X-linked hyper IgM syndrome = CD40 ligand deficiency
... •Interaction of B cells and helper T cells leads to CD40L expression on T cells and IL-4, 5, and 6 production, which drive the proliferation and differentiation of B cell into plasma cells and memory cells •The second signal required to activate antibody production against thymusindependent antigen ...
... •Interaction of B cells and helper T cells leads to CD40L expression on T cells and IL-4, 5, and 6 production, which drive the proliferation and differentiation of B cell into plasma cells and memory cells •The second signal required to activate antibody production against thymusindependent antigen ...
title - JustAnswer
... Yellowish discoloration to gums and moist tissues of the body (known as “icterus” or “jaundice”) and dark urine (known as “pigmenturia”) due to the presence of hemoglobin (a breakdown product of red-blood cells) or bilirubin (a bile pigment that is in increased levels with icterus) ...
... Yellowish discoloration to gums and moist tissues of the body (known as “icterus” or “jaundice”) and dark urine (known as “pigmenturia”) due to the presence of hemoglobin (a breakdown product of red-blood cells) or bilirubin (a bile pigment that is in increased levels with icterus) ...
slide_3
... • Most commonly arise in lymph nodes • If circulates peripheral blood or bone marrow, it is called lymphoid leukemia • They vary widely in their clinical presentation and behavior, low or high-grade lymphomas • Generally classified as Hodgkin and non-Hodgkin lymphomas • Risk factors: immune suppress ...
... • Most commonly arise in lymph nodes • If circulates peripheral blood or bone marrow, it is called lymphoid leukemia • They vary widely in their clinical presentation and behavior, low or high-grade lymphomas • Generally classified as Hodgkin and non-Hodgkin lymphomas • Risk factors: immune suppress ...
presentation (5 MB, )
... “I think it's much more interesting to live not knowing than to have answers which might be wrong. I have approximate answers and possible beliefs and different degrees of uncertainty about different things, but I am not absolutely sure of anything and there are many things I don't know anything abo ...
... “I think it's much more interesting to live not knowing than to have answers which might be wrong. I have approximate answers and possible beliefs and different degrees of uncertainty about different things, but I am not absolutely sure of anything and there are many things I don't know anything abo ...
Beyond tired: Helping patients cope with chronic fatigue syndrome
... (e.g., exhaustion, aches/pains, sore throat, swollen glands, upper respiratory symptoms, decreased appetite) that patients experience all of the time. Symptoms worsen with exertion.5 Core symptoms also include sleep dysfunction and pain, as well as neurological symptoms (e.g., impaired memory and co ...
... (e.g., exhaustion, aches/pains, sore throat, swollen glands, upper respiratory symptoms, decreased appetite) that patients experience all of the time. Symptoms worsen with exertion.5 Core symptoms also include sleep dysfunction and pain, as well as neurological symptoms (e.g., impaired memory and co ...
Lupus Nephritis
... own healthy tissues, leading to inflammation and tissue damage. Symptoms may be limited to the skin, but more often lupus also causes internal problems such as joint pain. In severe cases, it can damage the heart, kidneys, and other vital organs. Although there's no cure, there are treatments that c ...
... own healthy tissues, leading to inflammation and tissue damage. Symptoms may be limited to the skin, but more often lupus also causes internal problems such as joint pain. In severe cases, it can damage the heart, kidneys, and other vital organs. Although there's no cure, there are treatments that c ...
ppt - med.muni
... - association with HLA (DQ, DP) T-lymphocytes produce levels of IL-2 (+ IR-2R) and they are constantly stimulate ...
... - association with HLA (DQ, DP) T-lymphocytes produce levels of IL-2 (+ IR-2R) and they are constantly stimulate ...
Goodpasture Syndrome
... • The 3 principles of therapy in anti–glomerular basement membrane (antiGBM) disease are (1) to rapidly remove circulating antibody, primarily by plasmapheresis; (2) to stop further production of antibodies using immunosuppression with medications; and (3) to remove offending agents that may have in ...
... • The 3 principles of therapy in anti–glomerular basement membrane (antiGBM) disease are (1) to rapidly remove circulating antibody, primarily by plasmapheresis; (2) to stop further production of antibodies using immunosuppression with medications; and (3) to remove offending agents that may have in ...
