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during fetal life - Journal of Clinical Pathology
during fetal life - Journal of Clinical Pathology

... weight and also in the ratio: these varied independently. Discussion Harvey (1628) noted that the ventricles during fetal life were different from those of the adult in that the right and left ventricles were almost equal -like 'the double kernels of a nut'. The present results demonstrate a relativ ...
Catecholaminergic Polymorphic Ventricular Tachycardia
Catecholaminergic Polymorphic Ventricular Tachycardia

... bidirectional VT [14] and it is recommended that the ICD be programmed with long detection times [15]. According to the current available Guidelines, implantation of an ICD with use of beta-blockers are considered to be a class I indication for patients with CPVT who are survivors of cardiac arrest ...
Ventricular haemodynamics in Python molurus: separation of
Ventricular haemodynamics in Python molurus: separation of

... lizards, and although unlikely to be common among squamates, it may exist in more species than previous acknowledged. Ventricular pressure separation, however, does not occur in the snakes Vipera berus, Natrix and Thamnophis (Johansen, 1959; Burggren, 1977) and large cardiac shunts have been reporte ...
Simultaneous 4-Chamber Strain - Circulation: Cardiovascular Imaging
Simultaneous 4-Chamber Strain - Circulation: Cardiovascular Imaging

... However, RV/LV peak strain ratio is given as 1.2 for the pulmonary hypertension patient, not much different from 1.1, the ratio reported for normals. Importantly, the independence of (left or right) atrial and ventricular LS is questionable. Because atrium and ventricle are tethered to each other in ...
Problems - Heart Failure Society of America
Problems - Heart Failure Society of America

... In some patients with a heart rhythm problem, an implantable device can be used to automatically monitor and correct a rhythm that is irregular or too fast or too slow. Clinicians program the device to read your heart’s rhythm all the time. It can correct rhythm problems using either small painless ...
Natriuretic peptide vs. clinical information for diagnosis of left
Natriuretic peptide vs. clinical information for diagnosis of left

... for each of the specific risk factors were multiplied by their actual values and then summed up. For example, individual patient risk score = (β1 × dyspnea at exertion × ankle swelling) + (β2 × coronary artery disease) + (β3 × diuretics). AUC of the clinical risk score indicates its diagnostic value ...
Pericardial Disease: Review Questions
Pericardial Disease: Review Questions

... tamponade from a noncompressive pericardial effusion. Rarely, the echocardiographic findings in tamponade reveal a moderate-to-large pericardial effusion, right atrial and right ventricular collapse, a plethoric vena cava, and, in approximately 25% of patients, the very specific finding of left atri ...
1 electrocardiography in two models of
1 electrocardiography in two models of

... observed myocardial changes could be induced as direct response of the elevated level of circulating isoproterenol at the time of experiments (Mészáros et al. 2001). Synthetic beta-adrenoceptor agonist isoproterenol leads to development of cardiac hypertrophy without increased blood pressure as a co ...
Cardiovascular Conditions: The Therapeutic Use of Beta
Cardiovascular Conditions: The Therapeutic Use of Beta

... is caused by an oxygen demand-supply mismatch and may be provoked by an increase in heart rate and blood pressure during exercise, typically in combination with an underlying restriction of coronary blood flow secondary to CAD. This could potentially lead to effort-related angina pectoris, acute myo ...
Heart - Dr Magrann
Heart - Dr Magrann

... The more you do aerobic exercise, the more branches of these arteries are formed between themselves (anastomosis), and the better the blood supply to the heart. When blood vessels fuse together where they meet it is said that they ANASTOMOSE. This is a safety mechanism that allows blood to get throu ...
The importance of long axis function
The importance of long axis function

... Since exercise has been shown as an independent cardio protective factor [28], it is of immense importance to offer suitable individually prescribed exercise. Hydrotherapy, exercise in warm water, (34°C), is an opportune exercise form [29] for patients suffering from disabilities that make exercise ...
Deakin Research Online - DRO
Deakin Research Online - DRO

... reduced blood pressure with an increase in heart rate. In such a situation, compensatory mechanisms may be failing (see Figure 4, page 37 for details about compensatory mechanisms). A sinus bradycardia may also be deliberately induced by drug therapies to reduce the heart’s workload after an AMI. Ot ...
Intra-aortic balloon pumps and continuous flow left ventricular assist
Intra-aortic balloon pumps and continuous flow left ventricular assist

... however, the preoperative benefits of IABP support are markedly diminished if not absent. Finally, it has been shown that counterpulsation with an IABP produces retrograde flow.6 Similarly, CF-LVADs operating in less than ideal hemodynamic situations can also generate retrograde flow.7 These adverse ...
Chest 1. Which one is not true for sternal angle? A. It is also termed
Chest 1. Which one is not true for sternal angle? A. It is also termed

... 39.Which of the following characteristic is not consistent with splitting of the S2? A. loss of synchronization in closure of aortic and pulmonary valves B. most clearly heard at the end of inspiration C. paradoxical split of S2 may be caused by right bundle branch block. D. fixed split of S2 is mai ...
S 132 Abstracts lion. Eur J Echocardiography Abstracts Supplement
S 132 Abstracts lion. Eur J Echocardiography Abstracts Supplement

... A. Wojlarowicz, M. Peregud-Pogorzelska, E. Plonska. Klinika Kardiologii PAM, ...
alert-06-ontarget-nejm_2008_358_online
alert-06-ontarget-nejm_2008_358_online

... myocardial infarction, stroke, or hospitalization for heart failure. The main secondary outcome was death from cardiovascular causes, myocardial infarction, or stroke, which was used as the primary outcome in the Heart Outcomes Prevention Evaluation (HOPE) trial. The P value is for the comparison wi ...
The module has been developed within the framework of the
The module has been developed within the framework of the

