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Basics Pharmacology Review - Dr. Roland Halil
Basics Pharmacology Review - Dr. Roland Halil

... (Partially adapted from slides by Marc Riachi, R.Ph.) ...
DATA SHEET DALACIN C PHOSPHATE
DATA SHEET DALACIN C PHOSPHATE

... The use of clindamycin can lead to the development of severe colitis. Fatalities have been reported. Therefore, DALACIN C Phosphate should be reserved for serious infections where less toxic antimicrobial agents are inappropriate, as described in the INDICATIONS section. It should not be used in pat ...
Impact of Urinary Incontinence
Impact of Urinary Incontinence

... + biofeedback compared to PFME only. However, no change in groups after 3 months. ...
European Heart Rhythm Association Practical Guide on the use of
European Heart Rhythm Association Practical Guide on the use of

... patients on NOACs; (2) How to measure the anticoagulant effect of NOACs; (3) Drug–drug interactions and pharmacokinetics of NOACs; (4) Switching between anticoagulant regimens; (5) Ensuring compliance of NOAC intake; (6) How to deal with dosing errors; (7) Patients with chronic kidney disease; (8) W ...
the concept of the therapeutic window in the choice of h1
the concept of the therapeutic window in the choice of h1

... Variations in the population and among different racial populations, in terms of the metabolism of antihistamines, may theoretically alter the position of a certain drug within its known therapeutic window. Little is known about how this variable influences either the efficacy or the side-effect pro ...
Synthetic cannabinoid case study – various brands | Male
Synthetic cannabinoid case study – various brands | Male

... collectors’ items and research chemicals. In the recent past, NPS were often sold under even more deceptive names, such as ‘plant food’ or ‘bathsalts’ but this is less common now and these products are not dual purpose. The term legal high might imply that these substances are safe but this is an in ...
Seretide Accuhaler
Seretide Accuhaler

... clearance mediated by cytochrome P450 3A4 in the gut and liver. Hence, clinically significant drug interactions mediated by fluticasone propionate are unlikely. A drug interaction study in healthy subjects has shown that ritonavir (a highly potent cytochrome P450 3A4 inhibitor) can greatly increase ...
The Effects of the Preferential 5
The Effects of the Preferential 5

... Furthermore, in their startle sequence only an interstimulus interval (ISI) of 100 ms was applied for the prepulse-pulse (PP) trials. Previously, it has been shown that PPI induced by PP combinations with ISIs of comparable duration, could be modulated by attention (Schell et al, 2000). Thus, attent ...
combining_loop_diuretic_with_thiazide_type_diuretic_for_HF
combining_loop_diuretic_with_thiazide_type_diuretic_for_HF

... edematous states date back more than 40 years to the early days of diuretic therapy (17). Despite more than 50 published reports, the experience is limited to 300 heart failure patients (Table 2) (17– 45), raising many questions about this potent diuretic combination. The aggregate body of literatur ...
KP National Cardiovascular Risk and Dyslipidemia Management
KP National Cardiovascular Risk and Dyslipidemia Management

... o Moderate-intensity statin therapy generally results in an average LDL–C reduction of 30 to <50% from the untreated baseline; o LDL–C levels and percent reduction are to be used only to assess response to therapy and adherence. They are not to be used as performance standards. ...
Document
Document

... •Given most often for opiate detoxification, and also for dependence on other drugs such as methamphetamine and cocaine. •Typically administered as a single oral dose in the range of 10 to 25 mg/kg of body weight. •Advantages attributed by those who have been treated with ibogaine are higher tolerab ...
practical approach to medical management of glaucoma
practical approach to medical management of glaucoma

... 35% REDUCTION • Prostaglandin analogues • Latanoprost 0.005% requires cold chain except new Latoprost RT. • Bimatoprost 0.03% most effective of all PG analogues but more side effects, hyperemia, trichomegaly, darkening of lids and iris pigmentation. • Travoprost 0.004% ...
Viral replication and new targets for antiviral therapy - HAL
Viral replication and new targets for antiviral therapy - HAL

... Chronic hepatitis B virus infections remain a major public health problem worldwide. The main clinical outcome is the development of chronic hepatitis, followed by liver cirrhosis and hepatocellular carcinoma. HBV is the first cause of hepatocellular carcinoma world wide (1, 2). HBV replication does ...
PDF
PDF

... improvements over wait-list control participants in levels of gambling severity, gambling urges, and emotional distress (Toneatto et al. 2014). Another recent study by Chen and colleagues (2014) administered a mindfulness treatment to 17 problem gamblers. The study highlighted a number of improvemen ...
An update on the management of chronic hepatitis C:
An update on the management of chronic hepatitis C:

