• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Protein Surgery Increases Protein Demands in the Body Getting
Protein Surgery Increases Protein Demands in the Body Getting

... Getting extra protein is especially important after surgery because the body needs it to make immune cells and antibodies, to reduce inflammation and to mend the wound at the site of incision. Without enough protein from food, the body must make its own by breaking down muscle and organ tissue, sapp ...
NUTRILITE Protein
NUTRILITE Protein

... may not be able to consume sufficient protein from their daily diet due to reduced ability to chew meats or lactose intolerance ...
Proteins containing unusual amino acid sequences
Proteins containing unusual amino acid sequences

... Similarly, in bacteria there are simple elements, such as -Asp-Asn-Pro- in staphylococcal protease, as well as much more complex ones like in the icenucleation proteins [6]. Possible explanations for the occurrence of repeating elements in the surface proteins of protozoal parasites are discussed by ...
The Chemistry of the cell
The Chemistry of the cell

... other molecules covalently attached to certain amino acids. Most of this is done in the endoplasmic reticulum. • Many proteins are targeted to specific organelles within the cell. Targeting is accomplished through “signal sequences” on the polypeptide. In the case of proteins that go into the endopl ...
Histidine and tyrosine phosphorylation in pea mitochondria
Histidine and tyrosine phosphorylation in pea mitochondria

... conserved histidine upon activation.The environmental signal is then communicated to the soluble regulator protein, a transcription factor, with an aspartate phosphorylation site. Protein kinase activity has also been detected in the chloroplasts (reviewed in [3]) and mitochondria [4 8] of eukaryoti ...
Enhanced Detection of Host-Cell Proteins in
Enhanced Detection of Host-Cell Proteins in

... Sub-ppm level HCP detection was achieved, i.e., 58 HCPs were detected ≤ 10 fmol with 3 unique peptides/protein. ...
as PDF
as PDF

... of hydrophobic residues to the aqueous surrounding, and prevents the molecule from assuming a globular protein structure (Figure 1). Instead, it drives the molecules to undergo dimerization, resulting in highly stable dimeric proteins with a butterfly-shape structure. The cysteine knot structural mo ...
Neural activity
Neural activity

... It is unlikely that sufficient neurotransmitter at one astrocytically-enveloped synapse could provoke a calcium wave. An individual Astrocyte, however, can envelop many synapses in vivo. Exposure to neurotransmitters at multiple synapses is most likely the necessary factor in calcium wave production ...
Proteins Animal By-Products Seed By
Proteins Animal By-Products Seed By

... amino acids have been absorbed by the small intestine, they enter to blood stream and are carried to the liver. The liver can convert amino acids to fats or glucose, both of which can be used for energy. However, the animal’s body uses amino acids for energy only if other energy sources are depleted ...
A CHASE domain containing protein kinase OsCRL4
A CHASE domain containing protein kinase OsCRL4

... responses (Kakimoto, 1996) and that a set of response regulators of two-component systems can be induced by cytokinin (Brandstatter and Kieber, 1998; Sakakibara et al., 1998). Two-component systems use a histidine kinase as an environmental sensor and rely on a phosphorelay for signal transduction. ...
functional and structural complexity of signal transduction via g
functional and structural complexity of signal transduction via g

... GUDERMANN, SCHÖNEBERG & SCHULTZ ...
L859F Mutation in Androgen Receptor Gene Results in Complete
L859F Mutation in Androgen Receptor Gene Results in Complete

... boiled for 10 minutes in a water bath according to the method of Laemmli (1970). The cell lysate was centrifuged at 10 000 rpm for 3 minutes (Biofuge pico, Heraeus Instruments, Hanau, Germany) and supernatant collected. Protein content of each lysate was estimated in the supernatant by Amido Black m ...
Unknown function, JCSG
Unknown function, JCSG

... provides better templates for modeling other proteins. The comparative structural analysis presented here provides experimental verification of the validity of this approach. •The structures for the proteins HP10645A and HP10645E suggest that they should be assigned to PF00246 in PfamA instead of th ...
The Special Senses - Central High School
The Special Senses - Central High School

... Taste • From facial nerves to medulla oblongata, then thalamus, then sensory cortex • Afferent impulses of taste also stimulate reflexes which promote digestion ...
Use of Cell-Free Protein Production Platform for X
Use of Cell-Free Protein Production Platform for X

