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Anatomy – structure
Anatomy – structure

plant tissues: vascular system
plant tissues: vascular system

... The Vascular System: For plants to survive, they must…  take in nutrients & water from environment  transport water up to the leaves, and glucose back down for storage The plant’s vascular system is their “circulatory system” designed to transport materials with the plant! ...
Hematopoiesis Hematopoiesis Hematopoiesis Apoptosis
Hematopoiesis Hematopoiesis Hematopoiesis Apoptosis

... • Progenitor commitment depends on the influence of growth factors and cytokines • In bone marrow stromal cells support the growth and differentiation of hematopoietic cells  direct contact or growth factors. • Stromal cells – meshwork of fat cells, endothelial cells, fibroblasts & MΦs. • Hematopoi ...
Powerpoint - UCSF Immunology Program
Powerpoint - UCSF Immunology Program

... mechanisms and is surprisingly effective, but changes little based on life experience • In innate immunity, limited numbers of distinct receptors; recognize highly conserved features of classes of microbes. • Adaptive immunity learns from previous experience and hence can protect better upon a secon ...
Microbiology 204: Cellular and Molecular Immunology
Microbiology 204: Cellular and Molecular Immunology

IMMUNOTHERAPY
IMMUNOTHERAPY

Establishment of a Plasma Cell Culture and Analysis of Expression of... Olaide Adekanbi, Tim Weeden, Michele Youd IMD Discovery, Genzyme Corporation Introduction
Establishment of a Plasma Cell Culture and Analysis of Expression of... Olaide Adekanbi, Tim Weeden, Michele Youd IMD Discovery, Genzyme Corporation Introduction

... Plasma cells are a part of the human body’s humoral immune response. During an active humoral immune response, B cells, a subset of white blood cells, differentiate into antibody secreting cells after they have become stimulated by an antigen. In various autoimmune disorders, defective plasma cells ...
Immunology - Lecture 2 Adaptive Immune System 1
Immunology - Lecture 2 Adaptive Immune System 1

... Surface protein isolated from leukocytes Þ immunized mice Þ tested antibody Different antibodies recognized same differentiation antigens= antibodies grouped into clusters of differentiation (CD) Surface molecules were called “differentiation antigens” ICAM-1 = CD54 Siglec-1 = CD169 integrin beta ch ...
Document
Document

... molecules (protein, glycoprotein, or polysaccharide) on the surface of cells and viruses C. Pathogen: any antigen that causes a disruption in homeostasis a.k.a. normal, disease free, functions D. Antibody: a protein produced specifically in response to the presence of an antigen - neutralizes antige ...
LECTURE OUTLINE
LECTURE OUTLINE

Immune System Practice Questions
Immune System Practice Questions

Lecture 2 Prenatal Development
Lecture 2 Prenatal Development

Ch 43 Notes
Ch 43 Notes

... Lymphocytes that mature in the thymus above the heart are called T cells, and those that mature in bone marrow are called B cells ...
Immune System Review
Immune System Review

... 6. Antibodies functions include complement fixation and antigen neutralization, precipitation, and agglutination 7. Monoclonal antibodies are pure preparations of single antibody type useful in diagnostic tests and treating some cancers CELLULAR IMMUNE RESPONSE 1. MHC proteins and antigen presentati ...
The Immune System
The Immune System

... c All cells have the same genetic material, but different cells use different active genes to make them function differently < Click on Animation Link to learn how gene segments are combined to produce a large number of diverse antibodies > ...
Innate immunity/ cont…II.Second line: 2.Phagocytosis:
Innate immunity/ cont…II.Second line: 2.Phagocytosis:

...  The macrophages produce cytokines as IL-1 & TNF.These activate endothelial cells of nearby venules to produce adhesion molecules (selectin, integrins, & ICAM) and chemkines (e.g.,IL-8) which mediate MIGRATION of leucocytes & monocytes from the blood to tissues (diapedesis).  The phagocytes have ...
Cells and Basketball
Cells and Basketball

... When you shoot a basketball many parts of your body work together to help you make the shot! These different parts are made up of different tissues and cells. Each type of cell is specialized to perform its job in shooting a basketball. Cells can be specialized in their shape and the organelles that ...
Harnessing the immune system to combat cancer
Harnessing the immune system to combat cancer

... development. TReg cells can be depleted by targeting the IL-2 receptor with the antiCD25 (IL-2 receptor α-chain) antibody daclizumab, the recombinant IL-2–diphtheria toxin conjugate denileukin diftitox or low-dose treatment with the chemotherapeutic cyclophosphamide. However, the lack of specificity ...
Innate Immune Response
Innate Immune Response

Introduction to immunology
Introduction to immunology

...  Chemotaxis (attraction of cells to sites of infection  Opsonization (facilitation of phagocytosis)  Promotion of killing of microorganisms  Increased blood flow  Increased blood vessel permeability  Damage to plasma membranes  Release of inflammatory mediators from mast cells ...
Apoptosis vs Necrosis
Apoptosis vs Necrosis

... Necrosis is caused by external factors, such as infection, toxins or trauma. This is in contrast to apoptosis, which is a naturally occurring cause of cellular death. While apoptosis often provides beneficial effects to the organism, necrosis is almost always detrimental, and can be fatal. For examp ...
Inflammation in CNS
Inflammation in CNS

... Inflammation in the brain is a condition characterized by the presence of an array of molecules (cytokines and established mediators of inflammation) that are not detectable or are barely detectable in physiologic conditions. These molecules are classically produced by cells of the immune system in ...
T cell receptors
T cell receptors

... The RAG-1/2 excises DNA loops. (“throw-away” loops of DNA have been found in thymocytes) Each rearranged DNA sequence will encode a single type of TCR. ...
Immunity - Seattle Central College
Immunity - Seattle Central College

... bacterial cells or antibodies Leads to chain rxn activation of neighboring compliments & inflammation, phagocytosis, and lysis ...
Irreversible cell injury
Irreversible cell injury

... • involution of hormone-dependent tissues upon hormone withdrawal. (endometrium and breast after pregnancy) • Cell loss in proliferating cell populations. (GIT) • Death of host cells after serving their useful function. (neutrophils and lymphocytes in inflammation) • Elimination of potentially harmf ...
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Adoptive cell transfer

Adoptive cell transfer (ACT) is the transfer of cells into a patient; as a form of cancer immunotherapy. The cells may have originated from the patient him- or herself and then been altered before being transferred back, or, they may have come from another individual. The cells are most commonly derived from the immune system, with the goal of transferring improved immune functionality and characteristics along with the cells back to the patient. Transferring autologous cells, or cells from the patient, minimizes graft-versus-host disease (GVHD) or what is more casually described as tissue or organ rejection.
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