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Inappropriate affect
Inappropriate affect

... • The four fundamental features are still referred to as Bleuler’s Four A’s: • Association (thought disorder) • Affect (emotional disturbance) • Ambivalence (inability to make or follow through on decisions) • Autism (withdrawal from reality) ...
pain manifestations in schizophrenia - clinical and
pain manifestations in schizophrenia - clinical and

... The gathering of the reports included in this minireview covered articles from inception until 10th March 2015, for the following key-words “pain in schizophrenia”; ”pain phenomenon and schizophrenic disease”; ”pain perception in schizophrenia”; “pain vs. schizophrenia”. Cross references were also c ...
ECT_01 dec 2015
ECT_01 dec 2015

... practice were under way ...
i An investigation of the link between cortical inhibition
i An investigation of the link between cortical inhibition

... GABA have been identified in the brains of those with schizophrenia. Studies examining the nature of these differences have given variable results depending on the type of patient group, medication and the brain region where in vivo MRS GABA was measured. Chapter 5 of this thesis utilises the noninv ...
Effects of vitamins, fatty acids, minerals, and other dietary
Effects of vitamins, fatty acids, minerals, and other dietary

... Report:  ISBN 978-82-8121-431-6 ISSN 1890-1298 ...
Introduction to Magellan`s Adopted Clinical Practice Guidelines For
Introduction to Magellan`s Adopted Clinical Practice Guidelines For

... likelihood of receiving a prescription of an antipsychotic as well as a lower likelihood of receiving more than one antipsychotic or receiving a first-generation antipsychotic (FGA). African Americans were also more likely to receive prescriptions for first-generation antipsychotics. Researchers no ...
Childhood trauma, psychosis and schizophrenia: a
Childhood trauma, psychosis and schizophrenia: a

... which childhood trauma increases risk for psychosis merit attention. Integration of these different levels of analysis may stimulate a more genuinely integrated bio-psycho-social model of psychosis than currently prevails. Clinical implications include the need for staff training in asking about abuse ...
Childhood trauma, psychosis and schizophrenia: a literature review
Childhood trauma, psychosis and schizophrenia: a literature review

... which childhood trauma increases risk for psychosis merit attention. Integration of these different levels of analysis may stimulate a more genuinely integrated bio-psycho-social model of psychosis than currently prevails. Clinical implications include the need for staff training in asking about abuse ...
Guidelines for Biological Treatment of Schizophrenia, Part 2
Guidelines for Biological Treatment of Schizophrenia, Part 2

... meaningful. They are intended to be used by all physicians diagnosing and treating people suffering from schizophrenia. Based on the first version of these guidelines, a systematic review of the MEDLINE/PUBMED database and the Cochrane Library, in addition to data extraction from national treatment ...
Robert Schumann - Northern State University
Robert Schumann - Northern State University

... writer, which led to his great interest in literature 3. Studied law at Leipzig University. 4. At twenty, decided to become a piano virtuoso. This goal became impossible when he developed serious problems with his right hand which were not helped by medical treatments or by a device he may have used ...
Document
Document

... • Heritability of schizophrenia is only 48% for identical twins, so nongenetic factors must contribute Psychosocial contributors: 1. Diathesis-stress model = a hypothesis about the cause of certain disorders, such as schizophrenia, which suggests that people inherit a predisposition (or “diathesis”) ...
schizophrenia
schizophrenia

... Whatever happened to all those things you were planning to do; the dreams, the hopes and the expectations? Was there really a time when the future didn’t seem so challenging, so difficult and so bleak? This is the harsh reality of schizophrenia. It is a condition that affects people in the prime of ...
Professor Paul Lysaker 7. maj 2015 – ISPS
Professor Paul Lysaker 7. maj 2015 – ISPS

... Participants recognize that they are not necessarily the center of other people’s mental activities (their thoughts, feelings, and emotions) and/or that some of the actions of other people stem from goals and reasons etc. which are not related to the participant. Participants recognize that others c ...
The relationship between trauma and psychosis
The relationship between trauma and psychosis

... delusions of control  These ...


