VitaminDWiki
... • Addi0onally, 1,25D3 ac0vates the Th2 an0body producing lymphocytes, that through ac0ve feedback signaling turn down the Th1 lymphocytes balancing the response. • All arms of the immune system, Th1, Th2 and Th17, may be up‐regulated if vitamin D deficiency is present The paradoxical effects o ...
... • Addi0onally, 1,25D3 ac0vates the Th2 an0body producing lymphocytes, that through ac0ve feedback signaling turn down the Th1 lymphocytes balancing the response. • All arms of the immune system, Th1, Th2 and Th17, may be up‐regulated if vitamin D deficiency is present The paradoxical effects o ...
The pathogenic role of rheumatoid factor in rheumatoid arthritis
... the Fc region of IgG. Since their discovery, RFs have been the subject of extensive studies not just because of their association with RA, but also because they serve as an excellent model for the regulation and induction of disease-related autoantibodies. Although RFs are normally induced during se ...
... the Fc region of IgG. Since their discovery, RFs have been the subject of extensive studies not just because of their association with RA, but also because they serve as an excellent model for the regulation and induction of disease-related autoantibodies. Although RFs are normally induced during se ...
Workshop summary Primary immunodeficiency diseases: An update
... autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, and immune dysregulation–polyendocrinopathy–enteropathy–X-linked in the table of diseases of immune regulation (Table IV). The updated classification takes into account that the clinical and immunologic spectrum of PIDs might be more va ...
... autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, and immune dysregulation–polyendocrinopathy–enteropathy–X-linked in the table of diseases of immune regulation (Table IV). The updated classification takes into account that the clinical and immunologic spectrum of PIDs might be more va ...
IDIOPATHIC THROMBOCYTOPENIC PURPURA AND
... OBJECTIVES: To review the function of platelets in the blood clotting mechanism. To address, conceptualize and classify thrombocytopenic purpura, especially idiopathic thrombocytopenic purpura (ITP), emphasizing the immunological aspects involved in the etiology of the disease. To address the clinic ...
... OBJECTIVES: To review the function of platelets in the blood clotting mechanism. To address, conceptualize and classify thrombocytopenic purpura, especially idiopathic thrombocytopenic purpura (ITP), emphasizing the immunological aspects involved in the etiology of the disease. To address the clinic ...
Day, M. J. (2016). Cats are not small dogs: Is there an
... It is widely recognized that cats appear to be less frequently affected by arthropod-borne infectious diseases than dogs and share fewer zoonotic pathogens with man. This impression is supported by the relative lack of scientific publications related to feline vector-borne infections. This review ex ...
... It is widely recognized that cats appear to be less frequently affected by arthropod-borne infectious diseases than dogs and share fewer zoonotic pathogens with man. This impression is supported by the relative lack of scientific publications related to feline vector-borne infections. This review ex ...
The gut microbiota and immune-regulation: the fate of
... acetate, propionate and butyrate that keep the gut healthy, but also have beneficial anti-inflammatory effects. The reviews by Richards et al.2 and Correa et al.3 describe a whole mechanistic process by which the microbial SCFAs modulate the innate and adaptive immune system. These articles describe h ...
... acetate, propionate and butyrate that keep the gut healthy, but also have beneficial anti-inflammatory effects. The reviews by Richards et al.2 and Correa et al.3 describe a whole mechanistic process by which the microbial SCFAs modulate the innate and adaptive immune system. These articles describe h ...
Review Cytomegalovirus infection in patients with systemic lupus
... originally show hyper-responsiveness to non-self as well as self-antigens (27). This mechanism may be significant for the development of opportunistic infections in SLE patients, in addition to the important role of immunosuppressive agents. Possible mechanisms of CMV-induced autoimmunity There have ...
... originally show hyper-responsiveness to non-self as well as self-antigens (27). This mechanism may be significant for the development of opportunistic infections in SLE patients, in addition to the important role of immunosuppressive agents. Possible mechanisms of CMV-induced autoimmunity There have ...
When NF-kB is inhibited
... They posess ankyrin-repeats which are necessary for RHD-interaction impedes DNA-binding Upon Signal undergoes dissociation and degradation ...
... They posess ankyrin-repeats which are necessary for RHD-interaction impedes DNA-binding Upon Signal undergoes dissociation and degradation ...
