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... Extrinsic alveolitis • Caused by deposition if insoluble immune complexes in the lung tissue. The complexes are formed from exogenous antigen and excess if antibodies of IgG class. • 6-8 hours after exposition the patient suffers from dry cough, dyspnea, increased body ...
notes
notes

... Clonal Selection theory • For Immune system response to infection • Based on the concept of cloning and affinity maturation • B and T lymphocytes are selected to destroy the antigens invading the body • When an antigen enters the body, the B cells that best bind with the antigens proliferate by clo ...
Immunology Ch 1 1-22 [4-20
Immunology Ch 1 1-22 [4-20

... Lymphocytes – cells produce receptors specific for diverse antigens, mediate adaptive immunity -distinguished by different surface markers Clusters of Differentiation -B cells capable of producing antibodies and mediate humoral immunity; express membrane forms of antibodies, to which antigens bind a ...
T Cell Development in the Thymus David Straus
T Cell Development in the Thymus David Straus

Pathology – Lecture 17: Immunohemolytic Anemia 2/25/13
Pathology – Lecture 17: Immunohemolytic Anemia 2/25/13

... o The pt’s red cells are mixed w/ sera containing antibodies that are specific for human Ig or complement (anti-human globulin, AHG) o If agglutination (clumping) occurs = positive test  Indirect Coombs antiglobulin test o The pt’s serum is tested for its ability to agglutinate commercially availab ...
Immunopathology
Immunopathology

... aggregate of epithelioid cells and surrounded by lymphocytes. The granuloma in the center shows several multinucleate giant cells. ( Dr. Trace Worrell) (From Robbins Basic Pathology ,2003) Slide 7.17 ...
Cardiovascular System
Cardiovascular System

... i. ___________ in hemoglobin is binding site for CO2 and O2 ii. Each hemoglobin is composed of 4 protein subunits, each with one __________ group located in the center 3. RBCs have no _________________ and lack most cellular organelles a. RBCs can’t reproduce, only live for ____________________days ...
Mechanisms of neutrophil accumulation in obstructive airways disease
Mechanisms of neutrophil accumulation in obstructive airways disease

... disease of older people is poorly understood. It is likely to be important but also different to younger people because of life-long exposures to particulates such as cigarette smoke or other immune stimuli such as infections. Neutrophils are a key cell present in the airways playing an important ro ...
5a Innate Immunity
5a Innate Immunity

... Antimicrobial Proteins: Complement  What they are • About 20 blood proteins that circulate in an inactive form ...
Lecture #14 Bio3124 - University of Ottawa
Lecture #14 Bio3124 - University of Ottawa

... • soluble, heat-labile, proteins • usually released into the surroundings as bacterial pathogen grows • most exotoxin producers are gram-positive • often travel from site of infection to other tissues or ...
Bacteria, Virus and Immune System Objectives
Bacteria, Virus and Immune System Objectives

... 4. Describe, in detail, the relationship between an antigen and antibody. 5. Explain why you only get chickenpox once (most people) but can get the flu almost every year. 6. Describe the roles of each type of white blood cell. (macrophages, cytotoxic tcells, helper t cells, plasma cells, phagocytes) ...
Aptamer-targeted inhibition of mTOR in T cells enhances antitumor
Aptamer-targeted inhibition of mTOR in T cells enhances antitumor

Vaccine Shows Response in Some Leukemia Patients Drug`s
Vaccine Shows Response in Some Leukemia Patients Drug`s

Immune system
Immune system

... immune deficiency syndrome (AIDS) that is caused by the retrovirus HIV. In contrast, autoimmune diseases result from a hyperactive immune system attacking normal tissues as if they were foreign organisms. Common autoimmune diseases include rheumatoid arthritis, diabetes mellitus type 1 and lupus ery ...
Bibliographic Vision on Plant Immunity Primary Immune System
Bibliographic Vision on Plant Immunity Primary Immune System

