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Spleen-thymus-09
Spleen-thymus-09

... Bilobed organ 50 g at puberty, 10 g in age Epithelial cells and lymphocytes Absent in some immune deficiency states Enlargement: childhood, myasthenia gravis, autoimmune diseases • Tumours: • thymic carcinoid • germ cell tumours • lymphomas (Hodgkin, lymphoblastic lymphoma, large cell lymphoma) • th ...
- Dr. Robert Fox
- Dr. Robert Fox

... in the pathogenesis of fatigue and the adrenal-hypothalmic axis. • In both SS and SLE, we can lower the cytokine ...
Environmental factors in the pathogenesis of autoimmunity
Environmental factors in the pathogenesis of autoimmunity

... MHC class II and I alleles HLA DR3/DR4, HLA B27 Capacity to present antigens and to induce central and peripheral deletion ...
Alzheimer`sDisease_Nguyen
Alzheimer`sDisease_Nguyen

... Ankylosin Spondyltis – joints, ...
Bhargav
Bhargav

... and affects a large area of the skin and one or more internal organs, frequently the kidneys, esophagus, heart and lungs. This form of scleroderma can be quite disabling. There are no treatments for scleroderma itself, but individual organ system complications are treated.[1][2] Other forms of scler ...
Lecture 2 - Autoimmune diseases
Lecture 2 - Autoimmune diseases

... Complement Split products Decreased complement C1q ...
brochure!
brochure!

... HCI has been shown to be effective when ...
Systemic autoimmune diseases
Systemic autoimmune diseases

... and become anergic. • These cells also up-regulate the Fas molecules on their surface. An interaction of these B cells with Fas-ligand-bearing cells results in their death via apoptosis. ...
- Robert Fox, MD, Ph.D.
- Robert Fox, MD, Ph.D.

... We measure blood counts, sedimentation rates and autoantibodies. This gives an idea of the “activity” of the immune system based on lymphocyte hormones. However, these lab tests do not often correlate well with the patient’s symptoms. ...
Document
Document

... Blood vessels Kidney, lung ...
(2) Viral and bacterial superantigens
(2) Viral and bacterial superantigens

... Blood vessels Kidney, lung ...
Expansion of Autoreactive T cells
Expansion of Autoreactive T cells

... Blood vessels Kidney, lung ...
Autoimmunity
Autoimmunity

... Autoimmune disease occurs when an immune response attacks our own tissues. Like all adaptive immune responses, it is focused on specific antigens by T-cell receptors and B cell receptors. In contrast to infection, the antigens that these cells recognise are processed from proteins within the target ...
Document
Document

... Autoimmune disease occurs when an immune response attacks our own tissues. Like all adaptive immune responses, it is focused on specific antigens by T-cell receptors and B cell receptors. In contrast to infection, the antigens that these cells recognise are processed from proteins within the target ...
MU Brno - Masaryk University
MU Brno - Masaryk University

... phagocytosed by macrophages and neutrophils, leading to their activation, formation of reactive oxygen intermediates and release of lysosomal enzymes and thus tissue damage. Rheumatoid factors are IgM which react with the Fc. Complexes are deposited in joints and lead to type III hypersensitivity ...
Who Gets Lupus?
Who Gets Lupus?

... 2. C1q binds to and clears apoptotic blebs (sources of autoantigens) 3. Absence of C1q permits sustained infections that could trigger autoimmune response. ...
PFIZER’S CENTERS FOR THERAPEUTIC INNOVATION (CTI) CTI:
PFIZER’S CENTERS FOR THERAPEUTIC INNOVATION (CTI) CTI:

... interested in novel approaches to treat a variety of diseases associated with immune dysregulation, including proposals describing intervention points to drive the development of immunological tolerance and de novo generation and/or functional enhancement of T regulatory cells ...
Autoimmune Disease
Autoimmune Disease

... the antigen. His immune cells divided and left behind memory cells. When he got infected the second time his memory cells made the secondary immune response fight the disease faster and stronger, so he ...
Document
Document

... 5. The differentiation between „self” and „non-self”. The role of MHC antigens in the immune response TCR - generation of the TCR, structural characteristics of the TCR, role of the TCR in the recognition of antigens 6. Immunotolerance ...
241.Autoimmunity
241.Autoimmunity

... Human immunodeficiency virus (HIV) ...
Homeopathic Approach for Autoimmune Disorders
Homeopathic Approach for Autoimmune Disorders

... tissues from another person or species. The immune system produces antibodies that destroy these harmful substances. In patients with an autoimmune disorder, the immune system cannot tell the difference between healthy body tissue and antigens. The result is an immune response that destroys normal b ...
Disseminated ldiopathic Myositis in Young Marshall Farms Ferrets
Disseminated ldiopathic Myositis in Young Marshall Farms Ferrets

... cells). Another form of immuneDisseminated Idiopathic Myositis mediated anemia can occur if the is a descriptive term for what the immune system damages the bone "disseminated"means diseasedoes: "idiopathic" means marrow, but the anemia in those widespread; (no new "of unknown origin or cause"; and ...
Sjögren`s Syndrome Fact Sheet - Sjogren`s Syndrome Foundation
Sjögren`s Syndrome Fact Sheet - Sjogren`s Syndrome Foundation

... How is Sjögren’s diagnosed? Sjögren’s is often undiagnosed or misdiagnosed. A diagnosis may be difficult because symptoms can vary from person to person and may mimic those of menopause, drug side effects or medical conditions such as lupus, rheumatoid arthritis, fibromyalgia, chronic fatigue, and ...
molecular mimicry - Institute of Pathophysiology
molecular mimicry - Institute of Pathophysiology

... Hashimoto thyreoiditis 2 Histological picture of the thyroid ...
CHRONIC LYMPHOCYTIC LEUKAEMIA CLL
CHRONIC LYMPHOCYTIC LEUKAEMIA CLL

... routine physical exam.or by routine CBC. Clinical manifestation develop as the leukemic cell acumalate on lymph nodes ,liver ,spleen & bone marrow . Presenting problems may be anaemia, infections,painless lymphadenopathy, and systemic symptoms such as night sweats or weight loss. However, these more ...
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Sjögren syndrome

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