Robertson et al. 2003 Seminal priming
... experiments showing that uterine ‘priming’ with semen can promote implantation and fetal growth in subsequent pregnancies, in a partnerspecific manner (Beer et al., 1975). Consistent with an immunological mechanism, removal of lymph nodes draining the uterus after exposure to semen revoked the effec ...
... experiments showing that uterine ‘priming’ with semen can promote implantation and fetal growth in subsequent pregnancies, in a partnerspecific manner (Beer et al., 1975). Consistent with an immunological mechanism, removal of lymph nodes draining the uterus after exposure to semen revoked the effec ...
Two models of multiple sclerosis: Experimental allergic
... consist of inflammatory demyelination. l n both models there is a genetic influence on susceptibilityhesistance to the development of disease. This has been thoroughly studied in TMEV infection, and it has been found to depend on both major histocompatibility complex (MHC) and non-MHC genes. At leas ...
... consist of inflammatory demyelination. l n both models there is a genetic influence on susceptibilityhesistance to the development of disease. This has been thoroughly studied in TMEV infection, and it has been found to depend on both major histocompatibility complex (MHC) and non-MHC genes. At leas ...
WCIT 2010-Invitation Letter1
... researchers to BIT Life Sciences’ 1st Annual World Congress of Immunodiseases and Therapy 2010 (WCIT-2010) with the theme of “Boosting Health and Vitality”, which will take place in Beijing, China on May 15-17, 2010. With your great contributions in the study and research on immunology, you are expe ...
... researchers to BIT Life Sciences’ 1st Annual World Congress of Immunodiseases and Therapy 2010 (WCIT-2010) with the theme of “Boosting Health and Vitality”, which will take place in Beijing, China on May 15-17, 2010. With your great contributions in the study and research on immunology, you are expe ...
Pathophysiology Multiple Organ Dysfunction Syndrome
... Shortness of breath, Oliguria Day 4: 9/L) ↑ T 39.5 ℃↑WBC ...
... Shortness of breath, Oliguria Day 4: 9/L) ↑ T 39.5 ℃↑WBC ...
AQUATIC ANIMAL DISEASE REPORTING
... World Animal Health Coverage by WAHIS for Terrestrial and Aquatic Animal Diseases in 2009 ...
... World Animal Health Coverage by WAHIS for Terrestrial and Aquatic Animal Diseases in 2009 ...
Host responses in periodontal diseases: a preview
... aggressive periodontitis may be caused by the combined effect of multiple genes interacting with environmental factors. Oxidative stress has been implicated in periodontitis, obesity, type II diabetes, vascular diseases and the events that lead to adverse pregnancy outcome. In recent years, reactive ...
... aggressive periodontitis may be caused by the combined effect of multiple genes interacting with environmental factors. Oxidative stress has been implicated in periodontitis, obesity, type II diabetes, vascular diseases and the events that lead to adverse pregnancy outcome. In recent years, reactive ...
Immune response to fungal infections
... about the relative contribution of humoral and cellular immunity to host defence against fungal infections. For a long time it was considered that cell-mediated immunity (CMI) was important, but humoral immunity had little or no role. However, it is accepted now that CMI is the main mechanism of def ...
... about the relative contribution of humoral and cellular immunity to host defence against fungal infections. For a long time it was considered that cell-mediated immunity (CMI) was important, but humoral immunity had little or no role. However, it is accepted now that CMI is the main mechanism of def ...
Energy regulation and neuroendocrine–immune control in
... necrosis factor (TNF), interleukin (IL)-6 and IL-1b] and parathyroid hormone (PTH)-related peptide are instrumental in increasing bone turnover [32]. Calcium is an essential element for functioning of the immune system, which can be demonstrated by considering human immunodeficiency as a consequence ...
... necrosis factor (TNF), interleukin (IL)-6 and IL-1b] and parathyroid hormone (PTH)-related peptide are instrumental in increasing bone turnover [32]. Calcium is an essential element for functioning of the immune system, which can be demonstrated by considering human immunodeficiency as a consequence ...
Characterization of the T-Cell Response to
... same period. Control subjects were matched for age and sex, had a distribution of HLA genotypes similar to that of the type 1 diabetic patients, and were recruited during seasons similar to those of the patients to avoid possible confounding effects of virus exposure. Characteristics of the subjects ...
