antimicrobial of doxycycline and or a combination of drugs have been successfully applied as an adjunct to non-surgical mechanical periodontal treatment [19,20]. Even so, the ex ...
substance abuse - Nurses Learning Network
... nature of drugs and their effects upon the human body. One person may take a drug at some time in their life (prescribed or not) and never have any craving for that drug again. However, another person may take that same drug and then develop a life-long addiction to that same drug. It is still uncle ...
... nature of drugs and their effects upon the human body. One person may take a drug at some time in their life (prescribed or not) and never have any craving for that drug again. However, another person may take that same drug and then develop a life-long addiction to that same drug. It is still uncle ...
DRUG NAME: Sorafenib
... Sorafenib inhibits glucuronidation by the UGT1A1 and UGT1A9 pathways. Systemic exposure to substrates of UGT1A1 and UGT1A9 may be increased when co-administered with sorafenib. Caution is recommended when administering sorafenib together with compounds that are metabolized/eliminated predominantly b ...
... Sorafenib inhibits glucuronidation by the UGT1A1 and UGT1A9 pathways. Systemic exposure to substrates of UGT1A1 and UGT1A9 may be increased when co-administered with sorafenib. Caution is recommended when administering sorafenib together with compounds that are metabolized/eliminated predominantly b ...
5 Calcium Antagonists (Calcium Channel Blockers)
... congestion and LV dysfunction, EF < 40%. The increase in mortality persisted through long-term therapy beyond 1 yr (20). Congestive HF occurred in 39 (12%) patients receiving placebo and in 61 (21%) patients given diltiazem. Diltiazem is currently not approved by the U.S. Food and Drug Administratio ...
... congestion and LV dysfunction, EF < 40%. The increase in mortality persisted through long-term therapy beyond 1 yr (20). Congestive HF occurred in 39 (12%) patients receiving placebo and in 61 (21%) patients given diltiazem. Diltiazem is currently not approved by the U.S. Food and Drug Administratio ...
1 PRODUCT INFORMATION FLIXOTIDE NEBULES NAME OF THE
... doses of fluticasone propionate up to 57 µg/kg/day by inhalation or in an 18 month study in mice receiving oral doses of fluticasone propionate up to 1 mg/kg/day. There was no evidence of a mutagenic potential in a standard battery of mutagenicity assays. A fertility study in rats showed decreased m ...
... doses of fluticasone propionate up to 57 µg/kg/day by inhalation or in an 18 month study in mice receiving oral doses of fluticasone propionate up to 1 mg/kg/day. There was no evidence of a mutagenic potential in a standard battery of mutagenicity assays. A fertility study in rats showed decreased m ...
Leyden: N Engl J Med, Volume 336(16).Apr 17, 1997.pp 1156
... The earliest clinical expression of acne is usually noninflammatory comedones, which are typically found on the central forehead, chin, nose, and paranasal areas. This form of acne develops in the pre-teenage or early teenage years and is a consequence of increased sebum production and abnormal desq ...
... The earliest clinical expression of acne is usually noninflammatory comedones, which are typically found on the central forehead, chin, nose, and paranasal areas. This form of acne develops in the pre-teenage or early teenage years and is a consequence of increased sebum production and abnormal desq ...
Recent developments on the detection of harms arising from the use
... been detected in 28 MS, Turkey and Norway. In excess of 5200 seizures were reported with 8 countries reporting > 100 seizures each (UK, FI, SK, SE, IE, HU & TK). The total amount of powder seized was over 750 kg. • It has been seized as a powder, but other forms including tablets have been detected. ...
... been detected in 28 MS, Turkey and Norway. In excess of 5200 seizures were reported with 8 countries reporting > 100 seizures each (UK, FI, SK, SE, IE, HU & TK). The total amount of powder seized was over 750 kg. • It has been seized as a powder, but other forms including tablets have been detected. ...
Allergic Rhinitis
... o For greatest efficacy, must cover entire nasal lining o Blow nose before administering o Dosing really should be spaced q6h to maintain effect Efficacy: o less effective than nasal steroids or second generation antihistamines o most effective for allergic rhinitis when initiated just prior to th ...
