Review Article Distinct Functions of Specialized
... human plaques [20, 21], suggesting proatherogenic functions of this DC subset and a function as inflammatory amplifiers. In order to scrutinize the role of pDCs in atherosclerosis we employed a specific pDC-depleting antibody. In line with the notion that pDCs exert proinflammatory effects, we could ...
... human plaques [20, 21], suggesting proatherogenic functions of this DC subset and a function as inflammatory amplifiers. In order to scrutinize the role of pDCs in atherosclerosis we employed a specific pDC-depleting antibody. In line with the notion that pDCs exert proinflammatory effects, we could ...
Dental Caries: A pH-mediated disease
... 42% of children, aged 2-11, have had carious lesions in their primary teeth and 21% of children, aged 6-11, have had carious lesions in their permanent dentition. Approximately 59% of adolescents, aged 12-19, have experienced dental caries and by adulthood, aged 20-75+, well over 92% of those survey ...
... 42% of children, aged 2-11, have had carious lesions in their primary teeth and 21% of children, aged 6-11, have had carious lesions in their permanent dentition. Approximately 59% of adolescents, aged 12-19, have experienced dental caries and by adulthood, aged 20-75+, well over 92% of those survey ...
Relevance of biallelic versus monoallelic
... B-cell subsets, and plasma cells.14-17 It binds the 2 ligands a proliferation inducing ligand (APRIL) and B-cell activating factor (BAFF). These interactions induce class switch recombination (CSR) in human and murine B cells.18-21 TACI⫺/⫺ mice show impaired T cell–independent type II (TI-2) respons ...
... B-cell subsets, and plasma cells.14-17 It binds the 2 ligands a proliferation inducing ligand (APRIL) and B-cell activating factor (BAFF). These interactions induce class switch recombination (CSR) in human and murine B cells.18-21 TACI⫺/⫺ mice show impaired T cell–independent type II (TI-2) respons ...
Exploring ancient and modern medical learning
... by rheumatoid arthritis. Although people of any age can be affected by rheumatoid arthritis, it is observed that women are affected three times more than men and the onset is most frequent between the age of 40 and 50 years. Rheumatoid arthritis initiates with the inflammation of the synovial membra ...
... by rheumatoid arthritis. Although people of any age can be affected by rheumatoid arthritis, it is observed that women are affected three times more than men and the onset is most frequent between the age of 40 and 50 years. Rheumatoid arthritis initiates with the inflammation of the synovial membra ...
OB case presentation
... sounds. No tenderness upon light and deep palpation. Spleen and kidneys not felt. Pelvic: speculum exam showed that cervix is pink, smooth, with no discharge, bleeding or erosions and internal exam showed that the uterus is symmetrical, enlarged to 16 weeks size. Extremities: Extremities warm and wi ...
... sounds. No tenderness upon light and deep palpation. Spleen and kidneys not felt. Pelvic: speculum exam showed that cervix is pink, smooth, with no discharge, bleeding or erosions and internal exam showed that the uterus is symmetrical, enlarged to 16 weeks size. Extremities: Extremities warm and wi ...
Bartholin's Gland Cyst
... vagina at about the 4 and 8 o’clock positions. They have small ducts that open to the outside. The glands produce a fluid that helps protect the tissues around the vagina and provides lubrication during sexual intercourse. Normally, these glands cannot be felt or seen. ...
... vagina at about the 4 and 8 o’clock positions. They have small ducts that open to the outside. The glands produce a fluid that helps protect the tissues around the vagina and provides lubrication during sexual intercourse. Normally, these glands cannot be felt or seen. ...
Pathogenic antibodies to coagulation factors. Part one: Factor VIII
... immune system evolved to discriminate infectious non-self from non-infectious self [12]. This included the development of a specific, adaptive response to infection, which produced two problems. One is how to prevent death from an invading organism during the time it takes for the adaptive response t ...
... immune system evolved to discriminate infectious non-self from non-infectious self [12]. This included the development of a specific, adaptive response to infection, which produced two problems. One is how to prevent death from an invading organism during the time it takes for the adaptive response t ...
A Pilot Study into the Effect of Whisky, Wine and Beer Consumption
... that enamel specimens immersed in citric acid had erosive demineralization by loss of calcium and phosphate ions. In contrast, another study observed that an ingested high single dose of ethanol causes a decrease in the stimulated whole saliva flow rate, calcium concentrations and no change in PO43 ...
... that enamel specimens immersed in citric acid had erosive demineralization by loss of calcium and phosphate ions. In contrast, another study observed that an ingested high single dose of ethanol causes a decrease in the stimulated whole saliva flow rate, calcium concentrations and no change in PO43 ...
