NATURAL KILLER CELL ANTIBODY RECEPTOR ENGAGEMENT
... defense against donated organs. There are two major types of allograft rejection: antibody-mediated rejection (ABMR), and T cell-mediated rejection (TCMR). Whereas the incidence of T cell mediated rejection is effectively mitigated by immunosuppression, ABMR remains difficult to control and is thus ...
... defense against donated organs. There are two major types of allograft rejection: antibody-mediated rejection (ABMR), and T cell-mediated rejection (TCMR). Whereas the incidence of T cell mediated rejection is effectively mitigated by immunosuppression, ABMR remains difficult to control and is thus ...
Fc lessons from murine mercury-induced autoimmunity. -receptors in systemic autoimmune conditions -
... hyporesponsiveness (anergy) in lymphocytes, which encounter antigen in the absence of the co-stimulatory signals that accompany inflammation [1]. ...
... hyporesponsiveness (anergy) in lymphocytes, which encounter antigen in the absence of the co-stimulatory signals that accompany inflammation [1]. ...
FUNCTIONS AND APPLICATIONS OF EXOSOMES
... Multiple cell lines that release the exosomes in vitro like neuronal cells, fibroblast cells, adipocytes, intestinal epithelial cells and tumor cell lines have been described. In vivo, exosomes are found to be present in many biological fluids like: synovial fluid, breast milk, blood, urine and sali ...
... Multiple cell lines that release the exosomes in vitro like neuronal cells, fibroblast cells, adipocytes, intestinal epithelial cells and tumor cell lines have been described. In vivo, exosomes are found to be present in many biological fluids like: synovial fluid, breast milk, blood, urine and sali ...
Maltose Tetrapalmitate, a Nontoxic
... animals with tumor, with this dose, was 30% compared to 80% in the controls. The size of tumors that developed was about the same in animals treated with 0.1 to 50 /ug MTP. but it was 40 to 50% smaller in MTP-treated animals as compared to controls. Results with B16 indicated that a MTP dose of 10 / ...
... animals with tumor, with this dose, was 30% compared to 80% in the controls. The size of tumors that developed was about the same in animals treated with 0.1 to 50 /ug MTP. but it was 40 to 50% smaller in MTP-treated animals as compared to controls. Results with B16 indicated that a MTP dose of 10 / ...
In vivo antigen challenge in celiac disease identifies a - Direct-MS
... Because α-gliadins induce intestinal inflammation in celiac disease (CD)6, attempts to define ‘toxic’ peptides have focused on peptides from the first fully sequenced α-gliadin, A-gliadin (SwissProt accession number, Q41545)11. In vivo and ex vivo peptide challenge experiments have been unable to id ...
... Because α-gliadins induce intestinal inflammation in celiac disease (CD)6, attempts to define ‘toxic’ peptides have focused on peptides from the first fully sequenced α-gliadin, A-gliadin (SwissProt accession number, Q41545)11. In vivo and ex vivo peptide challenge experiments have been unable to id ...
Pathophysiology and Clinical Spectrum of Infections in Systemic
... They also analyzed the ability of PMNs from patients who had SLE to produce IL-12 in response to LPS with or without IFN-g. Findings showed that PMNs from patients who have SLE have impaired phagocytic efficiency and decreased production of IL12, which is more pronounced in patients who have a histo ...
... They also analyzed the ability of PMNs from patients who had SLE to produce IL-12 in response to LPS with or without IFN-g. Findings showed that PMNs from patients who have SLE have impaired phagocytic efficiency and decreased production of IL12, which is more pronounced in patients who have a histo ...
Pregnancy enhances the innate immune response in experimental cutaneous leishmaniasis through
... women infected subclinically with Leishmania donovani or Leishmania infantum developed overt disease during gestation [9, 10]. This evidence suggests that pregnancy may increase the risk of developing leishmaniasis; however, there are no epidemiological data to confirm this suggestion [11]. On the o ...
