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CONTACT DERMATITIS: JOURNAL CLUB
CONTACT DERMATITIS: JOURNAL CLUB

... Develop following prolonged and repeated exposure to irritants Inflammatory cells have role in development of dermatitis Allergen-specific lymphocytes not involved in pathogenesis Prior sensitization is not necessary ...
Answers to WHAT DID YOU LEARN QUESTIONS
Answers to WHAT DID YOU LEARN QUESTIONS

... circular clusters of lymphatic tissue (T-lymphocytes, B-lymphocytes, and macrophages). The red pulp is associated with the venous supply of the spleen. It consists of splenic cords and splenic sinusoids. The white pulp mounts an immune response when needed, while the red pulp serves as a reservoir f ...
Non-specific, B-cells, T
Non-specific, B-cells, T

... Vaccines work via memory B-cells that make the response to a second exposure more rapid Fig 43.15 ...
Neogenesis of Lymphoid Structures and
Neogenesis of Lymphoid Structures and

... in many chronic infectious diseases such as Helicobacterassociated gastritis, chronic HCV hepatitis, and Lyme arthritis. Lymphoid neogenesis is also frequently observed in noninfectious chronic inflammatory diseases, including many autoimmune diseases such as thyroiditis, rheumatoid arthritis, and mu ...
Primary immune responses to human CMV
Primary immune responses to human CMV

... and only detectable after antiviral therapy. ...
A prospective study on fungal infection in children with cancer
A prospective study on fungal infection in children with cancer

... accounted for the majority of infections, as the fungal pathogen isolated was a yeast in nearly 80% of the cases. Similarly, it has been reported that Candida spp. account for 75% of fungal infections in patients with cancer [8]. In the present study, non-albicans Candida species were more predomina ...
Serum amyloid P component (SAP) binds to late apoptotic cells and
Serum amyloid P component (SAP) binds to late apoptotic cells and

... Background: Patients with SLE have an activated type I IFN system, and serum IFN-α levels correlate to both disease activity and severity. We have shown that SLE patients have an IFN-α inducing factor (SLE-IIF) in serum, consisting of anti-DNA antibodies and DNA in complex. The DNA could originate f ...
RUBELLA (GERMAN MEASLES) What is rubella? Rubella, also
RUBELLA (GERMAN MEASLES) What is rubella? Rubella, also

... Rubella virus is spread through close contact with the nose and throat secretion of an infected person especially during coughs and sneezes. What are the symptoms? Symptoms may begin with low-grade fever, aches and pains, redness of eyes, enlarged lymph glands behind ears and at back of head. A rash ...
Role of T Follicular Helper (Tfh) Cells Plasticity in
Role of T Follicular Helper (Tfh) Cells Plasticity in

... phenotype is intermediate between blood and tonsils. Expression of CCR7 in this population is always negative correlated with PD-1, CCXCR5, ICOS. Since CCR 7 downregulation is required for migration of active CD4 T cells from T cell zone to B cell follicle which is concomitant with up-regulation of ...
Vaccinia-Expressed Human Papillomavirus 16 and 18 E6 and E7 as
Vaccinia-Expressed Human Papillomavirus 16 and 18 E6 and E7 as

... SCC.2 Both intraepithelial neoplasia and SCC are commonly associated with HR-HPVs. Indeed, for cervical disease, the development of sensitive PCR methodology has demonstrated HR-HPV to be present in almost all cases of SCC (1), and HR-HPV infection is now widely accepted as a necessary cause for cer ...
Patterns of Use
Patterns of Use

... circulated among the authors, who contributed additional comments. The refined version of the survey was submitted to the survey consultant (Mega Media, Inc.), which made suggested changes in the wording of questions, response options, and item branching, all designed to enhance comprehension. This ...
Limbic Encephalitis - Encephalitis Society
Limbic Encephalitis - Encephalitis Society

... call this “Paraneoplastic” Limbic Encephalitis. Most individuals with PLE will turn out to have a cancer of the lung, thymus gland, the breast or the testis. In many cases, PLE can be diagnosed by testing for one of a group of paraneoplastic autoantibodies in the patient’s blood. The condition may i ...
MINIMAL CHANGES CHOLANGIOPATHY
MINIMAL CHANGES CHOLANGIOPATHY