... present as a second phase at animals and humans. It is likely to have a systemic immunity at some plants, which we yet know little. The PAMPs = Pathogen-Associated Molecular Patterns, exists on the surface of leafs which, in this case of bacteria is microbial. Immunity is triggered even by this asso ...
Immune System - Bakersfield College
Immune System - Bakersfield College

... • Engulf foreign cells or molecules/debris from dead cells • Alert adaptive defense system ...
Lymph Nodes
Lymph Nodes

... – Anything body perceives as foreign • Bacteria and bacterial toxins, viruses, mismatched RBCs, cancer cells ...
Document
Document

... Mechanisms proposed for development of autoimmunity 5. Mediators ...
Export To Word
Export To Word

... This interactive virtual manipulative will help the students in understanding how the wide variety of cell types work together to sustain the life of an organism. In this animation students will observe the complex biochemical process of how cells respond to their environment and communicate with ea ...
and t-lymphocyte immune deficiencies
and t-lymphocyte immune deficiencies

...  Genetic deficiencies of the classical complement pathway (C1, C2 and C4) are associated with a high prevalence of autoimmune disease, particularly severe systemic lupus erythematosus (SLE)  Mannose-binding lectin deficiency is very common (5% of the population).  Individuals with complete mannos ...
Diapositiva 1
Diapositiva 1

... • In mice, they demonstrate that cyclophosphamide alters the composition of small intestine microbiota and induces the translocation of selected species of Gram+ bacteria into secondary lymphoid organs. • There, these bacteria stimulate the generation of “pathogenic” T helper 17 cells (pTh17) and me ...
TATA Molecular Immunology
TATA Molecular Immunology

Use of Bacteria in Antibody Production - BLI-Research-Synbio
Use of Bacteria in Antibody Production - BLI-Research-Synbio

... • There are many diseases in the world caused by pathogens that devastate many people each year, causing pain, financial loss, and death ...
Cancer Prevention - Steven Chaney 2014
Cancer Prevention - Steven Chaney 2014

... Antioxidants -- because immune cells use free radicals to kill cancer cells ( and viruses, bacteria ) • The cells have to be protected from the free radicals. Immune cells contain phagosomes that engulf the cancer cell and then create free radicals to kill it. ...
Scoring Guidelines - AP Central
Scoring Guidelines - AP Central

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Immune system



The immune system is a system of many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. In many species, the immune system can be classified into subsystems, such as the innate immune system versus the adaptive immune system, or humoral immunity versus cell-mediated immunity.Pathogens can rapidly evolve and adapt, and thereby avoid detection and neutralization by the immune system; however, multiple defense mechanisms have also evolved to recognize and neutralize pathogens. Even simple unicellular organisms such as bacteria possess a rudimentary immune system, in the form of enzymes that protect against bacteriophage infections. Other basic immune mechanisms evolved in ancient eukaryotes and remain in their modern descendants, such as plants and insects. These mechanisms include phagocytosis, antimicrobial peptides called defensins, and the complement system. Jawed vertebrates, including humans, have even more sophisticated defense mechanisms, including the ability to adapt over time to recognize specific pathogens more efficiently. Adaptive (or acquired) immunity creates immunological memory after an initial response to a specific pathogen, leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination.Disorders of the immune system can result in autoimmune diseases, inflammatory diseases and cancer.Immunodeficiency occurs when the immune system is less active than normal, resulting in recurring and life-threatening infections. In humans, immunodeficiency can either be the result of a genetic disease such as severe combined immunodeficiency, acquired conditions such as HIV/AIDS, or the use of immunosuppressive medication. In contrast, autoimmunity results from a hyperactive immune system attacking normal tissues as if they were foreign organisms. Common autoimmune diseases include Hashimoto's thyroiditis, rheumatoid arthritis, diabetes mellitus type 1, and systemic lupus erythematosus. Immunology covers the study of all aspects of the immune system.
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