投影片 1
... Su CC, et al. 2007 Phosphatidylinositol 3-Kinase/Akt activation by integrin-tumor matrix interaction suppresses Fas-mediated apoptosis in T cells. J Immunol 179:4589-4597. ...
... Su CC, et al. 2007 Phosphatidylinositol 3-Kinase/Akt activation by integrin-tumor matrix interaction suppresses Fas-mediated apoptosis in T cells. J Immunol 179:4589-4597. ...
Immunology of Transplantation & Malignancy
... cells or by removal of a primary tumor. Also, immunity can be transferred from an animal, in which a tumor has regressed, to a naive animal by injection of lymphocytes (T cells). All components of the immune system (nonspecific and specific; humoral and cellular) can affect the growth and progressio ...
... cells or by removal of a primary tumor. Also, immunity can be transferred from an animal, in which a tumor has regressed, to a naive animal by injection of lymphocytes (T cells). All components of the immune system (nonspecific and specific; humoral and cellular) can affect the growth and progressio ...
... interdigitating cytological, biochemical, and immunological components serve to return to a physiological baseline of optimal organ function. Processes which constitute inflammation form an intricate functional network, in which almost every single constituent influences the activities of other cons ...
X-linked hyper IgM syndrome = CD40 ligand deficiency
... •Produce only very low levels of other classes of antibody because of problems with Ig class switching. •Patients are highly susceptible to infection with extracellular pathogens •At least six different gene mutations cause hyper IgM syndrome •Most common form: X-linked hyper IgM syndrome = CD40 lig ...
... •Produce only very low levels of other classes of antibody because of problems with Ig class switching. •Patients are highly susceptible to infection with extracellular pathogens •At least six different gene mutations cause hyper IgM syndrome •Most common form: X-linked hyper IgM syndrome = CD40 lig ...
Supplementary material
... Epithelial cells and dendritic cells are the two cell types in the present model which can directly respond to bacteria. Epithelial cells lining the inside of the lungs are the first ones to come across the pathogens. Hence their activation state directly depends on the presence or absence of the ba ...
... Epithelial cells and dendritic cells are the two cell types in the present model which can directly respond to bacteria. Epithelial cells lining the inside of the lungs are the first ones to come across the pathogens. Hence their activation state directly depends on the presence or absence of the ba ...
Viruses
... What are viruses? • ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic. ...
... What are viruses? • ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic. ...
Section 2: Enzymes and Digestion
... Large pieces of food are broken down into smaller pieces by processes such as chewing and the churning of food in the stomach. This makes it possible to not only absorb food but to increase its surface area, thus making it easier for chemical absorption. ...
... Large pieces of food are broken down into smaller pieces by processes such as chewing and the churning of food in the stomach. This makes it possible to not only absorb food but to increase its surface area, thus making it easier for chemical absorption. ...
Blood clot
... a) phagocytosis by the neutrophils and macrophages (professional phagocytes) b) eosinophils - phagocytize the antigen-antibody complexes - kill parasites (attach to the parasite and attack its cell membrane) c) action of some types of lymphocytes: • NK (natural killer) and LAK (lymphokine activated ...
... a) phagocytosis by the neutrophils and macrophages (professional phagocytes) b) eosinophils - phagocytize the antigen-antibody complexes - kill parasites (attach to the parasite and attack its cell membrane) c) action of some types of lymphocytes: • NK (natural killer) and LAK (lymphokine activated ...
Pathogenesis of Autoimmune Diseases: A Short
... organism called as autoimmunity. 1 Autoimmunity is the mechanism where an organism fails to recognize its Autoimmunity is characterized by the reaction of cells (auto reactive T-lymphocytes) or products (autoantibodies) of own constituent parts (down to the submolecular levels) the immune system aga ...
... organism called as autoimmunity. 1 Autoimmunity is the mechanism where an organism fails to recognize its Autoimmunity is characterized by the reaction of cells (auto reactive T-lymphocytes) or products (autoantibodies) of own constituent parts (down to the submolecular levels) the immune system aga ...
immunology-introduction
... activation, respectively. This DAG structure has certain advantages in annotation of things like T cell proliferation assays. T cell and B cell activation are defined in the GO to include any type of activation of those cell types, not just activation through the TCR or BCR, and included implicitl ...
... activation, respectively. This DAG structure has certain advantages in annotation of things like T cell proliferation assays. T cell and B cell activation are defined in the GO to include any type of activation of those cell types, not just activation through the TCR or BCR, and included implicitl ...
Transplantation Immunology
... with the marrow cells, these mature Tcells recognize the tissues of the recipient as ...
... with the marrow cells, these mature Tcells recognize the tissues of the recipient as ...
the attached hematopoiteic cascade
... IL-6: Provokes a broad range of cellular and physiological responses and plays a role in inflammation and hematopoiesis ...
... IL-6: Provokes a broad range of cellular and physiological responses and plays a role in inflammation and hematopoiesis ...
Cells and Tissues PPT
... concenration but is used when the substance cannot move across the plasma (cell) membrane ...
