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Gene Rearrangement in B- and T
Gene Rearrangement in B- and T

... four of six additional cases of non-Hodgkin’s lymphoma. It was not detected in 10 cases of acute myeloid leukemia nor in four cases of reactive lymphadenopathy. Detection of gene rearrangement by the polymerase chain reaction has a number of advantages over Southern blotting and is likely to become ...
EFFECT OF FSH β-SUB UNIT AND FSHR GENES
EFFECT OF FSH β-SUB UNIT AND FSHR GENES

... Bulls with mutation in exon 3 gene FSH β-sub unit identified have a lower fresh semen concentration, lower percentage of acrosome integrity in both fresh and frozen semen, lower sperm motility in frozen semen, poor quality and resistance on freeze treatment and lower fertility (Dai et al., 2009). Hu ...
MGF 110-13L/14L overlap
MGF 110-13L/14L overlap

... boxes to a given ortholog group is representative of how much of the ortholog is fused and which region. The fused ortholog groups are labelled along the deletion box connecting the fragments. The absence of a deletion box in a gene fusion indicates that the deletion that connects the two ORFs is on ...
Estimating the Form of Natural Selection on a Quantitative Trait
Estimating the Form of Natural Selection on a Quantitative Trait

... The relationshipto the moving average son. The main problem with these alterclarifiessome of the propertiesof the cubic nativedistributionsis thatfitnessis restrictspline. The spline provides a more local es- ed (O < ftz) < 1 in the binomial case, and timate of the regressionsurfacethan stan- 1(z) ' ...
A machine learning approach to gene expression data analysis
A machine learning approach to gene expression data analysis

... Colon tumor prediction: error as a function of the susbspace dimension ...
Gene silencing: Maintaining methylation patterns
Gene silencing: Maintaining methylation patterns

... although the hypermethylated superman alleles are stable in an antisense-METI background, most CG methylation, but not CNG methylation, is lost [13]. And lastly, in the absence of the PAI1 inverted repeat, methylation at the PAI2 locus occurs primarily at CG sites [2,8], and this methylation is abol ...
Overextension: The Extended Mind and Arguments from
Overextension: The Extended Mind and Arguments from

... consider its phenotype, the former is a thesis about what kind of entity cognitive scientists should study. The fact that evolutionary biologists might find it useful to see the extended effects of a gene as its phenotype seems, as such, to say nothing whatsoever about whether cognitive scientists s ...
Figure 15 - GEP Community Server
Figure 15 - GEP Community Server

... We can use this tool to identify genes that are expressed at specific developmental time points, tissues, treatments, cell types, or any combinations thereof. By default, genes with low or no expression according to the modENCODE gene expression scale are considered to be "off" while genes with mode ...
Theoretical perspectives on rapid evolutionary change
Theoretical perspectives on rapid evolutionary change

... is mixed, depending on the phenomenon being modeled. Often, the expected outcome of evolution under strong selection exhibits only minor quantitative discrepancies from what we would predict by increasing the strength of selection in weak selection approximations. In other cases, however, prediction ...
Expanded social fitness and HamiltonTs rule for kin, kith, and kind
Expanded social fitness and HamiltonTs rule for kin, kith, and kind

... the indirect effect of a partner βWG′.G, and a regression coefficient of relatedness βGG′. It is a neighbor-modulated fitness form of Hamilton’s rule, which totes up effect on each individual, but it can be rearranged under quite general conditions to an inclusive fitness form that switches all of the ...
Mar27-31
Mar27-31

... Rationale: If PKU carriers were more likely to have children than non-carriers because of the protective effects of the PKU gene, then over time, the disease-causing allele would increase and spread through the population. ...
Demographic history and climatic adaptation in ecological
Demographic history and climatic adaptation in ecological

... test, DHEW has been proved to be relatively insensitive to demography or population structure (Zeng et al. 2007). Nielsen et al. (2005) introduced the composite likelihood ratio method (CLR) to model the allele frequency spectrum to detect signals of selection. Genetic differentiation (FST) based me ...
Genomic Screening for Artificial Selection during Domestication and
Genomic Screening for Artificial Selection during Domestication and

... candidate region was narrowed within about 1 kb by a mapbased cloning strategy. Seven fixed single nucleotide polymorphisms (SNPs) were identified between maize landraces and teosintes: one nonsynonymous substitution (i.e. amino acid substitution) and six SNPs in the 5’ side of the promoter region. ...
Drosophila
Drosophila

... Specifically, we evaluate the pros and cons of each technique in a historical perspective. This review discuss important factors that should be taken into consideration for the selection of a strategy that best fits the specific needs of a gene knockout project. ...
Tutorial: RNA-Seq Analysis Part II (Tracks): Non-Specific
Tutorial: RNA-Seq Analysis Part II (Tracks): Non-Specific