Cytopenias developing after solid organ transplantation
... Leukopenia by marrow suppression Sirolimus Anemia esp in renal transplant (iron hemostasis, direct anti proliferative effect, IL 10 activation) Azathioprine Anemia/pancytopenia Alemtuzumab: reports of PRCA and immune hemolysis Pure red-cell aplasia : MMF, tacrolimus, azothioprine and A ...
... Leukopenia by marrow suppression Sirolimus Anemia esp in renal transplant (iron hemostasis, direct anti proliferative effect, IL 10 activation) Azathioprine Anemia/pancytopenia Alemtuzumab: reports of PRCA and immune hemolysis Pure red-cell aplasia : MMF, tacrolimus, azothioprine and A ...
D Inflammatory Demyelinating Diseases of the Central Nervous System
... myelin in the PNS. Depending on their origin,these diseases can be divided into two categories. The first,demyelinating conditions, are related to inflammatory, toxic, or metabolic causes. The second,dysmyelinating processes,are mostly of a genetic nature, and involve the progressive loss of myelin ...
... myelin in the PNS. Depending on their origin,these diseases can be divided into two categories. The first,demyelinating conditions, are related to inflammatory, toxic, or metabolic causes. The second,dysmyelinating processes,are mostly of a genetic nature, and involve the progressive loss of myelin ...
Chapter 6 outline
... sensory receptors (touch). They associate with a disclike sensory nerve ending to form the Merkel disc. - 3 – The Melanocytes synthesize the melanin pigments which protect the skin against ultraviolet damage. - 4 – The Langerhan Cells macrophages used in the defense against microorganisms. ...
... sensory receptors (touch). They associate with a disclike sensory nerve ending to form the Merkel disc. - 3 – The Melanocytes synthesize the melanin pigments which protect the skin against ultraviolet damage. - 4 – The Langerhan Cells macrophages used in the defense against microorganisms. ...
Sex hormones and gender disparity in immunity and autoimmunity
... Estrogens modulate the immune system contributing to significant modifications in immune function during the menstrual cycle and pregnancy. They also impact infectious and autoimmune diseases as well as inflammation33-36. Estrogens, in particular 17β estradiol (E2), are able to regulate immune response ...
... Estrogens modulate the immune system contributing to significant modifications in immune function during the menstrual cycle and pregnancy. They also impact infectious and autoimmune diseases as well as inflammation33-36. Estrogens, in particular 17β estradiol (E2), are able to regulate immune response ...
Ocular Surface Disease - SOG-SSO
... • Management: frequent lubrication, cycloplegia, 5% NaCl, therapeutic ...
... • Management: frequent lubrication, cycloplegia, 5% NaCl, therapeutic ...
A rare case of Burkitt`s lymphoma of the duodenal bulb
... and third portions of the duodenum [7,8]. To our knowledge, duodenal Burkitt’s lymphoma affecting only the bulb has not been previously reported in the medical literature. Endoscopic findings are not specific but the documented cases reported a polypoid pattern, donut-shaped lesions, thickened gastr ...
... and third portions of the duodenum [7,8]. To our knowledge, duodenal Burkitt’s lymphoma affecting only the bulb has not been previously reported in the medical literature. Endoscopic findings are not specific but the documented cases reported a polypoid pattern, donut-shaped lesions, thickened gastr ...
Atopic Keratoconjunctivitis
... eczema. Recent evidence suggests that AKC and eczema are not only caused by the classic Type I hypersensitivity (from Gell & Coomb’s original classification system) but also by a Type IV (delayed-type) hypersensitivity. This is supported by the clinical findings that some patients have neither perip ...
... eczema. Recent evidence suggests that AKC and eczema are not only caused by the classic Type I hypersensitivity (from Gell & Coomb’s original classification system) but also by a Type IV (delayed-type) hypersensitivity. This is supported by the clinical findings that some patients have neither perip ...
Discussion on specific indications
... AOM is the most frequent bacterial infection One of the major reason of antimicrobial use ecological impact No consensus regarding the management of AOM across the Europe Several guidelines : watchful-waiting strategy Other guidelines : initial antibiotic treatment if young children or ot ...
... AOM is the most frequent bacterial infection One of the major reason of antimicrobial use ecological impact No consensus regarding the management of AOM across the Europe Several guidelines : watchful-waiting strategy Other guidelines : initial antibiotic treatment if young children or ot ...
