Current indications for resynchronisation therapy.
... Long-term follow-up of MADIT-CRT patients will possibly allow us to determine whether in these mild HF patients, CRT-D also reduces mortality, which would be expected after about a 40% reduction the risk of HF events. ...
... Long-term follow-up of MADIT-CRT patients will possibly allow us to determine whether in these mild HF patients, CRT-D also reduces mortality, which would be expected after about a 40% reduction the risk of HF events. ...
Pathophysiology, risk stratification, and management
... Management of sudden cardiac death (SCD) is undergoing radical change in direction. It is becoming increasingly appreciated that besides depressed left ventricular systolic function and the conventional risk stratification tools, new markers for plaque vulnerability, enhanced thrombogenesis, specifi ...
... Management of sudden cardiac death (SCD) is undergoing radical change in direction. It is becoming increasingly appreciated that besides depressed left ventricular systolic function and the conventional risk stratification tools, new markers for plaque vulnerability, enhanced thrombogenesis, specifi ...
Phenotyping transgenic embryonic murine hearts using optical
... the body. The excised heart was pinned to silicone between two platinum plates in a pacing chamber filled with oxygenated saline solution. The heart was pinned with the ventral surface facing up, which allowed for four-chambered en face OCT images. The hearts were paced at 1 Hz and imaged with a gat ...
... the body. The excised heart was pinned to silicone between two platinum plates in a pacing chamber filled with oxygenated saline solution. The heart was pinned with the ventral surface facing up, which allowed for four-chambered en face OCT images. The hearts were paced at 1 Hz and imaged with a gat ...
(B-type Natriuretic Peptide (BNP Testing)
... treatment can be initiated. This test is also used to predict the long-term risk of cardiac events or death across the spectrum of acute coronary syndromes when measured in the first few days after an acute coronary event. For the purposes of this policy, either total or N-terminal assays are accept ...
... treatment can be initiated. This test is also used to predict the long-term risk of cardiac events or death across the spectrum of acute coronary syndromes when measured in the first few days after an acute coronary event. For the purposes of this policy, either total or N-terminal assays are accept ...
Developmental and Physiological Aspects of the Chicken Embryonic
... for the heart rate to stay normal and constant (about 100 beats per minute), the embryos must be maintained at 37°C. This can be easily controlled by having a steady supply of warm chick saline. To ensure that it is warm enough, we keep about six 200 ml bottles of the chick saline in a 45°C water ba ...
... for the heart rate to stay normal and constant (about 100 beats per minute), the embryos must be maintained at 37°C. This can be easily controlled by having a steady supply of warm chick saline. To ensure that it is warm enough, we keep about six 200 ml bottles of the chick saline in a 45°C water ba ...
Increased Myocardial Oxygen Consumption and Contractile State
... characterized by determining the maximum observed contractile element velocity (max V) at the lowest common level of wall stress in any experiment (21). In each of eight dogs, from two to four different levels of heart rate were studied, ranging between 98 and 202 beats/min. The sequence of heart ra ...
... characterized by determining the maximum observed contractile element velocity (max V) at the lowest common level of wall stress in any experiment (21). In each of eight dogs, from two to four different levels of heart rate were studied, ranging between 98 and 202 beats/min. The sequence of heart ra ...
Mechanism of Ventricular Fibrillation in Hypothermia
... that the antifibrillary activity of norepinephrine, mephentermine, and inethoxamine was related to an increase in conduction velocity. To obtain more definitive evidence on this point, myocardial conduction time, refractory period, and QES duration were measured in 10 dogs in which either norepineph ...
... that the antifibrillary activity of norepinephrine, mephentermine, and inethoxamine was related to an increase in conduction velocity. To obtain more definitive evidence on this point, myocardial conduction time, refractory period, and QES duration were measured in 10 dogs in which either norepineph ...
Complexity of physiological responses decreases in high
... for performances of the same piece in low-stress and highstress conditions. We set out to dynamically examine stress signatures caused by (i) varying physical and cognitive demands within the musical piece (identical across performances) and (ii) audience-induced anxiety (different across performanc ...
... for performances of the same piece in low-stress and highstress conditions. We set out to dynamically examine stress signatures caused by (i) varying physical and cognitive demands within the musical piece (identical across performances) and (ii) audience-induced anxiety (different across performanc ...
Development of the Pacemaker Tissues of the Heart
... load of the atrium, allowing the SAN to activate the atrium through narrow superior and inferior SAN exit pathways.29 Classically, the SAN has been delineated using histological properties associated with nodal myocytes, including pale glycogen rich cells, poorly developed myofibrils, connective tis ...
