Captopril Ameliorates Myocarditis in Acute
... mation, fibrosis, and necrosis in infected mice compared with untreated controls at 21 days after infection (Table 3), but did not further reduce the severity of myocarditis. Increasing the dose of captopril decreased body weight and heart weight in a dose-dependent manner, but had no significant ef ...
... mation, fibrosis, and necrosis in infected mice compared with untreated controls at 21 days after infection (Table 3), but did not further reduce the severity of myocarditis. Increasing the dose of captopril decreased body weight and heart weight in a dose-dependent manner, but had no significant ef ...
The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin
... The oral absorption and disposition of digoxin is markedly dependent upon the interaction it has with the ATP-dependent export pump P-glycoprotein (Pgp, ABCB1). Numerous in vitro systems have been used to investigate the secretory transport of digoxin by Pgp [1,2]. Because digoxin displays a very na ...
... The oral absorption and disposition of digoxin is markedly dependent upon the interaction it has with the ATP-dependent export pump P-glycoprotein (Pgp, ABCB1). Numerous in vitro systems have been used to investigate the secretory transport of digoxin by Pgp [1,2]. Because digoxin displays a very na ...
Cotoneaster Care Sheet
... broadleaf shrub that has small leaves and some very good characteristics that make them perfect bonsai specimens. In the Rose (Rosaceae) family, they are tolerant of heavy pruning and human error. This native of China and the Himalayas has a multi-seasonal appeal. There are many varieties of cotonea ...
... broadleaf shrub that has small leaves and some very good characteristics that make them perfect bonsai specimens. In the Rose (Rosaceae) family, they are tolerant of heavy pruning and human error. This native of China and the Himalayas has a multi-seasonal appeal. There are many varieties of cotonea ...
Plant Profile, Phytochemistry and Pharmacology of Ashoka (Saraca
... uterine muscles and this makes it effective as a uterine tonic for irregular menstrual cycles and miscarriage. Ksheerapaka of 6 gm bark powder of Ashoka is usuful in Pradara roga of females; also this ksheerpaka is effective in uterine inertia, uterine pain, urinary calculus, and dysuria. In pain lo ...
... uterine muscles and this makes it effective as a uterine tonic for irregular menstrual cycles and miscarriage. Ksheerapaka of 6 gm bark powder of Ashoka is usuful in Pradara roga of females; also this ksheerpaka is effective in uterine inertia, uterine pain, urinary calculus, and dysuria. In pain lo ...
IOSR Journal of Pharmacy and Biological Sciences (IOSRJPBS)
... lipid peroxidation processes, free- radical- related reactions and the development of a variety of pathological states [1]. It is well established that lipid peroxidation is the deleterious result of free radical reactions leading to disruption of biomembranes and subsequent dysfunction of cells and ...
... lipid peroxidation processes, free- radical- related reactions and the development of a variety of pathological states [1]. It is well established that lipid peroxidation is the deleterious result of free radical reactions leading to disruption of biomembranes and subsequent dysfunction of cells and ...
ii. immunosuppressive drugs - The University of Tennessee, Knoxville
... obesity. Enhanced insulin secretion is induced in vitro by agouti effects on calcium influx into islet cells. Preliminary testing of insulin producing pancreatic cells has shown that exposure to high doses of an immunosuppressive drug tacrolimus (FK506) altered the secretion of insulin. The hypothes ...
... obesity. Enhanced insulin secretion is induced in vitro by agouti effects on calcium influx into islet cells. Preliminary testing of insulin producing pancreatic cells has shown that exposure to high doses of an immunosuppressive drug tacrolimus (FK506) altered the secretion of insulin. The hypothes ...
List of Figures - The University of Tennessee, Knoxville
... obesity. Enhanced insulin secretion is induced in vitro by agouti effects on calcium influx into islet cells. Preliminary testing of insulin producing pancreatic cells has shown that exposure to high doses of an immunosuppressive drug tacrolimus (FK506) altered the secretion of insulin. The hypothes ...
