Effects of Microcin B17 on Microcin Bl7-immune Cells
... ensuring that producer strains are protected against the killing effect of the anti-bacterial agent. Microcin B17 kills sensitive E. coli K12 cells. Its primary effect is the inhibition of DNA synthesis. DNA degradation follows and expression of the SOS repair system is induced. This induction depen ...
... ensuring that producer strains are protected against the killing effect of the anti-bacterial agent. Microcin B17 kills sensitive E. coli K12 cells. Its primary effect is the inhibition of DNA synthesis. DNA degradation follows and expression of the SOS repair system is induced. This induction depen ...
Immunomodulatory Activity of Septilin, a Polyherbal
... Determination of T-lymphocyte function (Lakadawala et al., 1988; Borell et al., 1977; Florentin et al., 1978). To determine the effect of the drugs on cell mediated immunity, the delayed hypersensitivity to oxazolone was assessed. On day 20 of drug therapy, the mice were shaved from the mid-abdomina ...
... Determination of T-lymphocyte function (Lakadawala et al., 1988; Borell et al., 1977; Florentin et al., 1978). To determine the effect of the drugs on cell mediated immunity, the delayed hypersensitivity to oxazolone was assessed. On day 20 of drug therapy, the mice were shaved from the mid-abdomina ...
Local immunity of the respiratory mucosal system in chickens and
... has been corroborated by numerous scientific studies. The nasal mucosa, with structured clusters of lymphoid tissue (NALT – nasal-associated lymphoid tissue) is the first to come into contact with microorganisms which contaminate inhaled air. Lymphoid nodules, made up of B cells with frequently deve ...
... has been corroborated by numerous scientific studies. The nasal mucosa, with structured clusters of lymphoid tissue (NALT – nasal-associated lymphoid tissue) is the first to come into contact with microorganisms which contaminate inhaled air. Lymphoid nodules, made up of B cells with frequently deve ...
tumor
... The person with AIDS can develop other health problems. • The immune system is damaged. Copyright © 2012 by Mosby, an imprint of Elsevier Inc. All rights reserved. ...
... The person with AIDS can develop other health problems. • The immune system is damaged. Copyright © 2012 by Mosby, an imprint of Elsevier Inc. All rights reserved. ...
3. Cell membranes
... – Solutes able to freely cross the membrane do not affect tonicity because they will always be in equal concentrations on both sides of the membrane. http://www.youtube.com/watch?v=6MWl3DCa2uM ...
... – Solutes able to freely cross the membrane do not affect tonicity because they will always be in equal concentrations on both sides of the membrane. http://www.youtube.com/watch?v=6MWl3DCa2uM ...
An Introduction to Biology - Emory
... Is the world of living things in disorder without being organized? As it isn’t, any living things do seem to have hierarchical organization. Any living thing falls under a hierarchical level. The representation of level in order to have easier picture of the sense of hierarchy is called hierarchy of ...
... Is the world of living things in disorder without being organized? As it isn’t, any living things do seem to have hierarchical organization. Any living thing falls under a hierarchical level. The representation of level in order to have easier picture of the sense of hierarchy is called hierarchy of ...
Increased Generation of HIV-1 gp120-Reactive Encoding the Chemokine CCL3
... chemokine CCL3 which is a ligand of the chemokine receptors CCR1 and CCR5 and which production is inducible in numerous cell types including cells of the immune system, epithelial cells, and fibroblasts [31,32]. In mouse models, CCL3 has been shown to recruit Langerhans cells, dendritic cells (DCs), ...
... chemokine CCL3 which is a ligand of the chemokine receptors CCR1 and CCR5 and which production is inducible in numerous cell types including cells of the immune system, epithelial cells, and fibroblasts [31,32]. In mouse models, CCL3 has been shown to recruit Langerhans cells, dendritic cells (DCs), ...
Current subjects of research:
... The objective is to elucidate the antiviral and immune regulatory properties of CD4 Tcells from patients who do exceptionally well clinically following HIV infection (so called controllers) or following multiple exposures to HIV (so called highly-exposed persistently seronegative individuals {HEPS}) ...
... The objective is to elucidate the antiviral and immune regulatory properties of CD4 Tcells from patients who do exceptionally well clinically following HIV infection (so called controllers) or following multiple exposures to HIV (so called highly-exposed persistently seronegative individuals {HEPS}) ...
curriculum vitae - University of Michigan
... Status: Accepted Research Description: Grant proposal for extension of current DOE grant above. Further characterization of the RabA4blabeled membrane compartments in Arabidopsis and identification of molecular components involved in proper positioning of these membranes in the tips of growing root ...
... Status: Accepted Research Description: Grant proposal for extension of current DOE grant above. Further characterization of the RabA4blabeled membrane compartments in Arabidopsis and identification of molecular components involved in proper positioning of these membranes in the tips of growing root ...
CURRICULUM VITAE - University of Michigan
... Status: Accepted Research Description: Grant proposal for extension of current DOE grant above. Further characterization of the RabA4blabeled membrane compartments in Arabidopsis and identification of molecular components involved in proper positioning of these membranes in the tips of growing root ...
... Status: Accepted Research Description: Grant proposal for extension of current DOE grant above. Further characterization of the RabA4blabeled membrane compartments in Arabidopsis and identification of molecular components involved in proper positioning of these membranes in the tips of growing root ...