The Very Young Patient - Advances in Inflammatory Bowel Diseases
... • Tested 160/163 adult-onset risk genotypes which explain ~ 20% of the genetic susceptibility • 1047 pediatric-onset IBD cases and 1663 healthy controls from RISK study • Replicated 88% CD and 90% UC variants • Sequencing approaches needed for more comprehensive dissection of known risk loci and dis ...
... • Tested 160/163 adult-onset risk genotypes which explain ~ 20% of the genetic susceptibility • 1047 pediatric-onset IBD cases and 1663 healthy controls from RISK study • Replicated 88% CD and 90% UC variants • Sequencing approaches needed for more comprehensive dissection of known risk loci and dis ...
the effect of titanium dioxide nanoparticles on salivary alkaline
... The structural and optical properties of the titanium dioxide nanoparticles (TiO 2NPs) have been investigated using (UV-Vis) spectrophotometer and SEM. The produced nanoparticles show small and about sharp round peaks around 220nm. The produced nanoparticles have a spherical shape with an average pa ...
... The structural and optical properties of the titanium dioxide nanoparticles (TiO 2NPs) have been investigated using (UV-Vis) spectrophotometer and SEM. The produced nanoparticles show small and about sharp round peaks around 220nm. The produced nanoparticles have a spherical shape with an average pa ...
- Journal of Clinical Investigation
... may lead to fibrosis. Genetic, epigenetic, and/or age-related alterations may confer susceptibility to fibrosis. Genetic studies in familial cases of IPF indicate a number of pathways related to protein folding and/or trafficking that may adversely affect the regenerative capacity of the epithelium ...
... may lead to fibrosis. Genetic, epigenetic, and/or age-related alterations may confer susceptibility to fibrosis. Genetic studies in familial cases of IPF indicate a number of pathways related to protein folding and/or trafficking that may adversely affect the regenerative capacity of the epithelium ...
Parathyroid Disease: Diagnosis and Treatment March
... expected (z-score>2), the patient requests surgery, consistent followup is unlikely, a coexistent illness complicates management, or the patient is <50 years old. Indications for surgery in the setting of renal failure include renal osteodystrophy or pathologic fractures, intractable bone pain or pr ...
... expected (z-score>2), the patient requests surgery, consistent followup is unlikely, a coexistent illness complicates management, or the patient is <50 years old. Indications for surgery in the setting of renal failure include renal osteodystrophy or pathologic fractures, intractable bone pain or pr ...
Toxic epidermal necrolysis
... There is no gold standard for the treatment of the underlying pathology; two therapies of SJS/TEN in children are widely accepted, although both arouse controversy. The therapies used most commonly are intravenous immunoglobulins (IVIGs) and corticosteroid pulses [11, 24, 36]. By blocking Fas recept ...
... There is no gold standard for the treatment of the underlying pathology; two therapies of SJS/TEN in children are widely accepted, although both arouse controversy. The therapies used most commonly are intravenous immunoglobulins (IVIGs) and corticosteroid pulses [11, 24, 36]. By blocking Fas recept ...
2013 - August - World Allergy Organization
... were treated with subcutaneous immunotherapy to seminal plasma proteins → (i) 7 women had successful treatment (complete ↓ of symptoms), 2 ‘somewhat successful' (improvement of symptoms compared with baseline), 3 unsuccessful (no improvement of symptoms); (ii) 8 women were able to conceive (5 had te ...
... were treated with subcutaneous immunotherapy to seminal plasma proteins → (i) 7 women had successful treatment (complete ↓ of symptoms), 2 ‘somewhat successful' (improvement of symptoms compared with baseline), 3 unsuccessful (no improvement of symptoms); (ii) 8 women were able to conceive (5 had te ...
Lymphoid follicles in (very) severe COPD: beneficial or harmful? REVIEW
... heterogeneous abnormalities of the lung parenchyma, including infiltration of macrophages and lymphocytes into the lungs, which was most prominent in the subpleural regions, as well as distortion of alveolar structures due to septal thickening [38]. Since the pro-inflammatory cytokines IL-1b, IL-6 a ...
... heterogeneous abnormalities of the lung parenchyma, including infiltration of macrophages and lymphocytes into the lungs, which was most prominent in the subpleural regions, as well as distortion of alveolar structures due to septal thickening [38]. Since the pro-inflammatory cytokines IL-1b, IL-6 a ...
tourette syndrome and related tic disorders
... and on direct examination. Diagnostic criteria for ‘‘Tourette’s disorder’’ (DSM-IV) (11) and ‘‘definite Tourette syndrome’’ (TS Classification Study Group) (12) differ only slightly: both diagnoses require the frequent occurrence of multiple motor tics and one or more vocal tics, over a continuous i ...