... obesity. Enhanced insulin secretion is induced in vitro by agouti effects on calcium influx into islet cells. Preliminary testing of insulin producing pancreatic cells has shown that exposure to high doses of an immunosuppressive drug tacrolimus (FK506) altered the secretion of insulin. The hypothes ...
Medication Administration Risks
... administration issues in order to reduce the need for pre-poured medications. This may include reviewing procedures, selecting better medication packaging options, or adjusting staffing patterns. Right documentation is the first safety principle added to the original ‘5 rights of medication administ ...
... administration issues in order to reduce the need for pre-poured medications. This may include reviewing procedures, selecting better medication packaging options, or adjusting staffing patterns. Right documentation is the first safety principle added to the original ‘5 rights of medication administ ...
International Journal of Pharmaceutical Sciences and Drug Research 2014; 6(4): 334-340
... Hence to exploit its potential use prompted the present study to investigate the leaves of this plant with clear scientific protocol. The leaf extract of Costus pictus contain bioactive compounds such as flavonoid, phenolic compound, tannin, triterpenes, sterols, alkaloids and vitamins. The extract ...
... Hence to exploit its potential use prompted the present study to investigate the leaves of this plant with clear scientific protocol. The leaf extract of Costus pictus contain bioactive compounds such as flavonoid, phenolic compound, tannin, triterpenes, sterols, alkaloids and vitamins. The extract ...
Antihistamine Toxicosis
... antihistamines are small lipophilic molecules, so they may cause adverse effects because of their cholinergic activity and their ability to cross the blood-brain barrier. Second-generation antihistamines are more lipophobic than first-generation antihistamines and are thought to lack central nervous ...
... antihistamines are small lipophilic molecules, so they may cause adverse effects because of their cholinergic activity and their ability to cross the blood-brain barrier. Second-generation antihistamines are more lipophobic than first-generation antihistamines and are thought to lack central nervous ...
4-aminoquinolines as Antimalarial Drugs
... 2009), which became first in class of the quinine-based drugs termed the 4-aminoquinolines. The structure of 4-aminoquinoline (Figure 1) is based on the natural crystalline alkaloid quinine, found in Cinchona bark. While chloroquine was not the first synthetic antimalarial, it surpassed early compou ...
... 2009), which became first in class of the quinine-based drugs termed the 4-aminoquinolines. The structure of 4-aminoquinoline (Figure 1) is based on the natural crystalline alkaloid quinine, found in Cinchona bark. While chloroquine was not the first synthetic antimalarial, it surpassed early compou ...
Medication Safety in the Neonatal Intensive Care Unit
... NICU patients often have long hospital stays, which increases exposure to medications and medication errors. In premature infants, the immaturity of developing body systems affects the absorption, distribution, metabolism, and excretion of drugs, and therefore, an exponential risk for medication err ...
... NICU patients often have long hospital stays, which increases exposure to medications and medication errors. In premature infants, the immaturity of developing body systems affects the absorption, distribution, metabolism, and excretion of drugs, and therefore, an exponential risk for medication err ...
Opioid and Cannabinoid Modulation of Precipitated Withdrawal in
... 30 g, and were housed six animals per cage in an American association for the Accreditation of Laboratory Animal Care-approved facility. The study was approved by the Institutional Animal Care and Use Committee at Virginia Commonwealth University. Mice were given unlimited access to food and water a ...
... 30 g, and were housed six animals per cage in an American association for the Accreditation of Laboratory Animal Care-approved facility. The study was approved by the Institutional Animal Care and Use Committee at Virginia Commonwealth University. Mice were given unlimited access to food and water a ...
antibiotics in farm animal production
... in food or through the environment. When these bacteria cause illnesses in people they are more difficult to treat and the resistant bacteria spread further by being transmitted between people. In addition, the genes for resistance can be passed from resistant bacteria to other bacteria that are als ...
... in food or through the environment. When these bacteria cause illnesses in people they are more difficult to treat and the resistant bacteria spread further by being transmitted between people. In addition, the genes for resistance can be passed from resistant bacteria to other bacteria that are als ...
antibiotics in animal farming
... The therapeutic treatment of individual sick animals with antibiotic drugs is often essential. It relieves suffering and returns them to economic production. But during the 20th century the use of antibiotics in farm animals rapidly expanded to include uses that are, to a greater or lesser degree, n ...
