Ch 1 section headings and legends
... to the luminal surface of the epithelial cell where the poly-immunoglobulin receptor is cleaved. This releases the dimeric IgA, with a portion of the receptor known as the secretory piece, which renders the IgA less susceptible to proteolytic degradation. ...
... to the luminal surface of the epithelial cell where the poly-immunoglobulin receptor is cleaved. This releases the dimeric IgA, with a portion of the receptor known as the secretory piece, which renders the IgA less susceptible to proteolytic degradation. ...
TGF-beta 3 (E.coli derived) Human E. coli
... The three mammalian isoforms of TGF-beta, TGF-beta1, beta2, and beta3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility, as well as synthesis and deposition of the extra ...
... The three mammalian isoforms of TGF-beta, TGF-beta1, beta2, and beta3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility, as well as synthesis and deposition of the extra ...
NOD-Like Receptors
... Danger-Associated Host Components Uric Acid Crystals Hemozoin ??? Meylan et al. Nature July 2006 ...
... Danger-Associated Host Components Uric Acid Crystals Hemozoin ??? Meylan et al. Nature July 2006 ...
AIDS - Home
... • Reverse-transcriptase inhibitors interfere with copying of viral RNA into DNA by the enzyme reverse transcriptase – Drugs substitute a nucleoside analog that resembles normal nucleosides used by virus to construct DNA – Virus cannot distinguish between analog and normal nucleoside interrupting vir ...
... • Reverse-transcriptase inhibitors interfere with copying of viral RNA into DNA by the enzyme reverse transcriptase – Drugs substitute a nucleoside analog that resembles normal nucleosides used by virus to construct DNA – Virus cannot distinguish between analog and normal nucleoside interrupting vir ...
Mucosal Immunity Part 2
... – IL-10 -/– IL-10R -/– TGFb -/– IL-2 -/– Transgenic TNF – IL-12p40-KO mice are resistant • Long interpreted to mean that Th1 cells mediate pathology in IBD, CD - anti-IL-12p40 used in humans to treat CD! ...
... – IL-10 -/– IL-10R -/– TGFb -/– IL-2 -/– Transgenic TNF – IL-12p40-KO mice are resistant • Long interpreted to mean that Th1 cells mediate pathology in IBD, CD - anti-IL-12p40 used in humans to treat CD! ...
lecture_33_Apr-02_Evasion of immunity
... Plasmodium ookinetes develop in serosal membrane & are beyond reach of phagocytic cells (hemocytes). 3. Antigenic variation. In Plasmodium, different stages of the life cycle express different antigens.. Antigenic variation also occurs in the extracellular protozoan, Giardia lamblia, and in the tryp ...
... Plasmodium ookinetes develop in serosal membrane & are beyond reach of phagocytic cells (hemocytes). 3. Antigenic variation. In Plasmodium, different stages of the life cycle express different antigens.. Antigenic variation also occurs in the extracellular protozoan, Giardia lamblia, and in the tryp ...
Contraction of lymphatic vessels
... antigens) are not antigenic, but link up with our own proteins ...
... antigens) are not antigenic, but link up with our own proteins ...
Principal component analysis and correlative adaptometry used in
... The immune system is very important in overcoming the influence of harmful factors by human organism. This is one of the three integrative systems of the organism, which provides maintenance of homeostasis together with the nervous and endocrine systems [1]. The immune system is a unique natural prot ...
... The immune system is very important in overcoming the influence of harmful factors by human organism. This is one of the three integrative systems of the organism, which provides maintenance of homeostasis together with the nervous and endocrine systems [1]. The immune system is a unique natural prot ...
• Successful parasites have evolved strategies for survival
... Plasmodium ookinetes develop in serosal membrane & are beyond reach of phagocytic cells (hemocytes). 3. Antigenic variation. In Plasmodium, different stages of the life cycle express different antigens.. Antigenic variation also occurs in the extracellular protozoan, Giardia lamblia, and in the tryp ...
... Plasmodium ookinetes develop in serosal membrane & are beyond reach of phagocytic cells (hemocytes). 3. Antigenic variation. In Plasmodium, different stages of the life cycle express different antigens.. Antigenic variation also occurs in the extracellular protozoan, Giardia lamblia, and in the tryp ...
HOST and the MICROBE
... Privileged sites (CNS, joints, testes, placenta, cysts, host DNA) Mimicry (e.g., streptococci and cardiac muscle) Antigen uptake ...
... Privileged sites (CNS, joints, testes, placenta, cysts, host DNA) Mimicry (e.g., streptococci and cardiac muscle) Antigen uptake ...
Poster
... allows for the interaction with the MYPPPY loop of CTLA-4. Phe-31 is at the center of the ring, and seems to play a role in the binding properties of B72 to CTLA-4. The aromatic ring of Phe-31 backs up against the pyrrolidine ring of Pro-102 on CTLA-4, giving significant binding energy and presumabl ...
