book as PDF - Endocrine Abstracts
... University of Leeds, Leeds, UK. 100 years have passed since Harvey Cushing linked a basophilic pituitary adenoma to bilateral adrenal hyperplasia, and in doing so elegantly depicted the clinical phenotype of “Cushing’s syndrome. Today we are uncovering the molecular basis for these tumours and pione ...
... University of Leeds, Leeds, UK. 100 years have passed since Harvey Cushing linked a basophilic pituitary adenoma to bilateral adrenal hyperplasia, and in doing so elegantly depicted the clinical phenotype of “Cushing’s syndrome. Today we are uncovering the molecular basis for these tumours and pione ...
Elevated HMGB1-related interleukin
... analyzer. Levels of HMGB1, IL-6, IL-10 and TNF-α in plasma, sputum, or cell culture supernatant were measured by ELISA. The blood levels of HMGB1, IL-6, IL-10 and TNF-α, the absolute values of WBC, monocytes and neutrophils, and the percentage of monocytes were significant higher in APTB patients th ...
... analyzer. Levels of HMGB1, IL-6, IL-10 and TNF-α in plasma, sputum, or cell culture supernatant were measured by ELISA. The blood levels of HMGB1, IL-6, IL-10 and TNF-α, the absolute values of WBC, monocytes and neutrophils, and the percentage of monocytes were significant higher in APTB patients th ...
Epitope Specificity of Anti-Citrullinated Protein Antibodies
... has resulted in the characterization of several citrullinated proteins and the development of several assays for detection of ACPA, which is a major breakthrough in the laboratory diagnostics of RA [55]. As a result, several types of ACPAs have been identified, as seen in Table 2. An ACPA originally ...
... has resulted in the characterization of several citrullinated proteins and the development of several assays for detection of ACPA, which is a major breakthrough in the laboratory diagnostics of RA [55]. As a result, several types of ACPAs have been identified, as seen in Table 2. An ACPA originally ...
Rheumatoid Arthritis
... of the hands and feet, although any joint can be involved. In advanced cases of the condition, most joints are become affected. The systemic nature of the condition means that many other organs may become involved as the condition progresses. Examples of extra-articular involvement can include sympt ...
... of the hands and feet, although any joint can be involved. In advanced cases of the condition, most joints are become affected. The systemic nature of the condition means that many other organs may become involved as the condition progresses. Examples of extra-articular involvement can include sympt ...
Arterioscler Thromb Vasc Biol. - Arteriosclerosis, Thrombosis, and
... take up oxidized LDL through the scavenger receptor pathway and initiate an adaptive immune response by possibly presenting lipid antigens on CD 1 receptors6 and peptide antigens on human leukocyte antigen-DR (HLA-DR) receptors.7 The existence of a pre-existing, natural immune response against oxidi ...
... take up oxidized LDL through the scavenger receptor pathway and initiate an adaptive immune response by possibly presenting lipid antigens on CD 1 receptors6 and peptide antigens on human leukocyte antigen-DR (HLA-DR) receptors.7 The existence of a pre-existing, natural immune response against oxidi ...
Diagnosis and Treatment of Demodectic Blepharitis
... that the frequency of demodicosis was significantly increased in patients having phototherapy (20). There are 3 important factors for multiplication of the Demodex spp. hypervascular tissue, poor hygienic conditions, and immune deficiency In our study, 53.3% cases in the demodex positive group and 4 ...
... that the frequency of demodicosis was significantly increased in patients having phototherapy (20). There are 3 important factors for multiplication of the Demodex spp. hypervascular tissue, poor hygienic conditions, and immune deficiency In our study, 53.3% cases in the demodex positive group and 4 ...
Jebmh.com Original Research Article
... Although, not therapeutically active, ethanol in the mouthwash has been proven to produce multiple other effects many of which are not beneficial and unnecessary for the user. These range from a characteristic burning sensation upon contact with oral mucosa by activation of vanilloid receptor-1; a h ...
... Although, not therapeutically active, ethanol in the mouthwash has been proven to produce multiple other effects many of which are not beneficial and unnecessary for the user. These range from a characteristic burning sensation upon contact with oral mucosa by activation of vanilloid receptor-1; a h ...
High Producing Tumor Necrosis Factor Alpha Gene Alleles in
... DHF/DSS and control groups Overall, genotyping of TNF-α, IL-12B and IL-10 gene promoter SNPs was successful in at least 98% (n=396) of the studied patients. The distributions of all gene alleles and genotypes were consistent to the Hardy-Weinberg equilibrium, except for the IL-12B 3’UTR Taq I polymo ...
... DHF/DSS and control groups Overall, genotyping of TNF-α, IL-12B and IL-10 gene promoter SNPs was successful in at least 98% (n=396) of the studied patients. The distributions of all gene alleles and genotypes were consistent to the Hardy-Weinberg equilibrium, except for the IL-12B 3’UTR Taq I polymo ...