... The therapeutic treatment of individual sick animals with antibiotic drugs is often essential. It relieves suffering and returns them to economic production. But during the 20th century the use of antibiotics in farm animals rapidly expanded to include uses that are, to a greater or lesser degree, n ...
MEDICATION MANAGEMENT
... medications dispensed to a resident.) (4) All PRN medication dispensing is to be documented in the same manner, with the reason for the dispensing documented on the back of the MARs as well as in the progress note. (5) All discontinued (DC’d) medications must be indicated on the correct date and a l ...
... medications dispensed to a resident.) (4) All PRN medication dispensing is to be documented in the same manner, with the reason for the dispensing documented on the back of the MARs as well as in the progress note. (5) All discontinued (DC’d) medications must be indicated on the correct date and a l ...
ANTIHYPERGLYCEMIC, ANTIHYPERLIPIDAEMIC AND ANTIOXIDANT ACTIVITY OF DIABETIC RATS CYNOGLOSSUM ZEYLANICUM
... to be useful in diabetes worldwide and have been used empirically in antidiabetic and antihyperlipidaemic remedies. The antihyperglycemic effect of these plants are of their ability to restore the function of pancreatic tissues by increasing insulin output or inhibit the intestinal absorption of glu ...
... to be useful in diabetes worldwide and have been used empirically in antidiabetic and antihyperlipidaemic remedies. The antihyperglycemic effect of these plants are of their ability to restore the function of pancreatic tissues by increasing insulin output or inhibit the intestinal absorption of glu ...
Anti-inflammatory and Analgesic Activity of Methanolic Extract of
... ABSTRACT Rhodiola rosea L. (Crassulaceae) have been used as traditional medicines that can increase someone’s physical strength, work productivity, longevity and resistance to high altitude sickness, fatigue, depression, anaemia, gastrointestinal ailments, infections, and nervous system disorders. T ...
... ABSTRACT Rhodiola rosea L. (Crassulaceae) have been used as traditional medicines that can increase someone’s physical strength, work productivity, longevity and resistance to high altitude sickness, fatigue, depression, anaemia, gastrointestinal ailments, infections, and nervous system disorders. T ...
Evaluation of rat ultrasonic vocalizations as predictors of the
... showed a trend towards emitting fewer 50 kHz USVs in the drug-paired compartment [F(2,22)=3.25, P=0.06]. Specifically, animals conditioned with the high [0.36±0.23; t(17)=2.61, P<0.05] but not the low dose of NAL (3.87±1.23) emitted fewer 50 kHz USVs in the drug-paired compartment, relative to VEH-c ...
... showed a trend towards emitting fewer 50 kHz USVs in the drug-paired compartment [F(2,22)=3.25, P=0.06]. Specifically, animals conditioned with the high [0.36±0.23; t(17)=2.61, P<0.05] but not the low dose of NAL (3.87±1.23) emitted fewer 50 kHz USVs in the drug-paired compartment, relative to VEH-c ...
Pharmacologyonline 3: 201-216 (2006) Kumarappan et al. CT
... Plants have yielded many widely used drugs and the current treatment of inflammatory conditions as well as infectious diseases relies heavily on natural products (1). Over 100 chemical substances that are considered to be important drugs that are either currently in use or have been widely used in t ...
... Plants have yielded many widely used drugs and the current treatment of inflammatory conditions as well as infectious diseases relies heavily on natural products (1). Over 100 chemical substances that are considered to be important drugs that are either currently in use or have been widely used in t ...
Abstract: Long Project
... Image 1: http://media-2.web.britannica.com/eb-media/37/96837-004-AAC9A5BB.jpg ,Image 2: http://www.pharmoscorp.com/development/nanotechnology.html ,Image 3: http://radioweblogs.com/0105910/images/nanoparticles.jpg , Image 4: http://www.rsc.org/ejga/SM/2008/b807696k-ga.gif ...