... as in an untrained person for a given intensity of Task, so the result of endurance training is that you reach your maximum heart rate at a higher level of exertion. At a given level of stress you can say that the lower the heart rate the higher the pulsatory volume and the fitter the person concern ...
causes of right ventricular failure
causes of right ventricular failure

... increased mortality compared to acutely decompensated LVF. It may also be an independent risk factor for morbidity and mortality in patients with left heart failure. Pulmonary hypertension (PH) in itself carries increased risk of adverse events (24%) and in-hospital deaths (9.7%); and PH and RHF is ...
pulmonary circulation
pulmonary circulation

... Ebstein: 1/20 000 or 0,5 % of cong. Heart defects ...
full text pdf
full text pdf

... and cyclists to improve their physical performance (4), strength and muscle mass (5). However, these individuals may take doses of up to 100 time higher doses than the therapeutic range, which leads to severe adverse effects on many organ systems (6). Nandrolone is a derivate of 19-nortestosterone a ...
Understanding your child`s heart Tetralogy of Fallot
Understanding your child`s heart Tetralogy of Fallot

... will tell you if your child should avoid any specific forms of exercise. Anyone who has had a Tetralogy repair operation will have an abnormal pulmonary valve which does not close effectively. This means that, after the right ventricle has pumped blood into the pulmonary artery, some of this blood l ...
(CRT-D) A - Grupo Akros
(CRT-D) A - Grupo Akros

... • No difference in 2-year survival between CRT and CRT-D patients. • In patients with Class IV symptoms in whom resynchronization is inadequate to restore clinical stability, the presence of a ICD often complicates the impending transition to end-of-life care. Lindenfeld et al. Circulation 2007 ...
Confocal Imaging of Early Heart Development in Xenopus laevis
Confocal Imaging of Early Heart Development in Xenopus laevis

... 1995; Grow and Krieg, 1998), PitX2 (Ryan et al., 1998), VEGF (Cleaver et al., 1997), Tbx5 (Horb and Thomsen, 1999), and Vg1 (Hyatt and Yost, 1998). The analysis of cardiac-specific promoters, like cardiac actin (Taylor et al., 1989), and expression studies using dominant negative proteins (Fu et al. ...
Gross Anatomy of the Heart in the Western Grey Kangaroo
Gross Anatomy of the Heart in the Western Grey Kangaroo

... and Valva aortae with their semilunares valvulas. The terminology given by the NAV to the cuspids and valves are according to their disposition in Macropus fuliginosus. In 1926, Grant & Regnier pointed out that in mammals, blood supply to the heart takes place through two coronary arteries, right an ...
12. What type of tissue carries small electrical currents to the muscles?
12. What type of tissue carries small electrical currents to the muscles?

... and nutrients to the cells and transports carbon dioxide and other wastes from the cells. For this to occur the supply of fresh blood needs to be regular. Under normal circumstances the rhythmic beating of the heart maintains a regular supply of blood to the tissues of the body. The rate at which th ...
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Heart failure



Heart failure (HF), often referred to as congestive heart failure (CHF), occurs when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs. The terms chronic heart failure (CHF) or congestive cardiac failure (CCF) are often used interchangeably with congestive heart failure. Signs and symptoms commonly include shortness of breath, excessive tiredness, and leg swelling. The shortness of breath is usually worse with exercise, while lying down, and may wake the person at night. A limited ability to exercise is also a common feature.Common causes of heart failure include coronary artery disease including a previous myocardial infarction (heart attack), high blood pressure, atrial fibrillation, valvular heart disease, excess alcohol use, infection, and cardiomyopathy of an unknown cause. These cause heart failure by changing either the structure or the functioning of the heart. There are two main types of heart failure: heart failure due to left ventricular dysfunction and heart failure with normal ejection fraction depending on if the ability of the left ventricle to contract is affected, or the heart's ability to relax. The severity of disease is usually graded by the degree of problems with exercise. Heart failure is not the same as myocardial infarction (in which part of the heart muscle dies) or cardiac arrest (in which blood flow stops altogether). Other diseases that may have symptoms similar to heart failure include obesity, kidney failure, liver problems, anemia and thyroid disease.The condition is diagnosed based on the history of the symptoms and a physical examination with confirmation by echocardiography. Blood tests, electrocardiography, and chest radiography may be useful to determine the underlying cause. Treatment depends on the severity and cause of the disease. In people with chronic stable mild heart failure, treatment commonly consists of lifestyle modifications such as stopping smoking, physical exercise, and dietary changes, as well as medications. In those with heart failure due to left ventricular dysfunction, angiotensin converting enzyme inhibitors or angiotensin receptor blockers along with beta blockers are recommended. For those with severe disease, aldosterone antagonists, or hydralazine plus a nitrate may be used. Diuretics are useful for preventing fluid retention. Sometimes, depending on the cause, an implanted device such as a pacemaker or an implantable cardiac defibrillator may be recommended. In some moderate or severe cases cardiac resynchronization therapy (CRT) may be suggested or cardiac contractility modulation may be of benefit. A ventricular assist device or occasionally a heart transplant may be recommended in those with severe disease despite all other measures.Heart failure is a common, costly, and potentially fatal condition. In developed countries, around 2% of adults have heart failure and in those over the age of 65, this increases to 6–10%. In the year after diagnosis the risk of death is about 35% after which it decreases to below 10% each year. This is similar to the risks with a number of types of cancer. In the United Kingdom the disease is the reason for 5% of emergency hospital admissions. Heart failure has been known since ancient times with the Ebers papyrus commenting on it around 1550 BCE.
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