... o For greatest efficacy, must cover entire nasal lining o Blow nose before administering o Dosing really should be spaced q6h to maintain effect Efficacy: o less effective than nasal steroids or second generation antihistamines o most effective for allergic rhinitis when initiated just prior to th ...
Anticholinergics for Overactive Bladder Therapy: Central Nervous
... The adverse events most commonly associated with the use of antimuscarinic OAB drugs are the expected side effects of anticholinergics, such as dry mouth and constipation. CNS adverse events were generally observed in fewer than 10% of patients in phase III clinical trials, and were highest in patie ...
... The adverse events most commonly associated with the use of antimuscarinic OAB drugs are the expected side effects of anticholinergics, such as dry mouth and constipation. CNS adverse events were generally observed in fewer than 10% of patients in phase III clinical trials, and were highest in patie ...
RETROVIRAL DISEASE
... (HAART) medications and other therapies related to HIV patients. 2. To assist patient to recognise and manage adverse drug effects due to their HAART medications and other therapy. 3. To become the source of information for patient/caregivers. 4. To collaborate with physicians and other healthcar ...
... (HAART) medications and other therapies related to HIV patients. 2. To assist patient to recognise and manage adverse drug effects due to their HAART medications and other therapy. 3. To become the source of information for patient/caregivers. 4. To collaborate with physicians and other healthcar ...
TRIESENCE® Suspension (triamcinolone acetonide injectable
... When the use of TRIESENCE® Suspension is reasonable and necessary and is administered incident to a physician’s service, Medicare will provide coverage and reimbursement for the drug. For 2012 the Medicare reimbursement rate for separately payable drugs and biologicals is Average Sell Price (ASP) + ...
... When the use of TRIESENCE® Suspension is reasonable and necessary and is administered incident to a physician’s service, Medicare will provide coverage and reimbursement for the drug. For 2012 the Medicare reimbursement rate for separately payable drugs and biologicals is Average Sell Price (ASP) + ...
here - Farmavita.Net
... transaminase measurements should be obtained prior to starting and monthly during preventative therapy, or more frequently as needed. If any of the values exceed three to five times the upper limit of normal isoniazid should be temporarily discontinued and consideration given to restarting therapy. ...
... transaminase measurements should be obtained prior to starting and monthly during preventative therapy, or more frequently as needed. If any of the values exceed three to five times the upper limit of normal isoniazid should be temporarily discontinued and consideration given to restarting therapy. ...
Tinea Capitis - Jason Carter MD
... Tinea capitis is one of the most common dermatophyte infections in the pediatric population, affecting up to 4% of all children. The peak age is 4 to 6 years; infection is rare after puberty. Systemic therapy is generally required.[6] The exact efficacy of any agent is difficult to determine, becaus ...
... Tinea capitis is one of the most common dermatophyte infections in the pediatric population, affecting up to 4% of all children. The peak age is 4 to 6 years; infection is rare after puberty. Systemic therapy is generally required.[6] The exact efficacy of any agent is difficult to determine, becaus ...
Liothyronine Basics
... Note: Several medications have effects on thyroid production or conversion. The impact in thyroid replacement has not been specifically evaluated, but patient response should be monitored: Methimazole: Decreases thyroid hormone secretion, while propylthiouracil decrease thyroid hormone secretion and ...
... Note: Several medications have effects on thyroid production or conversion. The impact in thyroid replacement has not been specifically evaluated, but patient response should be monitored: Methimazole: Decreases thyroid hormone secretion, while propylthiouracil decrease thyroid hormone secretion and ...
Preventative therapy - Amazon Web Services
... a candidate for daily therapy to prevent the attacks. The first agents to consider would be baby aspirin or propranolol. In evaluating the results of preventative therapy the following factors must be remembered. About one forth of adolescent males with episodic migraine note a spontaneous terminati ...
... a candidate for daily therapy to prevent the attacks. The first agents to consider would be baby aspirin or propranolol. In evaluating the results of preventative therapy the following factors must be remembered. About one forth of adolescent males with episodic migraine note a spontaneous terminati ...