Müller Cell - American Diabetes Association
... induces Müller cells to release ATP, leading to activation of P2X7 purinergic receptors on retinal microglia and their subsequent expression of inflammatory cytokines. Importantly, the requirement of Müller cell–specific CD40 expression to recapitulate the appearance of acellular capillaries in diabet ...
... induces Müller cells to release ATP, leading to activation of P2X7 purinergic receptors on retinal microglia and their subsequent expression of inflammatory cytokines. Importantly, the requirement of Müller cell–specific CD40 expression to recapitulate the appearance of acellular capillaries in diabet ...
Novocastra™ Liquid Mouse Monoclonal Antibody Muscle Specific
... Should be examined after the positive tissue control to verify the specificity of the labeling of the target antigen by the primary antibody. Recommended negative control tissue is cerebellum. Alternatively, the variety of different cell types present in most tissue sections frequently offers negati ...
... Should be examined after the positive tissue control to verify the specificity of the labeling of the target antigen by the primary antibody. Recommended negative control tissue is cerebellum. Alternatively, the variety of different cell types present in most tissue sections frequently offers negati ...
not currently active, names provided by Division Head
... born early in gestation. One main project focuses on understanding why newborns are highly susceptible to infections. This is achieved specifically by investigating mechanisms for inflammatory Toll-like receptor-mediated hypo-responses in babies born prematurely, using cell immunology, flow cytometr ...
... born early in gestation. One main project focuses on understanding why newborns are highly susceptible to infections. This is achieved specifically by investigating mechanisms for inflammatory Toll-like receptor-mediated hypo-responses in babies born prematurely, using cell immunology, flow cytometr ...
3: Cellular Level Experiments
... When information in the form of electrical or chemical impulses arrives at the cell membrane, the membrane binding as well as permeability to calcium is altered and the subsequent transport of calcium across the membrane transfers the information signal to the interior of the cell. Because of this f ...
... When information in the form of electrical or chemical impulses arrives at the cell membrane, the membrane binding as well as permeability to calcium is altered and the subsequent transport of calcium across the membrane transfers the information signal to the interior of the cell. Because of this f ...
Highly multiplexed profiling of single
... which is conserved throughout the cell activation process and prevails as it is extended to other Toll-like receptor (TLR) ligands and to primary human macrophages. The results indicate that the phenotypically similar cell population could still exhibit a large degree of intrinsic heterogeneity at t ...
... which is conserved throughout the cell activation process and prevails as it is extended to other Toll-like receptor (TLR) ligands and to primary human macrophages. The results indicate that the phenotypically similar cell population could still exhibit a large degree of intrinsic heterogeneity at t ...
Definition Symptoms Causes
... breaks down proteins. This action causes myeloma cells to die. Both medications are administered through a vein in your arm. Biological therapy. Biological therapy drugs use your body's immune system to fight myeloma cells. The drugs thalidomide (Thalomid), lenalidomide (Revlimid) and pomalidomide ( ...
... breaks down proteins. This action causes myeloma cells to die. Both medications are administered through a vein in your arm. Biological therapy. Biological therapy drugs use your body's immune system to fight myeloma cells. The drugs thalidomide (Thalomid), lenalidomide (Revlimid) and pomalidomide ( ...
A proposal for a simple and inexpensive therapeutic cancer
... on or turn off T-cell responses.) Evidence to support this approach is found in 100-year-old studies on the immunotherapy of cancer. Also, I draw on some remarkable, but little-known studies from the 1960s–1990s, demonstrating that the preparation has already been trialled in humans (although not in ...
... on or turn off T-cell responses.) Evidence to support this approach is found in 100-year-old studies on the immunotherapy of cancer. Also, I draw on some remarkable, but little-known studies from the 1960s–1990s, demonstrating that the preparation has already been trialled in humans (although not in ...
DAMPs, PAMPs and alarmins: all we need to know
... response to inflammatory stimuli, including the detection of PAMPs) illustrates nicely the convergence of the molecular mechanisms that are brought into action by both infection and trauma. A further turn to this story is that cytolytic cells (antigen-specific CTLs or NK cells) cause the release of ...
... response to inflammatory stimuli, including the detection of PAMPs) illustrates nicely the convergence of the molecular mechanisms that are brought into action by both infection and trauma. A further turn to this story is that cytolytic cells (antigen-specific CTLs or NK cells) cause the release of ...
Development of an enhanced bovine viral diarrhea virus subunit
... responses induced against many different antigens, either using recombinant subunit proteins or DNA vaccination5,13 . E2 is the major glycoprotein of BVDV envelope and the most immunogenic protein of this virus. Neutralizing antibodies induced in infected animals are mainly directed against E26 . Th ...
... responses induced against many different antigens, either using recombinant subunit proteins or DNA vaccination5,13 . E2 is the major glycoprotein of BVDV envelope and the most immunogenic protein of this virus. Neutralizing antibodies induced in infected animals are mainly directed against E26 . Th ...
Lecture on Inflammation and Innate Immunity
... • Agents that block TNF are effective in treating rheumatoid arthritis, Crohn’s disease, etc. • Agents that block IL-1 are less effective for these diseases but are useful for some genetic inflammatory diseases (and are currently in clinical trials for more common conditions) ...
... • Agents that block TNF are effective in treating rheumatoid arthritis, Crohn’s disease, etc. • Agents that block IL-1 are less effective for these diseases but are useful for some genetic inflammatory diseases (and are currently in clinical trials for more common conditions) ...
Polyclonal B cell response
Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.