... and on direct examination. Diagnostic criteria for ‘‘Tourette’s disorder’’ (DSM-IV) (11) and ‘‘definite Tourette syndrome’’ (TS Classification Study Group) (12) differ only slightly: both diagnoses require the frequent occurrence of multiple motor tics and one or more vocal tics, over a continuous i ...
TNF receptor 2 pathway: drug target for autoimmune diseases
... During the development of autoimmunity, pathological progenitors to T cells and other immune cell types proliferate and mature in the thymus, along with their normal counterparts. Most of these immature immune cells die by apoptosis, an orderly demise that is essential to remove defective immune-cel ...
... During the development of autoimmunity, pathological progenitors to T cells and other immune cell types proliferate and mature in the thymus, along with their normal counterparts. Most of these immature immune cells die by apoptosis, an orderly demise that is essential to remove defective immune-cel ...
Front-end events of Vitamin D deficiency
... The universally shared features as against spatiality are generally considered for diseases definition. However, the most optimum solutions are spatiality dependent, shared by local people than universal. ...
... The universally shared features as against spatiality are generally considered for diseases definition. However, the most optimum solutions are spatiality dependent, shared by local people than universal. ...
Post-thrombotic syndrome: a potential cause of
... had a proximal DVT, and who did not have PTS one year following this diagnosis22. The Ginsberg score was used to evaluate for PTS. Eligible participants were then randomised to receive a below-knee stocking (20 to 30 mmHg compression) or placebo stockings. After approximately five years of follow-up ...
... had a proximal DVT, and who did not have PTS one year following this diagnosis22. The Ginsberg score was used to evaluate for PTS. Eligible participants were then randomised to receive a below-knee stocking (20 to 30 mmHg compression) or placebo stockings. After approximately five years of follow-up ...
Delirium Assessment and Management Critical Concepts
... The disturbance in Criteria A and C are not better explained by another preexisting, established, or evolving neurocognitive disorder and do not occur in the context of a severely reduced level of arousal, such as coma There is evidence from the history, physical examination, or laboratory findings ...
... The disturbance in Criteria A and C are not better explained by another preexisting, established, or evolving neurocognitive disorder and do not occur in the context of a severely reduced level of arousal, such as coma There is evidence from the history, physical examination, or laboratory findings ...
Disease Informatics: Phytates driving from the back
... The universally shared features as against spatiality are generally considered for diseases definition. However, the most optimum solutions are spatiality dependent, shared by local people than universal. ...
... The universally shared features as against spatiality are generally considered for diseases definition. However, the most optimum solutions are spatiality dependent, shared by local people than universal. ...
Understanding Hodgkin Lymphoma
... and collectively form a foundation upon which the blood clots. White blood cells work as part of the immune system to help the body fight off infections. The main types of white blood cells are lymphocytes, granulocytes, and monocytes. There are also three types of granulocytes (neutrophils, basophi ...
... and collectively form a foundation upon which the blood clots. White blood cells work as part of the immune system to help the body fight off infections. The main types of white blood cells are lymphocytes, granulocytes, and monocytes. There are also three types of granulocytes (neutrophils, basophi ...
Prima BioMed Ltd (Form: 6-K, Received: 07/10/2015
... Ridgeback Capital Investments L.P. which will be put to shareholders at an Extraordinary General Meeting (EGM) to be held on 31 July 2015. Ridgeback Capital Investments has built a reputation since its founding by Wayne Holman in 2006 as an astute investor in Life Science companies both in America a ...
... Ridgeback Capital Investments L.P. which will be put to shareholders at an Extraordinary General Meeting (EGM) to be held on 31 July 2015. Ridgeback Capital Investments has built a reputation since its founding by Wayne Holman in 2006 as an astute investor in Life Science companies both in America a ...
David E. Elder, MB, CHB, FRCPA
... conditions need to be discussed in multiple different places. We have taken into account the modern emphasis on pattern recognition in several ways. First, within each chapter, the conditions considered are, when appropriate, organized and discussed along pattern lines. Second, we have, as in the pa ...
... conditions need to be discussed in multiple different places. We have taken into account the modern emphasis on pattern recognition in several ways. First, within each chapter, the conditions considered are, when appropriate, organized and discussed along pattern lines. Second, we have, as in the pa ...
Natural HPV immunity and vaccination strategies
... early events may be derived from studies of regression of genital warts which is associated with an increase in infiltration of macrophages, NK and CD4 + T cells (Coleman et al., 1994). Responders to treatment of warts with IFNg and IFNa 2a showed a marked increase in infiltrating Th1 inflammatory c ...
... early events may be derived from studies of regression of genital warts which is associated with an increase in infiltration of macrophages, NK and CD4 + T cells (Coleman et al., 1994). Responders to treatment of warts with IFNg and IFNa 2a showed a marked increase in infiltrating Th1 inflammatory c ...