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Familial Incidence of Atrial Septal Defect
Familial Incidence of Atrial Septal Defect

... showed a ventricular septal defect (VSD) and pulmonary stenosis, respectively, as associated defects. In our series ASD was the only defect (Table 1). The fifth sibling who died at two years of age in congestive heart failure had in all likelihood a complex heart abnormality. This is believed to be ...
Familial Incidence of Atrial Septal Defect
Familial Incidence of Atrial Septal Defect

... showed a ventricular septal defect (VSD) and pulmonary stenosis, respectively, as associated defects. In our series ASD was the only defect (Table 1). The fifth sibling who died at two years of age in congestive heart failure had in all likelihood a complex heart abnormality. This is believed to be ...
Recommendations for participation in competitive and leisure sports
Recommendations for participation in competitive and leisure sports

... Background Physical activity is important for patients with congenital heart disease. The aim of this paper is to provide a consensus document for participation in competitive or leisure sport activity in children and adults with congenital heart disease. Methods The recommendations are based on exp ...
C e n
C e n

... EXCADI (Exercise training in patients with coronary artery disease and diabetes). Based on the population from the ASCET study (vide supra) a new study was started aiming at evaluating the effect of systematic physical exercise training in a randomised trial including patients with documented corona ...
Longitudinal Common Carotid Artery Wall Motion
Longitudinal Common Carotid Artery Wall Motion

... Introduction .............................................................................................................................. 9  Cardiovascular disease ........................................................................................................................ 9  ...
Valvular Disease and Endocarditis - Ipswich-Year2-Med
Valvular Disease and Endocarditis - Ipswich-Year2-Med

...  Myocardium  focal interstitial inflammatory lesions; characterized by the pathognomonic Aschoff Nodule and diffuse interstitial myocarditis  may injure the myocytes directly or damage the conduction system  Endocardium  – valvulitis; inflammatory infiltration and edema in the stroma of the val ...
Assessment of Heart and Neck Vessels ANATOMY AND
Assessment of Heart and Neck Vessels ANATOMY AND

... The four cardiac valves are responsible for maintaining the forward flow of blood through the chambers of the heart. These valves open and close passively in response to pressure and volume changes within the cardiac chambers. The cardiac valves are classified into two types: atrioventricular (AV) v ...
Stress testing: A contribution from Dr Robert A. Bruce
Stress testing: A contribution from Dr Robert A. Bruce

... include testing for functional capacity, chronotropic incompetence, cardiac rehabilitation, valvular heart disease, hypertrophic cardiomyopathy, arrhythmias, and pacemaker evaluation.8-10 In addition, exercise testing has been combined with other modalities such as radionuclide imaging and echocardi ...
Impaired Myocardial Oxygenation Response to Stress in Patients
Impaired Myocardial Oxygenation Response to Stress in Patients

... Methods and Results-—Fifty-three subjects (23 subjects with CKD, 10 RT recipients, 10 hypertensive (HT) controls, and 10 normal controls without known coronary artery disease) underwent CMR scanning. All groups had cine and BOLD CMR at 3 T. The RT and HT groups also had late gadolinium CMR to assess ...
Why Are Patients With Chronic Obstructive Pulmonary
Why Are Patients With Chronic Obstructive Pulmonary

... elevated circulating CRP levels than the controls (Table 4). Participants with moderate airflow obstruction had smaller increases in circulating leukocyte, fibrinogen, and CRP levels. Mild airflow obstruction was not associated with elevations in any of these measurements. Lipid profiles among the 4 ...
TMT by Dr Sarma
TMT by Dr Sarma

... Multiple CV risk factors, Severe long standing DM, PVD, CKD are indications for ETT • Routinely in asymptomatic men/women without any CV Risk factors – ETT is not indicated • The false positive ETT results - unwanted tests and treatments preclude the use of ETT as a routine test. ...
When optimal BP control is difficult to achieve
When optimal BP control is difficult to achieve

... proof-of-principle trial.5 More recently, baroreflex activation therapy with an implantable device that activates the carotid baroreflex has been shown to reduce blood pressure by a mean of 22/12mmHg with minimal side effects.6 Indeed, once refined sufficiently, these novel methods hold promise for ...
Cardiac function in diabetic and non
Cardiac function in diabetic and non

... coronary angiography were studied. After obtaining medical history and anthropometrical data and prior to coronary angiography, arterial blood samples were obtained and the electrocardiogram was evaluated. During coronary angiography hemodynamic parameters and various left ventricular (LV) systolic ...
The Cardiovascular System
The Cardiovascular System

... The left and right ventricles pump blood into the systemic and pulmonary arterial trees, respectively. Cardiac output, the volume of blood ejected from each ventricle during 1 minute, is the product of heart rate and stroke volume. Stroke volume (the volume of blood ejected with each heartbeat) depe ...
myocardial bridge
myocardial bridge