Sperm Agglutination, Sperm Shaky Head
... When the BTB were damaged due to infection these antigens come into contact with immunocompetent cells, ASA formation occurs and lead to formation of auto-immunity against own sperms [12]. Bronson [13] reported that the active local immunoregulatory mechanisms start being operative within the testes ...
... When the BTB were damaged due to infection these antigens come into contact with immunocompetent cells, ASA formation occurs and lead to formation of auto-immunity against own sperms [12]. Bronson [13] reported that the active local immunoregulatory mechanisms start being operative within the testes ...
Clinical Practice Guideline - Lymphoma
... In Canadian males and females, the incidence rates for non-Hodgkin lymphoma showed a marked increase by approximately 50% between 1978 and the late 1990s, but have since stabilized.(1) Mortality rates have followed a similar pattern. The clearest risk factor for the disease is immunosuppression asso ...
... In Canadian males and females, the incidence rates for non-Hodgkin lymphoma showed a marked increase by approximately 50% between 1978 and the late 1990s, but have since stabilized.(1) Mortality rates have followed a similar pattern. The clearest risk factor for the disease is immunosuppression asso ...
Probiotics: Health benefits in the mouth
... tend to increase with the advent of more sophisticated research methods utilized in studying the microbe-host interactions. Mechanisms of action explaining beneficial probiotic effects include modulation of host immune response leading to strengthening of the resistance to pathogenic challenge, alte ...
... tend to increase with the advent of more sophisticated research methods utilized in studying the microbe-host interactions. Mechanisms of action explaining beneficial probiotic effects include modulation of host immune response leading to strengthening of the resistance to pathogenic challenge, alte ...
5 Acquired Etiologies of Lacrimal System Obstructions
... junction of the common canaliculus into the lacrimal sac. This valve prevents retrograde flow of fluid from the sac into the canaliculi and fornix. In episodes of dacryocystitis, this valve may swell closed even more tightly. Tears and the infection cannot drain out of the sac into the nose, or to the ...
... junction of the common canaliculus into the lacrimal sac. This valve prevents retrograde flow of fluid from the sac into the canaliculi and fornix. In episodes of dacryocystitis, this valve may swell closed even more tightly. Tears and the infection cannot drain out of the sac into the nose, or to the ...
Successful Prevention of Bacterial Endophthalmitis in Eyes with the
... 30% of cases and 33% of the follow-up time. There were 18 cases of bacterial endophthalmitis, for an overall incidence of 0.027 cases per patient-year (Table 2). Fifteen cases (83%) were due to gram-positive cocci: 10 were due to various streptococci (Group B, viridans streptococci, S. pneumoniae), ...
... 30% of cases and 33% of the follow-up time. There were 18 cases of bacterial endophthalmitis, for an overall incidence of 0.027 cases per patient-year (Table 2). Fifteen cases (83%) were due to gram-positive cocci: 10 were due to various streptococci (Group B, viridans streptococci, S. pneumoniae), ...
Understanding Ankylosing Spondylitis
... Ankylosing spondylitis causes inflammation of the spinal joints and this can lead to severe, chronic pain and discomfort, starting generally in the lower back. In the most advanced cases, disease progression can lead to new bone formation on the spine, causing it to fuse in a fixed, immobile positio ...
... Ankylosing spondylitis causes inflammation of the spinal joints and this can lead to severe, chronic pain and discomfort, starting generally in the lower back. In the most advanced cases, disease progression can lead to new bone formation on the spine, causing it to fuse in a fixed, immobile positio ...
Effects of Ionizing Radiation — UNSCEAR 2006 Report, Volume II
... 3. Remarks concerning organs and tissues of the immune system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . C. Cells and molecules of the immune system. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
... 3. Remarks concerning organs and tissues of the immune system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . C. Cells and molecules of the immune system. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
Powerpoint File
... Ritz et al Extent of surgery and recurrence rate of hidradenitis suppurativa Int J Colorectal Dis 1998;13:164-168. ...
... Ritz et al Extent of surgery and recurrence rate of hidradenitis suppurativa Int J Colorectal Dis 1998;13:164-168. ...
The function of tumour necrosis factor and receptors in models of
... maintaining the arthritogenic response. In an eVort to assess if the TNF expressing synovial fibroblast is suYcient to induce disease, we have recently transferred clones of hTNF expressing synovial fibroblasts into the knee joint of histocompatible normal recipients. Migration of such fibroblasts f ...
... maintaining the arthritogenic response. In an eVort to assess if the TNF expressing synovial fibroblast is suYcient to induce disease, we have recently transferred clones of hTNF expressing synovial fibroblasts into the knee joint of histocompatible normal recipients. Migration of such fibroblasts f ...