... Running the same data set with the "Also map to inter-genic regions" option 15. We will now explore the differences between results obtained when running with the Map to gene regions only (fast) option and the Also map to inter-genic regions option: Again run an RNA-seq analysis of the "ESC-1" sampl ...
Integration of populations and differentiation of species
Integration of populations and differentiation of species

... isolation, and most of these are from animals. These ‘isolation genes’ can be divided into two groups, based on whether they contribute to pre or postzygotic isolation. Those involved in prezygotic isolation include: period, a clock gene which modifies song rhythm in Drosophila (Wheeler et al., 1991 ...
Genes regulated by TF
Genes regulated by TF

... However, some statistical massaging is done on this. Given a motif W, background nucleotide frequencies Wb and a site s, LLR score of s = Pr(s |W ) ...
Evolution In Silico: From Network Structure to Bifurcation Theory
Evolution In Silico: From Network Structure to Bifurcation Theory

... classical example of the camera eye [50]) and even convergent evolution of social structures (such as eusociality in insects and mole-rats [8]). These examples are especially interesting because if there is some reproducibility in nature, this means that there are some laws to discover to explain it ...
Estimates of Selection and Gene Flow From Measures of
Estimates of Selection and Gene Flow From Measures of

... and that u rz 2.6 km. In erato, the shapes of the clines agreed with that expected on the basis of dominance. Heliconius melpomene has a nearly coincident hybrid zone. In this species, cline widths at four major color pattern loci varied between 1 1.7 and 13.4km. Pairwise gametic correlations peaked ...
Genes regulated by TF
Genes regulated by TF

... However, some statistical massaging is done on this. Given a motif W, background nucleotide frequencies Wb and a site s, LLR score of s = Pr(s |W ) ...
Pisum Genetics Volume 26 1994 Preface 1 PGA "Pisum Genetics
Pisum Genetics Volume 26 1994 Preface 1 PGA "Pisum Genetics

... Length should generally be kept within the range of 1-4 journal pages but longer papers will be considered on their merits. Research reports and reviews are subjected to peer review and revision if necessary. Research reports should contain original work not currently submitted to any other journal. ...
How to Carry Out the Adaptationist Program? Ernst Mayr The
How to Carry Out the Adaptationist Program? Ernst Mayr The

... At this point it may be useful to look at the concept of adaptation from a historical point of view. When Darwi11introduced natural selection as the agent of adaptation, he did so as a replacement for supernatural design. Design, as conceived by the natural theologians, had to be perfect, for it was ...
Mayr - Eric L. Peters` Home Page
Mayr - Eric L. Peters` Home Page

... At this point it may be useful to look at the concept of adaptation from a historical point of view. When Darwi11introduced natural selection as the agent of adaptation, he did so as a replacement for supernatural design. Design, as conceived by the natural theologians, had to be perfect, for it was ...
We need an optimality criterion to choose a best estimate (tree
We need an optimality criterion to choose a best estimate (tree

... will also be too variable to analyze. It may even approach a random distribution! • Therefore, what is really needed is a gene which evolves at a rate that provides a good balance between conservation and variation. Or better yet, resolve splits of different ages by sequencing more than one gene ...
How Evolution Works - The Teacher-Friendly Guide™ to Evolution
How Evolution Works - The Teacher-Friendly Guide™ to Evolution

... 1. Natural selection has an inevitable result - False. An important basis of natural selection is that variation is random and selection is natural, without intervention or predetermination. Natural selection has no direction. It is simply the process by which random variations that give an individu ...
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The Selfish Gene

The Selfish Gene is a book on evolution by Richard Dawkins, published in 1976. It builds upon the principal theory of George C. Williams's first book Adaptation and Natural Selection. Dawkins used the term ""selfish gene"" as a way of expressing the gene-centred view of evolution as opposed to the views focused on the organism and the group, popularising ideas developed during the 1960s by W. D. Hamilton and others. From the gene-centred view follows that the more two individuals are genetically related, the more sense (at the level of the genes) it makes for them to behave selflessly with each other. This should not be confused with misuse of the term along the lines of a selfishness gene.An organism is expected to evolve to maximise its inclusive fitness—the number of copies of its genes passed on globally (rather than by a particular individual). As a result, populations will tend towards an evolutionarily stable strategy. The book also coins the term meme for a unit of human cultural evolution analogous to the gene, suggesting that such ""selfish"" replication may also model human culture, in a different sense. Memetics has become the subject of many studies since the publication of the book.In the foreword to the book's 30th-anniversary edition, Dawkins said he ""can readily see that [the book's title] might give an inadequate impression of its contents"" and in retrospect thinks he should have taken Tom Maschler's advice and called the book The Immortal Gene.
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