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The nature of the antigen determine the type of immune response
The nature of the antigen determine the type of immune response

... 3. Special types of antigens a. Heterogenetic (heterophile or heterophile) are a type of xenogeneic antigen. (1) Heterophile antigens occur in different species and have several particular characteristics: (a) They are cross-reacting (i.e., they combine with antibody induced by a different but clos ...
Document
Document

... against infection of body fluids and body cells • Acquired immunity has two branches: the humoral immune response and the cell-mediated immune response • In the humoral immune response antibodies help neutralize or eliminate toxins and pathogens in the blood and lymph • In the cell-mediated immune r ...
Antibody Structure and Function
Antibody Structure and Function

... switch and express a condition called X-linked hyper-IgM syndrome. – IgM only – No memory cell generation ...
HUIMM903cha17
HUIMM903cha17

... Enhancement of tumor cell immunogenicity by transfection of costimulator and cytokine genes ...
Cytokines - University of Arizona
Cytokines - University of Arizona

... Most Cytokines are not stored inside cells (exceptions are, for example TGF-b and PDGF which are stored in platelets) The expression of most Cytokines is strictly regulated - factors are usually produced only by activated cells in response to an induction signal Expression is normally transient and ...
Hazard Analysis and Critical Control Points – A Primer
Hazard Analysis and Critical Control Points – A Primer

... Hygiene Hypothesis – Proposed Mode of Action/Mechanism • Allergic diseases are caused by inappropriate immunological responses to innocuous antigens driven by a TH2 type of immune response. • Many bacteria and viruses elicit a TH1 type of immune response which has the ability to down-regulate media ...
Therapeutic Proteins
Therapeutic Proteins

Monoclonal antibodies in ophthalmology
Monoclonal antibodies in ophthalmology

Ch. 16 Outline
Ch. 16 Outline

Document
Document

... Describe the different functions performed by the two subpopulations of NK cells in the blood and how they are distinguished. B. How does this compare with NK-cell subpopulations in other tissues? 3–38 The function of uterine NK cells (uNK) is to _____. a. kill virus-infected cells b. secrete growth ...
LAMIQ - Open Medicine
LAMIQ - Open Medicine

... Longitudinal analysis of mucosal immune quiescence and impact of commercial sex work in HIV Exposed Seronegative (HESN) sex workers from Nairobi, Kenya ...
Genetically Engineered Antibodies
Genetically Engineered Antibodies

... Genetic EngineerIng of AntIbodies ...
Immunotherapy
Immunotherapy

... Chmiel KD, Suan D, Liddle C, et al. Resolution of severe ipilimumab-induced hepatitis after antithymocyte globulin therapy. J Clin Oncol 2011; 29:e237. Naidoo J, Wang X, Woo KM, et al. Pneumonitis in patients treated with anti-programmed death-1/programmed death ligand 1 therapy. J Clin Oncol 2016. ...
Tumor immunity
Tumor immunity

6. ABO and H Blood Groups
6. ABO and H Blood Groups

... The H gene codes for the production of fucosyl transferase that catalyzes the addition of L-fucose, the immunodominant structure of H antigen, to two slightly different structures, known as the type 1 and type 2 precursor chains. The H gene and its allele h are inherited independently of the allelic ...
Influence of Linex and Enterosgel on humoral immunity in patients
Influence of Linex and Enterosgel on humoral immunity in patients

... Study results for antiendotoxin humoral immunity in CP patients are shown in the Table. In both groups, IgG and IgM levels did not significantly differ from the normal level in all study phases and did not change significantly during the treatment, which matches with the results of our previous stud ...
B Lymphocytes
B Lymphocytes

... proliferative expansion of antigen-activated lymphocytes is therefore one of the crucial properties of adaptive immune responses. Adaptive immunity in humans and other mammals is based on two major lymphocyte subsets, namely B cells and T cells. These two cell types, although they have much in commo ...
NATIONAL CHENG KUNG UNIVERSITY MEDICAL COLLEGE
NATIONAL CHENG KUNG UNIVERSITY MEDICAL COLLEGE

... genes, diversity or D genes, and joining or JH genes. There are a number of genes in each group. During the embryonic development of a particular B cell lineage (clonal), but prior to contact with antigen, this segment of chromosome undergoes a rearrangement whereby one VH gene, one D gene and one J ...
PPT - UCLA Health
PPT - UCLA Health

... complement, cell lysis. Autoimmune hemolytic anemia. • Type III - Immune complex - Ig and Ag form immune complex deposited in normal tissues, activate complement, inflammation, neutrophil influx, tissue injury – vasculitis, lupus, RA • Type IV - delayed hypersensitivity - T cell mediated, antibody i ...
Clopidogrel Bicarbonate-Platelet Inhibitor Plavix
Clopidogrel Bicarbonate-Platelet Inhibitor Plavix

... Contraindications: Plavix is contraindicated with persons with active bleeding, such as peptic ulcer; not to be used with tipinovir (a protease HIV medication); not to be used with proton pump inhibitors, such as acid relievers (this can affect how the drug is eliminated from your body); discuss use ...
Sickle-Cell Anemia
Sickle-Cell Anemia

... Sickle red blood cells become hard, sticky and shaped like sickles used to cut wheat. When these hard and pointed red cells go through the small blood tube, they clog the flow and break apart. This can cause pain, damage and a low blood count, or anemia. ...
Chapter 22: The Lymphatic System and Immunity
Chapter 22: The Lymphatic System and Immunity

... system. They can be caused by poor development of lymphoid tissues/organs, viral infections, and/or immunity-suppressing (immunosuppressive) drugs. The human immunodeficiency virus (HIV) causes immune deficiency by destroying helper T cells. While this is not fatal in and of itself, reductions in TH ...
Arjun Bhargava - Tumor Tropism: A Silver Buller?
Arjun Bhargava - Tumor Tropism: A Silver Buller?

... significant therapeutic effect (S H Seo). Importantly, regional secretion is required for both of these proteins to have effect: systemic administration alone was not enough for any therapeutic result (S H Seo). In another case, MSCs expressing TRAIL induce caspasemediated apoptosis in tumor cells t ...
Lecture 3: Introduction of immune system II - BIDD
Lecture 3: Introduction of immune system II - BIDD

... • Many long membrane extensions • Highly variable depending on location ...
A one-protein signaling pathway in the innate immune system
A one-protein signaling pathway in the innate immune system

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Immunosuppressive drug

For a list of immunosuppressive drugs, see the transplant rejection page.Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to: Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver) Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, sarcoidosis, focal segmental glomerulosclerosis, Crohn's disease, Behcet's Disease, pemphigus, and ulcerative colitis). Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control).A common side-effect of many immunosuppressive drugs is immunodeficiency, because the majority of them act non-selectively, resulting in increased susceptibility to infections and decreased cancer immunosurveillance. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, lipodystrophy, moon face, liver and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.Immunosuppressive drugs can be classified into five groups: glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs.
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