... same period. Control subjects were matched for age and sex, had a distribution of HLA genotypes similar to that of the type 1 diabetic patients, and were recruited during seasons similar to those of the patients to avoid possible confounding effects of virus exposure. Characteristics of the subjects ...
Boosting Your Dog`s Immune System DNM
... contains echinacein, a biochemical that protects against germ attack by neutralizing the tissuedissolving enzyme hyaluronidase, produced by many germs. Among the many pharmacological properties reported for Echinacea, the one demonstrated most convincingly is macrophage activation – by increasing pr ...
... contains echinacein, a biochemical that protects against germ attack by neutralizing the tissuedissolving enzyme hyaluronidase, produced by many germs. Among the many pharmacological properties reported for Echinacea, the one demonstrated most convincingly is macrophage activation – by increasing pr ...
Exploring the Homeostatic and Sensory Roles of the Immune System
... release of microvesicles into the synaptic cleft, but in this case loaded with T-cell receptors (39). Also, as the nervous system has major areas for information processing and transmission [ganglia and central nervous system (CNS)], the immune system has lymph nodes and lymphoid organs (thymus and ...
... release of microvesicles into the synaptic cleft, but in this case loaded with T-cell receptors (39). Also, as the nervous system has major areas for information processing and transmission [ganglia and central nervous system (CNS)], the immune system has lymph nodes and lymphoid organs (thymus and ...
An Evolutionary Medicine Approach to Understanding
... health of the young are subject to positive natural selection to increase reproductive success, even if they are detrimental to the health and survival of the elderly [47, 48]. In evolutionary medicine, this understanding, known as antagonistic pleiotropy theory, is explained as follows: ‘Fitness ac ...
... health of the young are subject to positive natural selection to increase reproductive success, even if they are detrimental to the health and survival of the elderly [47, 48]. In evolutionary medicine, this understanding, known as antagonistic pleiotropy theory, is explained as follows: ‘Fitness ac ...
as Adobe PDF - Edinburgh Research Explorer
... core glycan structures) cause deficiencies in cellular growth and function and lead to a variety of debilitating diseases called congenital disorders of glycosylation [10]. In contrast, great diversity in the terminal glycan antennae is common. A well-recognized example of this is the existence of AB ...
... core glycan structures) cause deficiencies in cellular growth and function and lead to a variety of debilitating diseases called congenital disorders of glycosylation [10]. In contrast, great diversity in the terminal glycan antennae is common. A well-recognized example of this is the existence of AB ...
Regulation of mucosal immune responses in effector sites
... the intestinal pathology is suggested by a study in which a high proportion of the variation in weight gain after weaning could be accounted for by variation in indirect indices of mucosal immune responses (villus atrophy, crypt hyperplasia) and direct measures of systemic immune responses to soyabe ...
... the intestinal pathology is suggested by a study in which a high proportion of the variation in weight gain after weaning could be accounted for by variation in indirect indices of mucosal immune responses (villus atrophy, crypt hyperplasia) and direct measures of systemic immune responses to soyabe ...
Helminths in the gastrointestinal tract as modulators of immunity and
... The original Hygiene Hypothesis focused on early life imprinting of the immune system by ...
... The original Hygiene Hypothesis focused on early life imprinting of the immune system by ...
Uchanska-Ziegler, B., Loll, B., Fabian, H., Hee, CS, Saenger, W
... Our X-ray crystallographic experiments with the HLA-B27 subtypes B*27:05 and B*27:09 have recently been extensively reviewed (Ziegler et al., 2009b). Therefore, we will mention here only one particularly striking aspect of these analyses in more detail, namely the influence that a seemingly minor di ...
... Our X-ray crystallographic experiments with the HLA-B27 subtypes B*27:05 and B*27:09 have recently been extensively reviewed (Ziegler et al., 2009b). Therefore, we will mention here only one particularly striking aspect of these analyses in more detail, namely the influence that a seemingly minor di ...
system defence system defence - Pro
... ability to maintain a healthy digestive system by eliminating bad bacteria and with 70% of the immune system located in the digestive tract this is a fundamental aspect of maintaining optimal health. Inulin helps support the growth of beneficial bacteria in the digestive system to help eliminate tox ...
... ability to maintain a healthy digestive system by eliminating bad bacteria and with 70% of the immune system located in the digestive tract this is a fundamental aspect of maintaining optimal health. Inulin helps support the growth of beneficial bacteria in the digestive system to help eliminate tox ...