... This section of the chapter describesthe biological, genetic, and psychosocial factors-such as cognition, personality, and gender-that correlate with, or predispose to, depression. The discussion of genetic factors also incorporates the latest findings about bipolar disorder. Genes are implicated ev ...
Effect of Assertive Training Program on Social Interaction Anxiety
Effect of Assertive Training Program on Social Interaction Anxiety

... concerns from clinicians, researchers, and healthcare administrators, as these deficits are a major determinant of outcome for patients. Impaired social abilities in schizophrenia are thought to be partly attributable to specific aspects of symptomatology, such as negative symptoms (blunt affect, so ...
Psychological Disorders and Treatment - e
Psychological Disorders and Treatment - e

... diagnosing intellectual disabilities (an IQ score well below the average of 100). But if we use this definition, wouldn’t a person who has an extremely high IQ score also be classified as abnormal? What about Olympic athletes and world-renowned artists? Having an exceptional ability is infrequent, b ...
Overview of thyroid disease for psychiatrists
Overview of thyroid disease for psychiatrists

... •  Obesity  more  common  in  schizophrenia  but  the   drugs  appear  to  worsen  the  problem-­‐exact   mechanism  unclear   •  Large  inter-­‐individual  variaLon  in  weight  gain   with  the  drugs-­‐  some  very  large  indeed!   •  CATIE ...
The Nature and Specificity of Verbal Memory Interference in First
The Nature and Specificity of Verbal Memory Interference in First

... Although poorer cognitive flexibility and poorer verbal fluency reliably predicted less release from PI in FE patients, this finding was not unique to schizophrenia but rather characteristic of FE psychiatric illness in general. In contrast, poorer executive functioning was unrelated to build-up of ...
A psychobiographical analysis of Brian Douglas Wilson: Creativity
A psychobiographical analysis of Brian Douglas Wilson: Creativity

... them, they would threaten to kill him and his family (Ligerman & Leaf, 2004). Though these hallucinations are clear indication of some sort of psychiatric disorder, there is conflicting evidence regarding Wilson’s drug use relative to the onset and development of such symptoms. His autobiography cla ...
The Perceived Burden of Care and its Correlates in Schizophrenia
The Perceived Burden of Care and its Correlates in Schizophrenia

... in such countries can be beneficial for the enhancement of healthcare services provided to patients and their caregivers. There are few studies on the family members of schizophrenic patients in Turkey, and the existing ones included limited number of caregivers. Karancı (1995) studied Turkish careg ...
1 DEF PAPER ToM and IQ - Portal de revistas de la Universidad de
1 DEF PAPER ToM and IQ - Portal de revistas de la Universidad de

... proposed that the ToM deficits observed in schizophrenics are completely unrelated to psychopathology or intelligence, which would mean that poor ToM performance is a trait, and not a state, of the illness (Koelkebeck et al., 2010). What is clear is that the deficits in schizophrenics are much less ...
Physical and Sexual Assault History in Women With Serious Mental
Physical and Sexual Assault History in Women With Serious Mental

... A number of substantive and methodological factors help explain the variation in these rates. First, definitions of abuse were not consistent across studies. Second, despite extensive research documenting that detailed and behaviorally specific questions are necessary to elicit accurate abuse inform ...
NEUROPHYSIOLOGICAL RESPONSES AND BEHAVIOURAL INTENTIONS TO SCHIZOPHRENIA-ASSOCIATED COMMUNICATION ABNORMALITIES
NEUROPHYSIOLOGICAL RESPONSES AND BEHAVIOURAL INTENTIONS TO SCHIZOPHRENIA-ASSOCIATED COMMUNICATION ABNORMALITIES

... actually use the skills they possess, and other people’s reactions to someone with schizophrenia can affect those opportunities (Berge & Ranney, 2005). Neurocognitive deficits have also been linked to the manifestation of communication abnormalities (Bowie et al., 2011). It is possible that a compon ...
The psychotomimetic effects of PCP, LSD and MDMA
The psychotomimetic effects of PCP, LSD and MDMA

... PCP comprehensively induced symptoms resembling schizophrenia (52, 53, 56, 59, 60). Luby et al. (56) gave 9 HVs PCP in a subanaesthetic dose (0.1 mg/kg IV). All subjects experienced “body image changes” (impaired ability to distinguish between self and nonself stimuli, feelings of depersonalization, ...
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Mechanisms of schizophrenia



The underlying mechanisms of schizophrenia, a mental disorder characterized by a disintegration of the processes of thinking and of emotional responsiveness, are complex. A number of theories attempt to explain the link between altered brain function and schizophrenia, the most important of which are the dopamine hypothesis and the glutamate hypothesis. Note that these theories are separate from the causes of schizophrenia, which deal with actual starting points of the illness instead, e.g. genetic and environmental factors. The current theories attempt to explain how changes in brain functioning can contribute to symptoms of the disease.
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