Autoimmune disease and infection
... As many as one in 20 people in Europe and North America have some form of autoimmune disease. These diseases arise in genetically predisposed individuals but require an environmental trigger. Of the many potential environmental factors, infections are the most likely cause. Microbial antigens can in ...
... As many as one in 20 people in Europe and North America have some form of autoimmune disease. These diseases arise in genetically predisposed individuals but require an environmental trigger. Of the many potential environmental factors, infections are the most likely cause. Microbial antigens can in ...
GAMUNEX-C Infusion Rate Chart
... Renal dysfunction, acute renal failure, osmotic nephrosis, and death may occur with immune globulin intravenous (IVIG) products in predisposed patients. Patients predisposed to renal dysfunction include those with any degree of preexisting renal insufficiency, diabetes mellitus, age greater than 65, ...
... Renal dysfunction, acute renal failure, osmotic nephrosis, and death may occur with immune globulin intravenous (IVIG) products in predisposed patients. Patients predisposed to renal dysfunction include those with any degree of preexisting renal insufficiency, diabetes mellitus, age greater than 65, ...
GAMUNEX-C Infusion Rate Chart
... Renal dysfunction, acute renal failure, osmotic nephrosis, and death may occur with immune globulin intravenous (IVIG) products in predisposed patients. Patients predisposed to renal dysfunction include those with any degree of preexisting renal insufficiency, diabetes mellitus, age greater than 65, ...
... Renal dysfunction, acute renal failure, osmotic nephrosis, and death may occur with immune globulin intravenous (IVIG) products in predisposed patients. Patients predisposed to renal dysfunction include those with any degree of preexisting renal insufficiency, diabetes mellitus, age greater than 65, ...
FMEA Archive File #22: Failure to Prevent Hypotension
... from Ann Arbor. This form of hypotension has often been termed vasoplegia and prompts the use of methylene blue. One article (Fischer 2010) says the frequency is 5-25%. Another author (Gomes 1994) cites a frequency of vasoplegia at 0.8% which I think is more credible. I really don’t know how to char ...
... from Ann Arbor. This form of hypotension has often been termed vasoplegia and prompts the use of methylene blue. One article (Fischer 2010) says the frequency is 5-25%. Another author (Gomes 1994) cites a frequency of vasoplegia at 0.8% which I think is more credible. I really don’t know how to char ...
Autoimmune Inner Ear Disease (AIED)
... usually progressing rapidly to the second ear. “Autoimmune inner ear disease” is the name used to describe the variety of disorders in which the ear is the sole target of an inappropriate attack by the immune system. This disorder differs from other vestibular disorders because medical treatment can ...
... usually progressing rapidly to the second ear. “Autoimmune inner ear disease” is the name used to describe the variety of disorders in which the ear is the sole target of an inappropriate attack by the immune system. This disorder differs from other vestibular disorders because medical treatment can ...
Omega-3 Fatty Acid-Derived Mediators of Resolution in Health and
... Acute inflammation in the lung is fundamentally important to host defense, but chronic or excessive inflammation leads to several important respiratory diseases, including asthma. The resolution of inflammation is an active process. In health, cell-cell interactions at the onset of acute inflammatio ...
... Acute inflammation in the lung is fundamentally important to host defense, but chronic or excessive inflammation leads to several important respiratory diseases, including asthma. The resolution of inflammation is an active process. In health, cell-cell interactions at the onset of acute inflammatio ...
“The Immune System”
... How does your body know there is an invader? • All pathogens have “distinct” marker proteins that are antigens. • Antigens -anything that causes an immune response. • Your body must recognize antigens as FOREIGN (NON-SELF) in order to create an immune response. ...
... How does your body know there is an invader? • All pathogens have “distinct” marker proteins that are antigens. • Antigens -anything that causes an immune response. • Your body must recognize antigens as FOREIGN (NON-SELF) in order to create an immune response. ...
59 immunology structure and function of immune system
... AIDS. HIV evades detection by hiding in immune cells. It destroys helper T-cells through its direct cytotoxic effects and by triggering cytotoxic T-cells. When helper T-cell counts plummet, susceptibility to opportunistic infections increase, leading to AIDS and eventual death. In autoimmune disease ...
... AIDS. HIV evades detection by hiding in immune cells. It destroys helper T-cells through its direct cytotoxic effects and by triggering cytotoxic T-cells. When helper T-cell counts plummet, susceptibility to opportunistic infections increase, leading to AIDS and eventual death. In autoimmune disease ...