... • Myocardial bridging is a frequent congenital anomaly with an incidence 5~86% at autopsy study. • 0.5~12 percent in angiography study • 30~80 percent in adults with hypertrophic cardiomyopathy • Myocardial bridging can exist in any coronary artery, but the LAD is the most commonly involved. ...
Magnetic Resonance Spectroscopy in Myocardial Disease
Magnetic Resonance Spectroscopy in Myocardial Disease

... free induction decay (FID), is converted into a magnetic resonance spectrum, which relates resonance frequency to signal intensity, by Fourier transformation. A number of signal-averaged acquisitions yield a magnetic resonance spectrum with sufficient signal-to-noise ratio. Correction factors for sa ...
Anomalous left coronary artery from the pulmonary artery presenting
Anomalous left coronary artery from the pulmonary artery presenting

... elderly stage of life is extremely rare. Insufficient collateral flow from the right coronary artery with a coronary steal from the left coronary artery into the pulmonary trunk result in malperfusion of the left ventricular myocardium, with the right coronary artery becoming large and tortuous. Pre ...
Baroreflex sensitivity changes with calcium antagonist
Baroreflex sensitivity changes with calcium antagonist

... and then held in that position for 3 min. The move from the supine to the tilted position took about 5 sec. During tilt BP and pulse interval were recorded from the Finapres, and forearm blood flow (FBF) in the right arm was measured with a mercury-in-silastic strain guage plethysmograph (QMC Medica ...
16-Heart
16-Heart

... Auscultation of the cardiac valves ...
A model-based approach for the evaluation of vagal and
A model-based approach for the evaluation of vagal and

... The baroreflex model was implemented under an object-oriented multiformalism modeling tool (M2SL) [16]. The first step of the identification was performed over a period P of 5 seconds. The results obtained are the following (the time parameters are expressed in seconds) : T = 0.13, K = 0.848, T = 0. ...
The Physiological and Evolutionary Significance of
The Physiological and Evolutionary Significance of

... Regulation of pulmonary and systemic vascular resistances results from changes in autonomic tone and the release of neurohumoral factors. In addition, these combined factors also influence heart rate, ventricular contractility, and ventricular blood volumes, which together can contribute to the size ...
Heart Failure in Children: Clinical Aspect and Management
Heart Failure in Children: Clinical Aspect and Management

... 70%, it occurred in the first year of life. Overall mortality in children with HF was 14%, more than double when compared to mortality in all heart disease patients.4 One large database from US found out that the heart failure in children (<18 years of age) was complicated by more frequent procedure ...
T
T

... Regulation of pulmonary and systemic vascular resistances results from changes in autonomic tone and the release of neurohumoral factors. In addition, these combined factors also influence heart rate, ventricular contractility, and ventricular blood volumes, which together can contribute to the size ...
The Association between the Pattern of Premature Ventricular
The Association between the Pattern of Premature Ventricular

... the bundle branch block pattern and electrical axis deviation: 1) the LBBB pattern without axis deviation (135 subjects), 2) the LBBB pattern with left axis deviation (29 subjects), 3) the right bundle branch block (RBBB) pattern without axis deviation (22 subjects) and 4) the RBBB pattern with left ...
Cardiac Magnetic Resonance Imaging and Computed Tomography
Cardiac Magnetic Resonance Imaging and Computed Tomography

... Data indicate that with 64-row MDCT scanners, under optimal conditions, high accuracy can be achieved for the detection of coronary artery stenoses greater than 50%.27–31 Importantly, in these and numerous other studies relating to CT coronary angiography, the negative predictive value for the prese ...
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Cardiovascular disease



Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. Cardiovascular disease includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs are stroke, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, atrial fibrillation, congenital heart disease, endocarditis, aortic aneurysms, peripheral artery disease and venous thrombosis.The underlying mechanisms vary depending on the disease in question. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, among others. High blood pressure results in 13% of CVD deaths, while tobacco results in 9%, diabetes 6%, lack of exercise 6% and obesity 5%. Rheumatic heart disease may follow untreated strep throat.It is estimated that 90% of CVD is preventable. Prevention of atherosclerosis is by decreasing risk factors through: healthy eating, exercise, avoidance of tobacco smoke and limiting alcohol intake. Treating high blood pressure and diabetes is also beneficial. Treating people who have strep throat with antibiotics can decrease the risk of rheumatic heart disease. The effect of the use of aspirin in people who are otherwise healthy is of unclear benefit. The United States Preventive Services Task Force recommends against its use for prevention in women less than 55 and men less than 45 years old; however, in those who are older it is recommends in some individuals. Treatment of those who have CVD improves outcomes.Cardiovascular diseases are the leading cause of death globally. This is true in all areas of the world except Africa. Together they resulted in 17.3 million deaths (31.5%) in 2013 up from 12.3 million (25.8%) in 1990. Deaths, at a given age, from CVD are more common and have been increasing in much of the developing world, while rates have declined in most of the developed world since the 1970s. Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. Most cardiovascular disease affects older adults. In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80, and 85% of people over 80 have CVD. The average age of death from coronary artery disease in the developed world is around 80 while it is around 68 in the developing world. Disease onset is typically seven to ten years earlier in men as compared to women.
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