... allows for the interaction with the MYPPPY loop of CTLA-4. Phe-31 is at the center of the ring, and seems to play a role in the binding properties of B72 to CTLA-4. The aromatic ring of Phe-31 backs up against the pyrrolidine ring of Pro-102 on CTLA-4, giving significant binding energy and presumabl ...
ACQUIRED (SECONDARY) IMMUNODEFICIENCIES
... AIDS is the disease caused by infection with HIV and is characterized by profound immunosuppression with associated opportunistic infections and malignant tumors, wasting, and central nervous system (CNS) degeneration. HIV infects a variety of cells of the immune system, including CD4+ helper T c ...
... AIDS is the disease caused by infection with HIV and is characterized by profound immunosuppression with associated opportunistic infections and malignant tumors, wasting, and central nervous system (CNS) degeneration. HIV infects a variety of cells of the immune system, including CD4+ helper T c ...
Antibody Structure and Function
... • Epitopes are generally hydrophilic regions of an antigen. – Epitopes recognized by B cells are linear or conformational regions located on the surface of the antigen that are available for recognition and binding by antibody. – Epitopes recognized by T cells are linear regions of an antigen that h ...
... • Epitopes are generally hydrophilic regions of an antigen. – Epitopes recognized by B cells are linear or conformational regions located on the surface of the antigen that are available for recognition and binding by antibody. – Epitopes recognized by T cells are linear regions of an antigen that h ...
Adaptive Immune Response
... cell that secreted it - paracrine activated helper T cell secretes a cytokine to help the B cell nearby differentiate into an antibody-secreting cell Can act on the cell that secreted it- autocrine activated T helper cell secretes a cytokine that helps it to proliferate ...
... cell that secreted it - paracrine activated helper T cell secretes a cytokine to help the B cell nearby differentiate into an antibody-secreting cell Can act on the cell that secreted it- autocrine activated T helper cell secretes a cytokine that helps it to proliferate ...
Supplementary Figure 4 - PowerPoint (327 KB )
... the C. elegans total protein lysates. Adult wild-type animals (N2) were fed with bacteria expressing dsRNA against ZK287.5 (the C. elegans homologue of RBX1) for three days, and the protein lysates were probed with RBX1 antibodies at 1:2000 dilution. Compared with lysates from untreated animals, a b ...
... the C. elegans total protein lysates. Adult wild-type animals (N2) were fed with bacteria expressing dsRNA against ZK287.5 (the C. elegans homologue of RBX1) for three days, and the protein lysates were probed with RBX1 antibodies at 1:2000 dilution. Compared with lysates from untreated animals, a b ...
Autoimmune Diseases
... • TSH binds to receptors on the cell membrane of the thyroid gland causing break down of thyroglobulin into T3 and T4 • AutoAbs may interfere with this process and cause under or overactivity of the thyroid • Hashimoto’s thyroditis is most often seen in women between the ages of 30 and 40 years • Pa ...
... • TSH binds to receptors on the cell membrane of the thyroid gland causing break down of thyroglobulin into T3 and T4 • AutoAbs may interfere with this process and cause under or overactivity of the thyroid • Hashimoto’s thyroditis is most often seen in women between the ages of 30 and 40 years • Pa ...
Folie 1 - MH
... 1) cytokines: TGF-β, contributed by IL-2, 4-6, 10 2) ligation of CD40 on B-cell with CD40L on T-cell 2) not essential! ...
... 1) cytokines: TGF-β, contributed by IL-2, 4-6, 10 2) ligation of CD40 on B-cell with CD40L on T-cell 2) not essential! ...
cell is smallest unit of life - life is made out of very complex
... http://www.nobelprize.org/educational/medicine/immunity//immune-detail.html How does our immune system work? How do cells communicate with each other? - The immune system is one of nature's more fascinating inventions. - The immune system is very complex. - It is made up of several types of cells an ...
... http://www.nobelprize.org/educational/medicine/immunity//immune-detail.html How does our immune system work? How do cells communicate with each other? - The immune system is one of nature's more fascinating inventions. - The immune system is very complex. - It is made up of several types of cells an ...
Immunology Cells and organs of the Immune System
... Mediated by a subgroup of leukocytes (white blood cells) that produce cytokines that lead to fibrin clots at the site of inflammation. The inflammatory response results in redness, swelling, heat and pain at the site of the infection Most important outcome is the immobilization of the pathogen at th ...
... Mediated by a subgroup of leukocytes (white blood cells) that produce cytokines that lead to fibrin clots at the site of inflammation. The inflammatory response results in redness, swelling, heat and pain at the site of the infection Most important outcome is the immobilization of the pathogen at th ...
Slide 1
... overreaching/overtraining. Although it naturally follows that infection risk should in some way be linked to acute and chronic exercise-induced alterations in immunity, attempts thus far to measure this association have been unsuccessful. There is growing evidence that for several hours subsequent t ...
... overreaching/overtraining. Although it naturally follows that infection risk should in some way be linked to acute and chronic exercise-induced alterations in immunity, attempts thus far to measure this association have been unsuccessful. There is growing evidence that for several hours subsequent t ...