... load of the atrium, allowing the SAN to activate the atrium through narrow superior and inferior SAN exit pathways.29 Classically, the SAN has been delineated using histological properties associated with nodal myocytes, including pale glycogen rich cells, poorly developed myofibrils, connective tis ...
CARDIAC POWER OUTPUT, ITS ROLE IN DEFINING HEART
... left ventricular assist device (HeartMate II) as an end of life care support (destination therapy) or until an orthotopic heart became available to transplant (bridge to transplant). The remaining 5 survivors had the Syncardia temporary Total Artificial Heart (TAH-t) as a temporary support device fo ...
... left ventricular assist device (HeartMate II) as an end of life care support (destination therapy) or until an orthotopic heart became available to transplant (bridge to transplant). The remaining 5 survivors had the Syncardia temporary Total Artificial Heart (TAH-t) as a temporary support device fo ...
How to best to counteract the enemies? By blocking neurohormonal activation
... of beta-1 AR stimulation can be opposed by stimulation of beta-2 AR, whereas stimulation of alpha-1 AR causes myocyte hypertrophy and may exert an antiapoptotic action as well[16,17]. The net balance between proapoptotic and antiapoptotic actions associated with adrenergic up-regulation and desensit ...
... of beta-1 AR stimulation can be opposed by stimulation of beta-2 AR, whereas stimulation of alpha-1 AR causes myocyte hypertrophy and may exert an antiapoptotic action as well[16,17]. The net balance between proapoptotic and antiapoptotic actions associated with adrenergic up-regulation and desensit ...
Full PDF - IOSR Journal of Pharmacy
... The results on cardiotonic activity of paraoxon induced and normal parotoid gland secretions (without induction) are presented in Tables 1&2, Fig 1&2 and Graphs.1&2. The results indicated that the parotoid exudates on isolated perfused frog hearts elicited dose dependent effect. There was an increas ...
... The results on cardiotonic activity of paraoxon induced and normal parotoid gland secretions (without induction) are presented in Tables 1&2, Fig 1&2 and Graphs.1&2. The results indicated that the parotoid exudates on isolated perfused frog hearts elicited dose dependent effect. There was an increas ...
Free Full Text - Hellenic Society of Nuclear Medicine
... activity that could result in false positive defects on myocardial perfusion stress images (Figure 1a, b) [15]. However, truncation at the apex of the heart was observed. In detail, truncation of activity of apical portion of the heart from frame 45-60 (detector 1) and frames 1-5 (detector 2) was no ...
... activity that could result in false positive defects on myocardial perfusion stress images (Figure 1a, b) [15]. However, truncation at the apex of the heart was observed. In detail, truncation of activity of apical portion of the heart from frame 45-60 (detector 1) and frames 1-5 (detector 2) was no ...
as PDF - Unit Guide
... maintenance of homeostasis • Identify specific structural features of organ systems and explain how they underlie essential functions • Use equations describing physical, chemical and electrical principles to predict and interpret important physiological processes • Identify situations in which the ...
... maintenance of homeostasis • Identify specific structural features of organ systems and explain how they underlie essential functions • Use equations describing physical, chemical and electrical principles to predict and interpret important physiological processes • Identify situations in which the ...
Diagnosis and Treatment of Constrictive Pericarditis
... range of possible pathologies affecting the pericardium (e.g., idiopathic, postsurgical/trauma, infectious, autoimmune disorders, irradiation, uremia, neoplastic, sarcoid, methysergide therapy). The end result is that the heart’s diastolic function (i.e. lusitropism) is limited by constriction relat ...
... range of possible pathologies affecting the pericardium (e.g., idiopathic, postsurgical/trauma, infectious, autoimmune disorders, irradiation, uremia, neoplastic, sarcoid, methysergide therapy). The end result is that the heart’s diastolic function (i.e. lusitropism) is limited by constriction relat ...
Anaesthetist`s evaluation of a child with a heart murmur
... and sometimes during adolescence. It is caused by blood flow in the mammary vessels and is heard over the breast. There is a distinct gap between S1 and the onset of the murmur because of delayed arrival of blood flow, and it may extend into diastole. Again, PDA or AVM must be excluded.2 ...
... and sometimes during adolescence. It is caused by blood flow in the mammary vessels and is heard over the breast. There is a distinct gap between S1 and the onset of the murmur because of delayed arrival of blood flow, and it may extend into diastole. Again, PDA or AVM must be excluded.2 ...
Atrioventricular node fetal dispersion and His bundle
... Interpretation of our results. In our series we have observed these two abnormalities very frequently and in advanced adulthood (Tables 2 and 3). We think the explanation for this discrepancy in comparison with the reports of James et al. and Bharari et al. need not lie in the number of sections exa ...