... Image 1: http://media-2.web.britannica.com/eb-media/37/96837-004-AAC9A5BB.jpg ,Image 2: http://www.pharmoscorp.com/development/nanotechnology.html ,Image 3: http://radioweblogs.com/0105910/images/nanoparticles.jpg , Image 4: http://www.rsc.org/ejga/SM/2008/b807696k-ga.gif ...
“PODOPHYLLUM HEXANDRUM” Review Article PARVAIZ H QAZI*, ABILA RASHID, SAMI A SHAWL
... podophyllotoxinglycoside, kaempferol and kaempferol-3-glucoside. The rhizomes and roots of the plant contain anti tumor lignans such as podophyllotoxin, 4’-demethyl podophyllotoxin and podophyllotoxin 4-O-glucoside 14-15. Among these lignans, podophyllotoxin is most important for its use in the synt ...
... podophyllotoxinglycoside, kaempferol and kaempferol-3-glucoside. The rhizomes and roots of the plant contain anti tumor lignans such as podophyllotoxin, 4’-demethyl podophyllotoxin and podophyllotoxin 4-O-glucoside 14-15. Among these lignans, podophyllotoxin is most important for its use in the synt ...
Phytochemistry, traditional uses and cancer
... Chyavanaprasha. More than anything, it may be called as "King of Rasayana" [rejuvenation], owing to its multiple health benefits. Phyllanthus emblica or Indian gooseberry (Amla) possesses a vastethnomedical history and represents a phytochemical reservoir of heuristic medicinal value. It is one of t ...
... Chyavanaprasha. More than anything, it may be called as "King of Rasayana" [rejuvenation], owing to its multiple health benefits. Phyllanthus emblica or Indian gooseberry (Amla) possesses a vastethnomedical history and represents a phytochemical reservoir of heuristic medicinal value. It is one of t ...
Microinjection of GABAergic agents into the anterior nucleus of the
... similar (even with the AM being relatively far from the thalamic/ ventricular border), (3) side effects in animals receiving ventricular muscimol were different from those in the AN groups, (4) ventricular muscimol injections were not protective against seizures and SE, even at toxic doses. Altogeth ...
... similar (even with the AM being relatively far from the thalamic/ ventricular border), (3) side effects in animals receiving ventricular muscimol were different from those in the AN groups, (4) ventricular muscimol injections were not protective against seizures and SE, even at toxic doses. Altogeth ...
TECTONA GRANDIS Research Article NEHA KHERA
... considered as a major constituent in many folklore medicines. Medicinally it has various pharmacological activities like antibacterial, antioxidant, antifungal, anti-inflammatory, anti-pyretic, analgesic, anti-diuretic, and hypoglycemic. Further studies reveal the presence of carbohydrate, tannins, ...
... considered as a major constituent in many folklore medicines. Medicinally it has various pharmacological activities like antibacterial, antioxidant, antifungal, anti-inflammatory, anti-pyretic, analgesic, anti-diuretic, and hypoglycemic. Further studies reveal the presence of carbohydrate, tannins, ...
Zoopharmacognosy
Zoopharmacognosy is a behaviour in which non-human animals apparently self-medicate by selecting and ingesting or topically applying plants, soils, insects, and psychoactive drugs to treat or prevent disease.The term derives from roots zoo (""animal""), pharma (""drug""), and gnosy (""knowing"") and was proposed in 1993. The term gained popularity from academic works and in a book by Cindy Engel called Wild Health: How Animals Keep Themselves Well and What We Can Learn from Them.A well-known example of zoopharmacognosy occurs when dogs eat grass to induce vomiting. However, the behaviour is more diverse than this. Animals ingest non-foods such as clay, charcoal and even toxic plants, apparently to prevent parasitic infestation or poisoning. Self-medication in wild animals remains a controversial subject because evidence is mostly circumstantial or anecdotal, however, there are many purported examples. The methods by which animals self-medicate vary, but can be classified according to function as prophylactic (preventative, before infection or poisoning) or therapeutic (after infection, to combat the pathogen or poisoning).