... a major problem in pediatric liver transplantation - appearance of autoantibodies is associated with a wide spectrum of clinical / histological features ...
Course 20: Alergic disease
Course 20: Alergic disease

... • Accidental injection into fingers occurs. There is a risk of ischaemia and patients should be advised ...
Characterization of novel natural killer (NK)–cell and γδT
Characterization of novel natural killer (NK)–cell and γδT

... 1 month. Therefore, we believe that the technique described here will be generally useful for establishing cell lines from more cases of nasal T/NK-cell lymphomas. The establishment of tumor cell lines appears to have advantages over biopsies for phenotypic and genotypic studies. In phenotypic studi ...
Complex regional pain syndrome complicating total knee arthroplasty
Complex regional pain syndrome complicating total knee arthroplasty

... syndrome–type 1 (CRPS-1) after total knee arthroplasty (TKA) with those of uncomplicated TKA knees and preoperative osteoarthritic knees. Methods. Medical records of 1280 patients who underwent TKA for osteoarthritis were retrospectively reviewed; 8 were diagnosed as having symptoms and signs consis ...
frosted branch angiitis
frosted branch angiitis

... patients with frosted branch angiitis. The cause of central scotoma similar to optic neuritis is likely to be macular edema and exudates rather than direct damage to the optic nerve. The ERG shows reduction in the amplitude of a- and b- wave. Almost no electroretinogram response could be elicited on ...
Immune escape from a graft-versus-leukemia effect may play a role
Immune escape from a graft-versus-leukemia effect may play a role

... respectively). There was no change in the target susceptibility in patients P3 and P4. In patient P2, incubation of the post-transplant but not the pre-transplant leukemia targets with IFN-g induced an increase in the lysis of the posttransplant leukemia to almost pre-BMT levels (E:T at 24:1 rose fr ...
The role of penicillin in benign skin rashes in childhood
The role of penicillin in benign skin rashes in childhood

... antibiotics, with somewhere between 3.6 g and 23 g per 1000 people per day prescribed in Europe.1 In children treated with b-lactams, skin rashes, mostly described as maculopapular or urticarial, are frequently reported by primary care physicians.2 Such rashes are frequently assumed to be a drug-rel ...
A dynamical model of human immune response to influenza A virus
A dynamical model of human immune response to influenza A virus

... (Price et al., 2000). Another role of IFN is to stimulate symptoms such as fever which occurs in the early stages of infection. IFN levels rise rapidly after infection and correlate directly with the degree of viral replication in ferrets, mice and humans (Tamura and Kurata, 2004; Wyde et al., 1982) ...
File
File

... muscle pain, pleurisy, headaches, etc. Some experimentation may be needed to find medication with the least side effect and greatest benefit. Anti-malarials – Hydroxychloroquine is a useful drug in mild to moderate disease and can often control joint symptoms, pleurisy and skin involvement. Benefit ...
Full-Text PDF
Full-Text PDF

... older) in Saudi Arabia has also increased over the past few years and this has been attributed to the improved quality of life, the improved standard of living, and greater access to health care [1]. The health of elderly individuals may be compromised by conditions such as hypertension, arthritis, ...
Chapter 4. Immune responses to foreign antigens
Chapter 4. Immune responses to foreign antigens

... are very efficient cross-linkers of the receptors for antigen on B cells. Route of injection The injection of an antigen intravenously (directly into the blood-stream) is more likely to cause tolerance than injecting the same antigen at a local site, for example intramuscularly or subcutaneously. Ge ...
Rotator Cuff
Rotator Cuff

... • Biomechanical intact cuff is the cuff that restores the equilibrium of the force couples • A cuff tear does not heal conservative • A cuff tear after operative repair may yet not heal • Partial healing may restore sufficient power to the cuff to equilibrate the force couples ...
Folate Deficiency
Folate Deficiency

... absence of IF and HCl secretion. There is association of pernicious anemia with other autoimmune diseases. There is a positive family history for about 30% of patients The histologic appearance of the gastric mucosa (infiltration with plasma cells and lymphocytes) is suggestive of autoimmune-type le ...
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Sjögren syndrome

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