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Thioredoxin Reductase 2 (Txnrd2) Regulates Mitochondrial Integrity
Thioredoxin Reductase 2 (Txnrd2) Regulates Mitochondrial Integrity

... the accumulation of damaged cellular components and that leads progressively to deterioration of biological functions.1 Recently, increased cellular production of reactive oxygen species (ROS) and decreased removal of oxidized proteins have been implicated in the aging process.2 During aging, ROS ge ...
Full text (PDF file)
Full text (PDF file)

... Activation of sublobule IX-b of the cerebellar vermis evokes hypotension, bradycardia and decrease of the phrenic nerve activity in the anesthetized animal. Cardiac performance during the isovolumic phases of systole and relaxation can be evaluated by dP/dtmax, Vpm, dP/dt/DP40 and τ, respectively. I ...
Recurrent ventricular arrhythmias and myocardial infarctions
Recurrent ventricular arrhythmias and myocardial infarctions

... myocardial ischemia associated with cocaine use and vasodilator therapy should be the mainstay of the treatment [8]. Standard management for ventricular arrhythmias, including lidocaine, is reasonable for persistent or recurrent ventricular arrhythmias. In our patient, ventricular arrhythmias on the ...
Longitudinally and circumferentially directed movements of the left
Longitudinally and circumferentially directed movements of the left

... (based on the AHA segmental) and for basal, mid and apical segments. The summation of segmental motion results in a complex pattern of ventricular twisting and longitudinal motion in the normal human heart which underlies systolic and diastolic function. As viewed from the apex, the entire LV initia ...
Exercise-Induced Left Ventricular Systolic Dysfunction in Women
Exercise-Induced Left Ventricular Systolic Dysfunction in Women

... heterozygote, in the parasternal short-axis view. Dark arrows indicate mid inferior myocardium, underlying the posteromedial view video clip online). papillary muscle (P), which demonstrates worse systolic function after exercise (see Video 1; ...
Understanding cardiac “echo” reports
Understanding cardiac “echo” reports

... Date of procedure. Before studying a TTE report, check its date (Table 1). Even recent studies can convey outdated impressions. Change is expected when a patient’s clinical status changes as a result of worsening disease or in response to treatment. Reason for the test. Explaining why echocardiograp ...
On-Pump and Off-Pump Coronary Artery Bypass Grafting
On-Pump and Off-Pump Coronary Artery Bypass Grafting

... the heart-lung machine or the pump), an artificial circulation system that does the work of the heart and the lungs. Pipes (cannulas) are placed in the heart to drain impure blood to the pump, where it is purified and pumped back into the patient. Thus, the heart can be safely stopped with specializ ...
Cardiac Pacemakers From the Patient`s Perspective
Cardiac Pacemakers From the Patient`s Perspective

... unit is slightly larger than a man’s wristwatch and contains a battery and computer circuits (Figure 1). The computer circuits perform the functions of monitoring the patient’s underlying heart rhythm and delivering an electrical signal to cause the heart to beat at the desired rate. Many pacemakers ...
Valvular Heart Disease
Valvular Heart Disease

... • Loud Opening S1 snap: heard at the apex when leaflets are still mobile – Due to the abrupt halt in leaflet motion in early diastole, after rapid initial rapid opening, due to fusion at the leaflet tips. – A shorter S2 to opening snap interval indicates more severe disease. ...
Print - Circulation
Print - Circulation

... 60 and 100 per minute. The rhythm was irregular as the degree of A-V block shifted from 2:1 to 4:1. There were no signs of congestive heart failure. The hemoglobin was 14.4 Gm., the hematocrit value 48 volumes per cent, and the white blood count 6,100. Urine analysis was negative except for a slight ...
Cardiovascular Disorders
Cardiovascular Disorders

... develop over time, resulting in further progression of mitral regurgitation (MR). Acute severe MR results in congestive heart failure symptoms without left ventricular dilatation. Conversely, chronic or progressively severe MR can lead to ventricular dilatation and dysfunction, neurohormonal activat ...
12-Development_of_Heart
12-Development_of_Heart