Bossong et al 2005 proefprint AB-2
... Meta-chlorophenylpiperazine: mCPP In September 2004, another ecstasy-like drug appeared on the Dutch drug market: meta-chlorophenylpiperazine (mCPP). mCPP is a pharmacologically active metabolite of the antidepressant drugs trazodone, nefazodone and etoperidone and of the minor tranquillizer mepipra ...
... Meta-chlorophenylpiperazine: mCPP In September 2004, another ecstasy-like drug appeared on the Dutch drug market: meta-chlorophenylpiperazine (mCPP). mCPP is a pharmacologically active metabolite of the antidepressant drugs trazodone, nefazodone and etoperidone and of the minor tranquillizer mepipra ...
Metformin Associated B12 Deficiency
... because of a calcium dependent ileal membrane antagonism. Low B12 levels due to prolonged metformin use can cause or exacerbate diabetic peripheral neuropathy (DPN).5 Low serum B12 levels also alter cerebral functions like memory, cognition, alertness etc. DPN is a common disorder and estimates show ...
... because of a calcium dependent ileal membrane antagonism. Low B12 levels due to prolonged metformin use can cause or exacerbate diabetic peripheral neuropathy (DPN).5 Low serum B12 levels also alter cerebral functions like memory, cognition, alertness etc. DPN is a common disorder and estimates show ...
jwh-018 - Ministry of Health
... people who may not have the expertise, tools or intent to otherwise prepare these products for inhalation. 24. Finally, the aggressive marketing and free of charge giveaways of herbal smoking blends over social networking sites such as “Facebook” may further the appeal of these products to young peo ...
... people who may not have the expertise, tools or intent to otherwise prepare these products for inhalation. 24. Finally, the aggressive marketing and free of charge giveaways of herbal smoking blends over social networking sites such as “Facebook” may further the appeal of these products to young peo ...
sucralfate tablets, usp - Nostrum Laboratories Inc.
... be used during pregnancy only if clearly needed. Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when sucralfate is administered to a nursing woman. Pediatric Use Safety and effectiveness in pedia ...
... be used during pregnancy only if clearly needed. Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when sucralfate is administered to a nursing woman. Pediatric Use Safety and effectiveness in pedia ...
Headline - American College of Cardiology
... • In 3,845 patients ≥80 years old with SBP ≥160 mm Hg, at 1.8-year follow-up, those randomized to indapamide vs placebo had: – 30% nonsignificant decrease in fatal/nonfatal stroke – 39% significant decrease in fatal stroke – 21% significant decrease in all-cause mortality – 23% insignificant decreas ...
... • In 3,845 patients ≥80 years old with SBP ≥160 mm Hg, at 1.8-year follow-up, those randomized to indapamide vs placebo had: – 30% nonsignificant decrease in fatal/nonfatal stroke – 39% significant decrease in fatal stroke – 21% significant decrease in all-cause mortality – 23% insignificant decreas ...
PRODUCT MONOGRAPH ANAFRANIL - Sunovion Pharmaceuticals
... have been reported, the clinical significance of elevated serum prolactin levels is unknown for most patients. An increase in mammary neoplasms has been found in rodents after chronic administration of neuroleptic drugs. Neither clinical studies nor epidemiologic studies conducted to date, however, ...
... have been reported, the clinical significance of elevated serum prolactin levels is unknown for most patients. An increase in mammary neoplasms has been found in rodents after chronic administration of neuroleptic drugs. Neither clinical studies nor epidemiologic studies conducted to date, however, ...
Drug Therapy
... Patient teaching regarding sublingual nitroglycerin should include which of the following statements: A. "You can take up to five doses every 3 minutes for chest pain." B. "Chew the tablet for the quickest effect." C. "Keep the tablets locked in a safe place until you need them." D. * "Sit or lie do ...
... Patient teaching regarding sublingual nitroglycerin should include which of the following statements: A. "You can take up to five doses every 3 minutes for chest pain." B. "Chew the tablet for the quickest effect." C. "Keep the tablets locked in a safe place until you need them." D. * "Sit or lie do ...