... cell-free translation (PDB 3KDF, see below) had a better resolution of 2 Å. An important feature of this work was that the open nature of cell-free translation was successfully exploited to assemble target solved by X-ray crystallography. A third PDB entry, 3KEV, represents our first de novo cell-fr ...
Protein Synthesis and Transport within the Cell
Protein Synthesis and Transport within the Cell

... Secretory activities – two types Constituitive Transported from site of synthesis and secreted continuously ...
lecture09_14Class
lecture09_14Class

... The probability of observing a residue which belongs to an α-helix followed by a residue belonging to a turn = 0.15 Table built according to large database of known secondary structures ...
BS3 Crosslinking
BS3 Crosslinking

... previously (Grosshans et al., 2001, 2002; Conrad et al., 2008). BS3 is a membrane-impermeable agent, which selectively crosslinks cell-surface proteins to form high-molecular-mass aggregates. Because intracellular proteins are not modified, they retain normal molecular mass. This enables surface and ...
L. RECEPTOR-LIGAND DISSOCIATION Simple Equilibrium Binding
L. RECEPTOR-LIGAND DISSOCIATION Simple Equilibrium Binding

... number of subunits present. In a dimer, the maximum Hill coefficient is two – in a tetramer, it is four. Etc. If one has a dimeric receptor with a Hill coefficient of 1.5, then that means there is significant increase in affinity for the second ligand, but not enough to guarantee that the second eq ...
Lecture 5 The Cell membrane and Membrane Proteins The cell
Lecture 5 The Cell membrane and Membrane Proteins The cell

... Sodium-­‐potassium  pump  =  electrogenic  pump  =  Generates  a  voltage  across  the  membrane   -­‐More  nega4vely  charged  inside  a  cell  than  outside  -­‐creates  an  “electrochemical”  gradient   ...
Protein And Amino Acids - Manasquan Public Schools
Protein And Amino Acids - Manasquan Public Schools

...  The body’s fluids are contained inside the blood vessels (intravascular), within the cells (intracellular), and between the cells (intercellular).  Fluids flow freely between these compartments. Cells can’t move these fluids, instead they manufacture proteins.  Proteins help regulate the composi ...
Protein
Protein

... a ‘pump’ to maintain this difference Sodium-Potassium Pump ...
Protein synthesis
Protein synthesis

... • The uncharged tRNA leaves the P site • The peptidyl-tRNA moves from A site to the P site • The ribosome moves three nucleotides along the mRNA • This process requires EF-G (translocase) and GTP ...
BP DB (Recovered) - Base Pair Biotechnologies
BP DB (Recovered) - Base Pair Biotechnologies

... catalog aptamers to academic, commercial, and government researchers for a variety of applications. To support their efforts we provide this series of aptamer best practices as a introduction to their use. Additional assistance is provided as needed. ...
4.2 How to get other molecules across membranes
4.2 How to get other molecules across membranes

... family of transporters. There are 7 different, but related, proteins. But, only four (GLUT1-4) are known to be involved in glucose transport. All GLUT proteins share a set of similar structural features and are all about 500 amino acids in length (giving them a predicted molecular weight of about 55 ...
< 1 ... 212 213 214 215 216 217 218 219 220 ... 354 >

G protein–coupled receptor



G protein–coupled receptors (GPCRs), also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times.G protein–coupled receptors are found only in eukaryotes, including yeast, choanoflagellates, and animals. The ligands that bind and activate these receptors include light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters, and vary in size from small molecules to peptides to large proteins. G protein–coupled receptors are involved in many diseases, and are also the target of approximately 40% of all modern medicinal drugs. Two of the United States's top five selling drugs (Hydrocodone and Lisinopril) act by targeting a G protein–coupled receptor. The 2012 Nobel Prize in Chemistry was awarded to Brian Kobilka and Robert Lefkowitz for their work that was ""crucial for understanding how G protein–coupled receptors function."". There have been at least seven other Nobel Prizes awarded for some aspect of G protein–mediated signaling.There are two principal signal transduction pathways involving the G protein–coupled receptors: the cAMP signal pathway and the phosphatidylinositol signal pathway. When a ligand binds to the GPCR it causes a conformational change in the GPCR, which allows it to act as a guanine nucleotide exchange factor (GEF). The GPCR can then activate an associated G protein by exchanging its bound GDP for a GTP. The G protein's α subunit, together with the bound GTP, can then dissociate from the β and γ subunits to further affect intracellular signaling proteins or target functional proteins directly depending on the α subunit type (Gαs, Gαi/o, Gαq/11, Gα12/13).
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report