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Chicken Pox
Chicken Pox

... – Immunoglobulin G (IgG) – Immunoglobulin M (IgM) – Immunoglobulin A (IgA) ...
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Chapter 50

... • Promote release of vasoactive substances; activation of complement system and phagocytosis • Act in concert with other components of the ...
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VCE BIOLOGY 2011 LARA SECONDARY COLLEGE COURSE

... This unit examines the molecules and biochemical processes that are essential for life. DNA and gene expression, protein structure / function and associated technologies are explored. Cellular communication, including the immune systems response to pathogens is investigated, as well as the impact bi ...
SBI 3CW - TeacherWeb
SBI 3CW - TeacherWeb

... 2. Viruses do not contain DNA or RNA. 3. Viruses do not contain a cell membrane, nucleus, or cytoplasm. 4. Viruses are destroyed by antibiotics. 5. The genetic material from viruses can direct the host cell to produce new viruses. Multiple Choice 6. Injecting a person with plasma antibodies from a p ...
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Ch 43-45 PPT

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Low-Dose Naltrexone (LDN) for Mood Regulation and
Low-Dose Naltrexone (LDN) for Mood Regulation and

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... across the finish line for two main reasons — they were tested in the wrong patients and did not always generate an immune response due to poor conjugation. MyVax was an autologous idiotype protein coupled to keyhole limpet hemocyanin carrier protein (KLH) given with GM-CSF. It failed a Phase III tr ...
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... virus’ finger prints. They are not strong enough to cause illness (most of the time) but are strong enough to activate an immune response. When a foreign body (bacteria or virus) first enters the body, white blood cells detect them through these antigens since they are not your made up of your own b ...
Immunological diagnosis
Immunological diagnosis

... appropriate Ab, they clump together and eventually form masses that become large enough to be seen. b. Types direct agglutination reaction indirect agglutination reaction ...
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Cancer immunotherapy



Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.
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