... also be considered because progression to more advanced stages is associated with a reduced likelihood of SVR (5,6,33) but needs to be discussed on an individualized basis. Patients with extrahepatic manifestations of chronic hepatitis C including cryoglobulinemic vasculitis, porphyria cutanea tarda ...
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington

...  Timed-release preparations should not be crushed or chewed (cause gastric irritation) ...
FOI 204-1314 document 1 - Therapeutic Goods Administration (TGA)
FOI 204-1314 document 1 - Therapeutic Goods Administration (TGA)

... weeks for patients taking ZOLOFT compared to those on placebo. Therefore, the physician who elects to use ZOLOFT for extended periods should periodically reevaluate the long-term usefulness of the drug for the individual patient. Obsessive Compulsive Disorder (OCD) The efficacy and safety of ZOLOFT ...
QT variability during initial exposure to sotalol: experience based on
QT variability during initial exposure to sotalol: experience based on

... after sotalol administration. Among the patients who developed TdP, the number of sotalol doses administered before TdP onset were one dose for one TdP patient, two doses for three TdP patients, three and four doses for two TdP patients. In one patient, the TdP event was identified on an ICD because ...
Evaluation of Treatment>Resistant Schizophrenia
Evaluation of Treatment>Resistant Schizophrenia

... of treating schizophrenia (Revicki et al. 1990). These facts were the basis for the enthusiasm of clinicians following demonstration of clozapine's efficacy in inpatients with treatment-resistant schizophrenia (Kane et al. 1988). However, clozapine treatment is associated with substantial morbidity ...
Epilepsy
Epilepsy

... zonisamide, and pregabalin are also effective for treating partial seizures.  Lamotrigine and topiramate are effective as monotherapy and appear to be better tolerated than carbamazepine monotherapy particularly in elderly patients. ...
Prevalence and predictors of potential drug
Prevalence and predictors of potential drug

... During the study, prescriptions for 4467 patients were analyzed, 2558 clinical significant potential DDIs were identified among 1488 exposed patients (Table 1). Nine hundred and twenty one (36%) DDIs were rated as 1 and 1637 (64%) as 2, corresponding to 136 drug combinations. The mean number of DDIs ...
Pitavastatin compared with atorvastatin in primary
Pitavastatin compared with atorvastatin in primary

... Aims: To demonstrate the equivalence of pitavastatin compared with the most commonly used doses of atorvastatin in the reduction of LDL-C in primary hypercholesterolemia or combined dyslipidemia. Secondary objectives included the comparison of pitavastatin against the most commonly used doses of ato ...
Ibogaine in opioid detoxification
Ibogaine in opioid detoxification

... Opiate receptor antagonists bind to the opiate receptor and block signal transmission through the receptor ...
Hereditary Angioedema Caused By C1-Esterase Inhibitor
Hereditary Angioedema Caused By C1-Esterase Inhibitor

... attacks has been available in many countries for more than 30 years, until recently, there were no agents approved in the United States to treat HAE acutely. Therefore, prophylactic therapy is an integral part of HAE treatment in the United States and for selected patients worldwide. Long-term, or r ...
Hereditary Angioedema Caused By C1-Esterase Inhibitor Deficiency
Hereditary Angioedema Caused By C1-Esterase Inhibitor Deficiency

... attacks has been available in many countries for more than 30 years, until recently, there were no agents approved in the United States to treat HAE acutely. Therefore, prophylactic therapy is an integral part of HAE treatment in the United States and for selected patients worldwide. Long-term, or r ...
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Psychedelic therapy

Psychedelic therapy refers to therapeutic practices involving the use of psychedelic drugs, particularly serotonergic psychedelics such as LSD, psilocybin, DMT, mescaline, and 2C-B, primarily to assist psychotherapy. As an alternative to synonyms such as ""hallucinogen"", ""entheogen"", ""psychotomimetic"" and other functionally constructed names, the use of the term psychedelic (""mind-manifesting"") emphasizes that those who use these drugs as part of a therapeutic practice believe these drugs can facilitate beneficial exploration of the psyche. In contrast to conventional psychiatric medication which is taken by the patient regularly or as-needed, in psychedelic therapy, patients remain in an extended psychotherapy session during the acute activity of the drug and spend the night at the facility. In the sessions with the drug, therapists are nondirective and support the patient in exploring their inner experience. Patients participate in psychotherapy before the drug psychotherapy sessions to prepare them and after the drug psychotherapy to help them integrate their experiences with the drug.According to one Canadian study conducted in the early years of the 1960s, the greatest interest to the psychiatrist was the fact that LSD allowed for the ""illusional perception ('reperception') of the patient's original family figures (e.g. father, mother, parent surrogates and helpers, older siblings, grandparents and the like)"", typically experienced as distortions of the psychiatrist's face, body or activity. In technical terms, this was called ""perceptualizing the transference"".
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