... women infected subclinically with Leishmania donovani or Leishmania infantum developed overt disease during gestation [9, 10]. This evidence suggests that pregnancy may increase the risk of developing leishmaniasis; however, there are no epidemiological data to confirm this suggestion [11]. On the o ...
Nature Medicine 10, 1307
... (though not all) of the recognition events are specific for particular molecular species within these categories rather than for the 'molecular pattern' per se. A middle-ofthe-road position seems best here. Dendritic cells as primary translators of the infectious agent—Tlr discourse Since their disc ...
... (though not all) of the recognition events are specific for particular molecular species within these categories rather than for the 'molecular pattern' per se. A middle-ofthe-road position seems best here. Dendritic cells as primary translators of the infectious agent—Tlr discourse Since their disc ...
A Study of the Ebola Virus Glycoprotein
... The Ebola virus (EBOV) is a member of the family, Filoviridae, and is the etiological agent of Ebola hemorrhagic fever (EHF). This disease causes significant morbidity and mortality in humans and non-human primates, with human fatality rates reaching 90% during outbreaks of the Zaire subtype. Curren ...
... The Ebola virus (EBOV) is a member of the family, Filoviridae, and is the etiological agent of Ebola hemorrhagic fever (EHF). This disease causes significant morbidity and mortality in humans and non-human primates, with human fatality rates reaching 90% during outbreaks of the Zaire subtype. Curren ...
Distinct lines of chickens express different splenic cytokine profiles
... The splenic cytokine and chemokine mRNA expression levels observed in the current study support the concept that distinct lines of chickens utilize different systemic immune mechanisms. The broiler hens expressed IFN-γ mRNA, which is involved in macrophage and natural killer thymic (T) cell activati ...
... The splenic cytokine and chemokine mRNA expression levels observed in the current study support the concept that distinct lines of chickens utilize different systemic immune mechanisms. The broiler hens expressed IFN-γ mRNA, which is involved in macrophage and natural killer thymic (T) cell activati ...
Software Modeling of the Complement System and its role in
... I am indebted to my supervisor Dr. Jugal K. Kalita for helping me define my topic in this thesis and having been of invaluable assistance in my endeavors. He has given me constant support and guidance through out. I would like to thank Dr. Karen Newell and Dr. Maria Augusteijn for agreeing to be my ...
... I am indebted to my supervisor Dr. Jugal K. Kalita for helping me define my topic in this thesis and having been of invaluable assistance in my endeavors. He has given me constant support and guidance through out. I would like to thank Dr. Karen Newell and Dr. Maria Augusteijn for agreeing to be my ...
MINISTRY OF HEALTH PROTECTION OF REPUBLIC KAZAKHSTAN
... disciplines. It has a great importance for the practical medicine as 10 % of all diseases are related to skin diseases. 1.3 Method of checkup of a dermatological patient The method of check up of a skin patient has some features different from the method of checkup of patients of other types. Having ...
... disciplines. It has a great importance for the practical medicine as 10 % of all diseases are related to skin diseases. 1.3 Method of checkup of a dermatological patient The method of check up of a skin patient has some features different from the method of checkup of patients of other types. Having ...
Lectins, Mitogens and Agglutinins
... typically contains high titre anti-banana lectin (BanLec-1) IgG4. Lectins can modulate IgE responses to other antigens [hG3 also does this, and there is some evidence that CD23 (the low-affinity IgE receptor) is in itself a C-type lectin.] Dietary lectins can induce the release of IL-4 and IL-13 fro ...
... typically contains high titre anti-banana lectin (BanLec-1) IgG4. Lectins can modulate IgE responses to other antigens [hG3 also does this, and there is some evidence that CD23 (the low-affinity IgE receptor) is in itself a C-type lectin.] Dietary lectins can induce the release of IL-4 and IL-13 fro ...
Slide 1
... 4- chemotherapy and/or radiation therapy are at increased risk of developing NHL. 5- Viruses have been implicated in the pathogenesis of NHL, including the Epstein-Barr virus in Burkett lymphoma 6- Immunodeficiency states that seem to predispose to NHL include congenital immunodeficiency states (e.g ...