THE EFFECT OF INTRAUTERINE AND OBSTETRIC FACTORS ON
... have been shown to exert potent effects on autoimmune disease development in genetically susceptible individuals with a higher incidence of autoimmunity in female gender (Markle et al, 2013). In addition, it has been demonstrated that those adolescents whose mothers either had preeclampsia or placen ...
... have been shown to exert potent effects on autoimmune disease development in genetically susceptible individuals with a higher incidence of autoimmunity in female gender (Markle et al, 2013). In addition, it has been demonstrated that those adolescents whose mothers either had preeclampsia or placen ...
Immunotherapy: Radical treatment of Allergic diseases
... Injections are given weekly until patient reaches the maintenance dose of 0.6 to 0.8ml of 1:100, then interval of 4 to 6 weeks for 3 years Sublingual immunotherapy is administered following a protocol for 3 years ...
... Injections are given weekly until patient reaches the maintenance dose of 0.6 to 0.8ml of 1:100, then interval of 4 to 6 weeks for 3 years Sublingual immunotherapy is administered following a protocol for 3 years ...
Chapter 1 Introduction
... the response system involved in maintenance, mediation and recovery from a stress response. At the onset of an acute stress response, signals from the brain (mainly the limbic system) activate the hypothalamus, to secrete corticotrophin-releasing hormone (CRH). Whether or not a situation is labeled ...
... the response system involved in maintenance, mediation and recovery from a stress response. At the onset of an acute stress response, signals from the brain (mainly the limbic system) activate the hypothalamus, to secrete corticotrophin-releasing hormone (CRH). Whether or not a situation is labeled ...
Molecular Dissection of Psoriasis: Integrating Genetics and Biology
... (Sugiyama et al., 1993), and DAB389IL-2 (Gottlieb et al., 1995). The role of hematopoietic cells in psoriasis is further highlighted by cases of psoriasis caused by or cured by bone marrow transplants, depending on whether the donor or recipient had psoriasis (Gardembas-Pain et al., 1990; Kanamori e ...
... (Sugiyama et al., 1993), and DAB389IL-2 (Gottlieb et al., 1995). The role of hematopoietic cells in psoriasis is further highlighted by cases of psoriasis caused by or cured by bone marrow transplants, depending on whether the donor or recipient had psoriasis (Gardembas-Pain et al., 1990; Kanamori e ...
Vitiligo and alopecia areata: apples and oranges?
... diseases and appears to be required for their pathogenesis, revealed through the efficacy of TNF-a blockers in treating psoriasis (9). While modest TNF-a is reportedly elevated in vitiligo and alopecia areata (31–35), attempts to treat both vitiligo and alopecia areata with TNF-a blockers have been ...
... diseases and appears to be required for their pathogenesis, revealed through the efficacy of TNF-a blockers in treating psoriasis (9). While modest TNF-a is reportedly elevated in vitiligo and alopecia areata (31–35), attempts to treat both vitiligo and alopecia areata with TNF-a blockers have been ...
rajiv gandhi university of health sciences, karnataka, bangalore
... causes. The finding of pubic hair before the age of 8 years with acanthosis nigricans was associated with insulin resistance. Autoimmune acanthosis nigricans may occur in autoimmune diseases, including SLE, due to antibodies to the insulin receptor.12 Improvement of the skin lesions is often the pat ...
... causes. The finding of pubic hair before the age of 8 years with acanthosis nigricans was associated with insulin resistance. Autoimmune acanthosis nigricans may occur in autoimmune diseases, including SLE, due to antibodies to the insulin receptor.12 Improvement of the skin lesions is often the pat ...
SLP26 2011 Dysphagia and the respiratory system
... – What is the nature of the patient’s dysphagia? – How likely is current disease related to dysphagia? – What is risk of future disease due to dysphagia? – Can that risk be lowered? – How? – What if the plan cannot work?? ...
... – What is the nature of the patient’s dysphagia? – How likely is current disease related to dysphagia? – What is risk of future disease due to dysphagia? – Can that risk be lowered? – How? – What if the plan cannot work?? ...
Antimicrobial peptides in lung transplant recipients with bronchiolitis obliterans syndrome
... via alloimmune mechanisms. However, BOS is associated with neutrophilia in both bronchoalveolar lavage (BAL) fluid and on endobronchial biopsy [6–9] rather than a pure lymphocytic infiltrate. Despite the advent of more effective immunosuppression, reductions in the frequency of acute rejection have ...
... via alloimmune mechanisms. However, BOS is associated with neutrophilia in both bronchoalveolar lavage (BAL) fluid and on endobronchial biopsy [6–9] rather than a pure lymphocytic infiltrate. Despite the advent of more effective immunosuppression, reductions in the frequency of acute rejection have ...