... concenration but is used when the substance cannot move across the plasma (cell) membrane ...
FactSHEET DNCB What is DNCB?
... DNCB became widely used by researchers for this purpose. The test method involved applying DNCB to the skin; if DNCB failed to cause a delayed-type hypersensitivity reaction, the cell-mediated immune system likely was not functioning properly. Researchers also observed that DNCB would actually stimu ...
... DNCB became widely used by researchers for this purpose. The test method involved applying DNCB to the skin; if DNCB failed to cause a delayed-type hypersensitivity reaction, the cell-mediated immune system likely was not functioning properly. Researchers also observed that DNCB would actually stimu ...
CellFactoryChemE355 - University of Washington
... •Transcription of all detectable genes •Production of all detectable proteins •Measurement of all major fluxes •Measurement of 100s of metabolites Involves a basic assumption, that all cells are roughly in the same physiological state ...
... •Transcription of all detectable genes •Production of all detectable proteins •Measurement of all major fluxes •Measurement of 100s of metabolites Involves a basic assumption, that all cells are roughly in the same physiological state ...
Syllabus
... There is a short reader for this class containing 6 different discussion articles covering various topics. Attendance in section is required for discussion and poster presentation meetings. The discussion articles are to be read prior to section. Participation in these discussions will be part of yo ...
... There is a short reader for this class containing 6 different discussion articles covering various topics. Attendance in section is required for discussion and poster presentation meetings. The discussion articles are to be read prior to section. Participation in these discussions will be part of yo ...
Autoimmune Diseases
... result in presentation of self Ags for which there is no tolerance • In several diseases, there are host cells that exhibit class II molecules on their surfaces after inflammatory response • Such cells may function as Ag presenting cells for their own cellular proteins ...
... result in presentation of self Ags for which there is no tolerance • In several diseases, there are host cells that exhibit class II molecules on their surfaces after inflammatory response • Such cells may function as Ag presenting cells for their own cellular proteins ...
Antigen Binding and Idiotype Analysis of Antibodies Obtained
... cells along with one of the three dominant L chain genes from PC-binding antibodies (Table 1, cell lines 1-3). As expected, the antibodies produced by all combinations of electroporated H and L chain genes expressed K, #~-allotype, and VHI-Id markers. The homologous T15 cell line, which resulted fro ...
... cells along with one of the three dominant L chain genes from PC-binding antibodies (Table 1, cell lines 1-3). As expected, the antibodies produced by all combinations of electroporated H and L chain genes expressed K, #~-allotype, and VHI-Id markers. The homologous T15 cell line, which resulted fro ...
Structured illumination microscopy reveals novel insights into
... actomyosin arcs are bonafide structures in both Jurkat cells and primary mouse CD4/8+ T cells. A popular model suggests that the branched actin network comprising the dSMAC, which is created by Arp2/3-dependent nucleation, is converted into the concentric arcs by debranching and crosslinking. In con ...
... actomyosin arcs are bonafide structures in both Jurkat cells and primary mouse CD4/8+ T cells. A popular model suggests that the branched actin network comprising the dSMAC, which is created by Arp2/3-dependent nucleation, is converted into the concentric arcs by debranching and crosslinking. In con ...
Microsoft Word - Supplementaryl Material Antikörper tabelle
... was taken from M. quadriceps femoris, M. biceps femoris, M. triceps surae, M. biceps brachii and M. triceps brachii. Tissue samples were harvested, minced and centrifuged at 1000 x g for 5 min. Cells were digested with 0.2 % pronase (Roche) for 1 hour at 37 °C under constant agitation. After digesti ...
... was taken from M. quadriceps femoris, M. biceps femoris, M. triceps surae, M. biceps brachii and M. triceps brachii. Tissue samples were harvested, minced and centrifuged at 1000 x g for 5 min. Cells were digested with 0.2 % pronase (Roche) for 1 hour at 37 °C under constant agitation. After digesti ...
Virus CD8+ T Cell Response to Influenza SEP
... antigenic consequences. This exerts substantial selective pressure to promote new strains of flu (5). Influenza spreads when mucous droplets containing virus particles are aerosolized through sneezing or coughing of the infected individual and inhaled by a new host, exposing the epithelial cells of ...
... antigenic consequences. This exerts substantial selective pressure to promote new strains of flu (5). Influenza spreads when mucous droplets containing virus particles are aerosolized through sneezing or coughing of the infected individual and inhaled by a new host, exposing the epithelial cells of ...
Immunity Against Fungal Infections
... linked to cystic fibrosis.37 As an indication of the complexity of these issues, Th2-associated antibody responses can also partially increase the Th1 cell response.38 Th17 cells act principally at mucosal surfaces, including the lungs, where these cells play important roles in protective antifungal ...
... linked to cystic fibrosis.37 As an indication of the complexity of these issues, Th2-associated antibody responses can also partially increase the Th1 cell response.38 Th17 cells act principally at mucosal surfaces, including the lungs, where these cells play important roles in protective antifungal ...
Polyclonal B cell response
Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.