... 4- chemotherapy and/or radiation therapy are at increased risk of developing NHL. 5- Viruses have been implicated in the pathogenesis of NHL, including the Epstein-Barr virus in Burkett lymphoma 6- Immunodeficiency states that seem to predispose to NHL include congenital immunodeficiency states (e.g ...
Full-Text PDF
... mRNAs by RNase-L (reviewed in depth by Brennan-Laun et al.) [25]. More closely in line with its antiviral beginnings, the infection-associated role of RNase-L has been expanded in breadth to include antibacterial activity, immune cell regulation, the induction of IFN-β and autophagy, and most recent ...
... mRNAs by RNase-L (reviewed in depth by Brennan-Laun et al.) [25]. More closely in line with its antiviral beginnings, the infection-associated role of RNase-L has been expanded in breadth to include antibacterial activity, immune cell regulation, the induction of IFN-β and autophagy, and most recent ...
informe del instituto quintiles-ims: "outlook for global
... personalized cancer treatments while creating a plethora of ethical dilemmas. Advances are expected to treat a range of diseases by harnessing the microbiome (a person’s own gut bacteria), as well as regenerative cell technologies that include stem cells harvested from one part of the body to use ag ...
... personalized cancer treatments while creating a plethora of ethical dilemmas. Advances are expected to treat a range of diseases by harnessing the microbiome (a person’s own gut bacteria), as well as regenerative cell technologies that include stem cells harvested from one part of the body to use ag ...
CD4+ T Cells Targeting Dominant and Cryptic Epitopes from
... Microbiology, 6, [1506]. DOI: 10.3389/fmicb.2015.01506 Published in: Frontiers in Microbiology ...
... Microbiology, 6, [1506]. DOI: 10.3389/fmicb.2015.01506 Published in: Frontiers in Microbiology ...
Publications_files/Sabiiti et al review 2012
... by Cryptococcus. The interaction between Cryptococcus and epithelial cells lining the alveolar spaces is thus critical in regulating cryptococcal entry into the circulation system. The mechanisms that allow Cryptococcus to penetrate human alveolar cells remain largely uncharacterised. Initial invest ...
... by Cryptococcus. The interaction between Cryptococcus and epithelial cells lining the alveolar spaces is thus critical in regulating cryptococcal entry into the circulation system. The mechanisms that allow Cryptococcus to penetrate human alveolar cells remain largely uncharacterised. Initial invest ...
Capra Colostrum
... milk, its composition is much different and tolerated by the most sensitive individuals…after all, it’s nature’s first food. ...
... milk, its composition is much different and tolerated by the most sensitive individuals…after all, it’s nature’s first food. ...
innate immunity in c. elegans
... C‑type lectins are carbohydrate‑binding proteins that can exhibit very narrow ligand specificity. In mammals, a number of C‑type lectins have established roles in innate immunity. For example, Dectin‑1 is highly expressed on macrophages and recognizes beta‑glucan, a component of the fungal cell wall ...
... C‑type lectins are carbohydrate‑binding proteins that can exhibit very narrow ligand specificity. In mammals, a number of C‑type lectins have established roles in innate immunity. For example, Dectin‑1 is highly expressed on macrophages and recognizes beta‑glucan, a component of the fungal cell wall ...
Original Article
... maternal immune system.13,14 To date, it has not been determined whether any of these TNF superfamily members and their receptors is expressed in maternal decidual cells. BAFF was known as B cell-activating factor belonging to the TNF family, also called B lymphocyte stimulator (BLyS) TNF- and Apop- ...
... maternal immune system.13,14 To date, it has not been determined whether any of these TNF superfamily members and their receptors is expressed in maternal decidual cells. BAFF was known as B cell-activating factor belonging to the TNF family, also called B lymphocyte stimulator (BLyS) TNF- and Apop- ...