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Hypopituitarism

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Interaction between the 5-HT system and the basal ganglia
Interaction between the 5-HT system and the basal ganglia

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... is not tightly regulated as it is under control of thyroid releasing hormone (TRH) and feedback from fluctuating systemic thyroid hormones which are subject to binding issues, iodine effects, and many other factors. ...
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Hypothalamus



The hypothalamus (from Greek ὑπό, ""under"" and θάλαμος, ""room, chamber"") is a portion of the brain that contains a number of small nuclei with a variety of functions. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis).The hypothalamus is located below the thalamus, just above the brainstem and is part of the limbic system. In the terminology of neuroanatomy, it forms the ventral part of the diencephalon. All vertebrate brains contain a hypothalamus. In humans, it is the size of an almond.The hypothalamus is responsible for certain metabolic processes and other activities of the autonomic nervous system. It synthesizes and secretes certain neurohormones, often called releasing hormones or hypothalamic hormones, and these in turn stimulate or inhibit the secretion of pituitary hormones.The hypothalamus controls body temperature, hunger, important aspects of parenting and attachment behaviors, thirst, fatigue, sleep, and circadian rhythms.
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