... Interpretation of our results. In our series we have observed these two abnormalities very frequently and in advanced adulthood (Tables 2 and 3). We think the explanation for this discrepancy in comparison with the reports of James et al. and Bharari et al. need not lie in the number of sections exa ...
The Contribution of Doppler Echocardiography to the Assessment of
... of heart failure patients with a narrow QRS and in 64% of cases with a wide QRS. Strain rate and tissue tracking are two new echocardiographic techniques, which are based on LV long axis function assessment and have also been used to estimate intraventricular dyssynchrony. These methods are based on ...
... of heart failure patients with a narrow QRS and in 64% of cases with a wide QRS. Strain rate and tissue tracking are two new echocardiographic techniques, which are based on LV long axis function assessment and have also been used to estimate intraventricular dyssynchrony. These methods are based on ...
APPLICATIONS OF IMPLANTABLE MEDICAL SENSORS FOR HEART FALIURE: A REVIEW
... pacemakers (PPM), implantable cardioverter-defibrillators (ICD), or cardiac resynchronization therapy devices that have been placed for other indications.Or, they can be specially designed implantable hemodynamic sensors and monitors that can measure such parameters as intracardiac pressures. Remote ...
... pacemakers (PPM), implantable cardioverter-defibrillators (ICD), or cardiac resynchronization therapy devices that have been placed for other indications.Or, they can be specially designed implantable hemodynamic sensors and monitors that can measure such parameters as intracardiac pressures. Remote ...
Clinicopathologic characteristics of elderly patients with
... past history suggestive of common cold related to myocarditis before the onset of illness in the remaining 10 patients. On admission, Patient 6 showed positive C-reactive protein and mild pericardial effusion on the echocardiogram, but this disappeared a few weeks later. Virologic tests performed in ...
... past history suggestive of common cold related to myocarditis before the onset of illness in the remaining 10 patients. On admission, Patient 6 showed positive C-reactive protein and mild pericardial effusion on the echocardiogram, but this disappeared a few weeks later. Virologic tests performed in ...
Dallas Cardiovascular Specialists
... leaks, the doctor may also hear a murmur. The doctor may ask you to stand, sit, lie down, or squat during your exam, so he or she can better hear the heart sounds. An echocardiogram passes sound waves through the heart to create an image. It is the best test to diagnose mitral valve prolapse. The im ...
... leaks, the doctor may also hear a murmur. The doctor may ask you to stand, sit, lie down, or squat during your exam, so he or she can better hear the heart sounds. An echocardiogram passes sound waves through the heart to create an image. It is the best test to diagnose mitral valve prolapse. The im ...
Pediatric Left Atrial Myxoma: Surgical Excision and Mitral Valve Plasty
... the heart, and may result in compression of cardiac structures, valvular insufficiency, outflow tract obstruction, coronary emboli, and occasionally sudden death. Although mitral insufficiency is common in cases with left ...
... the heart, and may result in compression of cardiac structures, valvular insufficiency, outflow tract obstruction, coronary emboli, and occasionally sudden death. Although mitral insufficiency is common in cases with left ...
Rhythm Control Versus Rate Control and€Clinical Outcomes in
... Amit Noheria, MBBS, SM,a Peter Shrader, MA,b Jonathan P. Piccini, MD, MHS,b Gregg C. Fonarow, MD,c ...
... Amit Noheria, MBBS, SM,a Peter Shrader, MA,b Jonathan P. Piccini, MD, MHS,b Gregg C. Fonarow, MD,c ...
Imaging cardiac activation sequence during ventricular tachycardia
... electrode-pairs (inter-electrode distance of 500 m), each separated by 2.5 mm (28, 29), and each RV electrode contains eight bipolar electrode-pairs with an inter-electrode distance of 500 m (30). There were no significant changes in heart rate or mean arterial blood pressure after electrode inser ...
... electrode-pairs (inter-electrode distance of 500 m), each separated by 2.5 mm (28, 29), and each RV electrode contains eight bipolar electrode-pairs with an inter-electrode distance of 500 m (30). There were no significant changes in heart rate or mean arterial blood pressure after electrode inser ...
Distinguishing myocardial infarction type 1 and type 2.
... whether the presence or likely presence of CAD should be required for the diagnosis of type 2 MI. The task force split over this point but the majority opinion was that CAD was not necessary for a patient to have ischemic myocardial necrosis. For example, the young person with many hours of rapid ta ...
... whether the presence or likely presence of CAD should be required for the diagnosis of type 2 MI. The task force split over this point but the majority opinion was that CAD was not necessary for a patient to have ischemic myocardial necrosis. For example, the young person with many hours of rapid ta ...
Electrocardiography
Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.