... CHANGES IN SINUS VENOSUS • Initially, sinus venosus opens into the atrium & is formed of 2 equal horns • Right horn: enlarges & becomes incorporated in the wall of right atrium • The valve between right horn & right atrium: its cranial part forms crista terminalis; its caudal part forms valves of I ...
Cardiac Resynchronization Therapy (CRT)
Cardiac Resynchronization Therapy (CRT)

... together. CRT makes sure the contractions are timed correctly. To do this, a biventricular pacemaker or ICD is connected to your heart. The device sends electrical impulses to the right and left ventricles. These impulses resynchronize the ventricles (make them contract together again). So, more blo ...
The Examination of the Heart Rate Recovery after Anaerobic
The Examination of the Heart Rate Recovery after Anaerobic

... H, YOKOYAMA H, TAKEDA H, INOUE M, KAMADA T, J Am Coll Cardiol, 24 (1994) 1529. — 17. LAMBERTS RP, LEMMINK KAPM, DURANDT JJ, LAMBERT MI, J Strength Cond Res, 18 (2004) 641. — 18. ...
CARDIAC PROPERTIES LECTURE – 4
CARDIAC PROPERTIES LECTURE – 4

Methods - Trials
Methods - Trials

... permanent AF; (2) serious left main coronary artery disease identified by coronary angiography; (3) heart failure [New York Heart Association (NYHA) III or IV]; (4) acute myocardial infarction in 3 months; (5) with surgical/interventional indications of valvular heart disease; (6) uncontrolled thyro ...
Heart Rate Variability: An Index of the Brain–Heart Interaction
Heart Rate Variability: An Index of the Brain–Heart Interaction

The Effects of Maternal Systemic Lupus Erythematosus on the
The Effects of Maternal Systemic Lupus Erythematosus on the

... As the chambers continue to form, valves that permit blood to flow from the atrial chambers to ventricular chambers must form. These valves, known as atrioventricular valves, also prevent the backflow of blood into the atrial compartments of the heart. In CHB, cardiac tissue formation is disrupted w ...
Atrial Septal Defect
Atrial Septal Defect

... • Primum ASDs account for 15% to 20% of ASDs and occur as part of the spectrum of atrioventricular canal defects. • They may occur as isolated defects (partial atrioventricular canal defect) or be accompanied by inlet VSDs (complete atrioventricular canal defect). • Partial canal defects typically h ...
Azimilide for the Treatment of Atrial Fibrillation, Atrial
Azimilide for the Treatment of Atrial Fibrillation, Atrial

... (PSVT). This study was designed to confirm efficacy of 125 mg daily azimilide. Methods and Results: The primary endpoint was ECG-documented recurrence of AF, AFL, or PSVT, followed for a maximum of 180 days. Four hundred eighty-two patients were enrolled in the United States and Canada (422 with AF ...


... selective antagonist of L-type Ca2+ channels, has completely abolished the positive inotropic activity induced by O. brevis extract indicating a direct effect of O. brevis extract on the Ca+2 channels of myocardial fibers. Neither, atropine as a muscarinic cholinergic antagonist, nor propronolol cou ...
File - Wk 1-2
File - Wk 1-2

Inglés  - SciELO México
Inglés - SciELO México

... explanation or citation of research.8 Likewise, Tanaka et al. in 20019 suggest a formula very well received today (208.75-0.7 * Age) apparently healthy adult subjects. In addition, there are more than 45 equations to determine the MHR according to different variables such as age and gender; but ther ...
CARDIOPULMONARY RESUSCITATION
CARDIOPULMONARY RESUSCITATION

... Airway Control and Ventilation • During low blood flow states such as CPR, oxygen delivery to the heart and brain is limited by blood flow rather than by arterial oxygen content. • Advanced airway placement in cardiac arrest should not delay initial CPR and defibrillation • Empirical use of 100% in ...
Brief Report Midaxillary lateral thoracotomy for closure of atrial
Brief Report Midaxillary lateral thoracotomy for closure of atrial

... alternatives claim that acute and late pain, and morbidity, are reduced.1–3 Thoracic surgeons have long considered the axillary thoracotomy as an optimal approach for pulmonary and mediastinal lesions.4-6 We claim no originality in describing our current approach, wishing only to highlight the possi ...
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Electrocardiography



Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.
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